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公开(公告)号：US07217251B2
公开(公告)日：2007-05-15
申请号：US11112079
申请日：2005-04-22
IPC分类号： A61M1/00
CPC分类号： A61M25/00 , A61M5/14276 , A61M5/16813 , A61M27/006 , A61M2039/1005 , A61M2205/15 , A61M2206/16
摘要： Catheter systems including one or more flow restrictors are disclosed. The catheter systems may include two or more delivery branches. The delivery branches may be connected to a supply catheter section using a branching catheter connector that may include one or more flow restrictors. The flow restrictors may include a restrictor body located within a lumen with a channel located between the restrictor body and interior surface of the lumen, the channel restricting flow through the lumen past the flow restrictor. The channel may be defined by a groove formed in the restrictor body and/or the interior surface of the lumen. Methods of providing pressure relief by flowing fluid past a flow restrictor are also disclosed.
摘要翻译： 公开了包括一个或多个流量限制器的导管系统。 导管系统可以包括两个或更多个输送分支。 输送分支可以使用可包括一个或多个限流器的分支导管连接器连接到供应导管部分。 限流器可以包括位于管腔内的节流体，通道位于限流器主体和内腔内表面之间，通道限制流经管腔的流经限流器。 通道可以由形成在限流器主体中的凹槽和/或内腔的内表面限定。 还公开了通过使流体流过限流器来提供压力释放的方法。
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公开(公告)号：US07766860B2
公开(公告)日：2010-08-03
申请号：US11112077
申请日：2005-04-22
IPC分类号： A61M1/00
CPC分类号： A61M25/0021 , A61M5/14276 , A61M5/16813 , A61M25/00 , A61M25/0029 , A61M25/003 , A61M25/0043 , A61M25/0068 , A61M25/0071 , A61M25/0075 , A61M27/006 , A61M2025/0073 , A61M2039/1005 , A61M2205/15 , A61M2206/16
摘要： Catheter systems including one or more flow restrictors are disclosed. The catheter systems may include two or more delivery branches. The delivery branches may be connected to a supply catheter section using a branching catheter connector that may include one or more flow restrictors. The flow restrictors may include a restrictor body located within a lumen with a channel located between the restrictor body and interior surface of the lumen, the channel restricting flow through the lumen past the flow restrictor. The channel may be defined by a groove formed in the restrictor body and/or the interior surface of the lumen. Methods of providing pressure relief by flowing fluid past a flow restrictor are also disclosed.
摘要翻译： 公开了包括一个或多个流量限制器的导管系统。 导管系统可以包括两个或更多个输送分支。 输送分支可以使用可包括一个或多个限流器的分支导管连接器连接到供应导管部分。 限流器可以包括位于管腔内的节流体，通道位于限流器主体和内腔内表面之间，通道限制流经管腔的流经限流器。 通道可以由形成在限流器主体中的凹槽和/或内腔的内表面限定。 还公开了通过使流体流过限流器来提供压力释放的方法。
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公开(公告)号：US20100198184A1
公开(公告)日：2010-08-05
申请号：US12366165
申请日：2009-02-05
申请人： James M. Olsen , Michael Hegland , Dale F. Seeley
发明人： James M. Olsen , Michael Hegland , Dale F. Seeley
CPC分类号： A61M5/1486 , A61M5/1413 , A61M5/14248 , A61M5/152 , A61M2005/1587
摘要： A container for housing a fluid therapeutic composition includes a rigid housing, a collapsible bag and a seal. The housing has an opening and an interior surface. The interior surface forms a cavity having a volume. The bag is disposed in the housing and is expandable to contact the interior surface of the housing and occupy the entire volume of the cavity when filled with the fluid therapeutic composition. The bag has an opening that is fixed in proximity to the opening of the housing. The seal is configured to prevent air from entering the bag via the bag opening and to prevent air from entering the cavity of the housing via the housing opening.
摘要翻译： 用于容纳流体治疗组合物的容器包括刚性壳体，可折叠袋和密封件。 壳体具有开口和内表面。 内表面形成具有体积的空腔。 袋子设置在壳体中并且当被填充有流体治疗组合物时可扩张以接触壳体的内表面并占据空腔的整个体积。 袋子具有固定在壳体开口附近的开口。 密封件构造成防止空气经由袋开口进入袋中，并且防止空气经由壳体开口进入壳体的空腔。
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公开(公告)号：US20060173262A1
公开(公告)日：2006-08-03
申请号：US11343667
申请日：2006-01-31
申请人： Michael Hegland , Richard Stone
发明人： Michael Hegland , Richard Stone
IPC分类号： A61B5/04
CPC分类号： A61N1/0551 , A61B5/0422 , A61B2562/125 , B29C45/14639 , B29L2031/753 , Y10T29/49117 , Y10T29/49151 , Y10T29/49169 , Y10T29/49176 , Y10T29/49181 , Y10T29/49204 , Y10T29/4922
摘要： A medical lead having a conductor assembly and a segmented electrode assembly. The segmented electrode assembly includes a conductive segment electrically coupled to a conductor of the conductor assembly. A passageway is positioned between an inner surface and outer surface of the conductive segment. An electrically insulating material extends through the first passageway and into a gap adjacent the conductive segment. A segmented electrode assembly is also provided. The segmented electrode assembly includes a conductive segment having a passageway between an inner surface and outer surface of the conductive segment. An electrically insulating material extends through the passageway and into a gap adjacent the conductive segment.
摘要翻译： 具有导体组件和分段电极组件的医用引线。 分段电极组件包括电连接到导体组件的导体的导电部分。 通道位于导电段的内表面和外表面之间。 电绝缘材料延伸穿过第一通道并且延伸到与导电段相邻的间隙中。 还提供了分段电极组件。 分段电极组件包括具有在导电段的内表面和外表面之间的通路的导电段。 电绝缘材料延伸穿过通道并且延伸到与导电段相邻的间隙中。
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5.发明申请公开(公告)号：US20050106545A1
公开(公告)日：2005-05-19
申请号：US10957359
申请日：2004-10-01
申请人： Kenneth Heruth , Mark Lent , Michael Hegland
发明人： Kenneth Heruth , Mark Lent , Michael Hegland
摘要： An in-vitro model apparatus of a human spine and methods for detecting and analyzing substance distribution patterns therein. In one embodiment, the model apparatus includes a column body defining a passageway that substantially mimics the size, shape, and structure of an adult human spinal canal. Also included is a cord structure that may be located and anchored within the passageway. The cord structure substantially mimics the size, shape, and structure of an adult human spinal cord. For example, the cord structure may include connecting elements that resemble nerve roots, dentate ligaments, and the septum posticum of a human spine. The passageway of the model apparatus may be filled with a first fluid that simulates cerebro-spinal fluid (CSF), and a second fluid containing a drug (or simulated drug) may be introduced into the passageway, after which the drug's distribution within the passageway may be analyzed.
摘要翻译： 人体脊柱体外模型装置及其中物质分布模式的检测和分析方法。 在一个实施例中，模型设备包括定义通道的柱体，该通道基本上模拟成年人脊柱的尺寸，形状和结构。 还包括可以位于和锚定在通道内的绳索结构。 帘线结构基本上模仿成年人脊髓的尺寸，形状和结构。 例如，绳索结构可以包括类似神经根，齿状韧带和人脊柱的隔膜的连接元件。 模型装置的通道可以填充有模拟脑脊液（CSF）的第一流体，并且可以将含有药物（或模拟药物）的第二流体引入通道中，之后药物在通道内的分布 可以分析。
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公开(公告)号：US20110056076A1
公开(公告)日：2011-03-10
申请号：US12948592
申请日：2010-11-17
申请人： Michael Hegland , Richard T. Stone
发明人： Michael Hegland , Richard T. Stone
IPC分类号： H01R43/16
CPC分类号： A61N1/0551 , A61B5/0422 , A61B2562/125 , B29C45/14639 , B29L2031/753 , Y10T29/49117 , Y10T29/49151 , Y10T29/49169 , Y10T29/49176 , Y10T29/49181 , Y10T29/49204 , Y10T29/4922
摘要： A method of manufacturing a segmented electrode assembly. An electrically conducting tube is coupled to an electrically insulating material. The tube is generally cylindrical and hollow and defines one or more gaps at a first axial position. The tube also includes one or more bridges located at a second axial position. The method includes removing at least a portion of the bridge resulting in a segmented electrode assembly having at least one segment. A number embodiments of making a tube are also provided. In another embodiment a method of manufacturing a medical lead using a segmented electrode assembly is provided.
摘要翻译： 一种制造分段电极组件的方法。 导电管耦合到电绝缘材料。 管通常为圆柱形且中空并且在第一轴向位置限定一个或多个间隙。 管还包括位于第二轴向位置的一个或多个桥。 该方法包括去除桥的至少一部分，产生具有至少一个段的分段电极组件。 还提供了制造管的多个实施例。 在另一个实施例中，提供了使用分段电极组件制造医疗引线的方法。
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7.发明授权公开(公告)号：US07403883B2
公开(公告)日：2008-07-22
申请号：US10957359
申请日：2004-10-01
申请人： Kenneth T. Heruth , Mark S. Lent , Michael Hegland
发明人： Kenneth T. Heruth , Mark S. Lent , Michael Hegland
IPC分类号： G06G7/58
摘要： An in-vitro model apparatus of a human spine and methods for detecting and analyzing substance distribution patterns therein. In one embodiment, the model apparatus includes a column body defining a passageway that substantially mimics the size, shape, and structure of an adult human spinal canal. Also included is a cord structure that may be located and anchored within the passageway. The cord structure substantially mimics the size, shape, and structure of an adult human spinal cord. For example, the cord structure may include connecting elements that resemble nerve roots, dentate ligaments, and the septum posticum of a human spine. The passageway of the model apparatus may be filled with a first fluid that simulates cerebro-spinal fluid (CSF), and a second fluid containing a drug (or simulated drug) may be introduced into the passageway, after which the drug's distribution within the passageway may be analyzed.
摘要翻译： 人体脊柱体外模型装置及其中物质分布模式的检测和分析方法。 在一个实施例中，模型设备包括定义通道的柱体，该通道基本上模拟成年人脊柱的尺寸，形状和结构。 还包括可以位于和锚定在通道内的绳索结构。 帘线结构基本上模仿成年人脊髓的尺寸，形状和结构。 例如，绳索结构可以包括类似神经根，齿状韧带和人脊柱的隔膜的连接元件。 模型装置的通道可以填充有模拟脑脊液（CSF）的第一流体，并且可以将含有药物（或模拟药物）的第二流体引入通道中，之后药物在通道内的分布 可以分析。
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公开(公告)号：US20050143714A1
公开(公告)日：2005-06-30
申请号：US10950727
申请日：2004-09-27
申请人： Michael Hegland , James Olsen , James Skakoon
发明人： Michael Hegland , James Olsen , James Skakoon
IPC分类号： A61M5/142 , A61M39/10 , A61M39/12 , F16L37/084 , F16L37/098 , A61M25/16
CPC分类号： F16L37/0841 , A61M5/14276 , A61M39/1011 , A61M39/12 , A61M2039/1027 , A61M2039/1066 , A61M2205/583 , F16L37/0985
摘要： Sutureless pump connectors are discussed. The sutureless pump connectors include a restraint and a lock. The restraint has a proximal portion capable of engaging a portion of an implantable pump, such as a port. The restraint also has a distal portion capable of engaging a catheter. The lock is configured to secure the restraint to secured position relative to the pump and the catheter. The restraint may have a tab configured to secure the lock on the restraint. The tabs may be configured to releasably secure the lock.
摘要翻译： 讨论无缝线泵连接器。 无缝线泵连接器包括一个约束和一个锁。 约束具有能够接合可植入泵（例如端口）的一部分的近端部分。 约束还具有能够接合导管的远侧部分。 锁被构造成将约束固定到相对于泵和导管的固定位置。 约束可以具有构造成将锁固定在约束上的突出部。 突片可以被配置为可释放地固定锁。
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公开(公告)号：US08903504B2
公开(公告)日：2014-12-02
申请号：US13265077
申请日：2010-04-28
CPC分类号： A61N1/08 , A61B90/39 , A61B2090/3966 , A61N1/05 , A61N1/0551 , A61N1/086 , A61N1/3718 , A61N1/3752 , A61N2001/058 , A61N2001/0582 , A61N2001/086 , Y10T29/49016 , Y10T29/49117 , Y10T29/4921 , Y10T29/49227 , Y10T29/49826
摘要： Shields within implantable leads increase the torsional stiffness of the leads. The torsional stiffness may be reduced by cutting the shield axially to break the circumferential mechanical continuity of the shield. The circumferential shielding continuity of the shield may be re-established to preserve the shielding effect in various manners. The shield may overlap onto itself to close the slot created by the cut. A shield patch may be placed across the slot created by the cut. The shield may be located between two insulation layers of the lead. The shield may be cut and then the slot closed prior to application of the outer insulation layer. The outer insulation layer may then be added over the shield. The outer insulation layer may be compliant so that once covered, the circumferential mechanical continuity of the shield remains broken.
摘要翻译： 可植入引线内的护盾增加引线的扭转刚度。 可以通过轴向切割屏蔽来破坏屏蔽件的周向机械连续性来减小扭转刚度。 可以重新建立屏蔽件的圆周屏蔽连续性，以各种方式保持屏蔽效果。 屏蔽可能会重叠在自身上，以关闭由切割创建的槽。 屏蔽贴片可以放置在由切口产生的狭槽上。 屏蔽可以位于引线的两个绝缘层之间。 屏蔽可以被切割，然后在施加外绝缘层之前关闭槽。 然后可以将外部绝缘层添加到屏蔽上。 外绝缘层可以是柔性的，使得一旦被覆盖，屏蔽层的周向机械连续性保持断裂。
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10.发明申请公开(公告)号：US20120053664A1
公开(公告)日：2012-03-01
申请号：US13265077
申请日：2010-04-28
CPC分类号： A61N1/08 , A61B90/39 , A61B2090/3966 , A61N1/05 , A61N1/0551 , A61N1/086 , A61N1/3718 , A61N1/3752 , A61N2001/058 , A61N2001/0582 , A61N2001/086 , Y10T29/49016 , Y10T29/49117 , Y10T29/4921 , Y10T29/49227 , Y10T29/49826
摘要： Shields within implantable leads increase the torsional stiffness of the leads. The torsional stiffness may be reduced by cutting the shield axially to break the circumferential mechanical continuity of the shield. The circumferential shielding continuity of the shield may be re-established to preserve the shielding effect in various manners. The shield may overlap onto itself to close the slot created by the cut. A shield patch may be placed across the slot created by the cut. The shield may be located between two insulation layers of the lead. The shield may be cut and then the slot closed prior to application of the outer insulation layer. The outer insulation layer may then be added over the shield. The outer insulation layer may be compliant so that once covered, the circumferential mechanical continuity of the shield remains broken.
摘要翻译： 可植入引线内的护盾增加引线的扭转刚度。 可以通过轴向切割屏蔽来破坏屏蔽件的圆周机械连续性来减小扭转刚度。 可以重新建立屏蔽件的圆周屏蔽连续性，以各种方式保持屏蔽效果。 屏蔽可能会重叠在自身上，以关闭由切割创建的槽。 屏蔽贴片可以放置在由切口产生的狭槽上。 屏蔽可以位于引线的两个绝缘层之间。 屏蔽可以被切割，然后在施加外绝缘层之前关闭槽。 然后可以将外部绝缘层添加到屏蔽上。 外绝缘层可以是柔性的，使得一旦被覆盖，屏蔽层的周向机械连续性保持断裂。
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