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公开(公告)号:US20120208819A1
公开(公告)日:2012-08-16
申请号:US13499835
申请日:2010-10-05
申请人: Joseph Arndt , Timothy Chan , Kevin Guckian , Gnanasambandam Kumaravel , Wen-Cherng Lee , Edward Yin-Shiang Lin , Daniel Scott , Lihong Sun , Jermaine Thomas , Kurt van Vloten , Deping Wang , Lei Zhang , Daniel Erlanson
发明人: Joseph Arndt , Timothy Chan , Kevin Guckian , Gnanasambandam Kumaravel , Wen-Cherng Lee , Edward Yin-Shiang Lin , Daniel Scott , Lihong Sun , Jermaine Thomas , Kurt van Vloten , Deping Wang , Lei Zhang , Daniel Erlanson
IPC分类号: A61K31/53 , C07D401/14 , C07D409/14 , A61P35/00 , A61K31/444 , A61K31/519 , A61K31/4439 , A61K31/517 , C07D471/04 , C07D401/12
CPC分类号: C07D471/04 , A61K31/437 , A61K31/4439 , A61K31/444 , A61K31/452 , A61K31/4725 , A61K31/496 , A61K31/497 , A61K31/498 , A61K31/4985 , A61K31/517 , A61K31/519 , A61K31/53 , A61K31/5377 , A61K31/5383 , C07D213/82 , C07D213/85 , C07D241/26 , C07D241/28 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D405/14 , C07D409/04 , C07D409/14 , C07D417/14 , C07D473/34 , C07D487/04 , C07D491/052 , C07D498/04 , C07D519/00
摘要: The present invention provides compounds useful as inhibitors of PDK1. The present invention also provides compositions thereof, and methods of treating PDK1-mediated diseases.
摘要翻译: 本发明提供了可用作PDK1抑制剂的化合物。 本发明还提供了其组合物,以及治疗PDK1介导的疾病的方法。
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公开(公告)号:US09546165B2
公开(公告)日:2017-01-17
申请号:US13499835
申请日:2010-10-05
申请人: Joseph Arndt , Timothy Chan , Kevin Guckian , Gnanasambandam Kumaravel , Wen-Cherng Lee , Edward Yin-Shiang Lin , Daniel Scott , Lihong Sun , Jermaine Thomas , Kurt van Vloten , Deping Wang , Lei Zhang , Daniel Erlanson
发明人: Joseph Arndt , Timothy Chan , Kevin Guckian , Gnanasambandam Kumaravel , Wen-Cherng Lee , Edward Yin-Shiang Lin , Daniel Scott , Lihong Sun , Jermaine Thomas , Kurt van Vloten , Deping Wang , Lei Zhang , Daniel Erlanson
IPC分类号: C07D471/04 , C07D487/04 , C07D239/94 , C07D241/26 , C07D213/82 , C07D213/85 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D405/14 , C07D409/04 , C07D409/14 , C07D417/14 , C07D473/34 , C07D491/052 , C07D519/00 , C07D241/28 , C07D498/04
CPC分类号: C07D471/04 , A61K31/437 , A61K31/4439 , A61K31/444 , A61K31/452 , A61K31/4725 , A61K31/496 , A61K31/497 , A61K31/498 , A61K31/4985 , A61K31/517 , A61K31/519 , A61K31/53 , A61K31/5377 , A61K31/5383 , C07D213/82 , C07D213/85 , C07D241/26 , C07D241/28 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D405/14 , C07D409/04 , C07D409/14 , C07D417/14 , C07D473/34 , C07D487/04 , C07D491/052 , C07D498/04 , C07D519/00
摘要: The present invention provides compounds useful as inhibitors of PDK1. The present invention also provides compositions thereof, and methods of treating PDK1-mediated diseases.
摘要翻译: 本发明提供了可用作PDK1抑制剂的化合物。 本发明还提供了其组合物,以及治疗PDK1介导的疾病的方法。
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公开(公告)号:US20100144730A1
公开(公告)日:2010-06-10
申请号:US12307104
申请日:2007-07-02
申请人: Kenneth Egnard Lind , Kathy Cao , Edward Yin-shiang Lin , Thinh Ba Nguyen , Bradley T. Tangonan , Daniel A. Erlanson , Kevin Guckian , Robert Lowell Simmons , Wen-cherng Lee , Lihong Sun , Stig Hansen , Nuzhat Pathan , Lei Zhang
发明人: Kenneth Egnard Lind , Kathy Cao , Edward Yin-shiang Lin , Thinh Ba Nguyen , Bradley T. Tangonan , Daniel A. Erlanson , Kevin Guckian , Robert Lowell Simmons , Wen-cherng Lee , Lihong Sun , Stig Hansen , Nuzhat Pathan , Lei Zhang
IPC分类号: A61K31/437 , C07D471/04 , C07D487/04 , C07D413/14 , A61K31/519 , A61K31/5377 , A61P35/00
CPC分类号: C07D471/04 , A61K31/4412 , A61K31/443 , A61K31/4436 , A61K31/4439 , A61K31/444 , A61K31/4985 , A61K31/506 , A61K31/519 , A61K31/5377 , C07D211/86 , C07D213/64 , C07D401/12 , C07D401/14 , C07D405/12 , C07D405/14 , C07D407/14 , C07D409/12 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D487/04
摘要: The present invention provides pyridinonyl PDK1 inhibitors and methods of treating cancer using the same.
摘要翻译: 本发明提供吡啶基PDK1抑制剂和使用其制备癌症的方法。
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公开(公告)号:US08778977B2
公开(公告)日:2014-07-15
申请号:US12307104
申请日:2007-07-02
申请人: Kenneth Egnard Lind , Kathy Cao , Edward Yin-shiang Lin , Thinh Ba Nguyen , Bradley T. Tangonan , Daniel A. Erlanson , Kevin Guckian , Robert Lowell Simmons , Wen-cherng Lee , Lihong Sun , Stig Hansen , Nuzhat Pathan , Lei Zhang
发明人: Kenneth Egnard Lind , Kathy Cao , Edward Yin-shiang Lin , Thinh Ba Nguyen , Bradley T. Tangonan , Daniel A. Erlanson , Kevin Guckian , Robert Lowell Simmons , Wen-cherng Lee , Lihong Sun , Stig Hansen , Nuzhat Pathan , Lei Zhang
IPC分类号: A61K31/5377 , A61K31/506 , A61K31/519 , A61K31/4985 , A61K31/444 , A61K31/4439 , A61K31/4436 , A61K31/443 , A61K31/4412 , C07D487/04 , C07D471/04 , C07D417/14 , C07D417/12 , C07D413/14 , C07D413/12 , C07D409/14 , C07D409/12 , C07D405/14 , C07D405/12 , C07D401/14 , C07D401/12 , C07D211/86
CPC分类号: C07D471/04 , A61K31/4412 , A61K31/443 , A61K31/4436 , A61K31/4439 , A61K31/444 , A61K31/4985 , A61K31/506 , A61K31/519 , A61K31/5377 , C07D211/86 , C07D213/64 , C07D401/12 , C07D401/14 , C07D405/12 , C07D405/14 , C07D407/14 , C07D409/12 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D487/04
摘要: The present invention provides pyridinonyl PDK1 inhibitors and methods of treating cancer using the same.
摘要翻译: 本发明提供吡啶基PDK1抑制剂和使用其制备癌症的方法。
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5.
公开(公告)号:US20240338071A1
公开(公告)日:2024-10-10
申请号:US18748987
申请日:2024-06-20
申请人: Lei Zhang , Youjean Cho , Daekun Kim , Ava Robinson , Yu Jiang Tham , Rajan Vaish , Andrés Monroy-Hernández
发明人: Lei Zhang , Youjean Cho , Daekun Kim , Ava Robinson , Yu Jiang Tham , Rajan Vaish , Andrés Monroy-Hernández
CPC分类号: G06F3/011 , G06F1/163 , G06T19/006
摘要: Described are virtual AR interfaces for generating a virtual rotational interface for the purpose of controlling connected IoT devices using the inertial measurement unit (IMU) of a portable electronic device. The IMU control application enables a user of a portable electronic device to activate a virtual rotational interface overlay on a display and adjust a feature of a connected IoT product by rotating a portable electronic device. The device IMU moves a slider on the virtual rotational interface. The IMU control application sends a control signal to the IoT product which executes an action in accordance with the slider position. The virtual rotational interface is presented on the display as a virtual object in an AR environment. The IMU control application detects the device orientation (in the physical environment) and in response presents a corresponding slider element on the virtual rotational interface (in the AR environment).
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公开(公告)号:USD998204S1
公开(公告)日:2023-09-05
申请号:US29850953
申请日:2022-08-24
申请人: Lei Zhang
设计人: Lei Zhang
摘要: FIG. 1 is a front and top perspective view of a flashlight, showing my new design;
FIG. 2 is a right side elevation view thereof;
FIG. 3 is a left side elevation view thereof;
FIG. 4 is a front elevation view thereof;
FIG. 5 is a rear elevation view thereof;
FIG. 6 is a top plan view thereof;
FIG. 7 is a bottom plan view thereof;
FIG. 8 is an enlarged perspective view of detail “8” identified in FIG. 1; and,
FIG. 9 is an enlarged rear elevation view of detail “9” identified in FIG. 5.
The dashed broken lines in the drawings illustrate portions of the article and form no part of the claimed design. The dash-dot-dash broken lines in FIGS. 1, 5, 8, and 9 are for the purpose of depicting the enlarged views and form no part of the claimed design.-
7.
公开(公告)号:US10684811B2
公开(公告)日:2020-06-16
申请号:US15856375
申请日:2017-12-28
申请人: Jason Monroe , Christopher S. Welch , Lei Zhang
发明人: Jason Monroe , Christopher S. Welch , Lei Zhang
IPC分类号: G06F3/14 , B60Q3/12 , B60Q1/50 , B60Q3/10 , B60K37/04 , B60R11/00 , B60R11/04 , B60R16/02 , B60Q3/80 , B60Q3/74 , B60Q3/51 , B60Q1/32 , B60Q3/233 , G06F3/0488 , G06F3/0482 , G06F3/0484 , B60K35/00
摘要: A vehicle includes at least one display and a central controller in signal communication with the at least one display. The central controller is configured to detect a plurality of unique user profiles associated with peripheral electronic user devices located within the vehicle, and to establish signal communication with the peripheral electronic user devices located within the vehicle.
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公开(公告)号:US10521179B2
公开(公告)日:2019-12-31
申请号:US15856344
申请日:2017-12-28
申请人: Jason Monroe , Christopher S. Welch , Lei Zhang
发明人: Jason Monroe , Christopher S. Welch , Lei Zhang
IPC分类号: G06F3/14 , B60Q3/80 , B60Q3/74 , B60Q3/51 , B60Q1/32 , B60Q3/233 , G06F3/0488 , G06F3/0482 , G06F3/0484 , B60Q3/10 , B60K37/04 , B60R11/00 , B60R11/04 , B60R16/02 , B60Q1/50 , B60Q3/12 , B60K35/00
摘要: A vehicle includes an interior cabin and a plurality of modular docking stations fixedly disposed in the interior cabin. Each modular docking station is configured to removably receive one or more modular components. The one or more modular components interchangeably connect to the plurality of modular docking stations to enable relocation of each modular component of the one or more modular components in a desired modular docking station of the plurality of docking stations.
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公开(公告)号:US10378365B2
公开(公告)日:2019-08-13
申请号:US14238626
申请日:2012-07-11
申请人: Feng Lin , Renji Zhang , Qianming Gong , Lei Zhang , Ting Zhang , Xiao Yuan , Wentao Yan
发明人: Feng Lin , Renji Zhang , Qianming Gong , Lei Zhang , Ting Zhang , Xiao Yuan , Wentao Yan
摘要: Disclosed is a turbine rotor device for a gas turbine, the turbine rotor device comprising a turbine rotor body, and a pre-stressed fiber-wound layer, wherein the pre-stressed fiber-wound layer is wound on the periphery of the turbine rotor body to exert a predetermined pre-loading force on the turbine rotor body. Additionally, a rotor, and a gas turbine and a turbine engine having the turbine rotor device are also provided.
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公开(公告)号:US10174736B2
公开(公告)日:2019-01-08
申请号:US14443021
申请日:2015-05-07
申请人: Lei Zhang
发明人: Lei Zhang
摘要: The present invention provides an emergency starting device, including a first output end and a second output end, wherein the first output end is used for being connected to a positive electrode of an accumulator battery in an engine starting system and the second output end is used for being connected to a negative electrode of the accumulator battery; the device includes a super-capacitor, a controller and a DC-DC booster circuit, wherein the controller receives first electrical signal from the accumulator battery and electrically connects the super-capacitor and the accumulator battery to start the engine with energy stored in the super-capacitor when the first electrical signal changes suddenly, the DC-DC booster circuit increases the output voltage of the accumulator battery to charge the super-capacitor. The invention further provides an emergency starting method accordingly. By using the super-capacitor, the controller and the DC-DC booster circuit the invention fits in various severe environments and can start an engine in emergency permanently and effectively.
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