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公开(公告)号：US20060015184A1
公开(公告)日：2006-01-19
申请号：US11047982
申请日：2005-01-31
申请人： John Winterbottom , Ryan Belaney , David Knaack , Todd Boyce , Lawrence Shimp , Samuel Lee , David Kaes , Marc Burel
发明人： John Winterbottom , Ryan Belaney , David Knaack , Todd Boyce , Lawrence Shimp , Samuel Lee , David Kaes , Marc Burel
IPC分类号： A61F2/30
CPC分类号： A61L27/3608 , A61F2/28 , A61F2/3094 , A61F2/44 , A61F2/4455 , A61F2002/2817 , A61F2002/2835 , A61F2002/30062 , A61F2002/3008 , A61F2002/30092 , A61F2002/3023 , A61F2002/30261 , A61F2002/30387 , A61F2002/30405 , A61F2002/30426 , A61F2002/30433 , A61F2002/30448 , A61F2002/305 , A61F2002/3055 , A61F2002/30556 , A61F2002/30599 , A61F2002/30616 , A61F2002/30828 , A61F2002/30841 , A61F2002/3085 , A61F2002/30879 , A61F2002/30892 , A61F2002/30904 , A61F2002/4475 , A61F2210/0004 , A61F2210/0014 , A61F2220/0025 , A61F2220/0041 , A61F2220/005 , A61F2230/0069 , A61F2230/0082 , A61F2250/0009 , A61F2250/0063 , A61F2250/0098 , A61F2310/00017 , A61F2310/00023 , A61F2310/00029 , A61F2310/00179 , A61F2310/00359 , A61F2310/00365 , A61F2310/00377 , A61L27/3658 , A61L27/44 , A61L27/46 , A61L27/58 , A61L2430/38
摘要： An implant system for fusing vertebrae includes a variety of shapes that may be stacked to accommodate different intervertebral spacings and curvatures. The implants comprise polymer-bone composites that have osteogenic properties. By selection of an appropriate set of shapes, the surgeon can tailor the overall shape of the implant before or during surgery, in order to best match the shape of the intervertebral cavity for a particular patient.
摘要翻译： 用于融合椎骨的植入系统包括可以被堆叠以适应不同椎间间隙和曲率的各种形状。 植入物包含具有成骨性质的聚合物 - 骨复合材料。 通过选择适当的形状集，外科医生可以在手术之前或手术期间定制植入物的整体形状，以便最佳地匹配特定患者的椎间孔的形状。
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公开(公告)号：US20050251267A1
公开(公告)日：2005-11-10
申请号：US11047992
申请日：2005-01-31
申请人： John Winterbottom , Ryan Belaney , David Knaack , Todd Boyce , Lawrence Shimp , Samuel Lee , David Kaes
发明人： John Winterbottom , Ryan Belaney , David Knaack , Todd Boyce , Lawrence Shimp , Samuel Lee , David Kaes
CPC分类号： A61F2/28 , A61F2/4644 , A61F2002/30062 , A61F2002/3093 , A61F2002/4645 , A61F2210/0004 , A61F2310/00179
摘要： An implant including a cell conducting phase and a binder phase. At least a portion of the surface of the implant includes the cell conducting phase, and the cell conducting phase defines a path from the surface of the implant to an interior of the implant.
摘要翻译： 包括细胞传导相和粘结相的植入物。 植入物的表面的至少一部分包括细胞传导相，并且细胞传导相限定从植入物表面到植入物内部的路径。
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公开(公告)号：US20080069852A1
公开(公告)日：2008-03-20
申请号：US11625086
申请日：2007-01-19
CPC分类号： A61L27/56 , A61F2/28 , A61F2002/30062 , A61F2002/30677 , A61F2210/0004 , A61F2310/00293 , A61F2310/00359 , A61F2310/00365 , A61L27/446 , A61L27/46
摘要： The invention is directed toward porous composites for application to a bone defect site to promote new bone growth. The inventive porous composites comprise a biocompatible polymer and a plurality of particles of bone-derived material, inorganic material, bone substitute material or composite material. In certain embodiments, the porous composites are prepared using a method that includes a supercritical fluid (e.g., supercritical carbon dioxide) treatment. The invention also discloses methods of using these composites as bone void fillers.
摘要翻译： 本发明涉及用于骨缺损部位以促进新骨生长的多孔复合材料。 本发明的多孔复合材料包括生物相容性聚合物和多种骨源材料，无机材料，骨替代材料或复合材料的颗粒。 在某些实施方案中，使用包括超临界流体（例如超临界二氧化碳）处理的方法制备多孔复合材料。 本发明还公开了使用这些复合材料作为骨空隙填料的方法。
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公开(公告)号：US20120004594A1
公开(公告)日：2012-01-05
申请号：US13173701
申请日：2011-06-30
申请人： Olaf Schulz , James Howe , Rick Swaim , Bryan Huber , Joel Batts , David Harness , Ryan Belaney
发明人： Olaf Schulz , James Howe , Rick Swaim , Bryan Huber , Joel Batts , David Harness , Ryan Belaney
CPC分类号： A61B17/16 , A61B17/1659 , A61B17/1668 , A61B17/17 , A61B2217/005 , A61B2217/007 , A61L24/0042 , A61L24/02 , A61L27/12 , A61L27/58 , A61L2400/06 , A61L2430/02 , A61M1/0035 , A61M1/0058
摘要： Methods and articles of manufacture for treating patients with degenerative bone are provided. The methods are useful to improve bone quality in a localized area of a degenerative bone (e.g., osteopenic or osteoporotic bone), such as by improving BMD to be substantially similar to BMD in an average, healthy individual at the age of peak BMD. The methods can comprise forming a void in a localized area of the degenerative bone and filling the void with a bone regenerative material that causes generation of new, healthy, natural bone material. The articles of manufacture can comprise kits formed of various materials useful in the inventive methods for improving bone quality.
摘要翻译： 提供了治疗退行性骨患者的方法和制造方法。 这些方法可用于改善退行性骨（例如骨质疏松或骨质疏松性骨）的局部区域中的骨质量，例如通过将BMD改善为与BMD年龄基本相似的平均健康个体的BMD。 所述方法可以包括在退行性骨的局部区域中形成空隙并用引起新的，健康的天然骨材料的产生的骨再生材料填充空隙。 制品可以包括由可用于改善骨质量的本发明方法中的各种材料形成的套件。
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公开(公告)号：US09550010B2
公开(公告)日：2017-01-24
申请号：US13173701
申请日：2011-06-30
申请人： Olaf Schulz , James Howe , Rick Swaim , Bryan Huber , Joel Batts , David Harness , Ryan Belaney
发明人： Olaf Schulz , James Howe , Rick Swaim , Bryan Huber , Joel Batts , David Harness , Ryan Belaney
CPC分类号： A61B17/16 , A61B17/1659 , A61B17/1668 , A61B17/17 , A61B2217/005 , A61B2217/007 , A61L24/0042 , A61L24/02 , A61L27/12 , A61L27/58 , A61L2400/06 , A61L2430/02 , A61M1/0035 , A61M1/0058
摘要： Methods and articles of manufacture for treating patients with degenerative bone are provided. The methods are useful to improve bone quality in a localized area of a degenerative bone (e.g., osteopenic or osteoporotic bone), such as by improving BMD to be substantially similar to BMD in an average, healthy individual at the age of peak BMD. The methods can comprise forming a void in a localized area of the degenerative bone and filling the void with a bone regenerative material that causes generation of new, healthy, natural bone material. The articles of manufacture can comprise kits formed of various materials useful in the inventive methods for improving bone quality.
摘要翻译： 提供了治疗退行性骨患者的方法和制造方法。 这些方法可用于改善退行性骨（例如骨质疏松或骨质疏松性骨）的局部区域中的骨质量，例如通过将BMD改善为与BMD年龄基本相似的平均健康个体的BMD。 所述方法可以包括在退行性骨的局部区域中形成空隙并用引起新的，健康的天然骨材料的产生的骨再生材料填充空隙。 制品可以包括由可用于改善骨质量的本发明方法中的各种材料形成的套件。
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