SYSTEMS AND METHODS FOR DELIVERING TARGETED THERAPY

    公开(公告)号:US20230071306A1

    公开(公告)日:2023-03-09

    申请号:US17800279

    申请日:2021-02-18

    IPC分类号: A61B90/00 A61B18/14

    摘要: A computer-assisted medical device is configured and used to endoluminally navigate to a location in the gastrointestinal system and there treat certain body lumen wall areas while avoiding other body lumen wall areas. Embodiments ablate the inner mucosal layer and sub-mucosal nerve plexus of the stomach, duodenum and jejunum to effect treatment of insulin resistance and metabolic disorders, such as Type II diabetes (T2D), polycystic ovarian syndrome (PCOS), non-alcoholic steatohepatitis (NASH), non-alcoholic fatty liver disease (NAFLD), congestive heart failure (CHF) and obstructive sleep apnea (OSA). Various sensors are used to assist a clinical operator to navigate from the mouth through the pyloric sphincter and into and through the duodenum and/or jejunum. Various sensors are used to map and identify portions of the duodenum and/or jejunum. Various lumen wall ablation devices and methods are described. Various post-treatment assessments are described.

    Cooled chokes for ablation systems and methods of use

    公开(公告)号:US11730537B2

    公开(公告)日:2023-08-22

    申请号:US16681255

    申请日:2019-11-12

    IPC分类号: A61B18/18 A61B18/00

    摘要: An antenna system for tissue ablation includes an energy transmission member, an antenna body coupled to the energy transmission member, a fluid source, and a choke member comprising an integrally formed choke body and choke connector electrically coupled to the energy transmission member by the choke connector. The choke body defines an outermost portion of the choke member. The choke body has an axial length and the choke connector extends along a majority of the length of the choke body and contacts the choke body along the majority of the length. The choke connector is in direct contact with a fluid from the fluid source. The choke connector is disposed between the choke body and the energy transmission member. The choke connector forms a delivery path for the fluid between the choke body and the energy transmission member. The choke connector and the choke body are a continuous wire mesh.

    ELONGATE FLEXIBLE SYSTEMS WITH ARTICULATION JOINT ASSEMBLY

    公开(公告)号:US20230128263A1

    公开(公告)日:2023-04-27

    申请号:US17972415

    申请日:2022-10-24

    IPC分类号: A61B17/00

    摘要: A catheter system may comprise an articulation joint including a first pair of links and a second pair of links. Each link may include a central channel enclosed at least in part by radially extending arcuate segments. The first pair of links may include a first link and a second link, and the second pair of links may include the second link and a third link. The system may also comprise a first pair of springs coupled between the first and second links. The system may also comprise a second pair of springs coupled between the second and third links. The system may also include control wires extending through the first pair of springs and a control wires extending through the second pair of springs. The spring walls may share a radial dimension with the link walls.