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28 条记录 (耗时 0.026 秒)

    Protease and process for production and use thereof
    1.
    发明授权
    Protease and process for production and use thereof 失效
    蛋白酶及其生产和使用的方法

    公开(公告)号：US4704359A

    公开(公告)日：1987-11-03

    申请号：US917210

    申请日：1986-10-09

    申请人： Hisayuki Matsuo ,  Kensaku Mizuno ,  Takaharu Tanaka

    发明人： Hisayuki Matsuo ,  Kensaku Mizuno ,  Takaharu Tanaka

    IPC分类号： C12N9/60 ,  C12P21/06 ,  C12R1/85 ,  C12R1/865

    CPC分类号： C12P21/06 ,  C12N9/60 ,  Y10S435/942

    摘要： Disclosed is a new protease having the following properties: (1) it is able to hydrolitically cleave a peptide bond between two adjacent basic amino acids in a peptide chain; (2) it has a molecular weight of about 43,000 as determined by electrophoresis; (3) it is inhibited by phenylmethylsulphonyl fluoride and diisopropyl fluorophosphate, but is not inhibited by monoiodoacetate, p-chloromercuribenzoic acid, ethylenediaminetetraacetic acid, 1,10-phenanthroline, tosyl-L-lysine chloromethyl ketone, and leupeptin. The protese can be produced by culturing Saccharomyces cerevisiae, and recovering purification by conventional methods, and is useful as a processing enzyme for conversion of a prohormone to an active hormone.

    Protease and process for production and use thereof
    2.
    发明授权
    Protease and process for production and use thereof 失效
    蛋白酶及其生产和使用的方法

    公开(公告)号：US4650763A

    公开(公告)日：1987-03-17

    申请号：US722356

    申请日：1985-04-12

    申请人： Hisayuki Matsuo ,  Kensaku Mizuno ,  Takaharu Tanaka

    发明人： Hisayuki Matsuo ,  Kensaku Mizuno ,  Takaharu Tanaka

    IPC分类号： C12N9/60 ,  C12P21/06 ,  C12R1/85 ,  C12R1/865 ,  C12N9/50

    CPC分类号： C12P21/06 ,  C12N9/60 ,  Y10S435/942

    摘要： Disclosed is a new protease having the following properties: (1) it is able to hydrolitically cleave a peptide bond between two adjacent basic amino acids in a peptide chain; (2) it has a molecular weight of about 43,000 as determined by electrophoresis; (3) it is inhibited by phenylmethylsulphonyl fluoride and diisopropyl fluorophosphate, but is not inhibited by monoiodoacetate, p-chloromercuribenzoic acid, ethylenediaminetetraacetic acid, 1,10-phenanthroline, tosyl-L-lysine chloromethyl ketone, and leupeptin. The protease can be produced by culturing Saccharomyces cerevisiae, and recovering purification by conventional methods, and is useful as a processing enzyme for conversion of a prohormone to an active hormone.

    摘要翻译： 公开了具有以下特性的新蛋白酶：（1）能够水解切割肽链中两个相邻碱性氨基酸之间的肽键; （2）通过电泳测定其分子量约为43,000; （3）被苯基甲基磺酰氟和氟代磷酸二异丙酯抑制，但不受单碘乙酸，对氯乙基邻苯二甲酸，乙二胺四乙酸，1,10-菲咯啉，甲苯磺酰-L-赖氨酸氯甲基酮和亮抑酶肽抑制。 可以通过培养酿酒酵母并通过常规方法回收纯化来生产蛋白酶，并且可用作将激素原转化为活性激素的加工酶。

    Process for preparing lipase
    3.
    发明授权
    Process for preparing lipase 失效
    脂肪酶的制备方法

    公开(公告)号：US4791059A

    公开(公告)日：1988-12-13

    申请号：US844389

    申请日：1986-03-17

    申请人： Masahiro Nakao ,  Sumio Asami ,  Takaharu Tanaka ,  Kyoichi Ogura ,  Teruo Amachi ,  Hajime Yoshizumi ,  Hiroshi Ishigooka

    发明人： Masahiro Nakao ,  Sumio Asami ,  Takaharu Tanaka ,  Kyoichi Ogura ,  Teruo Amachi ,  Hajime Yoshizumi ,  Hiroshi Ishigooka

    IPC分类号： C12N9/20 ,  C12P7/64 ,  C12R1/44

    CPC分类号： C12P7/6418 ,  C12N9/20 ,  Y10S435/882

    摘要： This invention relates to a process for preparation of a novel lipase. The process is characterized by culturing a microorganism belonging to Staphylococcus capitis and capable of producing lipase in a culture medium to accumulate lipase in the cultured broth and recovering the lipase from the broth. Since the pH of this lipase is in a slightly alkali region and the lipase substantially completely converts glyceride to fatty acids and glycerin, it is useful for the economic preparation of fatty acids by the hydrolysis of fats or oils.

    摘要翻译： PCT No.PCT / JP85 / 00409 Sec。 371日期：1986年3月17日 102（e）1986年3月17日PCT申请日1985年7月19日PCT公布。 第WO86 / 00925号公报 日本1986年2月13日。本发明涉及新型脂肪酶的制备方法。 该方法的特征在于培养属于葡萄球菌属的炎症微生物，并且能够在培养基中产生脂肪酶以在培养的肉汤中积聚脂肪酶并从肉汤中回收脂肪酶。 由于该脂肪酶的pH处于微碱性区域，脂肪酶基本上完全将甘油酯转化为脂肪酸和甘油，因此通过脂肪或油的水解来经济地制备脂肪酸是有用的。

    COMMAND PROCESSING APPARATUS, METHOD AND INTEGRATED CIRCUIT APPARATUS
    6.
    发明申请
    COMMAND PROCESSING APPARATUS, METHOD AND INTEGRATED CIRCUIT APPARATUS 有权
    指令处理装置，方法和集成电路装置

    公开(公告)号：US20090327571A1

    公开(公告)日：2009-12-31

    申请号：US12159048

    申请日：2006-07-28

    申请人： Nobuyuki Ichiguchi ,  Tetsuji Mochida ,  Ryuta Nakanishi ,  Takaharu Tanaka

    发明人： Nobuyuki Ichiguchi ,  Tetsuji Mochida ,  Ryuta Nakanishi ,  Takaharu Tanaka

    IPC分类号： G06F12/06

    CPC分类号： G06F3/061 ,  G06F3/0659 ,  G06F3/067 ,  G06F13/1605 ,  G06F13/1647 ,  G06F13/1673 ,  G09G5/001

    摘要： A command processing apparatus and method are provided for optimally processing commands issued asynchronously from a plurality of masters to a storage apparatus including a plurality of banks, where each master issues commands for a bank 0 and a bank 1 alternately. The command processing apparatus includes buffer units that obtain commands issued from the plurality of masters, an arbitration unit that arbitrates the obtained commands, and an issuance unit that issues commands to the storage apparatus according to the arbitration. The arbitration unit reads the commands of the plurality of masters obtained in the buffer units, and selects one command as a result of arbitration. The arbitration unit waits until a next command of a master relating to the selected command becomes readable, and reads the next command. The issuance unit consecutively issues the selected command and the read command to the storage apparatus.

    摘要翻译： 提供了一种命令处理装置和方法，用于最佳地处理从多个主机异步发出的包括多个存储体的存储装置的命令，其中每个主机交替地为存储体0和存储体1发出命令。 命令处理装置包括获取从多个主机发出的命令的缓冲器单元，仲裁所获得的命令的仲裁单元和根据仲裁向存储装置发出命令的发布单元。 仲裁单元读取在缓冲器单元中获得的多个主器件的命令，并且作为仲裁结果选择一个命令。 仲裁单元等待直到与所选择的命令相关的主机的下一个命令变得可读，并读取下一个命令。 发行单元将选择的命令和读取命令连续地发送到存储装置。

    Processor capable of efficiently executing many asynchronous event tasks
    7.
    发明授权
    Processor capable of efficiently executing many asynchronous event tasks 失效
    处理器能够有效地执行许多异步事件任务

    公开(公告)号：US06470376B1

    公开(公告)日：2002-10-22

    申请号：US09034198

    申请日：1998-03-03

    申请人： Takaharu Tanaka ,  Kiyoshi Maenobu ,  Kosuke Yoshioka ,  Makoto Hirai ,  Tokuzo Kiyohara

    发明人： Takaharu Tanaka ,  Kiyoshi Maenobu ,  Kosuke Yoshioka ,  Makoto Hirai ,  Tokuzo Kiyohara

    IPC分类号： G06F900

    CPC分类号： G06F9/4881 ,  G06F9/30087 ,  G06F9/3009 ,  G06F9/3851 ,  H04N19/42 ,  H04N19/61

    摘要： The counter 52 is set with an initial value of “1” and is a counter with a maximum value of “4”. This counter 52 increments the count value held by the flip-flop 51 in synchronization with a clock signal so that the count value changes as shown by the progression 1,2,3,4,1,2,3,4. This clock signal is also used by the instruction decode control unit 11 to control the execution of instructions, with the counting by the counter 52 being performed once for each instruction execution performed by the instruction decode control unit 11. The comparator 54 compares the count value counted by the counter 52 with the maximum value “4”, and when the values match, sets the task switching signal chg_task_ex at a “High” value, so that the processing switches to the execution of the next task.

    摘要翻译： 计数器52被设置为初始值“1”，并且是具有最大值“4”的计数器。 该计数器52与时钟信号同步地增加由触发器51保持的计数值，使得计数值如进展1,2,3,4,1,2,3,4所示变化。 指令解码控制单元11还使用该时钟信号来控制指令的执行，计数器52对由指令解码控制单元11进行的每个指令执行一次执行一次计数。比较器54将计数值 由具有最大值“4”的计数器52计数，并且当该值匹配时，将任务切换信号chg_task_ex设置为“高”值，使得处理切换到下一任务的执行。

    Pyrrolidineamide derivatives of acylamino acid and pharmaceutical composition containing the same
    8.
    发明授权
    Pyrrolidineamide derivatives of acylamino acid and pharmaceutical composition containing the same 失效
    酰氨基酸的吡咯烷酰胺衍生物和含有它们的药物组合物

    公开(公告)号：US5198458A

    公开(公告)日：1993-03-30

    申请号：US638148

    申请日：1991-01-09

    申请人： Naoki Higuchi ,  Masayuki Saitoh ,  Masaki Hashimoto ,  Harukazu Fukami ,  Takaharu Tanaka

    发明人： Naoki Higuchi ,  Masayuki Saitoh ,  Masaki Hashimoto ,  Harukazu Fukami ,  Takaharu Tanaka

    IPC分类号： C07D207/16 ,  C07D295/185

    CPC分类号： C07D295/185 ,  C07D207/16

    摘要： A compound of the general formula: ##STR1## wherein m is an integer of 1 to 7,n is 0 or an integer of 1 to 5,R.sup.1 is the phenyl, a substituted phenyl, the phenoxy, a substituted phenoxy or a saturated or unsaturated straight alkyl having 5 to 18 carbon atoms,R.sup.2 is hydrogen atom,R.sup.3 is hydrogen atom, a branched or unbranched alkyl having 3 to 5 carbon atoms, the phenyl, hydroxyphenyl, benzyloxyphenyl, an alkylthio having 1 to 3 carbon atoms in its alkyl moiety, amino, carboxyl, hydroxy, benzyloxy, indolyl or imidazolyl, or R.sup.2 and R.sup.3 together form a single bond between the carbon atom and the nitrogen atom, and a pharmaceutical composition containing said compound are provided. The compound is effective in curing amnesia because of its anti-prolyl endopeptidase activity.

    摘要翻译： 一种通式如下的化合物：其中m为1〜7的整数，n为0或1〜5的整数，R 1为苯基，取代苯基，苯氧基，取代的苯氧基或 具有5至18个碳原子的饱和或不饱和直链烷基，R 2是氢原子，R 3是氢原子，具有3至5个碳原子的支链或非支链烷基，苯基，羟基苯基，苄氧基苯基，具有1至3个碳原子的烷硫基 在其烷基部分中，氨基，羧基，羟基，苄氧基，吲哚基或咪唑基，或R2和R3一起形成碳原子和氮原子之间的单键，并提供含有所述化合物的药物组合物。 该化合物由于其抗脯氨酰内肽酶活性而有效地治愈健忘症。

    Command processing apparatus, method and integrated circuit apparatus
    10.
    发明授权
    Command processing apparatus, method and integrated circuit apparatus 有权
    指令处理装置，方法和集成电路装置

    公开(公告)号：US09201819B2

    公开(公告)日：2015-12-01

    申请号：US12159048

    申请日：2006-07-28

    申请人： Nobuyuki Ichiguchi ,  Tetsuji Mochida ,  Ryuta Nakanishi ,  Takaharu Tanaka

    发明人： Nobuyuki Ichiguchi ,  Tetsuji Mochida ,  Ryuta Nakanishi ,  Takaharu Tanaka

    IPC分类号： G06F12/06 ,  G06F13/16 ,  G09G5/00

    CPC分类号： G06F3/061 ,  G06F3/0659 ,  G06F3/067 ,  G06F13/1605 ,  G06F13/1647 ,  G06F13/1673 ,  G09G5/001

    摘要： A command processing apparatus and method are provided for optimally processing commands issued asynchronously from a plurality of masters to a storage apparatus including a plurality of banks, where each master issues commands for a bank 0 and a bank 1 alternately. The command processing apparatus includes buffer units that obtain commands issued from the plurality of masters, an arbitration unit that arbitrates the obtained commands, and an issuance unit that issues commands to the storage apparatus according to the arbitration. The arbitration unit reads the commands of the plurality of masters obtained in the buffer units, and selects one command as a result of arbitration. The arbitration unit waits until a next command of a master relating to the selected command becomes readable, and reads the next command. The issuance unit consecutively issues the selected command and the read command to the storage apparatus.

    摘要翻译： 提供了一种命令处理装置和方法，用于最佳地处理从多个主机异步发出的包括多个存储体的存储装置的命令，其中每个主机交替地为存储体0和存储体1发出命令。 命令处理装置包括获取从多个主机发出的命令的缓冲器单元，仲裁所获得的命令的仲裁单元和根据仲裁向存储装置发出命令的发布单元。 仲裁单元读取在缓冲器单元中获得的多个主器件的命令，并且作为仲裁结果选择一个命令。 仲裁单元等待直到与所选择的命令相关的主机的下一个命令变得可读，并读取下一个命令。 发行单元将选择的命令和读取命令连续地发送到存储装置。