公开(公告)号：US20170266197A1

公开(公告)日：2017-09-21

申请号：US15310070

申请日：2015-05-11

Applicant: Indiana University Research and Technology Corporation ,  Assembly Biosciences, Inc.

Inventor： Adam Zlotnick ,  William W. Turner ,  Lee Daniel Arnold

IPC: A61K31/5377 ,  A61K31/506 ,  G01N33/50 ,  A61K31/445 ,  G01N33/576 ,  A61K45/06 ,  A61K31/18

CPC classification number: A61K31/5377 ,  A61K31/18 ,  A61K31/445 ,  A61K31/506 ,  A61K31/713 ,  A61K45/06 ,  G01N33/5023 ,  G01N33/5032 ,  G01N33/5762 ,  G01N2500/04

Abstract: Described herein are methods for identifying compounds useful for the treatment of infection by hepatitis B virus (HBV) and for identifying compounds useful for the same.

公开(公告)号：US10006913B2

公开(公告)日：2018-06-26

申请号：US14777636

申请日：2014-03-20

Applicant: INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION

Inventor： Adam Zlotnick ,  Lichun Li ,  Michael S. Van Nieuwenhze ,  William W. Turner

IPC: A61B5/00 ,  A61B8/00 ,  A61B10/00 ,  G01N33/569 ,  C09B11/08 ,  C09B11/24 ,  C09B23/02 ,  C09B57/00 ,  C09B57/02 ,  C09B57/10 ,  C12Q1/18 ,  A61K49/00

CPC classification number: G01N33/56983 ,  A61K49/0017 ,  C09B11/08 ,  C09B11/24 ,  C09B23/02 ,  C09B57/00 ,  C09B57/02 ,  C09B57/10 ,  C12Q1/18 ,  G01N2333/02 ,  G01N2500/02 ,  G01N2500/04 ,  G01N2500/10

Abstract: Heteroaryldihydropyrimidine (HAP)-based fluorescent stains (compounds), as well as uses of such stains as diagnostic reagents, viral-tracking agents, and/or tools for drug discovery are described. The present invention relates to heteroaryldihydropyrimidine (HAP)-based fluorescent stains (compounds), as well as uses of such stains as diagnostic reagents, viral-tracking agents, and/or tools for drug discovery.