公开(公告)号：US20180372601A1

公开(公告)日：2018-12-27

申请号：US15865914

申请日：2018-01-09

Applicant: Intel Corporation

Inventor： Xing Su ,  David J. Liu ,  Kai Wu ,  Kenneth B. Swartz ,  Mineo Yamakawa

IPC: G01N1/40 ,  B01L3/00 ,  G01N35/08 ,  H01F7/20 ,  G01N15/00 ,  G01N35/00 ,  H01F7/06

Abstract: An embodiment of the invention relates to a device for detecting an analyte in a sample. The device comprises a fluidic network and an integrated circuitry component. The fluidic network comprises a sample zone, a cleaning zone and a detection zone. The fluidic network contains a magnetic particle and/or a signal particle. A sample containing an analyte is introduced, and the analyte interacts with the magnetic particle and/or the signal particle through affinity agents. A microcoil array or a mechanically movable permanent magnet is functionally coupled to the fluidic network, which are activatable to generate a magnetic field within a portion of the fluidic network, and move the magnetic particle from the sample zone to the detection zone. A detection element is present which detects optical or electrical signals from the signal particle, thus indicating the presence of the analyte.

公开(公告)号：US20200166440A1

公开(公告)日：2020-05-28

申请号：US16778536

申请日：2020-01-31

Applicant: Intel Corporation

Inventor： Xing Su ,  David J. Liu ,  Kai Wu ,  Kenneth B. Swartz ,  Mineo Yamakawa

IPC: G01N1/40 ,  G01N35/08 ,  B01L3/00

Abstract: An embodiment of the invention relates to a device for detecting an analyte in a sample. The device comprises a fluidic network and an integrated circuitry component. The fluidic network comprises a sample zone, a cleaning zone and a detection zone. The fluidic network contains a magnetic particle and/or a signal particle. A sample containing an analyte is introduced, and the analyte interacts with the magnetic particle and/or the signal particle through affinity agents. A microcoil array or a mechanically movable permanent magnet is functionally coupled to the fluidic network, which are activatable to generate a magnetic field within a portion of the fluidic network, and move the magnetic particle from the sample zone to the detection zone. A detection element is present which detects optical or electrical signals from the signal particle, thus indicating the presence of the analyte.

公开(公告)号：US09863857B2

公开(公告)日：2018-01-09

申请号：US14448141

申请日：2014-07-31

Applicant: INTEL CORPORATION

Inventor： Xing Su ,  David J. Liu ,  Kai Wu ,  Kenneth B. Swartz ,  Mineo Yamakawa

IPC: G01N1/40 ,  G01N35/08 ,  B01L3/00 ,  G01N35/00 ,  G01N15/00 ,  H01F7/20 ,  H01F7/06

CPC classification number: G01N1/4044 ,  B01L3/502761 ,  B01L3/502784 ,  B01L2200/0647 ,  B01L2200/0673 ,  B01L2300/0816 ,  B01L2400/0424 ,  B01L2400/043 ,  B01L2400/0638 ,  B01L2400/086 ,  G01N35/0098 ,  G01N35/08 ,  G01N2015/0038 ,  G01N2015/0092 ,  H01F7/20 ,  H01F7/206 ,  H01F2007/068 ,  Y10S436/805 ,  Y10S436/806 ,  Y10T29/49117 ,  Y10T29/4913 ,  Y10T29/49155 ,  Y10T436/25

Abstract: An embodiment of the invention relates to a device for detecting an analyte in a sample. The device comprises a fluidic network and an integrated circuitry component. The fluidic network comprises a sample zone, a cleaning zone and a detection zone. The fluidic network contains a magnetic particle and/or a signal particle. A sample containing an analyte is introduced, and the analyte interacts with the magnetic particle and/or the signal particle through affinity agents. A microcoil array or a mechanically movable permanent magnet is functionally coupled to the fluidic network, which are activatable to generate a magnetic field within a portion of the fluidic network, and move the magnetic particle from the sample zone to the detection zone. A detection element is present which detects optical or electrical signals from the signal particle, thus indicating the presence of the analyte.