Star polymers, methods of preparation thereof, and uses thereof
    5.
    发明授权
    Star polymers, methods of preparation thereof, and uses thereof 有权
    星形聚合物,其制备方法及其用途

    公开(公告)号:US08765098B2

    公开(公告)日:2014-07-01

    申请号:US12750147

    申请日:2010-03-30

    IPC分类号: A61K49/00 A61K9/00

    摘要: A composition of matter comprising an amphiphilic star polymer, the star polymer comprising a crosslinked microgel core and 6 or more independent polymer arms covalently linked to the core, the 6 or more arms each comprising a hydrophilic polymer chain segment and a hydrophobic polymer chain segment; wherein each individual metal selected from the group consisting of beryllium, magnesium, calcium, strontium, barium, radium, aluminum, gallium, indium, thallium, germanium, tin, lead, arsenic, antimony, bismuth, tellurium, polonium, and metals of Groups 3 to 12 of the Periodic Table has a concentration in the star polymer of greater than or equal to 0 parts per million and less than or equal to 100 parts per million.

    摘要翻译: 包含两亲性星形聚合物的物质组合物,所述星形聚合物包含交联的微凝胶核心和共价连接到核心上的6个或更多个独立的聚合物臂,所述6个或更多个臂各自包含亲水性聚合物链段和疏水性聚合物链段; 其中选自组中的铍,镁,钙,锶,钡,镭,铝,镓,铟,铊,锗,锡,铅,砷,锑,铋,碲,onium onium和金属中的每种单独的金属 星形聚合物中的3至12的浓度大于或等于0ppm,小于或等于100ppm。

    Antimicrobial polymers and methods of manufacture thereof
    7.
    发明授权
    Antimicrobial polymers and methods of manufacture thereof 有权
    抗微生物聚合物及其制造方法

    公开(公告)号:US08361495B2

    公开(公告)日:2013-01-29

    申请号:US12646071

    申请日:2009-12-23

    摘要: Biodegradable cationic block copolymers are disclosed, comprising a hydrophilic block comprising first repeat units derived from a first cyclic carbonyl monomer by ring-opening polymerization, wherein more than 0% of the first repeat units comprise a side chain moiety comprising a quaternary amine group; a hydrophobic block comprising second repeat units derived from a second cyclic carbonyl monomer by ring-opening polymerization; an optional endcap group; and a chain fragment derived from an initiator for the ring opening polymerization. The cationic block copolymers form aqueous micelle mixtures suitable for antimicrobial applications.

    摘要翻译: 公开了可生物降解的阳离子嵌段共聚物,其包含亲水性嵌段,其包含通过开环聚合衍生自第一环状羰基单体的第一重复单元,其中多于0%的第一重复单元包含包含季胺基团的侧链部分; 疏水性嵌段,其包含通过开环聚合衍生自第二环状羰基单体的第二重复单元; 可选端帽组; 和衍生自用于开环聚合的引发剂的链片段。 阳离子嵌段共聚物形成适用于抗微生物应用的水性胶束混合物。

    METHODS OF RING OPENING POLYMERIZATION AND CATALYSTS THEREFOR
    10.
    发明申请
    METHODS OF RING OPENING POLYMERIZATION AND CATALYSTS THEREFOR 有权
    环形聚合方法及其催化剂

    公开(公告)号:US20120046437A1

    公开(公告)日:2012-02-23

    申请号:US12859336

    申请日:2010-08-19

    IPC分类号: C07D245/00 C08G63/08

    摘要: A salt catalyst comprises an ionic complex of i) a nitrogen base comprising one or more guanidine and/or amidine functional groups, and ii) an oxoacid comprising one or more active acid groups, the active acid groups independently comprising a carbonyl group (C═O), sulfoxide group (S═O), and/or a phosphonyl group (P═O) bonded to one or more active hydroxy groups; wherein a ratio of moles of the active hydroxy groups to moles of the guanidine and/or amidine functional groups is greater than 0 and less than 2.0. The salt catalysts are capable of catalyzing ring opening polymerization of cyclic carbonyl compounds.

    摘要翻译: 盐催化剂包含i)包含一个或多个胍和/或脒官能团的氮碱的离子络合物,和ii)包含一个或多个活性酸基团的含氧酸,所述活性酸基团独立地包含羰基(C = O),亚砜基(S = O)和/或与一个或多个活性羟基键合的膦酰基(P = O); 其中所述活性羟基的摩尔数与所述胍和/或脒官能团的摩尔数之比大于0且小于2.0。 盐催化剂能够催化环羰基化合物的开环聚合。