BONE GRAFT MATERIAL
    8.
    发明申请
    BONE GRAFT MATERIAL 审中-公开
    骨折材料

    公开(公告)号:US20110144764A1

    公开(公告)日:2011-06-16

    申请号:US12914772

    申请日:2010-10-28

    摘要: The present disclosure relates to a bone graft material and a bone graft implant formed from the material. In some embodiments, the bone graft implant comprises a porous matrix having a plurality of overlapping and interlocking bioactive glass fibers and a plurality of pores dispersed throughout the matrix, whereby the fibers are characterized by fiber diameters ranging from about 5 nanometers to about 100 micrometers, and the pores are characterized by pore diameters ranging from about 100 nanometers to about 1 millimeter. The implant may be formed into a desired shape for a clinical application. The embodiments may be employed to treat a bone defect. For example, the bone graft material may be wetted and molded into a suitable form for implantation. The implant may then be introduced into a prepared anatomical site.

    摘要翻译: 本公开涉及由该材料形成的骨移植材料和骨移植物植入体。 在一些实施方案中,骨移植物植入物包括具有多个重叠和互锁的生物活性玻璃纤维的多孔基质和分散在整个基质中的多个孔,其中纤维的特征在于纤维直径范围为约5纳米至约100微米, 并且孔的特征在于孔直径范围为约100纳米至约1毫米。 植入物可以形成为期望的形状用于临床应用。 可以采用这些实施例来治疗骨缺损。 例如,骨移植材料可以被润湿并模制成适合的植入形式。 然后将植入物引入制备的解剖部位。

    Dynamic bioactive bone graft material and methods for handling
    10.
    发明授权
    Dynamic bioactive bone graft material and methods for handling 有权
    动态生物活性骨移植材料及其处理方法

    公开(公告)号:US08567162B2

    公开(公告)日:2013-10-29

    申请号:US12914376

    申请日:2010-10-28

    IPC分类号: A61F2/28 B65B3/00

    摘要: The present disclosure relates to a dynamic bioactive bone graft material and a method of handling the material to prepare an implant. In one embodiment, a method of preparing a dynamic bioactive bone graft implant is provided. The method includes the step of providing a porous, fibrous composition of bioactive glass fibers, wherein the fibers are characterized by fiber diameters ranging from about 5 nanometers to about 100 micrometers, and wherein the porosity of the matrix ranges from about 100 nanometers to about 1 millimeter. The porous, fibrous composition is introduced into a mold tray, and a shaped implant is created using the mold tray. The composition may be wetted with a fluid such as saline or a naturally occurring body fluid like blood prior to creating the shaped implant. In another embodiment, the porous, fibrous composition is provided with the mold tray as a kit.

    摘要翻译: 本公开涉及动态生物活性骨移植材料和处理材料以制备植入物的方法。 在一个实施方案中,提供了制备动态生物活性骨移植物植入物的方法。 该方法包括提供生物活性玻璃纤维的多孔纤维组合物的步骤,其中纤维的特征在于纤维直径范围为约5纳米至约100微米,并且其中基质的孔隙率为约100纳米至约1 毫米。 将多孔的纤维组合物引入模具托盘中,并使用模具托盘产生成形植入物。 在产生成形植入物之前,组合物可以用流体如盐水或天然存在的体液如血液润湿。 在另一个实施方案中,多孔纤维组合物作为试剂盒设置有模托盘。