公开(公告)号：US20210198409A1

公开(公告)日：2021-07-01

申请号：US17133872

申请日：2020-12-24

Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE

Inventor： Ting-Yu SHIH ,  Chia-Chun WANG ,  Lu-Chih WANG ,  Yuan-Kun YU ,  Shu-Fang CHIANG ,  Yi-Ting HSIEH ,  Yu-Chun LIU ,  Jing-Wen TANG

IPC: C08F285/00 ,  C08F283/06

Abstract: A graft polymer is provided, which includes a polymer backbone with a plurality of hydroxy groups, protection group modified histidine grafted onto the side of the polymer backbone, and hydrophilic polymer having terminal reactive group grafted onto the side of the polymer backbone. The graft polymer coating can be applied to metal material to form a composite material, which can be implanted into an organism to reduce adhesion problems.

公开(公告)号：US20200375873A1

公开(公告)日：2020-12-03

申请号：US16730564

申请日：2019-12-30

Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE

Inventor： Ting-Yu SHIH ,  Lu-Chih WANG ,  Yuan-Kun YU ,  Yi-Ting HSIEH ,  Yu-Chun LIU ,  Jing-Wen TANG

IPC: A61K8/73 ,  A61K8/02 ,  A61K8/49 ,  A61K8/06 ,  A61K8/96 ,  A61Q19/08 ,  A61K8/04 ,  A61K9/107 ,  A61K31/728 ,  A61K9/00 ,  A61K31/4172 ,  A61K31/375 ,  A61K8/67 ,  A61K31/015

Abstract: A method for skin care and/or maintenance including applying or administering a preparation to a subject is provided. The preparation includes a biomedical composition, and the biomedical composition includes an effective amount of micelle, wherein the micelle includes a hyaluronic acid and/or a derivative thereof and a modified histidine. The modified histidine is grafted to at least one primary hydroxyl group of the hyaluronic acid and/or the derivative thereof, and a graft ratio of the modified histidine is 1-100%. Moreover, the hyaluronic acid and/or the derivative thereof and the modified histidine form the micelle on a weight percentage of 0.2-300:1.

公开(公告)号：US20140186415A1

公开(公告)日：2014-07-03

申请号：US14132796

申请日：2013-12-18

Applicant: Industrial Technology Research Institute

Inventor： Ting-Yu SHIH ,  Tse-Min TENG ,  Chia-Chun WANG ,  Yu-Hua CHEN ,  Jui-Hsiang CHEN ,  Mei-Ju YANG ,  Shu-Fang CHIANG ,  Yen-Chun CHEN ,  Chia-Ni CHANG

IPC: A61L15/28 ,  A61L15/24 ,  A61L29/04 ,  A61L27/20 ,  A61L27/16 ,  A61L29/16 ,  A61L15/44 ,  A61L27/54

CPC classification number: A61K31/4172 ,  A61K31/715 ,  A61K31/717 ,  A61K31/728 ,  A61K31/765 ,  A61K47/58 ,  A61K47/61 ,  A61L15/24 ,  A61L15/28 ,  A61L15/44 ,  A61L27/16 ,  A61L27/20 ,  A61L27/54 ,  A61L29/041 ,  A61L29/043 ,  A61L29/16 ,  A61L31/042 ,  A61L31/048 ,  A61L31/16 ,  A61L2300/204 ,  A61L2300/434 ,  C08B11/04 ,  C08B11/08 ,  C08B11/20 ,  C08B15/06 ,  C08B37/0072 ,  C08L1/08 ,  C08L1/26 ,  C08L1/284 ,  C08L5/08

Abstract: A polymer composition including a polymer having a hydroxyl group and a histidine or a histidine derivative grafted to the polymer having a hydroxyl group. A polymer material is also provided, including a polymer composition which includes a polymer having a hydroxyl group, and a histidine or a histidine derivative grafted to the polymer having a hydroxyl group.

Abstract translation: 包括具有羟基的聚合物和接枝到具有羟基的聚合物上的组氨酸或组氨酸衍生物的聚合物组合物。 还提供了聚合物材料，包括包含具有羟基的聚合物的聚合物组合物和接枝到具有羟基的聚合物上的组氨酸或组氨酸衍生物。