公开(公告)号：US06673090B2

公开(公告)日：2004-01-06

申请号：US09766940

申请日：2001-01-22

申请人： Jonathan D. Root ,  Kevin Hahnen ,  Tracy D. Maahs

发明人： Jonathan D. Root ,  Kevin Hahnen ,  Tracy D. Maahs

IPC分类号： A61M2900

CPC分类号： A61B18/24 ,  A61B18/02 ,  A61B18/1492 ,  A61B18/18 ,  A61B2017/00243 ,  A61B2018/00214

摘要： An ablation catheter system for capturing and removing necrotic tissue and thrombi generated during an ablative procedure is disclosed. The catheter typically includes an elongate member, a filtration assembly disposed within the distal region, and an ablation instrument at the distal end. Alternatively, the ablation instrument is carried on the distal end of an ablation catheter, which is disposed within a lumen of the catheter system. The catheter may further include an aspiration port and lumen. Methods of using the devices in preventing distal embolization during ablative procedures are disclosed.

摘要翻译： 公开了一种用于捕获和去除消融过程中产生的坏死组织和血栓的消融导管系统。 导管通常包括细长构件，设置在远端区域内的过滤组件和远端处的消融器械。 或者，消融器械被承载在消融导管的远端，消融导管设置在导管系统的内腔内。 该导管还可以包括抽吸端口和内腔。 公开了在烧蚀过程中使用该装置防止远端栓塞的方法。

公开(公告)号：US07326226B2

公开(公告)日：2008-02-05

申请号：US10699727

申请日：2003-11-03

申请人： Jonathan D. Root ,  Kevin Hahnen ,  Tracy D. Maahs

发明人： Jonathan D. Root ,  Kevin Hahnen ,  Tracy D. Maahs

IPC分类号： A61M29/00

CPC分类号： A61B18/24 ,  A61B18/02 ,  A61B18/1492 ,  A61B18/18 ,  A61B2017/00243 ,  A61B2018/00214

摘要： An ablation catheter system for capturing and removing necrotic tissue and thrombi generated during an ablative procedure is disclosed. The catheter typically includes an elongate member, a filtration assembly disposed within the distal region, and an ablation instrument at the distal end. Alternatively, the ablation instrument is carried on the distal end of an ablation catheter, which is disposed within a lumen of the catheter system. The catheter may further include an aspiration port and lumen. Methods of using the devices in preventing distal embolization during ablative procedures are disclosed.

摘要翻译： 公开了一种用于捕获和去除消融过程中产生的坏死组织和血栓的消融导管系统。 导管通常包括细长构件，设置在远端区域内的过滤组件和远端处的消融器械。 或者，消融器械被承载在消融导管的远端，消融导管设置在导管系统的内腔内。 该导管还可以包括抽吸端口和内腔。 公开了在烧蚀过程中使用该装置防止远端栓塞的方法。

公开(公告)号：US06235044B1

公开(公告)日：2001-05-22

申请号：US09369060

申请日：1999-08-04

申请人： Jonathan D. Root ,  Kevin Hahnen ,  Tracy D. Maahs

发明人： Jonathan D. Root ,  Kevin Hahnen ,  Tracy D. Maahs

IPC分类号： A61B1722

CPC分类号： A61B18/24 ,  A61B18/02 ,  A61B18/1492 ,  A61B18/18 ,  A61B2017/00243 ,  A61B2018/00214

摘要： An ablation catheter system for capturing and removing necrotic tissue and thrombi generated during an ablative procedure is disclosed. The catheter typically includes an elongate member, a filtration assembly disposed within the distal region, and an ablation instrument at the distal end. Alternatively, the ablation instrument is carried on the distal end of an ablation catheter, which is disposed within a lumen of the catheter system. The catheter may further include an aspiration port and lumen. Methods of using the devices in preventing distal embolization during ablative procedures are disclosed.

摘要翻译： 公开了一种用于捕获和去除消融过程中产生的坏死组织和血栓的消融导管系统。 导管通常包括细长构件，设置在远端区域内的过滤组件和远端处的消融器械。 或者，消融器械被承载在消融导管的远端上，消融导管设置在导管系统的内腔内。 该导管还可以包括抽吸端口和内腔。 公开了在烧蚀过程中使用该装置防止远端栓塞的方法。

公开(公告)号：US06592546B1

公开(公告)日：2003-07-15

申请号：US09016714

申请日：1998-01-30

申请人： Denise Barbut ,  Jonathan D. Root ,  Giovanni Pastrone ,  Tracy D. Maahs ,  Ross S. Tsugita

发明人： Denise Barbut ,  Jonathan D. Root ,  Giovanni Pastrone ,  Tracy D. Maahs ,  Ross S. Tsugita

IPC分类号： A61M2900

CPC分类号： A61F2/013 ,  A61B17/12022 ,  A61B17/12109 ,  A61B17/12136 ,  A61B17/12172 ,  A61B2017/00243 ,  A61F2/01 ,  A61F2002/018 ,  A61F2230/0006 ,  A61F2230/0065 ,  A61F2230/0067 ,  A61F2250/0003 ,  A61M2025/0073 ,  A61M2025/1052 ,  A61M2210/127

摘要： A balloon arterial cannula and methods for filtering blood. The devices generally include a mesh for filtering blood flowing within a blood vessel, particularly within an artery such as the aorta, a structure adapted to open and close the mesh within the blood vessel, a means to actuate the structure, and a balloon occluder which typically includes a flexible material enclosing a chamber. The methods generally include the steps of introducing a mesh into a blood vessel to capture embolic material, adjusting the mesh, if necessary, during the course of filtration, inflating the balloon occluder to occlude the vessel upstream of the mesh, and thereafter deflating the balloon occluder and removing the mesh and the captured foreign matter from the blood vessel. Additionally, visualization techniques are used to ensure effective filtration.

摘要翻译： 气囊动脉插管和血液过滤方法。 这些装置通常包括用于过滤血管内的血液的网格，特别是在诸如主动脉的动脉内，适于打开和关闭血管内的网状物的结构，致动结构的装置和气囊封堵器 通常包括围绕室的柔性材料。 所述方法通常包括以下步骤：将网状物引入血管以捕获栓塞材料，如果需要，在过滤过程中调整网孔，使球囊封堵器膨胀以封闭网孔上游的容器，然后使气囊放气 闭塞器并从血管中除去网状物和捕获的异物。 此外，可视化技术用于确保有效的过滤。

公开(公告)号：US07306575B2

公开(公告)日：2007-12-11

申请号：US10619760

申请日：2003-07-14

申请人： Denise Barbut ,  Jonathan D. Root ,  Giovanni Pastrone ,  Tracy D. Maahs ,  Ross S. Tsugita

发明人： Denise Barbut ,  Jonathan D. Root ,  Giovanni Pastrone ,  Tracy D. Maahs ,  Ross S. Tsugita

IPC分类号： A61M29/00

CPC分类号： A61F2/013 ,  A61B17/12022 ,  A61B17/12109 ,  A61B17/12136 ,  A61B17/12172 ,  A61B2017/00243 ,  A61F2/01 ,  A61F2002/018 ,  A61F2230/0006 ,  A61F2230/0065 ,  A61F2230/0067 ,  A61F2250/0003 ,  A61M2025/0073 ,  A61M2025/1052 ,  A61M2210/127

摘要： A balloon arterial cannula and methods for filtering blood. The devices generally include a mesh for filtering blood flowing within a blood vessel, particularly within an artery such as the aorta, a structure adapted to open and close the mesh within the blood vessel, a means to actuate the structure, and a balloon occluder which typically includes a flexible material enclosing a chamber. The methods generally include the steps of introducing a mesh into a blood vessel to capture embolic material, adjusting the mesh, if necessary, during the course of filtration, inflating the balloon occluder to occlude the vessel upstream of the mesh, and thereafter deflating the balloon occluder and removing the mesh and the captured foreign matter from the blood vessel. Additionally, visualization techniques are used to ensure effective filtration.

摘要翻译： 气囊动脉插管和血液过滤方法。 这些装置通常包括用于过滤血管内的血液的网格，特别是在诸如主动脉的动脉内，适于打开和关闭血管内的网状物的结构，致动结构的装置和气囊封堵器 通常包括围绕室的柔性材料。 所述方法通常包括以下步骤：将网状物引入血管以捕获栓塞材料，如果需要，在过滤过程中调整网孔，使球囊封堵器膨胀以封闭网孔上游的容器，然后使气囊放气 闭塞器并从血管中除去网状物和捕获的异物。 此外，可视化技术用于确保有效的过滤。

公开(公告)号：US06706033B1

公开(公告)日：2004-03-16

申请号：US09365650

申请日：1999-08-02

申请人： Lorraine Mangosong Martinez ,  Jobert Balceta ,  Kevin Hahnen ,  Bruce Addis ,  Timothy J. Wood ,  Roman Turovskiy ,  Richard O. Murphy ,  Tracy D. Maahs

发明人： Lorraine Mangosong Martinez ,  Jobert Balceta ,  Kevin Hahnen ,  Bruce Addis ,  Timothy J. Wood ,  Roman Turovskiy ,  Richard O. Murphy ,  Tracy D. Maahs

IPC分类号： A61M2900

CPC分类号： A61B17/3415 ,  A61B17/3421 ,  A61B2017/00243 ,  A61B2017/22067 ,  A61B2017/3445 ,  A61F2/013 ,  A61F2002/018 ,  A61F2230/0006 ,  A61F2230/0065 ,  A61F2230/0067 ,  A61F2230/008

摘要： Modular systems comprising a cannula and at least one access port adjacent to a distal end of the cannula provide insertion of one or more therapeutic or diagnostic devices into a vessel or cardiac tissue through a single incision site. Other embodiments include a vessel introducer or multi-port introducer. The devices can be operated in combination or independently. The systems can be employed to provide multiple therapies, including blood perfusion, filtration, aspiration, vessel occlusion, atherectomy, and endoscopic devices. Methods of using the system for vessel cannulation are also disclosed herein.

摘要翻译： 包括套管和邻近套管远端的至少一个进入口的模块化系统通过单个切口部位将一个或多个治疗或诊断装置插入血管或心脏组织。 其他实施例包括血管引入器或多端口引导器。 设备可以组合或独立运行。 该系统可用于提供多种疗法，包括血液灌注，过滤，抽吸，血管闭塞，粥样斑块切除术和内窥镜装置。 本文还公开了使用该系统用于血管插管的方法。

公开(公告)号：US20130138151A1

公开(公告)日：2013-05-30

申请号：US13748302

申请日：2013-01-23

申请人： Tracy D. Maahs ,  Marvin C. Elmer ,  Richard C. Ewers

发明人： Tracy D. Maahs ,  Marvin C. Elmer ,  Richard C. Ewers

IPC分类号： A61B17/04

CPC分类号： A61B17/0401 ,  A61B17/0469 ,  A61B17/0482 ,  A61B17/0644 ,  A61B2017/00827 ,  A61B2017/00867 ,  A61B2017/0409 ,  A61B2017/0419 ,  A61B2017/0454 ,  A61B2017/0464 ,  A61B2017/0496 ,  A61B2017/06052 ,  A61B2090/037

摘要： Apparatus and methods optimize anchoring force in securing tissue folds. Over-compression of the tissue directly underlying the anchors is avoided by utilizing tissue anchors having expandable designs configured to minimize contact area between the anchor and tissue. When the anchor is in its expanded configuration, a load is applied to the anchor until it is optimally configured to accommodate a range of deflections while the anchor itself exerts a substantially constant force against the tissue.

摘要翻译： 装置和方法优化固定组织褶皱的锚固力。 通过使用具有可扩展设计的组织锚来避免直接位于锚固器下面的组织的过度压缩，所述组织锚定构造成使锚和组织之间的接触面积最小化。 当锚固件处于其膨胀构型时，将负载施加到锚固件，直到其被最佳地构造成适应一定范围的偏转，同时锚固件本身对组织施加基本恒定的力。

公开(公告)号：US08439898B2

公开(公告)日：2013-05-14

申请号：US12486578

申请日：2009-06-17

申请人： Cang C. Lam ,  Stuart Moran ,  Tracy D. Maahs ,  John Fernando Rodriguez ,  Seferino Enrique Torres ,  Wesley Lummis

发明人： Cang C. Lam ,  Stuart Moran ,  Tracy D. Maahs ,  John Fernando Rodriguez ,  Seferino Enrique Torres ,  Wesley Lummis

IPC分类号： A61B17/00

CPC分类号： A61B1/018 ,  A61B17/0401 ,  A61B17/0487 ,  A61B17/29 ,  A61B2017/00353 ,  A61B2017/0409 ,  A61B2017/0417 ,  A61B2017/0464 ,  A61B2017/06052 ,  A61B2017/2905 ,  A61B2017/2916

摘要： An endoscopic tissue anchor deployment device includes a handle, an elongated shaft defining an internal lumen, and an end effector attached to the distal end of the elongated shaft. A tissue anchor catheter is removably inserted through the lumen of the elongated shaft, the catheter having a tissue anchor assembly that is deployable from its distal end. In some embodiments, the handle includes a pin and track assembly that define a series of handle actuation steps corresponding to deployment steps for the deployment device end effector and the tissue anchor catheter. In some embodiments, the handle includes a catheter stop member that prevents movement of the tissue anchor catheter under certain circumstances, and a handle stop member that prevents actuation of the handle under certain circumstances.

摘要翻译： 内窥镜组织锚定部署装置包括手柄，限定内腔的细长轴和附接到细长轴的远端的端部执行器。 组织锚导管可移除地插入穿过细长轴的内腔，该导管具有可从其远端展开的组织锚组件。 在一些实施例中，手柄包括销和轨道组件，其限定对应于展开装置端部执行器和组织锚固导管的展开步骤的一系列手柄致动步骤。 在一些实施例中，手柄包括防止组织锚固导管在某些情况下移动的导管止动构件以及在某些情况下阻止手柄致动的手柄止动构件。

公开(公告)号：US20130041214A1

公开(公告)日：2013-02-14

申请号：US13597072

申请日：2012-08-28

申请人： Tracy D. Maahs ,  Richard C. Ewers ,  Arvin T. Chang ,  Chris Rothe ,  Eugene C. Chen ,  Marvin C. Elmer ,  Gilbert Madrid ,  Kabir Gambhir

发明人： Tracy D. Maahs ,  Richard C. Ewers ,  Arvin T. Chang ,  Chris Rothe ,  Eugene C. Chen ,  Marvin C. Elmer ,  Gilbert Madrid ,  Kabir Gambhir

IPC分类号： A61B1/05 ,  A61B1/018

CPC分类号： A61B1/0051 ,  A61B1/00085 ,  A61B1/00089 ,  A61B1/00098 ,  A61B1/00179 ,  A61B1/00183 ,  A61B1/018 ,  A61B1/05

摘要： Methods and apparatus for off-axis visualization are described herein. An endoluminal tissue manipulation assembly is disclosed which provides for a stable endoluminal platform and which also provides for effective triangulation of tools. Such an apparatus may comprise an optionally shape-lockable elongate body defining a longitudinal axis and adapted for endoluminal advancement in a patient body, at least one articulatable visualization lumen disposed near or at a distal region of the elongate body, the at least one articulating visualization lumen being adapted to articulate off-axis relative to a longitudinal axis of the elongate body, and at least one articulatable tool arm member disposed near or at the distal region of the elongate body, the at least one articulatable tool arm member being adapted to articulate off-axis and manipulate a tissue region of interest.

摘要翻译： 本文描述了用于离轴可视化的方法和装置。 公开了一种腔内组织操作组件，其提供稳定的内腔平台，并且还提供工具的有效三角测量。 这种装置可以包括限定纵向轴线并且适于在患者体内进行腔内前进的可选形状可锁定细长体，至少一个可伸长的可视腔，其设置在细长体的远端区域附近或位于该远端区域处，该至少一个铰接可视化 内腔适于相对于细长主体的纵向轴线偏轴关节，以及设置在细长主体的远侧区域附近或其附近的至少一个可铰接工具臂构件，所述至少一个可铰接工具臂构件适于铰接 离轴并且操纵感兴趣的组织区域。

公开(公告)号：US20120238952A1

公开(公告)日：2012-09-20

申请号：US13483371

申请日：2012-05-30

申请人： Sean Mitchell ,  Richard C. Ewers ,  Tracy D. Maahs

发明人： Sean Mitchell ,  Richard C. Ewers ,  Tracy D. Maahs

IPC分类号： A61M25/092

CPC分类号： A61B1/0057 ,  A61B1/0052 ,  A61B1/0055 ,  A61B1/008 ,  A61B1/012 ,  A61M25/0147

摘要： An endoluminal surgical instrument has first and second steering controls on a handle. A flexible shaft attached to the handle has a distal steerable end including a first link and a second link separated by a plurality of intermediate links. First and second steering elements, such as pairs of steering wires, are linked to first and second steering controls and to the first and, second links. One or more of the links is pivotable through an angle of at least 30 degrees relative to an adjoining link. The set back position of the second steering elements from the first steering elements, and the pivoting capability of the links allows the steerable end to be steered into a small bend radius. This makes the instrument highly maneuverable for use in endoluminal surgery, such as incision-less surgery of the stomach.

摘要翻译： 腔内手术器械在手柄上具有第一和第二转向控制。 附接到手柄的柔性轴具有远端可操纵端，其包括由多个中间连杆分隔的第一连杆和第二连杆。 第一和第二转向元件，例如成对的转向线，被连接到第一和第二转向控制以及第一和第二连杆。 连接件中的一个或多个可相对于邻接连杆枢转至少30度的角度。 来自第一转向元件的第二转向元件的回退位置以及链节的枢转能力允许可转向端转向小的弯曲半径。 这使得仪器高度可操作地用于腔内手术，例如无切口的胃手术。