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68 条记录 (耗时 0.026 秒)

    9,10-Seco-steroid preparation
    1.
    发明授权
    9,10-Seco-steroid preparation 失效
    9,10-类固醇制剂

    公开(公告)号：US4045490A

    公开(公告)日：1977-08-30

    申请号：US651764

    申请日：1976-01-23

    申请人： Jean-Marie Cassal ,  Andor Furst ,  Werner Meier

    发明人： Jean-Marie Cassal ,  Andor Furst ,  Werner Meier

    IPC分类号： C07C401/00 ,  C07C49/76 ,  C07C49/82 ,  C07C49/84

    CPC分类号： C07C201/12 ,  C07C49/753 ,  C07C2102/24

    摘要： A process for the preparation of 9,10-seco-steroids of the formula ##STR1## wherein R.sup.1 and R.sup.2 independently are hydrogen, amino, OR.sup.5, OCOR.sup.6 or NHCOR.sup.5 wherein R.sup.5 is hydrogen or lower alkyl and R.sup.6 is lower alkyl or phenyl; R.sup.3 is lower alkyl; R.sup.4 is oxo, ##STR2## wherein R.sup.13 is lower alkyl, lower alkoxy - lower alkylene, tetrahydropyranyl or tetrahydrofuryl, R.sup.14 is lower alkyl or aryl and R.sup.15 and R.sup.16 are lower alkyl or taken together form lower alkylene or arylene, and n is 1 or 2 is disclosed. The 9,10-seco-steroids of this invention are useful intermediates for the preparation of steroids.

    摘要翻译： 其中R1和R2独立地是氢，氨基，OR5，OCOR6或NHCOR5，其中R5是氢或低级烷基，R6是低级烷基或苯基; R3是低级烷基; R4是氧代，其中R13是低级烷基，低级烷氧基 - 低级亚烷基，四氢吡喃基或四氢呋喃基，R14是低级烷基或芳基，R15和R16是低级烷基或一起形成低级亚烷基或亚芳基，n是1或 2。 本发明的9,10-秒类固醇是制备类固醇的有用中间体。

    9,10-Seco-steroids
    2.
    发明授权
    9,10-Seco-steroids 失效
    9,10-类固醇

    公开(公告)号：US4064173A

    公开(公告)日：1977-12-20

    申请号：US651763

    申请日：1976-01-23

    申请人： Jean-Marie Cassal ,  Andor Furst ,  Werner Meier

    发明人： Jean-Marie Cassal ,  Andor Furst ,  Werner Meier

    IPC分类号： C07C401/00 ,  C07C49/27

    CPC分类号： C07C205/45 ,  C07C2102/24

    摘要： A process for the preparation of 9,10-seco-steroids of the formula ##STR1## WHEREIN R.sup.1 and R.sup.2 independently are hydrogen, amino, OR.sup.5, OCOR.sup.6 or NHCOR.sup.5 wherein R.sup.5 is hydrogen or lower alkyl and R.sup.6 is lower alkyl or phenyl; R.sup.3 is lower alkyl; R.sup.4 is oxo, ##STR2## wherein R.sup.13 is lower alkyl, lower alkoxy -- lower alkylene, tetrahydropyranyl or tetrahydrofuryl, R.sup.14 is lower alkyl or aryl and R.sup.15 and R.sup.16 are lower alkyl or taken together form lower alkylene or arylene, and n is 1 or 2 is disclosed. The 9,10-seco-steroids of this invention are useful intermediates for the preparation of steroids.

    摘要翻译： 其中R 1和R 2独立地为氢，氨基，OR 5，OCOR 6或NHCOR 5，其中R 5为氢或低级烷基且R 6为低级烷基或苯基; R3是低级烷基; R4是氧代，其中R13是低级烷基，低级烷氧基 - 低级亚烷基，四氢吡喃基或四氢呋喃基，R14是低级烷基或芳基，R15和R16是低级烷基或一起形成低级亚烷基或亚芳基，n是1或 2。 本发明的9,10-秒类固醇是制备类固醇的有用中间体。

    Pregnane derivatives
    8.
    发明授权
    Pregnane derivatives 失效
    孕烯衍生物

    公开(公告)号：US4193921A

    公开(公告)日：1980-03-18

    申请号：US841430

    申请日：1977-10-12

    申请人： Andor Furst ,  Ludwig Labler ,  Werner Meier

    发明人： Andor Furst ,  Ludwig Labler ,  Werner Meier

    IPC分类号： C07J5/00 ,  C07J9/00 ,  C07J17/00 ,  C07J31/00 ,  C07J71/00

    CPC分类号： C07J31/006 ,  C07J17/00 ,  C07J71/001 ,  C07J9/00 ,  C07J9/005

    摘要： The present invention relates to pregnane derivatives of the formula ##STR1## wherein R.sup.1 and R.sup.3 are hydroxyl groups or readily cleavable etherified or esterified hydroxyl groups and R.sup.20 is hydroxymethyl or readily cleavable etherified or esterified hydroxy methyl, formyl, carboxyl or carbalkoxy useful as intermediates for the preparation of 1.alpha.-hydroxycholecalciferols. The present invention also relates to processes for the preparation of the pregnane derivatives and the intermediates thereof.

    摘要翻译： 本发明涉及式IMAGE的孕烷衍生物，其中R 1和R 3是羟基或易于切割的醚化或酯化的羟基，R 20是羟甲基或易裂解的醚化或酯化的羟甲基，甲酰基，羧基或烷氧羰基，可用作中间体 制备1α-羟基胆钙化醇。 本发明还涉及制备孕烷衍生物及其中间体的方法。

    LOWER NOZZLE FOR USE IN NUCLEAR FUEL ASSEMBLY
    10.
    发明申请
    LOWER NOZZLE FOR USE IN NUCLEAR FUEL ASSEMBLY 有权
    用于核燃料组件的低喷嘴

    公开(公告)号：US20140064428A1

    公开(公告)日：2014-03-06

    申请号：US13822516

    申请日：2012-05-11

    申请人： Dirk Blavius ,  Erhard Friedrich ,  Werner Meier

    发明人： Dirk Blavius ,  Erhard Friedrich ,  Werner Meier

    IPC分类号： G21C3/32

    CPC分类号： G21C3/3206 ,  G21C3/322 ,  G21C3/3305 ,  Y02E30/40

    摘要： A lower nozzle for use in a nuclear fuel assembly provided. The lower nozzle is of the type having an axis and comprising a transverse lower tie plate for channelling the coolant through the lower tie plate and a tubular skirt extending axially from the periphery of the lower tie plate, the skirt delimiting an axial housing closed at one end by the lower tie plate and open at the opposite end, a debris filter configured for axial insertion in the housing and snap-fit springs for retaining the debris filter in the housing after insertion. The springs are configured to shift the debris filter axially towards the lower tie plate.

    摘要翻译： 用于核燃料组件的下喷嘴。 下喷嘴是具有轴线的类型，并且包括用于将冷却剂引导通过下连接板的横向下连接板和从下连接板的周边轴向延伸的管状裙部，裙部限定在一个闭合的轴向壳体 通过下连接板结束并在相对端开口，构造成用于轴向插入壳体中的碎屑过滤器和用于在插入之后将碎屑过滤器保持在壳体中的卡合弹簧。 弹簧构造成将碎屑过滤器轴向移向下连接板。