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公开(公告)号：US20230309944A1
公开(公告)日：2023-10-05
申请号：US18330502
申请日：2023-06-07
申请人： INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE , SORBONNE UNIVERSITE , UNIVERSITÉ PARIS CITÉ , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) , ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS , ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS
发明人： Jean PROVOST , Anikitos GAROFALAKIS , Mathieu PERNOT , Mickaël TANTER , Bertrand TAVITIAN , Thomas VIEL
CPC分类号： A61B6/5247 , A61B6/032 , A61B6/037 , A61B8/06 , A61B8/488 , A61B6/4258 , A61B6/4417 , A61B8/4416 , A61B8/5261 , A61N7/00
摘要： The invention relates to a method for determining at least one property of an object, the method comprising a step of: a) obtaining first data relative to the object by an ultrasound imaging technique imaging the object at a frame rate superior to 300 Hz, characterized in that the method further comprises a step of: b) obtaining second data relative to the object by imaging the object with at least one of a X-ray and a γ-ray, and c) determining the at least one property of the object based on the first data and the second data.
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公开(公告)号：US20180271471A1
公开(公告)日：2018-09-27
申请号：US15763938
申请日：2016-09-29
申请人： INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) , Sorbonne Universite , Universite Paris Diderot - Paris 7 , Centre National de la Recherche Scientifique , ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS , UNIVERSITE PARIS DESCARTES , ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS
发明人： Jean PROVOST , Anikitos GAROFALAKIS , Mathieu PERNOT , Mickaël TANTER , Bertrand TAVITIAN , Thomas VIEL
CPC分类号： A61B6/5247 , A61B6/032 , A61B6/037 , A61B6/4258 , A61B6/4417 , A61B8/06 , A61B8/4416 , A61B8/488 , A61B8/5261 , A61N7/00
摘要： The invention relates to a method for determining at least one property of an object, the method comprising a step of: a) obtaining first data relative to the object by an ultrasound imaging technique imaging the object at a frame rate superior to 300 Hz, characterized in that the method further comprises a step of: b) obtaining second data relative to the object by imaging the object with at least one of a X-ray and a γ-ray, and c) determining the at least one property of the object based on the first data and the second data.
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公开(公告)号：US20210212709A1
公开(公告)日：2021-07-15
申请号：US17057942
申请日：2019-05-24
申请人： CARDIAWAVE SA , INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE , ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS
发明人： Mathieu PERNOT , Daniel SUAREZ
IPC分类号： A61B17/225 , A61B8/14 , A61B8/08 , A61B8/00
摘要： An ultrasonic processing apparatus is provided. The ultrasonic processing apparatus comprises an ultrasonic therapy transducer (ATA) adapted to generate focused ultrasonic waves; an ultrasonic imaging transducer (UID) connected to the ultrasonic therapy transducer; and an electronic system configured to control the ultrasonic therapy transducer so as to emit a pulse train of ultrasonic waves generating a cloud of cavitation bubbles (BC); control the ultrasonic imaging transducer so as to acquire at least one image of the region to be processed; acquire a plurality of echo signals of ultrasonic wave pulses emitted by the ultrasonic therapy transducer captured by the ultrasonic imaging transducer; process the plurality of echo signals so as to reconstruct an image of the cloud of cavitation bubbles; and display said image of the cloud of cavitation bubbles superposed on said image of the region to be processed. The processing includes spatio-temporal filtering.
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公开(公告)号：US20220346749A1
公开(公告)日：2022-11-03
申请号：US17763259
申请日：2020-09-25
申请人： INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE , UNIVERSITE DE PARIS , SORBONNE UNIVERSITÉ , ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS
摘要： Because of the increase of the obesity related diseases, it is desirable to be able to detect a fatty liver and quantify the content in fat for the fatty liver. Known methods are biopsy and magnetic resonance imaging. However, biopsy is an invasive method and magnetic resonance imaging is a complicated method to carry out. The inventors propose a new ultrasonic method, which is more compliant with a regular control of the content in fat for the fatty liver for a subject. This method notably relies on a smart exploitation of the coherence properties of ultrasound pulses applied to the liver. This method has already been validated on sane subjects as providing accurate measurements, notably for fat content.
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公开(公告)号：US20180261127A1
公开(公告)日：2018-09-13
申请号：US15761486
申请日：2016-09-23
申请人： INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE , SORBONNE UNIVERSITÉ , UNIVERSITÉ PARIS DIDEROT - PARIS 7 , ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS
CPC分类号： G09B23/286 , A61B8/00 , A61B8/06 , A61B8/0816 , A61B8/42 , A61B8/4209 , A61B8/483 , G06T7/0012 , G06T2207/10136 , G06T2207/30016 , G16H50/50
摘要： The invention relates to a method for obtaining a numerical model, the numerical model associating at least one objective measurement to a subjective sensation, the method comprising the steps of: a) imaging the at least one area of the brain by using unfocused waves produced by a transcranial ultrasound probe (20), to obtain at least one acquired image of the activity of the area, b) evaluating a physical quantity representative of the activity of the at least one area based on the acquired images, to obtain at least one objective measurement, c) obtaining from the subject at least one numerical value representative of a subjective sensation, and d) determining the numerical model by using the obtained objective measurement and the obtained numerical value.
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公开(公告)号：US20190247011A1
公开(公告)日：2019-08-15
申请号：US16330948
申请日：2017-09-15
申请人： INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE , ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS , UNIVERSITE PARIS DIDEROT - PARIS 7 , SORBONNE UNIVERSITÉ
发明人： Zsolt LENKEI , Mathieu PERNOT , Mickael TANTER , Thomas DEFFIEUX
CPC分类号： A61B8/06 , A61B8/085 , A61B8/0891 , A61B8/14 , A61B8/145 , A61B8/4494 , A61B8/488 , A61B8/5207 , G01S7/52077 , G01S15/8925 , G01S15/8927 , G01S15/8981
摘要： The present invention aims at improving the Doppler imaging of a biological sample comprising blood. For this, it is proposed a method for imaging a biological sample (10), the sample (10) comprising blood (14) comprising diffusors and solid tissue (16), the method comprising obtaining observation, each observation being characterized by a different point spread function associating a signal to each location of the region of interest, the signal comprising a first contribution representative of the diffusors of blood vessels within the location, a second contribution representative of the tissue diffusors and a third contribution representative of blood signal associated to blood diffusors outside of the location, and estimating, for each location, the blood flow by using a statistical analysis.
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公开(公告)号：US20180177487A1
公开(公告)日：2018-06-28
申请号：US15735759
申请日：2016-06-16
申请人： INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) , UNIVERSITÉ PIERRE ET MARIE CURIE (PARIS 6) , UNIVERSITÉ PARIS DIDEROT - PARIS 7 , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE , ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS
CPC分类号： A61B8/4209 , A61B5/0077 , A61B5/0478 , A61B8/0808 , A61B8/0816 , A61B8/145 , A61B8/4411 , A61B8/4416 , A61B8/4461 , A61B8/4488 , A61B8/488 , A61B8/543 , A61B2503/40 , A61B2562/0219
摘要： The invention concerns a detecting apparatus (12) for imaging at least two areas of a brain of a subject (10), the detecting apparatus (12) comprising:—a holder comprising:—a frame (14) devoted to be cemented on the skull of the subject (10), the frame (14) delimitating an inner portion (18) which is transparent to ultrasound waves,—a removable imaging device comprising:—a platform (16) delimitating an inner space (28), the inner space (28) facing the inner portion (18),—a fixing element (30) adapted to temporary fix and lock the platform (16) to the holder,—an ultrasound probe (32), and—a moving stage (34) holding the ultrasound probe (32) and being adapted to move the ultrasound probe (32) within the inner space (28).
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公开(公告)号：US20170181729A1
公开(公告)日：2017-06-29
申请号：US15325103
申请日：2015-07-17
申请人： INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) , UNIVERSITÉ PIERRE ET MARIE CURIE (PARIS 6) , UNIVERSITÉ PARIS DIDEROT - PARIS 7 , ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS
发明人： Mickael TANTER , Mathieu PERNOT
CPC分类号： A61B8/485 , A61B8/0883 , A61B8/461 , A61B8/5207 , G01S7/52022 , G01S7/52042
摘要： The present invention concerns a method for obtaining a functional parameter of a muscle having a part, the method comprising the steps of: a) applying ultrasound waves to the muscle, b) collecting the ultrasound waves retrodiffused by the muscle at a plurality of times, to obtain collected ultrasound waves, c) determining a first plurality of values representative of stiffness values of one part at a first plurality of times by using the collected ultrasound waves, d) determining a second plurality of values representative of deformation values of said part at a second plurality of times by using the collected ultrasound waves, and e) deducing at least one functional parameter based on the first plurality of values and the second plurality of values. The invention also concerns a corresponding device.
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公开(公告)号：US20230225698A1
公开(公告)日：2023-07-20
申请号：US17996094
申请日：2021-04-13
申请人： INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) , Centre National de la Recherche Scientifique (CNRS) , Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris
CPC分类号： A61B8/06 , A61B8/488 , A61B8/5223 , A61B8/0883
摘要： The present invention relates to the field of ultrasounds and imagining of the coronary blood flow of the heart. Patients with coronary microvascular dysfunction (CMD) have poor prognostic with significantly higher rates of cardiovascular events, including hospitalization for heart failure, sudden cardiac death, and myocardial infarction (MI). Despite the urgent clinical need, there are no non-ionizing and non-invasive techniques available in clinic to directly visualize the coronary microvasculature and assess the local coronary microvascular system. Flow imaging remains a difficult task to perform in the heart because of the fast movements of this organ. In order to overcome the limitations of actual imaging methods for the coronary blood flow, the inventors proposed an ultrasound ultrafast imaging method that automatically detect the time periods in which the myocardium velocity is low and estimate the coronary flow velocity and the tissue velocity from the same data acquisition.
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10.发明申请ULTRASONIC METHOD AND DEVICE FOR CHARACTERISING WEAK ANISOTROPIC MEDIA, AND ULTRASONIC PROBE ASSEMBLY FOR SUCH A CHARACTERISATION DEVICE 审中-公开用于表征弱异种介质的超声方法和装置，以及用于这种特征装置的超声波探头组件公开(公告)号：US20160345938A1
公开(公告)日：2016-12-01
申请号：US15115168
申请日：2015-01-12
申请人： CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS - , INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE , ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS
CPC分类号： A61B8/485 , A61B8/085 , A61B8/0858 , A61B8/0883 , A61B8/4281 , A61B8/4483 , A61B8/5223
摘要： A method for characterizing an anisotropic soft medium (C) including fibers and having an outer surface (1), by observing in different propagation directions, the propagation of a divergent shear wave from a central area (10) in the anisotropic soft medium. A propagation parameter of the shear wave is inferred therefrom in each of the propagation directions, and then a direction of the fibers of the anisotropic soft medium, a rheological elasticity parameter are determined in a direction perpendicular to the fibers and a rheological elasticity parameter in the direction of the fibers.
摘要翻译： 通过在不同的传播方向观察来自各向异性软介质中的中心区域（10）的发散剪切波的传播来表征包括纤维并具有外表面（1）的各向异性软介质（C）的方法。 在每个传播方向推断剪切波的传播参数，然后在垂直于纤维的方向上确定各向异性软介质纤维的方向，流变弹性参数和流变弹性参数 纤维方向。
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