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公开(公告)号：US5202242A
公开(公告)日：1993-04-13
申请号：US790287
申请日：1991-11-08
申请人： Jon S. Mynderse , James W. Martin , Jan R. Turner , Lawrence C. Creemer , Herbert A. Kirst , Mary C. Broughton , Mary L. B. Huber
发明人： Jon S. Mynderse , James W. Martin , Jan R. Turner , Lawrence C. Creemer , Herbert A. Kirst , Mary C. Broughton , Mary L. B. Huber
CPC分类号： C07H17/08 , A01N43/22 , C07D313/00 , C12N1/20 , C12P1/06 , C12P19/62 , Y10S435/822
摘要： New fermentation products A83543L, A83543M, and A83543N, N-demethyl derivatives thereof, and salts thereof, are useful for the control of insects. A83543PsaL1 is useful for the preparation of A83543 components. Methods for making A83543J, A83543L, A83543M, and A83543N by culture of Saccharopolyspora spinosa NRRL 18719 or NRRL 18720 are provided. Insecticidal and ectoparasiticidal compositions containing A83543L, A83543M, A83543N, and N-demethyl derivatives thereof are also provided.
摘要翻译： 新发酵产品A83543L，A83543M和A83543N，其N-去甲基衍生物及其盐可用于防治昆虫。 A83543PsaL1可用于制备A83543组分。 提供了通过培养酿酒孢子菌NRRL 18719或NRRL 18720制备A83543J，A83543L，A83543M和A83543N的方法。 还提供了含有A83543L，A83543M，A83543N和N-去甲基衍生物的杀虫剂和灭寄生组合物。
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公开(公告)号：US5670486A
公开(公告)日：1997-09-23
申请号：US483440
申请日：1995-06-07
申请人： Jon S. Mynderse , James A. Mabe , Jan R. Turner , Mary L. B. Huber , Mary C. Broughton , Walter M. Nakatsukasa , Lawrence Creemer , Herbert A. Kirst , James W. Martin
发明人： Jon S. Mynderse , James A. Mabe , Jan R. Turner , Mary L. B. Huber , Mary C. Broughton , Walter M. Nakatsukasa , Lawrence Creemer , Herbert A. Kirst , James W. Martin
CPC分类号： C07H17/08 , A01N43/22 , C12P19/62 , C12R1/01 , Y10S424/08 , Y10S424/10 , Y10S435/822
摘要： New A83543 components, including fermentation products A83543K, A83543O, A83543P, A83543U, A83543V, A83543W and A83543Y and N-demethyl derivatives, and salts thereof, are useful for the control of insects and mites. The pseudoaglycones of the new A83543 components are useful for the preparation of A83543 components. Methods are provided for making the new A83543 components by culturing of Saccharopolyspora spinosa NRRL 18395, NRRL 18537, NRRL 18538, or NRRL 18539, or NRRL 18743 or NRRL 18719 or NRRL 18823 in suitable culture medium. Insecticidal and ectoparasiticidal compositions containing new A83543 components are also provided.
摘要翻译： 包括发酵产物A83543K，A83543O，A83543P，A83543U，A83543V，A83543W和A83543Y和N-甲基衍生物及其盐的新A83543组分可用于防治昆虫和螨虫。 新的A83543组分的假脂肪酸可用于制备A83543组分。 提供了通过在合适的培养基中培养多孢孢杆菌NRRL 18395，NRRL 18537，NRRL 18538或NRRL 18539或NRRL 18743或NRRL 18719或NRRL 18823来制备新的A83543成分的方法。 还提供了含有新A83543组分的杀虫剂和灭寄生组合物。
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公开(公告)号：US5840861A
公开(公告)日：1998-11-24
申请号：US385497
申请日：1995-02-08
申请人： Jon S. Mynderse , Mary C. Broughton , Walter M. Nakatsukasa , James A. Mabe , Jan R. Turner , Lawrence Creemer , Mary L. B. Huber , Herbert A. Kirst , James W. Martin
发明人： Jon S. Mynderse , Mary C. Broughton , Walter M. Nakatsukasa , James A. Mabe , Jan R. Turner , Lawrence Creemer , Mary L. B. Huber , Herbert A. Kirst , James W. Martin
CPC分类号： C07H17/08 , A01N43/22 , C12P19/62 , C12R1/01 , Y10S424/08 , Y10S424/10 , Y10S435/822
摘要： New A83543 components, including fermentation products A83543K, A835430, A83543P, A83543U, A83543V, A83543W and A83543Y and N-demethyl derivatives, and salts thereof, are useful for the control of insects and mites. The pseudoaglycones of the new A83543 components are useful for the preparation of A83543 components. Methods are provided for making the new A83543 components by culturing of Saccharopolyspora spinosa NRRL 18395, NRRL 18537, NRRL 18538, or NRRL 18539, or NRRL 18743 or NRRL 18719 or NRRL 18823 in suitable culture medium. Insecticidal and ectoparasiticidal compositions containing new A83543 components are also provided.
摘要翻译： 包括发酵产物A83543K，A835430，A83543P，A83543U，A83543V，A83543W和A83543Y和N-甲基衍生物及其盐的新A83543组分可用于防治昆虫和螨虫。 新的A83543组分的假脂肪酸可用于制备A83543组分。 提供了通过在合适的培养基中培养多孢孢杆菌NRRL 18395，NRRL 18537，NRRL 18538或NRRL 18539或NRRL 18743或NRRL 18719或NRRL 18823来制备新的A83543成分的方法。 还提供了含有新A83543组分的杀虫剂和灭寄生组合物。
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公开(公告)号：US5670364A
公开(公告)日：1997-09-23
申请号：US474026
申请日：1995-06-07
申请人： Jon S. Mynderse , James A. Mabe , Jan R. Turner , Mary L. B. Huber , Mary C. Broughton , Walter M. Nakatsukasa , Lawrence Creemer , Herbert A. Kirst , James W. Martin
发明人： Jon S. Mynderse , James A. Mabe , Jan R. Turner , Mary L. B. Huber , Mary C. Broughton , Walter M. Nakatsukasa , Lawrence Creemer , Herbert A. Kirst , James W. Martin
CPC分类号： C07H17/08 , A01N43/22 , C12P19/62 , C12R1/01 , Y10S424/08 , Y10S424/10 , Y10S435/822
摘要： New A83543 components, including fermentation products A83543K, A835430, A83543P, A83543U, A83543V, A83543W and A83543Y and N-demethyl derivatives, and salts thereof, are useful for the control of insects and mites. The pseudoaglycones of the new A83543 components are useful for the preparation of A83543 components. Methods are provided for making the new A83543 components by culturing of Saccharopolyspora spinosa NRRL 18395, NRRL 18537, NRRL 18538, or NRRL 18539, or NRRL 18743 or NRRL 18719 or NRRL 18823 in suitable culture medium. Insecticidal and ectoparasiticidal compositions containing new A83543 components are also provided.
摘要翻译： 包括发酵产物A83543K，A835430，A83543P，A83543U，A83543V，A83543W和A83543Y和N-甲基衍生物及其盐的新A83543组分可用于防治昆虫和螨虫。 新的A83543组分的假脂肪酸可用于制备A83543组分。 提供了通过在合适的培养基中培养多孢子虫NRRL 18395，NRRL 18537，NRRL 18538或NRRL 18539或NRRL 18743或NRRL 18719或NRRL 18823来制备新的A83543成分的方法。 还提供了含有新A83543组分的杀虫剂和灭寄生组合物。
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5.发明授权Process for the production of A83543 compounds with Saccharopolyspora spinosa 失效生产具有Saccharopolyspora spinosa的A83543化合物的方法
公开(公告)号：US5591606A
公开(公告)日：1997-01-07
申请号：US397306
申请日：1995-03-02
CPC分类号： A01N43/22 , C07H17/08 , C12P19/62 , C12R1/01 , Y10S435/822
摘要： New A83543 components, including fermentation products A83543Q, A83543R, A83543S and A83543T and N-demethyl derivatives, and salts thereof, are useful for the control of insects and mites. The pseudoaglycones are useful for the preparation of A83543 components. Methods for making the new A83543 components by culture of Saccharopolyspora spinosa NRRL 18823 are provided. Insecticidal and ectoparasiticidal compositions containing new A83543 components are also provided.
摘要翻译： 新A83543组分，包括发酵产物A83543Q，A83543R，A83543S和A83543T和N-甲基衍生物及其盐可用于防治昆虫和螨虫。 假花粉可用于制备A83543组分。 提供了通过培养Saccharopolyspora spinosa NRRL 18823制备新的A83543组分的方法。 还提供了含有新A83543组分的杀虫剂和灭寄生组合物。
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公开(公告)号：US5539089A
公开(公告)日：1996-07-23
申请号：US301835
申请日：1994-09-07
IPC分类号： A01N43/22 , C07D313/00 , C07H17/08 , C12N1/20 , C12P1/06 , C12P19/62 , C07D305/00
摘要： A83543 Aglycones A83543AgA, A83543AgD, A83543AgE, and A83543AgF, and A83543 pseudoaglycones A83543PsaA2, A83543PsaB2, A83543PsaD2, and A83543PsaN2 are intermediates useful in preparation of known insecticides.
摘要翻译： A83543 Aglycones A83543AgA，A83543AgD，A83543AgE和A83543AgF以及A83543伪神经糖苷A83543PsaA2，A83543PsaB2，A83543PsaD2和A83543PsaN2是可用于制备已知杀虫剂的中间体。
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公开(公告)号：US5631155A
公开(公告)日：1997-05-20
申请号：US484462
申请日：1995-06-07
CPC分类号： A01N43/22 , C07H17/08 , C12P19/62 , C12R1/01 , Y10S435/822
摘要： New A83543 components, including fermentation products A83543Q, A83543R, A83543S and A83543T and N-demethyl derivatives, and salts thereof, are useful for the control of insects and mites. The pseudoaglycones are useful for the preparation of A83543 components. Methods for making the new A83543 components by culture of Saccharopolyspora spinosa NRRL 18823 are provided. Insecticidal and ectoparasiticidal compositions containing new A83543 components are also provided.
摘要翻译： 包括发酵产物A83543Q，A83543R，A83543S和A83543T和N-甲基衍生物及其盐的新A83543组分可用于防治昆虫和螨虫。 假花粉可用于制备A83543组分。 提供了通过培养Saccharopolyspora spinosa NRRL 18823制备新的A83543组分的方法。 还提供了含有新A83543组分的杀虫剂和灭寄生组合物。
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公开(公告)号：US5767253A
公开(公告)日：1998-06-16
申请号：US476159
申请日：1995-08-22
CPC分类号： A01N43/22 , C07H17/08 , C12P19/62 , C12R1/01 , Y10S435/822
摘要： New A83543 components, including fermentation products A83543Q, A83543R, A83543S and A83543T and N-demethyl derivatives, and salts thereof, are useful for the control of insects and mites. The pseudoaglycones are useful for the preparation of A83543 components. Methods for making the new A83543 components by culture of Saccharopolyspora spinosa NRRL 18823 are provided. Insecticidal and ectoparasiticidal compositions containing new A83543 components are also provided.
摘要翻译： 包括发酵产物A83543Q，A83543R，A83543S和A83543T和N-甲基衍生物及其盐的新A83543组分可用于防治昆虫和螨虫。 假花粉可用于制备A83543组分。 提供了通过培养Saccharopolyspora spinosa NRRL 18823制备新的A83543组分的方法。 还提供了含有新A83543组分的杀虫剂和灭寄生组合物。
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公开(公告)号：US4492693A
公开(公告)日：1985-01-08
申请号：US484129
申请日：1983-04-12
IPC分类号： A61K31/545 , A61K31/546 , A61P31/04 , C07D333/56 , C07D333/60 , C07D501/20 , C07D501/22 , C07D501/34 , C07D501/57 , C07D501/59
CPC分类号： C07D333/56 , C07D333/60
摘要： 7-(3-Benzothienyl)glycylamido cephalosporins have good gram positive activity and favorable pharmacokinetics and are orally effective.
摘要翻译： 7-（3-苯并噻吩基）甘氨酰胺基头孢菌素具有良好的革兰氏阳性活性和有利的药代动力学，且口服有效。
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公开(公告)号：US07015001B2
公开(公告)日：2006-03-21
申请号：US10329148
申请日：2002-12-23
申请人： Richard H. Baltz , M. Christine Broughton , Kathryn P. Crawford , Krishnamurthy Madduri , Donald J. Merlo , Patti J. Treadway , Jan R. Turner , Clive Waldron
发明人： Richard H. Baltz , M. Christine Broughton , Kathryn P. Crawford , Krishnamurthy Madduri , Donald J. Merlo , Patti J. Treadway , Jan R. Turner , Clive Waldron
IPC分类号： C12Q1/68
CPC分类号： C12N15/52 , C07K14/195 , C12P19/62
摘要： Spinosyn biosynthetic genes from Saccharopolyspora spinosa, spinosyn producing microorganisms transformed with the biosynthetic genes, methods using the biosynthetic genes to increase production of spinosyn insecticidal macrolides, and methods using the genes or fragments thereof to change the products produced by spinosyn-producing microorganisms are provided.
摘要翻译： 提供了来自酿酒酵母的Spinosyn生物合成基因，用生物合成基因转化的多杀菌素生成微生物，使用生物合成基因增加多杀菌素杀虫大环内酯的产生的方法，以及使用其基因或片段改变由产梭菌产生的微生物产生的产物的方法。
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