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    CATALYTIC DELIVERY NANOSUBSTRATES (CDNS) FOR HIGHLY EFFICIENT DELIVERY OF BIOMOLECULES
    1.
    发明申请
    CATALYTIC DELIVERY NANOSUBSTRATES (CDNS) FOR HIGHLY EFFICIENT DELIVERY OF BIOMOLECULES 审中-公开
    催化输送纳米生物分子（CDNS），用于高效分送生物分子

    公开(公告)号：US20140186426A1

    公开(公告)日：2014-07-03

    申请号：US14234321

    申请日：2012-07-23

    申请人： Hsian-Rong Tseng ,  Hao Wang ,  Kuan-Ju Chen

    发明人： Hsian-Rong Tseng ,  Hao Wang ,  Kuan-Ju Chen

    IPC分类号： A61K47/48

    CPC分类号： A61K47/59 ,  A61K47/54 ,  A61K47/595 ,  A61K47/60 ,  A61K47/6923 ,  A61K47/6925 ,  A61K47/6951 ,  A61K47/6957 ,  A61K48/0008 ,  B82Y5/00 ,  C12N15/87

    摘要： This invention relates, e.g., to a molecular delivery system comprising A. a substrate having a nanostructured surface region which comprises a plurality of nanostructures and, covalently attached to the substrate, multiple copies of a first member of a binding pair; and B. at least one vector nanoparticle which comprises, encapsulated therein, a molecule of interest, and on its surface, multiple copies of second member of the binding pair. Methods of using the molecular delivery system to deliver a molecule of interest to a cell are also described.

    摘要翻译： 本发明涉及例如涉及包含A.具有纳米结构化表面区域的底物的分子递送系统，其包含多个纳米结构并且共价连接到所述底物上，多个拷贝的结合对的第一个成员; 和B.至少一种载体纳米颗粒，其包含在其中包封感兴趣的分子，并且在其表面上包含结合对的第二个成员的多个拷贝。 还描述了使用分子递送系统将感兴趣的分子递送至细胞的方法。

    Method and apparatus for performing an incremental update of a recommendation model
    8.
    发明授权
    Method and apparatus for performing an incremental update of a recommendation model 有权

    公开(公告)号：US09710480B2

    公开(公告)日：2017-07-18

    申请号：US14382434

    申请日：2012-03-09

    申请人： Hao Wang ,  Alvin Chin ,  Hao Wang ,  Hrishikesh Brahmakal ,  Ari Aarnio

    发明人： Hao Wang ,  Alvin Chin ,  Hao Wang ,  Hrishikesh Brahmakal ,  Ari Aarnio

    IPC分类号： G06F17/30

    CPC分类号： G06F17/30174 ,  G06F17/30598 ,  G06F17/30867

    摘要： An approach is provided for determining one or more recommendations based on an incremental update of a recommendation model. An incremental platform causes, at least in part, a categorization of activity information into a plurality of subsets based, at least in part, on one or more user groups, one or more item groups, at least one update time for at least one recommendation model associated with the activity information, or a combination thereof. The incremental platform further processes and/or facilitates a processing of the activity information based, at least in part, on the categorization to determine whether to perform an incremental update of the at least one recommendation model. The incremental platform also determines one or more recommendations based, at least in part, on the at least one recommendation model, the incremental update, or a combination thereof.

    METHOD AND APPARATUS FOR PERFORMING AN INCREMENTAL UPDATE OF A RECOMMENDATION MODEL
    9.
    发明申请
    METHOD AND APPARATUS FOR PERFORMING AN INCREMENTAL UPDATE OF A RECOMMENDATION MODEL 有权
    用于执行建议模型更新更新的方法和装置

    公开(公告)号：US20150220555A1

    公开(公告)日：2015-08-06

    申请号：US14382434

    申请日：2012-03-09

    申请人： Hao Wang ,  Alvin Chin ,  Hao Wang ,  Hrishikesh Brahmakal ,  Ari Aarnio

    发明人： Hao Wang ,  Alvin Chin ,  Hao Wang ,  Hrishikesh Brahmakal ,  Ari Aarnio

    IPC分类号： G06F17/30

    CPC分类号： G06F17/30174 ,  G06F17/30598 ,  G06F17/30867

    摘要： An approach is provided for determining one or more recommendations based on an incremental update of a recommendation model. An incremental platform causes, at least in part, a categorization of activity information into a plurality of subsets based, at least in part, on one or more user groups, one or more item groups, at least one update time for at least one recommendation model associated with the activity information, or a combination thereof. The incremental platform further processes and/or facilitates a processing of the activity information based, at least in part, on the categorization to determine whether to perform an incremental update of the at least one recommendation model. The incremental platform also determines one or more recommendations based, at least in part, on the at least one recommendation model, the incremental update, or a combination thereof.

    摘要翻译： 提供了一种基于推荐模型的增量更新来确定一个或多个建议的方法。 至少部分地，至少部分地基于一个或多个用户组，一个或多个项目组，至少一个建议的至少一个更新时间，至少部分地将活动信息分类为多个子集 与活动信息相关联的模型，或其组合。 至少部分地，所述增量平台进一步处理和/或促进对所述活动信息的处理，所述至少部分地基于所述分类以确定是否执行所述至少一个推荐模型的增量更新。 增量平台还至少部分地基于至少一个推荐模型，增量更新或其组合来确定一个或多个推荐。

    METHOD AND APPARATUS FOR CREATING AN EPHEMERAL SOCIAL NETWORK
    10.
    发明申请
    METHOD AND APPARATUS FOR CREATING AN EPHEMERAL SOCIAL NETWORK 审中-公开
    创造社会网络的方法和装置

    公开(公告)号：US20140012918A1

    公开(公告)日：2014-01-09

    申请号：US14005947

    申请日：2011-03-29

    申请人： Alvin Chin ,  Hao Wang ,  Hao Wang

    发明人： Alvin Chin ,  Hao Wang ,  Hao Wang

    IPC分类号： H04L29/08

    CPC分类号： H04L67/18 ,  G06Q50/01 ,  H04W4/029 ,  H04W4/21

    摘要： An approach is provided for creating a connection between users of a social network. The approach involves determining location information associated with a user and other location information associated with one or more other users. The approach also includes processing the location information and the other location information to cause, at least in part, identification of one or more encounters, one or more encounter patterns, or a combination thereof with respect to the user and the one or more other users. The approach further includes determining to generate at least one recommendation to create at least one social network, at least one social networking relationship, or a combination thereof between the user and at least one of the one or more other users based, at least in part, on the one or more encounters, the one or more encounter patterns, one or more meetings and/or events, or a combination thereof.

    摘要翻译： 提供了一种用于在社交网络的用户之间创建连接的方法。 该方法包括确定与用户相关联的位置信息和与一个或多个其他用户相关联的其他位置信息。 该方法还包括处理位置信息和其他位置信息，以至少部分地使得相对于用户和一个或多个其他用户的一个或多个遭遇，一个或多个遭遇模式或其组合的识别 。 该方法还包括至少部分地确定以产生至少一个建议来创建至少一个社交网络，至少一个社交网络关系或其组合，所述用户与所述一个或多个其他用户中的至少一个之间 一次或多次遭遇，一个或多个遭遇模式，一个或多个会议和/或事件或其组合。