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公开(公告)号：US06527995B1
公开(公告)日：2003-03-04
申请号：US09610832
申请日：2000-07-06
IPC分类号： D04H154
CPC分类号： C08G18/721 , C08G18/0895 , C08G18/6607 , C08G18/664 , C08G2140/00
摘要： A process for producing a thermoplastic polyurethane film by means of sintering a particulate thermoplastic polyurethane in a heated mold, is described. The thermoplastic polyurethane has: (i) a melt index of 20 to 100, measured at 190° C. and under an applied force of 21.2 N; (ii) a relative solution viscosity of 1.15 to 1.45, the relative solution viscosity being determined by, measuring the viscosity (a) of a solution of 0.4 grams of the thermoplastic polyurethane in 99.7 grams N-methyl-2-pyrrolidone containing 0.1% dibutylamine at 25° C., measuring the viscosity (b) of N-methyl-2-pyrrolidone containing 0.1% dibutylamine at 25° C., and dividing viscosity (a) by viscosity (b); and (iii) a Shore hardness of 80 to 98.
摘要翻译： 描述了通过在加热的模具中烧结颗粒状热塑性聚氨酯来制造热塑性聚氨酯膜的方法。 热塑性聚氨酯具有：（i）在190℃和21.2N的施加力下测量的20至100的熔体指数; （ii）相对溶液粘度为1.15至1.45，相对溶液粘度通过测量在含有0.1％二丁胺的99.7克N-甲基-2-吡咯烷酮中的0.4克热塑性聚氨酯溶液的粘度（a） 在25℃下测量在25℃下含有0.1％二丁胺的N-甲基-2-吡咯烷酮的粘度（b），并将粘度（a）除以粘度（b）。 和（iii）肖氏硬度为80-98。
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公开(公告)号：US06218479B1
公开(公告)日：2001-04-17
申请号：US09503628
申请日：2000-02-14
IPC分类号： C08L7504
CPC分类号： C08G18/664 , C08G18/08 , C08G18/0895 , C08G18/10 , C08L75/06 , C08G18/3206 , C08L75/04
摘要： This invention relates to thermoplastically processable, readily demouldable moulding compositions with low shrinkage and with a hardness of 65 to 85 Shore A, consisting of a mixture of A) a thermoplastic polyurethane of hardness 60 to 75 Shore A and B) a thermoplastic polyurethane of hardness 76 to 90 Shore A, which is produced continuously by a special multi-stage process.
摘要翻译： 本发明涉及具有低收缩率和硬度为65至85肖氏A的热塑性可加工的，易脱模的模塑组合物，由以下组成的混合物组成：A）硬度为60至75肖氏A的热塑性聚氨酯和B）硬度为76至 90 Shore A，通过特殊的多阶段过程连续生产。
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3.发明授权公开(公告)号：US06930163B2
公开(公告)日：2005-08-16
申请号：US09572225
申请日：2000-05-17
申请人： Wolfgang Bräuer , Wolfgang Kaufhold , Friedemann Müller , Jürgen Winkler , Herbert Heidingsfeld , Wolfgang Röhrig , Hans-Georg Hoppe
发明人： Wolfgang Bräuer , Wolfgang Kaufhold , Friedemann Müller , Jürgen Winkler , Herbert Heidingsfeld , Wolfgang Röhrig , Hans-Georg Hoppe
CPC分类号： C08G18/6607 , C08G18/0895
摘要： Process for the continuous preparation of thermoplastically processable polyurethane elastomers with improved softening properties is disclosed. The process is carried out in a tubular reactor at a ratio of the circumferential speed of the stirrer (in m/sec) in the tubular reactor and the throughput (in g/sec) of >0.03 m/g.
摘要翻译： 公开了连续制备具有改进的软化性能的热塑性加工性聚氨酯弹性体的方法。 该方法以管式反应器中搅拌器的圆周速度（m / sec）与通过量（g / sec）> 0.03m 2 / g的比例在管式反应器中进行。
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4.发明授权公开(公告)号：US06713145B2
公开(公告)日：2004-03-30
申请号：US10313563
申请日：2002-12-06
IPC分类号： B32B310
CPC分类号： B32B27/08 , B32B27/40 , B60J7/00 , E05D1/02 , E05Y2900/542 , F24S20/50 , F24S25/40 , F24S2030/16 , F24S2080/015 , Y02B10/20 , Y02E10/47 , Y02P80/24 , Y10T428/192 , Y10T428/195 , Y10T428/197 , Y10T428/24942 , Y10T428/26
摘要： The present invention is directed to transparent light-stable, movable composite systems which are composed of i) at least two rigid parts made of transparent, thermoplastic materials which are joined together by ii) at least one flexible connecting member made of transparent, light-stable thermoplastic polyurethane. The present invention is also directed to a process for preparing the transparent, light-stable movable composite systems of the present invention. Composite systems of the present invention are particularly useful in the building and construction industry. Upon being folded, composite systems of the present invention are very compact and, hence, easily transportable. In addition, composite systems of the present invention can be easily and reversibly folded or unfolded.
摘要翻译： 本发明涉及透明的光稳定的可移动复合材料系统，它们由以下组成：i）由透明的热塑性材料制成的至少两个刚性部件，它们通过由至少一个由透明的， 稳定的热塑性聚氨酯。 本发明还涉及一种制备本发明的透明，光稳定的可移动复合材料体系的方法。本发明的复合体系在建筑和建造业中特别有用。 在折叠时，本发明的复合系统非常紧凑，因此易于运输。 此外，本发明的复合系统可以容易且可逆地折叠或展开。
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5.发明授权Continuous preparation of melt-processable polyurethane in a twin screw extruder 有权在双螺杆挤出机中连续制备可熔融加工的聚氨酯公开(公告)号：US06294637B1
公开(公告)日：2001-09-25
申请号：US09141132
申请日：1998-08-27
IPC分类号： C08G1810
CPC分类号： C08G18/664 , C08G18/0895 , C08G18/10 , C08G2125/00 , C08G18/3203
摘要： The invention relates to a process for the continuous preparation of melt-processable polyurethanes, wherein an isocyanate-terminated prepolymer is intensively mixed with chain extender at temperatures of
摘要翻译： 本发明涉及一种用于连续制备可熔融加工的聚氨酯的方法，其中异氰酸酯封端的预聚物在<200℃的温度下与扩链剂强烈混合，并将得到的混合物转化为可熔融加工的聚氨酯 螺杆挤出机在准绝热反应条件下。
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公开(公告)号：US20110263678A1
公开(公告)日：2011-10-27
申请号：US13028035
申请日：2011-02-15
CPC分类号： C12N15/1138 , A61K38/00 , C07K14/71 , C12N2310/11
摘要： The present invention relates to the use of oligonucleotides for the preparation of a pharmaceutical composition for the prevention or treatment of a disease, wherein neurogenesis and/or neuroregeneration has a beneficial effect, in particular a disease like Morbus Alzheimer, Morbus Parkinson, Lewy Body Dementia,—Amyotrophic Lateral Sclerosis, Spinocerebellar Atrophies, Creutzfeldt Jakob Disease, Frontemporal Dementia, Morbus Pick, AIDS Dementia Complex, Vascular Dementia, Progressive Supranuclear Palsy, Corticobasal Degeneration, Multisystem-Atrophy, Hallervorden Spatz Disease, Huntington's disease, Stroke, Traumatic Brain and spinal cord Injury, Retinitis Pigmentosa, Macular Degeneration, Glaucoma, Cochlea Degeneration, Depression, Schizophrenia, Multiple Sclerosis, and developmental neurodegeneration.
摘要翻译： 本发明涉及寡核苷酸用于制备用于预防或治疗疾病的药物组合物的用途，其中神经发生和/或神经再生具有有益效果，特别是诸如Morbus阿尔茨海默氏症，Morbus帕金森氏病，路易体痴呆症 ，肌营养不良性侧索硬化症，脊髓小脑萎缩症，Creutzfeldt雅各布病，前痴呆症，Morbus Pick，艾滋病痴呆综合征，血管性痴呆，进行性核核性麻痹，皮质基底退化，多系统萎缩，Hallervorden Spatz病，亨廷顿氏病，中风，创伤性脑和脊髓 脐带损伤，视网膜色素变性，黄斑变性，青光眼，耳蜗变性，抑郁，精神分裂症，多发性硬化和发育性神经变性。
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公开(公告)号：US06664428B2
公开(公告)日：2003-12-16
申请号：US10204293
申请日：2002-08-20
申请人： Thomas Ostrowski , Kathrin Harre , Georg Heinrich Grosch , Gerd Höppner , Peter de Vocht , Dirk Leys , Jürgen Winkler , Stephan Bauer
发明人： Thomas Ostrowski , Kathrin Harre , Georg Heinrich Grosch , Gerd Höppner , Peter de Vocht , Dirk Leys , Jürgen Winkler , Stephan Bauer
IPC分类号： C07C4311
CPC分类号： C08G65/2696 , C08G65/2663
摘要： A process for the preparation of polyetherpolyols by reacting diols or polyols with ethylene oxide, propylene oxide, butylene oxide or a mixture thereof in the presence of a multimetal cyanide complex catalyst is proposed, the reaction being carried out in a stirred kettle reactor and the reaction mixture being circulated via an external heat exchanger by means of a pump.
摘要翻译： 提出了在多金属氰化物配合物催化剂存在下，通过二醇或多元醇与环氧乙烷，环氧丙烷，环氧丁烷或其混合物反应制备聚醚多元醇的方法，该反应在搅拌釜反应器中进行，反应 混合物通过泵通过外部热交换器循环。
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公开(公告)号：US06653441B2
公开(公告)日：2003-11-25
申请号：US10130846
申请日：2002-05-21
申请人： Kathrin Harre , Gerd Höppner , Georg Heinrich Grosch , Stephan Bauer , Jürgen Winkler , Els Paredis , Reinhard Lorenz , Inge Rotermund
发明人： Kathrin Harre , Gerd Höppner , Georg Heinrich Grosch , Stephan Bauer , Jürgen Winkler , Els Paredis , Reinhard Lorenz , Inge Rotermund
IPC分类号： C07C4311
CPC分类号： C08G65/2663 , C08G18/485 , C08G65/2696
摘要： In a process for preparing polyether alcohols by catalytic addition of at least two alkylene oxides onto H-functional initiator substances, at least one multimetal cyanide compound is used as catalyst and the addition of the alkylene oxides onto the initiator substance includes incorporation of at least one oxyalkylene block during whose formation at least two alkylene oxides are metered in together and the ratio of the alkylene oxides to one another in the mixture is changed during the joint introduction.
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公开(公告)号：US06563007B2
公开(公告)日：2003-05-13
申请号：US09915601
申请日：2001-07-26
申请人： Stefan Dinsch , Jürgen Winkler , Gottfried Knorr , Michael Reichelt , Gerd Höppner , Peter von Malotki
发明人： Stefan Dinsch , Jürgen Winkler , Gottfried Knorr , Michael Reichelt , Gerd Höppner , Peter von Malotki
IPC分类号： C07C2700
CPC分类号： C08G65/2606 , C08G65/2609 , Y10S521/914
摘要： Polyetherols based on solid initiator substances and liquid, hydroxyl-containing coinitiators are prepared by a catalyzed addition reaction of alkylene oxides by a process in which the initiator combination contains diols carrying ethoxy structures, the ratio of the average number of hydroxyl groups per mole of initiator combination to the number of ethoxy structures in the polyetherol being from 1:0.2 to 1:1.8 and the ratio of the amounts by weight of the diols carrying ethoxy structures to the average molecular weight of the polyetherol being from 1:2 to 1:15. The polyetherols prepared by this process are used for the preparation of PUR, in particular, rigid PUR foams.
摘要翻译： 基于固体引发剂物质和液体的含羟基的共聚引发剂的聚醚系通过环氧烷的催化加成反应制备，其中引发剂组合含有载有乙氧基结构的二醇，每摩尔引发剂的平均羟基比例 与聚乙烯醇中的乙氧基结构的数量的组合为1:0.2至1:1.8，并且负载乙氧基结构的二醇的重量比与聚己二酸酯的平均分子量的比例为1:2至1:15 。 通过该方法制备的聚醚酯用于制备PUR，特别是刚性PUR泡沫。
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公开(公告)号：US08022045B1
公开(公告)日：2011-09-20
申请号：US10597813
申请日：2005-02-09
CPC分类号： C12N15/1138 , A61K38/00 , C07K14/71 , C12N2310/11
摘要： The present invention relates to the use of oligonucleotides for the preparation of a pharmaceutical composition for the prevention or treatment of a disease, wherein neurogenesis and/or neuroregeneration has a beneficial effect, in particular a disease like Morbus Alzheimer, Morbus Parkinson, Lewy Body Dementia, Amyotrophic Lateral Sclerosis, Spinocerebellar Atrophies, Creutzfeldt Jakob Disease, Frontemporal Dementia, Morbus Pick, AIDS Dementia Complex, Vascular Dementia, Progressive Supranuclear Palsy, Corticobasal Degeneration, Multisystem-Atrophy, Hallervorden Spatz Disease, Huntington's disease, Stroke, Traumatic Brain and spinal cord Injury, Retinitis Pigmentosa, Macular Degeneration, Glaucoma, Cochlea Degeneration, Depression, Schizophrenia, Multiple Sclerosis, and developmental neurodegeneration.
摘要翻译： 本发明涉及寡核苷酸用于制备用于预防或治疗疾病的药物组合物的用途，其中神经发生和/或神经再生具有有益效果，特别是诸如Morbus阿尔茨海默氏症，Morbus帕金森氏病，路易体痴呆症 ，肌萎缩性侧索硬化症，脊髓小脑萎缩症，Creutzfeldt雅各布病，前痴呆症，Morbus拣选，艾滋病痴呆复合物，血管性痴呆，进行性核核麻痹，皮质基底变性，多系统萎缩，霍氏阴道病，亨廷顿病，中风，创伤性脑和脊髓 损伤，色素性视网膜炎，黄斑变性，青光眼，耳蜗变性，抑郁，精神分裂症，多发性硬化和发育性神经变性。
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