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公开(公告)号：US10006891B2
公开(公告)日：2018-06-26
申请号：US12952495
申请日：2010-11-23
申请人： James Mitchell Wells , Mark Gregory , Matt Briscoe
发明人： James Mitchell Wells , Mark Gregory , Matt Briscoe
CPC分类号： G01N30/7206 , G01N30/20
摘要： Analytical instruments are provided that can include a sample inlet component with the sample inlet component including a first sampling port; a plurality of sample capturing assemblies; and a first valve assembly in fluid communication with both the sampling port and the sample capturing assemblies. The instrument can further include a sample analysis component in fluid communication with the first valve assembly of the sample inlet component; and an instrument control component in controlling communication with both the sample inlet component and the analysis component. Instrumental analysis methods are provided that can include continuously providing sample to at least one of a plurality of sample capturing assemblies; and selectively analyzing the contents of at least one of the plurality of sample capturing assemblies.
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2.发明申请公开(公告)号：US20110146381A1
公开(公告)日：2011-06-23
申请号：US12952495
申请日：2010-11-23
申请人： James Mitchell Wells , Mark Gregory , Matt Briscoe
发明人： James Mitchell Wells , Mark Gregory , Matt Briscoe
CPC分类号： G01N30/7206 , G01N30/20
摘要： Analytical instruments are provided that can include a sample inlet component with the sample inlet component including a first sampling port; a plurality of sample capturing assemblies; and a first valve assembly in fluid communication with both the sampling port and the sample capturing assemblies. The instrument can further include a sample analysis component in fluid communication with the first valve assembly of the sample inlet component; and an instrument control component in controlling communication with both the sample inlet component and the analysis component. Instrumental analysis methods are provided that can include continuously providing sample to at least one of a plurality of sample capturing assemblies; and selectively analyzing the contents of at least one of the plurality of sample capturing assemblies.
摘要翻译： 提供了分析仪器，其可以包括样品入口部件，样品入口部件包括第一取样口; 多个样本捕获组件; 以及与采样端口和样品捕获组件流体连通的第一阀组件。 仪器还可以包括与样品入口部件的第一阀组件流体连通的样品分析部件; 以及控制与样品入口部件和分析部件的通信的仪器控制部件。 提供了能够包括将样本连续提供给多个样本捕获组件中的至少一个的仪器分析方法; 并且选择性地分析所述多个样本捕获组件中的至少一个的内容物。
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公开(公告)号：US07582867B2
公开(公告)日：2009-09-01
申请号：US11906661
申请日：2007-10-03
IPC分类号： H01J49/42
CPC分类号： H01J49/424 , H01J49/4255
摘要： In one implementation, processes for designing mass separators from a series of mass separator electric field data and processes for designing an ion trap from a range of data pairs and a mass analyzer scale are provided. Methods for producing mass separators including ion traps having Z0/r0 ratios from about 0.84 to about 1.2 are also provided. Mass spectrometers are also provided that can include mass separators in tandem with one being an ion trap having a Z0/r0 ratio between 0.84 and 1.2. The present invention also provides methods for analyzing samples using mass separators having first and second sets of components defining a volume with a ratio of a distance from the center of the volume to a surface of the first component to a distance from the center of the volume to a surface of the second component being between 0.84 and 1.2.
摘要翻译： 在一个实施方案中，提供了用于从一系列质量分离器电场数据设计质量分离器的过程和用于从数据对和质量分析器量程范围设计离子阱的过程。 还提供了包括Z0 / r0比约为0.84至约1.2的离子阱的质量分离器的方法。 还提供质谱仪，其可以包括串联的质量分离器，一个是Z0 / r0比在0.84和1.2之间的离子阱。 本发明还提供了使用具有第一和第二组分量的质量分离器来分析样品的方法，所述第一组和第二组分量限定了从体积的中心到第一组分的表面到距离体积中心的距离的距离的比例的体积 到第二组分的表面在0.84和1.2之间。
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公开(公告)号：US08680461B2
公开(公告)日：2014-03-25
申请号：US11919323
申请日：2006-04-25
IPC分类号： H01J49/26
CPC分类号： H01J49/02 , H01J49/0031
摘要： A sample analysis apparatus (10) includes processing circuitry (22) coupled to a data set device (20) and a storage device (24) to acquire one data set from an analysis component (14) according to one analysis parameter set and to prepare another analysis parameter set using another previously acquired data set.
摘要翻译： 样本分析装置（10）包括耦合到数据集装置（20）的处理电路（22）和存储装置（24），以根据一个分析参数集从分析部件（14）获取一个数据集并准备 使用另一个先前获取的数据集的另一个分析参数集。
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5.发明授权Analysis methods, analysis device waveform generation methods, analysis devices, and articles of manufacture 有权分析方法，分析装置波形生成方法，分析装置和制品公开(公告)号：US08212206B2
公开(公告)日：2012-07-03
申请号：US10570707
申请日：2004-09-03
IPC分类号： B01D59/44
CPC分类号： H01J49/022 , H01J49/10 , H01J49/38
摘要： In one implementation, an analysis device operational method includes providing a plurality of levels of programming abstraction corresponding to programming of an analysis device configured to analyze a sample, receiving input data corresponding to one of the levels of programming abstraction, processing the input data to generate analysis control data, and implementing an operation with respect to analysis of the sample using the analysis control data.
摘要翻译： 在一个实现中，分析设备操作方法包括提供对应于被配置为分析样本的分析设备的编程的多个级别的编程抽象，接收对应于编程抽象级别之一的输入数据，处理输入数据以产生 分析控制数据，并且使用分析控制数据实现关于样品分析的操作。
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公开(公告)号：US20100154568A1
公开(公告)日：2010-06-24
申请号：US12621857
申请日：2009-11-19
IPC分类号： G01N1/20
CPC分类号： G01N1/08 , G01N1/2035 , G01N1/2247
摘要： Sample inlet components are provided that can include a skimmer associated with a conduit, with the skimmer defining an opening configured to receive at least some sample exiting the conduit. The conduit can have a first end extending to a second end, with the first end configured as an entrance for the sample and the second end configured as an exit for the sample. The second end of the conduit can include at least two portions, a first portion of the two portions being located physically closer to the skimmer than a second portion of the two portions. Sample introduction methods are provided that can include propelling sample from a conduit aligned with an opening of a skimmer. The majority of the sample can exit the conduit in a direction other than toward the opening of the skimmer.
摘要翻译： 提供了样品入口组件，其可以包括与管道相关联的撇渣器，撇渣器限定了被配置为接收离开管道的至少一些样品的开口。 导管可以具有延伸到第二端的第一端，其中第一端被配置为样品的入口，并且第二端被配置为样品的出口。 导管的第二端可以包括至少两个部分，两个部分的第一部分位于比两个部分的第二部分物理上更靠近撇渣器的位置。 提供了样品引入方法，其可以包括从与撇渣器的开口对准的导管推进样品。 大部分样品可以沿除了撇渣器开口以外的方向离开导管。
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公开(公告)号：US07294832B2
公开(公告)日：2007-11-13
申请号：US10537019
申请日：2003-12-02
IPC分类号： H01J49/42
CPC分类号： H01J49/424 , H01J49/4255
摘要： In one implementation, processes for designing mass separators from a series of mass separator electric field data and processes for designing an ion trap from a range of data pairs and a mass analyzer scale are provided. Methods for producing mass separators including ion traps having Z0/r0 ratios from about 0.84 to about 1.2 are also provided. Mass spectrometers are al provided that can include mass separators in tandem with one being an ion trap having a Zo/ro ratio between 0.84 and 1.2. The present invention also provides methods for analyzing samples using mass separators having first and second sets of components defining a volume with a ratio of a distance from the center of the volume to a surface of the first component to a distance from the center of the volume to a surface of the second component being between 0.84 and 1.2.
摘要翻译： 在一个实施方案中，提供了用于从一系列质量分离器电场数据设计质量分离器的过程和用于从数据对和质量分析器量程范围设计离子阱的过程。 还提供了用于生产包含离子阱的质量分离器的方法，所述离子阱具有约0.84至约1.2的Z 0/0/0比值。 还提供质谱仪，其可以包括串联的质量分离器，一个是离子阱，其具有0.84和1.2之间的Z / O / O比。 本发明还提供了使用具有第一和第二组分量的质量分离器来分析样品的方法，所述第一组和第二组分量限定了从体积的中心到第一组分的表面到距离体积中心的距离的距离的比例的体积 到第二组分的表面在0.84和1.2之间。
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公开(公告)号：US20100042334A1
公开(公告)日：2010-02-18
申请号：US11919323
申请日：2006-04-25
CPC分类号： H01J49/02 , H01J49/0031
摘要： Sample analysis apparatuses are disclosed that can include processing circuitry configured to acquire one data set from an analysis component configured according to one analysis parameter set, and prepare another analysis parameter set using another previously acquired data set. Sample analysis methods are also disclosed that can include acquiring first and second data sets from an analysis component and using the process and control component to process the first data set to prepare a second analysis component parameter set. Sample analysis instruments are disclosed that can include processing circuitry coupled to a storage device with the storage device including analysis component parameter sets associated with data parameter values with individual ones of the analysis component parameter sets being associated with individual ones of the data parameter values.
摘要翻译： 公开了可以包括处理电路的处理电路，该处理电路被配置为从根据一个分析参数组配置的分析部件获取一个数据集，并且使用另一个先前获取的数据集准备另一个分析参数集。 还公开了可以包括从分析组件获取第一和第二数据集并且使用过程和控制组件来处理第一数据集以准备第二分析组件参数集的样本分析方法。 公开了可以包括耦合到存储设备的处理电路的采样分析仪器，其中存储设备包括与数据参数值相关联的分析组件参数集，其中分析组件参数组中的各个与各个数据参数值相关联。
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公开(公告)号：US20080128605A1
公开(公告)日：2008-06-05
申请号：US11906661
申请日：2007-10-03
IPC分类号： H01J49/26
CPC分类号： H01J49/424 , H01J49/4255
摘要： In one implementation, processes for designing mass separators from a series of mass separator electric field data and processes for designing an ion trap from a range of data pairs and a mass analyzer scale are provided. Methods for producing mass separators including ion traps having Z0/r0 ratios from about 0.84 to about 1.2 are also provided. Mass spectrometers are also provided that can include mass separators in tandem with one being an ion trap having a Z0/r0 ratio between 0.84 and 1.2. The present invention also provides methods for analyzing samples using mass separators having first and second sets of components defining a volume with a ratio of a distance from the center of the volume to a surface of the first component to a distance from the center of the volume to a surface of the second component being between 0.84 and 1.2.
摘要翻译： 在一个实施方案中，提供了用于从一系列质量分离器电场数据设计质量分离器的过程和用于从数据对和质量分析器量程范围设计离子阱的过程。 还提供了用于生产包含离子阱的质量分离器的方法，所述离子阱具有约0.84至约1.2的Z 0/0/0比值。 还提供质谱仪，其可以包括串联的质量分离器，一个是离子阱，其具有0.84和1.2之间的Z 0/0/0/0比。 本发明还提供了使用具有第一和第二组分量的质量分离器来分析样品的方法，所述第一组和第二组分量限定了从体积的中心到第一组分的表面到距离体积中心的距离的距离的比例的体积 到第二组分的表面在0.84和1.2之间。
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公开(公告)号：US07064317B2
公开(公告)日：2006-06-20
申请号：US10485807
申请日：2002-08-12
IPC分类号： H01J49/00
CPC分类号： H01J49/424 , H01J49/0063 , H01J49/0072 , H01J49/0077 , H01J49/04 , H01J49/42
摘要： A method of inhibiting the reaction between ions of opposite polarity is disclosed. The method includes exposing a population of ions to a resonance excitation frequency during a mass-to-charge altering reaction between a first subpopulation of ions and a second subpopulation of ions, the resonance excitation frequency being tuned to inhibit the mass-to-charge altering reaction between an ion of the first subpopulation of ions having a predetermined mass-to-charge ratio and an ion of the second subpopulation of ions so that when an ion of the first subpopulation of ions attains the predetermined mass-to-charge ratio, the ion having the predetermined mass-to-charge ratio is selectively inhibited from reacting with ions of the second subpopulation of ions.
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