Bar soap comprising pyrithione sources
    3.
    发明授权
    Bar soap comprising pyrithione sources 有权
    酒精皂包括吡啶硫酮源

    公开(公告)号:US08685908B2

    公开(公告)日:2014-04-01

    申请号:US13407252

    申请日:2012-02-28

    IPC分类号: A61K8/18

    摘要: A bar soap comprising a pyrithione source, a soap surfactant, and a pH adjusting agent selected from a group consisting of ammonia solution, triethanolamine, diethanolamine, monoethanolamine, potassium hydroxide, sodium hydroxide, soluble carbonate salts, and combinations thereof, wherein the bar soap attains a pH of greater than or equal to 10.7. A process of inhibiting the formation of a discoloration in a bar soap comprising pyrithione sources by adding pH adjusting agent to attain a pH of greater than or equal to 10.7. A process of inhibiting the formation of a discoloration in a bar soap caused by dissolved ferric ions and/or cupric ions and pyrithione sources in the bar, comprising the step of adding from about 0.3% to about 20% soluble carbonate salt during manufacturing of the bar soap.

    摘要翻译: 包含吡啶硫酮源,皂表面活性剂和选自氨溶液,三乙醇胺,二乙醇胺,单乙醇胺,氢氧化钾,氢氧化钠,可溶性碳酸盐及其组合的pH调节剂的条形皂,其中所述条皂 达到大于或等于10.7的pH。 通过添加pH调节剂以达到大于或等于10.7的pH来抑制包含吡啶硫酮源的条形皂的变色的方法。 一种抑制在酒吧中由溶解的铁离子和/或铜离子和吡啶硫酮源引起的皂条形成变色的方法,其包括在制造过程中加入约0.3%至约20%的可溶性碳酸盐的步骤 酒吧肥皂

    Bar Soap Comprising Pyrithione Sources
    4.
    发明申请
    Bar Soap Comprising Pyrithione Sources 有权
    酒皂包含吡硫酮源

    公开(公告)号:US20120220516A1

    公开(公告)日:2012-08-30

    申请号:US13407252

    申请日:2012-02-28

    IPC分类号: C11D9/60

    摘要: A bar soap comprising a pyrithione source, a soap surfactant, and a pH adjusting agent selected from a group consisting of ammonia solution, triethanolamine, diethanolamine, monoethanolamine, potassium hydroxide, sodium hydroxide, soluble carbonate salts, and combinations thereof, wherein the bar soap attains a pH of greater than or equal to 10.7. A process of inhibiting the formation of a discoloration in a bar soap comprising pyrithione sources by adding pH adjusting agent to attain a pH of greater than or equal to 10.7. A process of inhibiting the formation of a discoloration in a bar soap caused by dissolved ferric ions and/or cupric ions and pyrithione sources in the bar, comprising the step of adding from about 0.3% to about 20% soluble carbonate salt during manufacturing of the bar soap.

    摘要翻译: 包含吡啶硫酮源,皂表面活性剂和选自氨溶液,三乙醇胺,二乙醇胺,单乙醇胺,氢氧化钾,氢氧化钠,可溶性碳酸盐及其组合的pH调节剂的条形皂,其中所述条皂 达到大于或等于10.7的pH。 通过添加pH调节剂以达到大于或等于10.7的pH来抑制包含吡啶硫酮源的条形皂的变色的方法。 一种抑制在酒吧中由溶解的铁离子和/或铜离子和吡啶硫酮源引起的皂条形成变色的方法,其包括在制造过程中加入约0.3%至约20%的可溶性碳酸盐的步骤 酒吧肥皂

    METHOD AND SYSTEM FOR PRODUCING HIGH PURITY VANCOMYCIN HYDROCHLORIDE
    5.
    发明申请
    METHOD AND SYSTEM FOR PRODUCING HIGH PURITY VANCOMYCIN HYDROCHLORIDE 审中-公开
    生产高纯度VANCOMYCIN HYDROCHLORIDE的方法和系统

    公开(公告)号:US20170042817A1

    公开(公告)日:2017-02-16

    申请号:US15241863

    申请日:2016-08-19

    摘要: A method is provided for preparing spray dried powder containing vancomycin hydrochloride. The method comprises providing a vancomycin hydrochloride solution with a chromatographic purity of at least 95%, adding an excipient to the vancomycin hydrochloride solution to form a mixture solution of the vancomycin hydrochloride solution and the excipient, concentrating the mixed solution of the vancomycin hydrochloride solution and the excipient to form a 20% to 30% vancomycin concentrate, filtering the vancomycin concentrate to form a final filtrate, and spray drying the final filtrate to form a spray dried vancomycin hydrochloride powder with EP impurity B level of not more than 1.5%.

    摘要翻译: 提供了一种制备含有万古霉素盐酸盐的喷雾干燥粉末的方法。 该方法包括提供色谱纯度至少为95%的盐酸万古霉素溶液,向万古霉素盐酸盐溶液中加入赋形剂,形成盐酸万古霉素溶液和赋形剂的混合溶液,浓缩万古霉素盐酸盐溶液和 赋形剂形成20%至30%的万古霉素浓缩物,过滤万古霉素浓缩物以形成最终滤液,并喷雾干燥最终的滤液,形成喷雾干燥的盐酸万古霉素粉末,其中EP杂质B含量不超过1.5%。

    Method and system for producing high purity vancomycin hydrochloride
    6.
    发明授权
    Method and system for producing high purity vancomycin hydrochloride 有权
    生产高纯度万古霉素盐酸盐的方法和系统

    公开(公告)号:US09428291B2

    公开(公告)日:2016-08-30

    申请号:US14024131

    申请日:2013-09-11

    摘要: A method is provided for preparing spray dried powder containing vancomycin hydrochloride. The method comprises providing a vancomycin hydrochloride solution with a chromatographic purity of at least 95%, adding an excipient to the vancomycin hydrochloride solution to form a mixture solution of the vancomycin hydrochloride solution and the excipient, concentrating the mixed solution of the vancomycin hydrochloride solution and the excipient to form a 20% to 30% vancomycin concentrate, filtering the vancomycin concentrate to form a final filtrate, and spray drying the final filtrate to form a spray dried vancomycin hydrochloride powder with EP impurity B level of not more than 1.5%.

    摘要翻译: 提供了一种制备含有万古霉素盐酸盐的喷雾干燥粉末的方法。 该方法包括提供色谱纯度至少为95%的盐酸万古霉素溶液,向万古霉素盐酸溶液中加入赋形剂,形成盐酸万古霉素溶液和赋形剂的混合溶液,浓缩盐酸万古霉素溶液和 赋形剂形成20%至30%的万古霉素浓缩物,过滤万古霉素浓缩物以形成最终滤液,并喷雾干燥最终的滤液,形成喷雾干燥的盐酸万古霉素粉末,其中EP杂质B含量不超过1.5%。

    SYSTEM AND METHOD FOR DETERMINING A VEHICLE ROUTE
    10.
    发明申请
    SYSTEM AND METHOD FOR DETERMINING A VEHICLE ROUTE 有权
    用于确定车辆路线的系统和方法

    公开(公告)号:US20130261966A1

    公开(公告)日:2013-10-03

    申请号:US13438229

    申请日:2012-04-03

    IPC分类号: G01C21/00

    CPC分类号: G01C21/3469

    摘要: A method for determining a route for a vehicle includes receiving input indicative of a driver's dynamic control of the vehicle, determining the driver's driving style based on the input, and selecting values of parameters representing the driver's anticipated dynamic control of the vehicle based on the driving style. The method also includes identifying a plurality of candidate routes between an origin and destination, partitioning each of the candidate routes into a set of predefined route patterns, and determining an energy usage associated with each of the candidate routes based on the selected values and the set of predefined route patterns defining the candidate route. The method further includes identifying the candidate route having the minimum energy usage and providing output describing the route having the minimum energy usage.

    摘要翻译: 用于确定车辆的路线的方法包括接收表示驾驶员对车辆的动态控制的输入,基于输入确定驾驶员的驾驶风格,并且基于驾驶员选择表示驾驶员对车辆的预期动态控制的参数 样式。 该方法还包括识别原点和目的地之间的多个候选路由,将每个候选路由划分成一组预定义的路由模式,以及基于所选择的值和所述集合来确定与每个候选路由相关联的能量使用 定义候选路线的预定义路线模式。 该方法还包括识别具有最小能量使用的候选路线,并提供描述具有最小能量使用的路线的输出。