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93 条记录 (耗时 0.076 秒)

    Device for adjusting a seat position of a bicycle seat
    2.
    发明授权
    Device for adjusting a seat position of a bicycle seat 有权

    公开(公告)号：US10450022B2

    公开(公告)日：2019-10-22

    申请号：US15885405

    申请日：2018-01-31

    申请人： David Watson

    发明人： David Watson

    IPC分类号： B62J1/08 ,  B62J1/28 ,  F16H25/22 ,  B62K23/02 ,  F15B15/14 ,  F15B15/20 ,  F15B1/26 ,  B62J99/00

    摘要： There is provided a device for adjusting a seat position of a bicycle seat. The device allows a rider of a bicycle to adjust the tilt of their bicycle seat while the bicycle is in motion, without the rider having to first dismount. In some embodiments, the rider may also adjust the height of their bicycle seat at substantially the same time as the seat's tilt is adjusted, again without the rider having to first dismount. There are described a motorized embodiment in which a motor is used to drive a tilt actuator and a height actuator, and a mechanized embodiment in which a source of pressurized air is used to drive the height actuator which in turn drives the tilt actuator.

    Building Method and Mould Units
    8.
    发明申请
    Building Method and Mould Units 审中-公开
    建筑方法和模具单元

    公开(公告)号：US20070251158A1

    公开(公告)日：2007-11-01

    申请号：US10579452

    申请日：2004-11-12

    申请人： David Watson

    发明人： David Watson

    IPC分类号： E04C1/39

    CPC分类号： E04B2/8629 ,  E04B2/26 ,  E04C1/397

    摘要： A mould unit is formed from injection molded plastics for economy and light weight. The mould unit is formed so that walls can quickly and accurately be assembled by stacking the units in courses. As the units are stacked, utilities are installed into ducts laid as required into the units. Doors, windows and other similar structures are formed into the walls as the units are stacked. When assembled, door and window frames may be fastened directly into the units and finishing board can be fastened to the inner or outer walls. When ducts, pipes and cables for utilities have been installed, the assembled walls are filled with a setting composition, such as foamed concrete.

    摘要翻译： 模具单元由注塑塑料形成，经济性和重量轻。 模具单元形成为使得壁可以通过将单元堆叠在一起而能够快速且准确地组装。 当单元堆叠时，公用设施安装到根据需要放置在单元中的管道中。 当堆叠单元时，门，窗和其他类似的结构形成在墙壁中。 组装后，门框和框架可以直接固定在单元中，整饰板可以固定在内墙或外墙上。 当安装了用于公用事业的管道，管道和电缆时，组装的墙壁上装有诸如泡沫混凝土的固定组合物。

    Campylobacter glycans and glycopeptides
    10.
    发明申请
    Campylobacter glycans and glycopeptides 有权
    弯曲杆菌聚糖和糖肽

    公开(公告)号：US20060165728A1

    公开(公告)日：2006-07-27

    申请号：US10523459

    申请日：2003-07-30

    申请人： Noel Young ,  Jean-Robert Brisson ,  John Kelly ,  David Watson ,  Christine Szymanski ,  Harold Jarrell

    发明人： Noel Young ,  Jean-Robert Brisson ,  John Kelly ,  David Watson ,  Christine Szymanski ,  Harold Jarrell

    IPC分类号： A61K39/02 ,  C08B37/00 ,  C07K14/205 ,  C12Q1/04

    CPC分类号： G01N33/56922 ,  A61K39/105 ,  C07H3/06 ,  G01N2400/02 ,  Y02A50/47

    摘要： Multiple strains and species of Campylobacter were found to share a common glycan moitie which is present in a plurality of surface-exposed glycoproteins. This glycan has the formula: GalNAc-a1,4-GalNAc-a1,4-[Glc-β1,3]GalNAc-a1,4-GalNAc-a1,4-GalNAc-a1,3-Bac, wherein Bac is 2,4-diacetamido-2,4,6-trideoxy-D-glucopyranose. This glycan and immunologically active fragments of it have use as vaccines against campylobacter infection in humans and animals. As well, antibodies which specifically bind these compounds may be provided. Such antibodies and vaccines may be used to prevent or neutralize campylobacter infections in livestock thereby preventing this pathogen from entering the human food chain. The glycan may be linked to one or more amino acids to form a glycopeptide. As well, a method for determining the glycan structure of an intact glycoprotein consists of subjecting a sample to high resolution magic angle spinning nuclear magnetic resonance (HR-MAS-NMR) spectroscopy.

    摘要翻译： 发现多种菌株和种类的弯曲杆菌分享一种常见的多糖表面暴露糖蛋白中存在的多糖异味。 该聚糖具有下式：GalNAc-a1,4-GalNAc-a1,4 [Glc-β1,3] GalNAc-a1,4-GalNAc-a1,4-GalNAc-a1,3-Bac，其中Bac为2， 4-二乙酰氨基-2,4,6-三脱氧-D-吡喃葡萄糖。 该聚糖及其免疫活性片段可用作针对人和动物中弯曲杆菌感染的疫苗。 同样，可以提供特异性结合这些化合物的抗体。 这样的抗体和疫苗可用于预防或中和家畜中的弯曲杆菌感染，从而防止该病原体进入人类食物链。 聚糖可以连接到一个或多个氨基酸以形成糖肽。 同样，确定完整糖蛋白的聚糖结构的方法包括使样品进行高分辨率魔角旋转核磁共振（HR-MAS-NMR）光谱。