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公开(公告)号:US20120120635A1
公开(公告)日:2012-05-17
申请号:US13069288
申请日:2011-03-22
申请人: James Strong , Richard A. Tamburrino , John M. Ryan , Roger W. Leseberg , Ervin Goldfain , David M. Babson , David Stephens , Angelo Martellaro
发明人: James Strong , Richard A. Tamburrino , John M. Ryan , Roger W. Leseberg , Ervin Goldfain , David M. Babson , David Stephens , Angelo Martellaro
IPC分类号: F21V29/02 , F21L4/00 , F21V21/084
CPC分类号: F21V29/673 , A42B1/244 , A42B3/044 , A61B1/0684 , A61B1/0692 , A61B1/128 , A61B5/6814 , A61B90/30 , A61B90/35 , A61B90/53 , A61B2090/309 , A61B2090/502 , F21L4/00 , F21V5/008 , F21V11/10 , F21V13/12 , F21V21/084 , F21V23/003 , F21V29/61 , F21V29/70 , F21V31/03 , F21W2131/20 , F21W2131/205 , F21Y2115/10
摘要: Wearable headlight devices and related methods are provided and can include a luminaire that can include a housing having a luminaire vent therein for receiving cooling air and a light source contained within the housing. An air moving device can be located outside of the luminaire for facilitating cooling air intake through the luminaire vent. An exhaust tube can be connected to the luminaire and the air moving device to facilitate air flow of the cooling air between the luminaire and the air moving device.
摘要翻译: 提供了可佩戴的大灯装置和相关方法,并且可以包括可以包括其中具有用于接收冷却空气的灯具通风口的壳体和容纳在壳体内的光源的灯具。 空气移动装置可以位于照明器外部,以便于通过灯具通风口的冷却空气进入。 排气管可以连接到照明器和空气移动装置,以便于照明器和空气移动装置之间的冷却空气的空气流动。
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公开(公告)号:US08899774B2
公开(公告)日:2014-12-02
申请号:US13069288
申请日:2011-03-22
申请人: James Strong , Richard A. Tamburrino , John M. Ryan , Roger W. Leseberg , Ervin Goldfain , David M. Babson , David Stephens , Angelo Martellaro
发明人: James Strong , Richard A. Tamburrino , John M. Ryan , Roger W. Leseberg , Ervin Goldfain , David M. Babson , David Stephens , Angelo Martellaro
IPC分类号: F21V21/084 , A61B1/06 , A61B5/00 , A42B3/04 , F21W131/20 , A61B19/00
CPC分类号: F21V29/673 , A42B1/244 , A42B3/044 , A61B1/0684 , A61B1/0692 , A61B1/128 , A61B5/6814 , A61B90/30 , A61B90/35 , A61B90/53 , A61B2090/309 , A61B2090/502 , F21L4/00 , F21V5/008 , F21V11/10 , F21V13/12 , F21V21/084 , F21V23/003 , F21V29/61 , F21V29/70 , F21V31/03 , F21W2131/20 , F21W2131/205 , F21Y2115/10
摘要: Wearable headlight devices and related methods are provided and can include a luminaire that can include a housing having a luminaire vent therein for receiving cooling air and a light source contained within the housing. An air moving device can be located outside of the luminaire for facilitating cooling air intake through the luminaire vent. An exhaust tube can be connected to the luminaire and the air moving device to facilitate air flow of the cooling air between the luminaire and the air moving device.
摘要翻译: 提供了可佩戴的大灯装置和相关方法,并且可以包括可以包括其中具有用于接收冷却空气的灯具通风口的壳体和容纳在壳体内的光源的灯具。 空气移动装置可以位于照明器外部,以便于通过灯具通风口的冷却空气进入。 排气管可以连接到照明器和空气移动装置,以便于照明器和空气移动装置之间的冷却空气的空气流动。
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公开(公告)号:US08066985B2
公开(公告)日:2011-11-29
申请号:US12323223
申请日:2008-11-25
CPC分类号: A61K9/0019 , A61K35/765 , C12N2720/12032 , C12N2720/12232
摘要: Methods for treating proliferative disorders, by administering reovirus to a Ras-mediated proliferative disorder, are disclosed. The reovirus is administered so that it ultimately directly contacts ras-mediated proliferating cells. Proliferative disorders include but are not limited to neoplasms. Human reovirus, non-human mammalian reovirus, and/or avian reovirus can be used. If the reovirus is human reovirus, serotype 1 (e.g., strain Lang), serotype 2 (e.g., strain Jones), serotype 3 (e.g., strain Dearing or strain Abney), as well as other serotypes or strains of reovirus can be used. Combinations of more than one type and/or strain of reovirus can be used, as can reovirus from different species of animal. Either solid neoplasms or hematopoietic neoplasms can be treated.
摘要翻译: 公开了通过向Ras介导的增殖性病症施用呼肠孤病毒来治疗增殖性疾病的方法。 施用呼肠孤病毒使其最终直接接触ras介导的增殖细胞。 增生性疾病包括但不限于赘生物。 可以使用人呼肠病毒,非人哺乳动物呼肠病毒和/或禽呼肠孤病毒。 如果呼肠孤病毒是人呼肠病毒,则可以使用血清型1(例如,菌株Lang),血清型2(例如菌株琼斯),血清型3(例如,菌株Dearing或菌株Abney)以及呼肠孤病毒的其它血清型或菌株。 可以使用多于一种类型和/或菌株的呼肠病病毒的组合,以及来自不同动物种类的呼肠弧病毒。 可以治疗实体肿瘤或造血赘生物。
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公开(公告)号:US06576234B2
公开(公告)日:2003-06-10
申请号:US09852017
申请日:2001-05-10
IPC分类号: A01N6300
CPC分类号: C12N9/1205 , A61K35/765 , C12N7/00 , C12N2720/12232 , C12N2720/12261
摘要: Methods for treating neoplasia, by administering reovirus to a Ras-mediated neoplasm, and use of reovirus for manufacture of a medicament for the treatment of neoplasia, are disclosed. The reovirus is administered so that it ultimately directly contacts cells of the neoplasm. Human reovirus, non-human mammalian reovirus, and/or avian reovirus can be used. If the reovirus is human reovirus, type 1 (e.g., strain Lang), type 2 (e.g., strain Jones), type 3 (e.g., strain Dearing or strain Abney), as well as other sterotypes or strains of reovirus can be used. Combinations of more than one type and/or strain or reovirus can be used, as can reovirus from different species of animal. Either solid neoplasms or hematopoietic neoplasms can be treated.
摘要翻译: 公开了通过向Ras介导的肿瘤施用呼肠孤病毒和使用呼肠孤病毒来制造用于治疗肿瘤的药物的方法。 呼肠病毒的施用使其最终直接接触肿瘤细胞。 可以使用人呼肠病毒,非人哺乳动物呼肠病毒和/或禽呼肠孤病毒。 如果呼肠孤病毒是人呼肠病毒,可以使用1型(例如,菌株Lang),2型(例如菌株琼斯),3型(例如,菌株Dearing或菌株Abney)以及其它定向型或呼肠孤病毒菌株。 可以使用多于一种类型和/或菌株或呼肠孤病毒的组合,以及来自不同动物种的呼肠病毒。 可以治疗实体肿瘤或造血赘生物。
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公开(公告)号:US20110014155A1
公开(公告)日:2011-01-20
申请号:US12841550
申请日:2010-07-22
CPC分类号: A61K9/0019 , A61K35/765 , C12N2720/12032 , C12N2720/12232
摘要: Methods for treating proliferative disorders, by administering reovirus to a Ras-mediated proliferative disorder, are disclosed. The reovirus is administered so that it ultimately directly contacts ras-mediated proliferating cells. Proliferative disorders include but are not limited to neoplasms. Human reovirus, non-human mammalian reovirus, and/or avian reovirus can be used. If the reovirus is human reovirus, serotype 1 (e.g., strain Lang), serotype 2 (e.g., strain Jones), serotype 3 (e.g., strain Dearing or strain Abney), as well as other serotypes or strains of reovirus can be used. Combinations of more than one type and/or strain of reovirus can be used, as can reovirus from different species of animal. Either solid neoplasms or hematopoietic neoplasms can be treated.
摘要翻译: 公开了通过向Ras介导的增殖性病症施用呼肠孤病毒来治疗增殖性疾病的方法。 施用呼肠孤病毒使其最终直接接触ras介导的增殖细胞。 增生性疾病包括但不限于赘生物。 可以使用人呼肠病毒,非人哺乳动物呼肠病毒和/或禽呼肠孤病毒。 如果呼肠孤病毒是人呼肠病毒,则可以使用血清型1(例如,菌株Lang),血清型2(例如菌株琼斯),血清型3(例如,菌株Dearing或菌株Abney)以及呼肠孤病毒的其它血清型或菌株。 可以使用多于一种类型和/或菌株的呼肠病病毒的组合,以及来自不同动物种类的呼肠弧病毒。 可以治疗实体肿瘤或造血赘生物。
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公开(公告)号:US06455038B1
公开(公告)日:2002-09-24
申请号:US09594343
申请日:2000-06-15
IPC分类号: A61K3576
CPC分类号: A61K9/0019 , A61K35/765 , C12N2720/12032 , C12N2720/12232
摘要: Methods for treating proliferative disorders, by administering reovirus to a Ras-mediated proliferative disorder, are disclosed. The reovirus is administered so that it ultimately directly contacts ras-mediated proliferating cells. Proliferative disorders include but are not limited to neoplasms. Human reovirus, non-human mammalian reovirus, and/or avian reovirus can be used. If the reovirus is human reovirus, serotype 1 (e.g., strain Lang), serotype 2 (e.g., strain Jones), serotype 3 (e.g., strain Dearing or strain Abney), as well as other serotypes or strains of reovirus can be used. Combinations of more than one type and/or strain of reovirus can be used, as can reovirus from different species of animal. Either solid neoplasms or hematopoietic neoplasms can be treated.
摘要翻译: 公开了通过向Ras介导的增殖性病症施用呼肠孤病毒来治疗增殖性疾病的方法。 施用呼肠孤病毒使其最终直接接触ras介导的增殖细胞。 增生性疾病包括但不限于赘生物。 可以使用人呼肠病毒,非人哺乳动物呼肠病毒和/或禽呼肠孤病毒。 如果呼肠孤病毒是人呼肠病毒,则可以使用血清型1(例如,菌株Lang),血清型2(例如菌株琼斯),血清型3(例如,菌株Dearing或菌株Abney)以及呼肠孤病毒的其它血清型或菌株。 可以使用多于一种类型和/或菌株的呼肠病病毒的组合,以及来自不同动物种类的呼肠弧病毒。 可以治疗实体肿瘤或造血赘生物。
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公开(公告)号:US08071087B2
公开(公告)日:2011-12-06
申请号:US12841550
申请日:2010-07-22
CPC分类号: A61K9/0019 , A61K35/765 , C12N2720/12032 , C12N2720/12232
摘要: Methods for treating proliferative disorders, by administering reovirus to a Ras-mediated proliferative disorder, are disclosed. The reovirus is administered so that it ultimately directly contacts ras-mediated proliferating cells. Proliferative disorders include but are not limited to neoplasms. Human reovirus, non-human mammalian reovirus, and/or avian reovirus can be used. If the reovirus is human reovirus, serotype 1 (e.g., strain Lang), serotype 2 (e.g., strain Jones), serotype 3 (e.g., strain Dearing or strain Abney), as well as other serotypes or strains of reovirus can be used. Combinations of more than one type and/or strain of reovirus can be used, as can reovirus from different species of animal. Either solid neoplasms or hematopoietic neoplasms can be treated.
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公开(公告)号:US20090117082A1
公开(公告)日:2009-05-07
申请号:US12323223
申请日:2008-11-25
IPC分类号: A61K35/76
CPC分类号: A61K9/0019 , A61K35/765 , C12N2720/12032 , C12N2720/12232
摘要: Methods for treating proliferative disorders, by administering reovirus to a Ras-mediated proliferative disorder, are disclosed. The reovirus is administered so that it ultimately directly contacts ras-mediated proliferating cells. Proliferative disorders include but are not limited to neoplasms. Human reovirus, non-human mammalian reovirus, and/or avian reovirus can be used. If the reovirus is human reovirus, serotype 1 (e.g., strain Lang), serotype 2 (e.g., strain Jones), serotype 3 (e.g., strain Dearing or strain Abney), as well as other serotypes or strains of reovirus can be used. Combinations of more than one type and/or strain of reovirus can be used, as can reovirus from different species of animal. Either solid neoplasms or hematopoietic neoplasms can be treated.
摘要翻译: 公开了通过向Ras介导的增殖性病症施用呼肠孤病毒来治疗增殖性疾病的方法。 施用呼肠孤病毒使其最终直接接触ras介导的增殖细胞。 增生性疾病包括但不限于赘生物。 可以使用人呼肠病毒,非人哺乳动物呼肠病毒和/或禽呼肠孤病毒。 如果呼肠孤病毒是人呼肠病毒,则可以使用血清型1(例如,菌株Lang),血清型2(例如菌株琼斯),血清型3(例如,菌株Dearing或菌株Abney)以及呼肠孤病毒的其它血清型或菌株。 可以使用多于一种类型和/或菌株的呼肠病病毒的组合,以及来自不同动物种类的呼肠弧病毒。 可以治疗实体肿瘤或造血赘生物。
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公开(公告)号:US20090110665A1
公开(公告)日:2009-04-30
申请号:US12264072
申请日:2008-11-03
IPC分类号: A61K35/76
CPC分类号: C12N9/1205 , A61K35/765 , C12N7/00 , C12N2720/12232 , C12N2720/12261
摘要: Methods for treating neoplasia, by administering reovirus to a Ras-mediated neoplasm, are disclosed. The reovirus is administered so that it ultimately directly contacts cells of the neoplasm. Human reovirus, non-human mammalian reovirus, and/or avian reovirus can be used. If the reovirus is human reovirus, type 1 (e.g., strain Lang), type 2 (e.g., strain Jones), type 3 (e.g., strain Dearing or strain Abney), as well as other serotypes or strains of reovirus can be used. Combinations of more than one type and/or strain of reovirus can be used, as can reovirus from different species of animal. Either solid neoplasms or hematopoietic neoplasms can be treated.
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公开(公告)号:US20090098089A1
公开(公告)日:2009-04-16
申请号:US12252953
申请日:2008-10-16
CPC分类号: C12N9/1205 , A61K35/765 , C12N7/00 , C12N2720/12232 , C12N2720/12261
摘要: Methods for treating neoplasia, by administering reovirus to a Ras-mediated neoplasm, are disclosed. The reovirus is administered so that it ultimately directly contacts cells of the neoplasm. Human reovirus, non-human mammalian reovirus, and/or avian reovirus can be used. If the reovirus is human reovirus, type 1 (e.g., strain Lang), type 2 (e.g., strain Jones), type 3 (e.g., strain Dearing or strain Abney), as well as other serotypes or strains of reovirus can be used. Combinations of more than one type and/or strain of reovirus can be used, as can reovirus from different species of animal. Either solid neoplasms or hematopoietic neoplasms can be treated.
摘要翻译: 公开了通过向Ras介导的肿瘤施用呼肠孤病毒来治疗瘤形成的方法。 呼肠病毒的施用使其最终直接接触肿瘤细胞。 可以使用人呼肠病毒,非人哺乳动物呼肠病毒和/或禽呼肠孤病毒。 如果呼肠病毒是人呼肠病毒,可以使用类型1(例如,菌株Lang),2型(例如菌株琼斯),3型(例如,菌株Dearing或菌株Abney)以及其它呼肠孤病毒血清型或菌株。 可以使用多于一种类型和/或菌株的呼肠病病毒的组合,以及来自不同动物种类的呼肠弧病毒。 可以治疗实体肿瘤或造血赘生物。
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