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公开(公告)号：US6132760A
公开(公告)日：2000-10-17
申请号：US31619
申请日：1998-02-27
IPC分类号： A61K9/70 , A61K31/568 , A61K47/06 , A61K47/10 , A61K47/12 , A61K47/32 , A61P5/26 , A61F13/02 , A61F13/00
CPC分类号： A61K31/568 , A61K47/10 , A61K9/7053 , A61K9/7061
摘要： A transdermal delivery device including an adhesive layer that contains a therapeutically effective amount of testosterone and a delivery enhancing adjuvant comprising a terpene.
摘要翻译： 一种透皮递送装置，其包括含有治疗有效量的睾酮和包含萜烯的递送增强佐剂的粘合剂层。
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2.发明授权
公开(公告)号：US6019997A
公开(公告)日：2000-02-01
申请号：US781097
申请日：1997-01-09
CPC分类号： A61K47/10 , A61K47/14 , A61K47/26 , A61K9/0014 , Y10S514/937 , Y10S514/946 , Y10S514/947
摘要： Hydroalcoholic compositions useful for the enhancement of the transdermal delivery of a pharmaceutical agent, methods of preparation, transdermal delivery systems, and methods of delivering the pharmaceutical agent are provided. The composition includes a lower alcohol and water in a weight ratio of at least about 20:80, a pharmaceutical agent, and an emulsifier system.
摘要翻译： 提供了可用于增强药剂的透皮递送的水醇组合物，制备方法，透皮递送系统和递送药剂的方法。 组合物包含重量比为至少约20:80的低级醇和水，药剂和乳化剂体系。
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公开(公告)号：US09611572B2
公开(公告)日：2017-04-04
申请号：US13879182
申请日：2011-10-14
申请人： Eric M. Moore , John D. Stelter , Michael R. Berrigan , Francis E. Porbeni , Matthew T. Scholz , Korey W. Karls , Sian F. Fennessey , Scott J. Tuman , Cordell M. Hardy , Yifan Zhang
发明人： Eric M. Moore , John D. Stelter , Michael R. Berrigan , Francis E. Porbeni , Matthew T. Scholz , Korey W. Karls , Sian F. Fennessey , Scott J. Tuman , Cordell M. Hardy , Yifan Zhang
CPC分类号： D04H1/435 , D01F1/10 , D01F6/62 , D01F6/92 , D04H1/541 , Y10T442/608 , Y10T442/696
摘要： Dimensionally stable nonwoven fibrous webs include a plurality of fibers formed from one or more thermoplastic polyesters and an antishrink additive, preferably in an amount greater than 0% and no more than 10% by weight of the web. The webs have at least one dimension which decreases by no greater than 12% in the plane of the web when heated to a temperature above a glass transition temperature of the fibers. The webs may be used as wipes.
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公开(公告)号：US09572962B2
公开(公告)日：2017-02-21
申请号：US12936273
申请日：2009-04-01
申请人： Matthew T. Scholz
发明人： Matthew T. Scholz
CPC分类号： A61M27/00 , A61M1/0031 , A61M1/0088 , A61M2205/3334
摘要： Medical dressings and medical dressing kits that can be used to provide negative pressure wound therapy. The medical dressings include one or more normally-closed valves, and may include stand-off elements, barrier elements, closure elements, and septum elements. The medical dressing kits may further include pumps, fluid traps, and/or fittings.
摘要翻译： 可用于提供负压伤口治疗的医用敷料和医用敷料套件。 医疗敷料包括一个或多个常闭阀，并且可以包括间隔元件，阻挡元件，封闭元件和隔膜元件。 医疗敷料套件还可以包括泵，流体捕集器和/或配件。
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5.发明授权公开(公告)号：US09561134B2
公开(公告)日：2017-02-07
申请号：US14342572
申请日：2012-08-31
CPC分类号： A61F13/0216 , A61F13/00051 , A61F13/00063 , A61F13/0203 , A61F13/0226 , A61F13/023 , A61F2013/00174 , A61F2013/00285 , A61M35/00
摘要： Medical dressings and medical dressing kits that can be used to proved positive pressure wound therapy. The medical dressings include one or more normally-closed valves. The medical dressing kits may further include fittings.
摘要翻译： 可用于证实正压伤口治疗的医用敷料和医用敷料套件。 医用敷料包括一个或多个常闭阀。 医疗敷料套件还可以包括配件。
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公开(公告)号：US09555167B2
公开(公告)日：2017-01-31
申请号：US11609237
申请日：2006-12-11
申请人： Matthew J. Schmid , Ronald W. Ausen , Jay M. Jennen , Kelly S. Anderson , Matthew T. Scholz , Robert W. Peterson , Erin A. Satterwhite , Francis E. Porbeni
发明人： Matthew J. Schmid , Ronald W. Ausen , Jay M. Jennen , Kelly S. Anderson , Matthew T. Scholz , Robert W. Peterson , Erin A. Satterwhite , Francis E. Porbeni
CPC分类号： A61L31/16 , A01N25/10 , A61B46/00 , A61B2017/00889 , A61L29/06 , A61L29/16 , A61L31/06 , A61L2300/404 , A01N25/30 , A01N25/34 , A01N33/12 , A01N37/10 , A01N37/12 , C08L67/04
摘要： Antimicrobial compositions comprising aliphatic polyester, and an antimicrobial component effective for antimicrobial activity, and, in some embodiments, an enhancer. Example: blend of poly(lactic acid) polymer (55g) with propyleneglycol monolaurate antimicrobial component (9g), and benzoic acid enhancer (1g). Inventive resin compositions are effective against gram negative and gram positive bacteria, mold and mildew. Preferred compositions comprise materials that are GRAS (Generally Regarded As Safe).
摘要翻译： 包含脂族聚酯和对抗微生物活性有效的抗微生物组分的抗微生物组合物，在一些实施方案中为增强剂。 实施例：聚（乳酸）聚合物（55g）与丙二醇单月桂酸酯抗微生物成分（9g）和苯甲酸增强剂（1g）的共混。 本发明的树脂组合物对革兰氏阴性和革兰氏阳性菌，霉菌和霉菌均有效。 优选的组合物包括GRAS（通常被认为是安全的）的材料。
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公开(公告)号：US09277750B2
公开(公告)日：2016-03-08
申请号：US13185713
申请日：2011-07-19
申请人： Matthew T. Scholz , Danli Wang , Triet M. Lu , Dong-Wei Zhu
发明人： Matthew T. Scholz , Danli Wang , Triet M. Lu , Dong-Wei Zhu
CPC分类号： A61K31/79 , A01N59/12 , A61K47/12 , Y10S514/975 , A01N37/36 , A01N25/24 , A01N2300/00
摘要： A skin antisepsis composition comprising a comprising a (C1-4)alcohol and water in a ratio of at least 60:40, a hydroxycarboxylic acid, a cationic film-forming polymer, and at least one antimicrobial agent; and methods of using the composition are provided.
摘要翻译： 一种皮肤消毒组合物，其包含：（C 1-4）醇和至少60:40的比例的水，羟基羧酸，阳离子成膜聚合物和至少一种抗微生物剂; 并提供使用该组合物的方法。
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公开(公告)号：US20130211310A1
公开(公告)日：2013-08-15
申请号：US13881955
申请日：2011-10-28
申请人： G. Marco Bommarito , Matthew T. Scholz , Michael J. Svarovsky , Jeremy M. Yarwood , Scott M. Schnobrich , Robert J. DeVoe , Jun-Ying Zhang , Terry L. Smith
发明人： G. Marco Bommarito , Matthew T. Scholz , Michael J. Svarovsky , Jeremy M. Yarwood , Scott M. Schnobrich , Robert J. DeVoe , Jun-Ying Zhang , Terry L. Smith
CPC分类号： B08B17/06 , A61F13/00063 , B08B17/065 , Y10T428/24355
摘要： Disclosed are surfaces for resisting and reducing biofilm formation, particularly on medical articles (100). The surfaces include a plurality of microstructures (120) including a plurality of nanofeatures (140) arranged according to at least one unit cell. Also disclosed are methods for creating anti-adherent surfaces.
摘要翻译： 公开了用于抵抗和减少生物膜形成的表面，特别是在医疗用品（100）上。 表面包括多个微结构（120），其包括根据至少一个单元电池布置的多个纳米尺度（140）。 还公开了用于产生抗粘附表面的方法。
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9.发明申请PATIENT SUPPORT SYSTEMS AND METHODS FOR TRANSFERRING PATIENTS AND CONTROLLING PATIENT TEMPERATURE 有权患者支持系统和转移患者和控制患者温度的方法公开(公告)号：US20120304384A1
公开(公告)日：2012-12-06
申请号：US13577945
申请日：2011-02-25
CPC分类号： A61G7/1025 , A61F7/00 , A61F7/0097 , A61F2007/0001 , A61F2007/006 , A61G7/1021 , A61G7/1028 , A61G2203/90 , A61G2210/90
摘要： Patient support systems and methods for transferring patients and controlling patient temperature. The system can include a non-inflatable and self-supporting platform that can include a first surface and a second surface separated by a distance, a plurality of supporting structures that extends at least partially across the distance between the first surface and the second surface, a plenum, and a plurality of apertures formed through at least one of the first surface and the second surface and in fluid communication with the plenum. The system can further include a fluid source configured to move fluid into the plenum and out the plurality of apertures. A method of transferring a patient can include moving fluid into the plenum and out the plurality of apertures to form a fluid pallet. A method of controlling patient temperature can include moving a temperature-controlled fluid into the plenum and out the plurality of apertures.
摘要翻译： 患者支持系统和方法，用于转移患者和控制患者体温。 该系统可以包括不可充气和自支撑平台，该平台可以包括第一表面和第二表面，所述第一表面和第二表面被间隔一段距离;多个支撑结构，其至少部分延伸穿过第一表面和第二表面之间的距离， 一个通风室，以及通过第一表面和第二表面中的至少一个形成并与气室流体连通的多个孔。 该系统还可以包括被配置为将流体移动到通风室中并流出多个孔的流体源。 传送患者的方法可以包括将流体移动到通气室中并且从多个孔中排出以形成流体托盘。 控制患者体温的方法可以包括将温度控制的流体移动到通气室中并从多个孔中出来。
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公开(公告)号：US08173113B1
公开(公告)日：2012-05-08
申请号：US08855933
申请日：1997-05-14
IPC分类号： A61K31/74
CPC分类号： A61K9/7053 , A61K9/006 , A61L15/585 , C08L33/02
摘要： A bioadhesive composition that adheres suitably to a mucosal surface and is capable of delivering drugs in sustained fashion, and a patch comprising the bioadhesive composition. Methods of using and processes for preparing the bioadhesive composition are also described.
摘要翻译： 适合粘附到粘膜表面并能够以持续方式递送药物的生物粘合剂组合物和包含生物粘合剂组合物的贴剂。 还描述了制备生物粘合剂组合物的使用方法和方法。
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