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    Method of measuring cardiac related parameters non-invasively via the lung during spontaneous and controlled ventilation
    6.
    发明授权
    Method of measuring cardiac related parameters non-invasively via the lung during spontaneous and controlled ventilation 失效
    在自发和受控通气期间通过肺非侵入性测量心脏相关参数的方法

    公开(公告)号：US08460202B2

    公开(公告)日：2013-06-11

    申请号：US10545562

    申请日：2004-02-18

    申请人： Joseph Fisher ,  David Preiss ,  Takafumi Asami ,  Alex Vesely ,  Eltan Prisman ,  Ron Somogyi ,  Steve Iscoe

    发明人： Joseph Fisher ,  David Preiss ,  Takafumi Asami ,  Alex Vesely ,  Eltan Prisman ,  Ron Somogyi ,  Steve Iscoe

    IPC分类号： A61B5/08

    CPC分类号： A61B5/0205 ,  A61B5/083 ,  A61B5/14551 ,  A61B5/7225 ,  A61B5/7278 ,  A61M16/08 ,  A61M16/0833 ,  A61M16/085 ,  A61M16/0858 ,  A61M16/202 ,  A61M16/205 ,  A61M16/206 ,  A61M16/208 ,  A61M16/22

    摘要： An apparatus to measure cardiac output (Q) and other parameters such as alveolar ventilation (VA), minute CO2 elimination from the lung (VCO2), minute oxygen consumption (VO2), oxygenated mixed venous partial pressure of CO2, (PvCO2-oxy), true mixed venous partial pressure of CO2(PvCO2), PaCO2, mixed venous oxygen saturation (SvO2), pulmonary shunt, and anatomical dead space, consisting of: a) a breathing circuit with characteristics that: i. on exhalation, exhaled gas is kept substantially separate from inhaled gas; ii. on inhalation, when VE is greater than FGS flow, the subject inhales FGS first and then inhales a gas that is substantially SGS, for the balance of inhalation; b) gas sensor means for monitoring gas concentrations at the patient-circuit interface c) a first gas set (FGS), and a second gas set (SGS), said second gas set which may comprise previously exhaled gases or exogenous gases or both d) a gas flow control means for controlling the rate of FGS flow into the breathing circuit e) means to identify phase of breathing, said means may consist of pressure sensors or analysis of signal generated by gas sensors or other means known to those skilled in the art; f) machine intelligence consisting of a computer or logic circuit capable of controlling the gas flow control means, receiving the output of the gas sensor means and means to identify phase of breathing, and performing the calculations for measuring cardiac output and other parameters as outlined in the disclosure.

    摘要翻译： 测量心输出量（Q）和其他参数如肺泡通气（VA），从肺中消除二氧化碳（VCO2），微量氧消耗（VO2），氧合混合静脉分压CO2（PvCO2-氧） ，真正的混合静脉分压二氧化碳（PvCO2），PaCO2，混合静脉血氧饱和度（SvO2），肺动脉分流和解剖死空间组成：a）具有以下特征的呼吸回路： 在呼气时，呼出气体与吸入气体基本分离; ii。 吸入时，当VE大于FGS流量时，受试者首先吸入FGS，然后吸入基本上为SGS的气体，用于吸入余量; b）用于监测患者 - 电路接口处的气体浓度的气体传感器装置c）第一气体组（FGS）和第二气体组（SGS），所述第二气体组可以包括先前呼出的气体或外来气体或二者 ）用于控制FGS流入呼吸回路的速率的气体流量控制装置e）识别呼吸相位的装置，所述装置可包括压力传感器或由气体传感器产生的信号分析或本领域技术人员已知的其它装置 艺术; f）机器智能，包括能够控制气体流量控制装置的计算机或逻辑电路，接收气体传感器装置的输出和识别呼吸相位的装置，以及执行用于测量心输出量和其他参数的计算，如 披露。

    Method of measuring cardiac related parameters non-invasively via the lung during spontaneous and controlled ventilation
    7.
    发明申请
    Method of measuring cardiac related parameters non-invasively via the lung during spontaneous and controlled ventilation 失效
    在自发和受控通气期间通过肺非侵入性测量心脏相关参数的方法

    公开(公告)号：US20070062531A1

    公开(公告)日：2007-03-22

    申请号：US10545562

    申请日：2004-02-18

    申请人： Joseph Fisher ,  David Preiss ,  Takafumi Azami ,  Alex Vesely ,  Eltan Prisman ,  Ron Somogyi ,  Dan Nayot

    发明人： Joseph Fisher ,  David Preiss ,  Takafumi Azami ,  Alex Vesely ,  Eltan Prisman ,  Ron Somogyi ,  Dan Nayot

    IPC分类号： F16K31/02 ,  A61M16/00

    CPC分类号： A61B5/0205 ,  A61B5/083 ,  A61B5/14551 ,  A61B5/7225 ,  A61B5/7278 ,  A61M16/08 ,  A61M16/0833 ,  A61M16/085 ,  A61M16/0858 ,  A61M16/202 ,  A61M16/205 ,  A61M16/206 ,  A61M16/208 ,  A61M16/22

    摘要： An apparatus to measure cardiac output (Q) and other parameters such as alveolar ventilation (VA), minute CO2 elimination from the lung (VCO2 ), minute oxygen consumption (VO2), oxygenated mixed venous partial pressure of CO2, (PvCO2-oxy), true mixed venous partial pressure of CO2(PvCO2), PaCO2, mixed venous oxygen saturation (SvO2), pulmonary shunt, and anatomical dead space, consisting of: a) a breathing circuit with characteristics that: i. on exhalation, exhaled gas is kept substantially separate from inhaled gas; ii. oninhalation, when VE is greater than FGS flow, the subject inhales FGS first and then inhales a gas that is substantially SGS, for the balance of inhalation; b) gas sensor means for monitoring gas concentrations at the patient-circuit interface c) a first gas set (FGS), and a second gas set (SGS), said second gas set which may comprise previously exhaled gases or exogenous gases or both d) a gas flow control means for controlling the rate of FGS flow into the breathing circuit e) means to identify phase of breathing, said means may consist of pressure sensors or analysis of signal generated by gas sensors or other means known to those skilled in the art; f) machine intelligence consisting of a computer or logic circuit capable of controlling the gas flow control means, receiving the output of the gas sensor means and means to identify phased of breathing, and performing the calculations for measuring cardiac output and other parameters as outlined in the disclosure.

    摘要翻译： 一种用于测量心输出量（Q）和其它参数（例如肺泡通气（VA）），从肺部消除的微小CO 2（VCO 2）的装置，微量氧消耗（ VO 2 2），CO 2氧合混合静脉分压，（PvCO 2 - 氧基），真正的混合静脉分压CO

    RELATIVE CONTRIBUTION OF THORACIC MUSCLES TO BREATHING
    8.
    发明申请
    RELATIVE CONTRIBUTION OF THORACIC MUSCLES TO BREATHING 审中-公开
    胸腔积液对呼吸的相关贡献

    公开(公告)号：US20110144516A1

    公开(公告)日：2011-06-16

    申请号：US12992837

    申请日：2009-05-15

    申请人： Joseph Fisher ,  Alex Vesely ,  Dahlia Balaban ,  James Duffin ,  Greg D. Wells

    发明人： Joseph Fisher ,  Alex Vesely ,  Dahlia Balaban ,  James Duffin ,  Greg D. Wells

    IPC分类号： A61B5/08

    CPC分类号： A61B5/036 ,  A61B5/037 ,  A61B5/091 ,  A61B5/205 ,  A61B5/412 ,  A61B5/4519

    摘要： A method and apparatus for evaluating the relative contribution of the diaphragm versus other thoracic muscles to breathing by obtaining measurements of parameters that correlate with changes in thoracic cavity and intra-abdominal cavity pressures over identical time increments and organizing the measurement data in manner that reveals whether the pressures changes are characteristic of the pattern of contemporaneous pressure changes in those cavities that accompany contraction and/or relaxation of the diaphragm muscles or whether the pressure changes are characteristic of the pattern of contemporaneous pressure changes in those cavities that accompany contraction and/or relaxation of the intercostal muscles.

    摘要翻译： 通过获得与相同时间增量的胸腔和腹腔压力变化相关的参数的测量来评估隔膜相对于其他胸肌对呼吸的相对贡献的方法和装置，并以揭示是否 压力变化是伴随膈肌收缩和/或放松的那些空腔中的同期压力变化的模式的特征，或压力变化是否伴随伴随收缩和/或松弛的那些空腔中的同期压力变化的模式的特征 的肋间肌肉。

    Portable isocapnia circuit and isocapnia method
    10.
    发明授权
    Portable isocapnia circuit and isocapnia method 有权
    便携式isocapnia电路和isocapnia方法

    公开(公告)号：US06612308B2

    公开(公告)日：2003-09-02

    申请号：US10093797

    申请日：2002-03-08

    申请人： Joseph Fisher ,  Alex Vesely ,  Hiroshi Sasano ,  Steve Iscoe ,  Alex Stenzler

    发明人： Joseph Fisher ,  Alex Vesely ,  Hiroshi Sasano ,  Steve Iscoe ,  Alex Stenzler

    IPC分类号： A62B700

    CPC分类号： A61M16/12 ,  A61M16/0045 ,  A61M16/08

    摘要： A portable isocapnia circuit and an isocapnia method. A breathing port of the circuit allows a subject to inhale and exhale. Connected to the breathing port, a bifurcate conduit has a first conduit branch and a second conduit branch. The first conduit branch has an atmospheric air inlet, from which the atmospheric air is provided for inhalation, an inspiratory check valve to allow a one-way flow of the atmospheric air, and an atmospheric air aspirator. The second conduit branch has a one-way expiratory check valve and a expiratory gas reservoir. A one-way check valve is used to interconnect the first and second conduit branch, from which the expiratory gas stored in the expiratory gas reservoir flows to the first conduit branch to mix with the atmospheric air when the minute ventilation exceeds the atmospheric air.

    摘要翻译： 便携式异卡路里电路和异味法。 电路的呼吸口允许受试者吸入并呼气。 连接到呼吸端口，分叉导管具有第一导管支路和第二导管支路。 第一管道分支具有大气空气入口，大气从该空气入口提供用于吸入，吸气止回阀允许大气空气的单向流动，以及大气抽气器。 第二导管分支具有单向呼气止回阀和呼气气体储存器。 单向止回阀用于互连第一和第二导管分支，当微小通气超过大气时，从呼吸气体储存器中吸入的呼吸气体流向第一导管支路与大气混合。