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13 条记录 (耗时 0.025 秒)

    Radiation-curable prepolymers
    1.
    发明申请
    Radiation-curable prepolymers 有权

    公开(公告)号：US20060030679A1

    公开(公告)日：2006-02-09

    申请号：US11243928

    申请日：2005-10-05

    申请人： John Phelan ,  Michael Quinn ,  Joshua Wallach

    发明人： John Phelan ,  Michael Quinn ,  Joshua Wallach

    IPC分类号： C08G18/00

    CPC分类号： C08G18/672 ,  C08G18/678 ,  G02B1/043 ,  C08L75/04 ,  C08G18/6677

    摘要： The present invention provides a radiation-curable prepolymer. The radiation-curable prepolymer of the invention is prepared by reacting an isocyanate-capped polyurethane with an ethylenically unsaturated amine or an ethylenically unsaturated monohydroxy compound or a mixture thereof, wherein the isocyanate-capped polyurethane is a copolymerization production of: (a) at least one polyalkylene glycol; (b) at least one branching agent having at least three hydroxy groups; and (c) at least one di- or polyisocyanate. The radiation-curable prepolymer of the invention can find use in economically producing contact lenses which have durable, highly elastic soft contact lenses with desired physical properties. In addition, the present invention provides method for making a radiation-curable prepolymer of the invention and for making a medical device, preferably an ophthalmic device, more preferably a contact lens.

    Polymerizable materials
    2.
    发明申请
    Polymerizable materials 有权
    可聚合材料

    公开(公告)号：US20070149672A1

    公开(公告)日：2007-06-28

    申请号：US11704127

    申请日：2007-02-08

    申请人： Michael Quinn ,  Lawrence Chapoy ,  John Phelan

    发明人： Michael Quinn ,  Lawrence Chapoy ,  John Phelan

    IPC分类号： C08K3/38

    CPC分类号： G02B1/043 ,  C08L29/04 ,  C08L33/26 ,  C08L39/06 ,  C08L75/04 ,  C08L2666/04 ,  C08L2666/20

    摘要： The present invention provides a polymerizable material for making a polymeric article, the polymerizable material comprising: a water-soluble polyvinyl alcohol having crosslinkable groups; and a modifier in an amount sufficient to improve one or more physical properties of a polymeric article made from the polymerizable material, wherein the one or more physical properties are selected from the group consisting of stress at break (N/mm2), percentage of elongation at break, toughness or energy to break (N·mm), and susceptibility to fracture. The modifier is selected from the group consisting of nanoparticles having a hydrophilic surface, a copolymer having hydrophobic groups or units for imparting at least one desired physical property to said ophthalmic device and hydrophilic groups or units in an amount sufficient to render the copolymer miscible with the polyvinyl alcohol, and mixtures thereof. In addition, the present invention provides a polymeric article obtained by polymerization of a polymerizable material of the invention and also a method for modifying one or more physical properties of a hydrogel article obtained from the polymerization of a crosslinkable polymer.

    摘要翻译： 本发明提供了一种用于制造聚合物的可聚合材料，该可聚合材料包括：具有可交联基团的水溶性聚乙烯醇; 以及足以改善由可聚合材料制成的聚合物制品的一种或多种物理性能的量的改性剂，其中所述一种或多种物理性质选自断裂应力（N / mm 2 < / SUP>），断裂伸长百分比，韧性或断裂能（N.mm）和易破裂性。 改性剂选自具有亲水表面的纳米颗粒，具有疏水基团的共聚物或用于赋予所述眼科装置至少一种所需物理性能的单元和足以使共聚物与所述眼科装置混溶的亲水基团或单元 聚乙烯醇及其混合物。 此外，本发明提供了通过聚合本发明的可聚合材料获得的聚合物制品，以及用于改性由可交联聚合物的聚合获得的水凝胶制品的一种或多种物理性质的方法。

    Novel biocompatible inks, preparation, and uses thereof
    3.
    发明申请
    Novel biocompatible inks, preparation, and uses thereof 审中-公开
    新颖的生物相容性油墨，其制备及其用途

    公开(公告)号：US20080012164A1

    公开(公告)日：2008-01-17

    申请号：US11903172

    申请日：2007-09-20

    申请人： John Phelan ,  Michael Quinn

    发明人： John Phelan ,  Michael Quinn

    IPC分类号： B29D11/00 ,  B05D3/00

    CPC分类号： C09D11/36 ,  C09D11/101 ,  G02B1/043

    摘要： An aqueous ink comprising containing a colorant and a radiation-curable oligomer or polymer containing H-active groups bonded to the oligomer or polymer backbone, some or all of whose hydrogen atoms have been substituted by radicals of a N-hydroxyalkyl (meth)acrylamide. Methods for printing the inventive inks upon medical devices, such as contact lenses, are also disclosed.

    摘要翻译： 一种水性油墨，其包含含有着色剂和可辐射固化的低聚物或含有与低聚物或聚合物主链键合的H-活性基团的聚合物，其一部分或全部氢原子已被N-羟烷基（甲基）丙烯酰胺基团取代。 还公开了在诸如隐形眼镜的医疗装置上印刷本发明油墨的方法。

    Polymerizable materials
    5.
    发明申请
    Polymerizable materials 审中-公开
    可聚合材料

    公开(公告)号：US20050085585A1

    公开(公告)日：2005-04-21

    申请号：US10676173

    申请日：2003-10-01

    申请人： Michael Quinn ,  Lawrence Chapoy ,  John Phelan

    发明人： Michael Quinn ,  Lawrence Chapoy ,  John Phelan

    IPC分类号： C08J3/00 ,  G02B1/04

    CPC分类号： G02B1/043 ,  C08L29/04 ,  C08L33/26 ,  C08L39/06 ,  C08L75/04 ,  C08L2666/04 ,  C08L2666/20

    摘要： The present invention provides a polymerizable material for making a polymeric article, the polymerizable material comprising: a water-soluble polyvinyl alcohol having crosslinkable groups; and a modifier in an amount sufficient to improve one or more physical properties of a polymeric article made from the polymerizable material, wherein the one or more physical properties are selected from the group consisting of stress at break (N/mm2), percentage of elongation at break, toughness or energy to break (N·mm), and susceptibility to fracture. The modifier is selected from the group consisting of nanoparticles having a hydrophilic surface, a copolymer having hydrophobic groups or units for imparting at least one desired physical property to said ophthalmic device and hydrophilic groups or units in an amount sufficient to render the copolymer miscible with the polyvinyl alcohol, and mixtures thereof. In addition, the present invention provides a polymeric article obtained by polymerization of a polymerizable material of the invention and also a method for modifying one or more physical properties of a hydrogel article obtained from the polymerization of a crosslinkable polymer.

    摘要翻译： 本发明提供了一种用于制造聚合物的可聚合材料，该可聚合材料包括：具有可交联基团的水溶性聚乙烯醇; 以及足以改善由可聚合材料制成的聚合物制品的一种或多种物理性质的量的改性剂，其中所述一种或多种物理性质选自断裂应力（N / mm 2， / SUP>），断裂伸长百分比，韧性或断裂能（N.mm）和易破裂性。 改性剂选自具有亲水表面的纳米颗粒，具有疏水基团的共聚物或用于赋予所述眼科装置至少一种所需物理性能的单元和足以使共聚物与所述眼科装置混溶的亲水基团或单元 聚乙烯醇及其混合物。 此外，本发明提供了通过聚合本发明的可聚合材料获得的聚合物制品，以及用于改性由可交联聚合物的聚合获得的水凝胶制品的一种或多种物理性质的方法。

    Crosslinkable poly(oxyalkylene)-containing polyamide prepolymers
    9.
    发明申请
    Crosslinkable poly(oxyalkylene)-containing polyamide prepolymers 审中-公开
    可交联聚（氧化烯）的聚酰胺预聚物

    公开(公告)号：US20070244211A1

    公开(公告)日：2007-10-18

    申请号：US11284747

    申请日：2005-11-21

    申请人： John Phelan

    发明人： John Phelan

    IPC分类号： C08G69/26 ,  C08F2/00 ,  G02B1/04

    CPC分类号： G02B1/043 ,  C08G69/40 ,  C08G69/48 ,  C08L2203/02 ,  C08L77/00 ,  C08L51/08

    摘要： The present invention provides a water-soluble crosslinkable poly(oxyalkylene)-containing prepolymer. The crosslinkable poly(oxyalkylene)-containing copolymer prepolymer of the invention is prepared by reacting an amine-capped poly(oxyalkylene)-containing polyamide with a multifunctional compound having at least one ethylenically unsaturated group and a function group coreactive with the capping amine groups of the amine-capped poly(oxyalkylene)-containing polyamide. The amine-capped poly(oxyalkylene)-containing polyamide is a copolymerization production of a mixture comprising: (a) at least one poly(oxyalkylene)diamine, (b) optionally at least one organic di- or poly-amine, (c) at least one dicarboxyl derivative, (d) optionally at least one polycarboxyl derivative, and (e) a carbodiimide. The crosslinkable poly(oxyalkylene)-containing prepolymer of the invention can find use in economically producing contact lenses which have improved thermal stability. In addition, the present invention provides method for making a medical device, preferably an ophthalmic device, more preferably a contact lens.

    摘要翻译： 本发明提供了一种水溶性可交联聚（氧化烯）的预聚物。 本发明的可交联的聚氧化烯（氧化烯）共聚物预聚物是通过胺基封端的聚（氧化烯）聚酰胺与具有至少一个烯键式不饱和基团的多官能化合物和与封端胺基 含胺封端的聚（氧化烯）聚酰胺。 含胺封端的聚（氧化烯）聚酰胺是共混生产的混合物，其包含：（a）至少一种聚（氧化烯）二胺，（b）任选的至少一种有机二胺或多胺，（c） 至少一种二羧基衍生物，（d）任选的至少一种聚羧基衍生物，和（e）碳二亚胺。 本发明的可交联聚（氧化烯）预聚物可用于经济地生产具有改善的热稳定性的隐形眼镜。 此外，本发明提供了制造医疗装置，优选眼科装置，更优选隐形眼镜的方法。

    Silicone hydrogels
    10.
    发明申请
    Silicone hydrogels 有权
    硅胶水凝胶

    公开(公告)号：US20070037898A1

    公开(公告)日：2007-02-15

    申请号：US11500757

    申请日：2006-08-08

    申请人： John Phelan ,  Angelika Domschke ,  Marcia Ash

    发明人： John Phelan ,  Angelika Domschke ,  Marcia Ash

    IPC分类号： G02C7/04 ,  C08L83/04 ,  C08G77/04

    CPC分类号： G02B1/043 ,  C08L51/085

    摘要： The present invention provides silicone hydrogel materials having relatively high oxygen permeability and a relatively low modulus. The relatively-low modulus is achieved by adding a chain transfer agent into a polymerizable fluid composition in an amount sufficient to provide to the resultant silicone hydrogel material with a reduced modulus. In addition, the invention provides silicone hydrogel contact lenses comprising a silicone hydrogel material of the invention, a method for making a silicone hydrogel material of the invention, and a method for making a silicone hydrogel contact lens of the invention.

    摘要翻译： 本发明提供了具有相对较高的氧气渗透性和较低模量的硅酮水凝胶材料。 相对低的模量通过将链转移剂加入到可聚合流体组合物中来实现，其量足以提供具有降低的模量的所得硅酮水凝胶材料。 此外，本发明提供了包含本发明的硅氧烷水凝胶材料的硅酮水凝胶隐形眼镜，本发明的硅氧水凝胶材料的制备方法和本发明的硅氧水凝胶隐形眼镜的制备方法。