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1.发明申请SYSTEMS AND METHODS FOR THE TREATMENT OF BLADDER DYSFUNCTIONS USING NEUROMODULATION 审中-公开使用神经修复治疗刀片功能障碍的系统和方法公开(公告)号：US20100274310A1
公开(公告)日：2010-10-28
申请号：US12601195
申请日：2008-05-22
申请人： Joseph W. Boggs, II , Maria E. Bennett , Julie Grill , Joseph J. Mrva , Robert B. Strother , Geoffrey B. Thrope
发明人： Joseph W. Boggs, II , Maria E. Bennett , Julie Grill , Joseph J. Mrva , Robert B. Strother , Geoffrey B. Thrope
IPC分类号： A61N1/36
CPC分类号： A61N1/05 , A61M2205/054 , A61M2210/1067 , A61M2210/1089 , A61N1/0512 , A61N1/0524 , A61N1/36007 , A61N1/36107
摘要： Systems and Methods treat bladder dysfunctions using neuromodulation stimulation. Bladder emptying through stimulation of urethral afferents, and continence through stimulation of the dorsal genital nerve, is provided with one or more implanted pulse generators and one or more leads. A simple surgical procedure preserves all existing functions. A stimulating catheter is provided to be used as a clinical screening tool. The stimulating catheter is used to measure bladder pressures and stimulate the urethra at the same time.
摘要翻译： 系统和方法使用神经调节刺激治疗膀胱功能障碍。 通过刺激尿道传入的膀胱排空，以及通过刺激背部生殖神经的控制，设置有一个或多个植入的脉冲发生器和一个或多个引线。 简单的外科手术保留了所有现有的功能。 提供了一种刺激性导管，用作临床筛选工具。 刺激导管用于测量膀胱压力并同时刺激尿道。
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2.发明申请Systems and methods for bilateral stimulation of left and right branches of the dorsal genital nerves to treat urologic dysfunctions 审中-公开双侧刺激背部生殖神经左右分支的系统和方法，以治疗泌尿功能障碍公开(公告)号：US20080132969A1
公开(公告)日：2008-06-05
申请号：US11981113
申请日：2007-10-31
申请人： Maria E. Bennett , Julie Grill , Tina E. Lechman , Joseph J. Mrva , Jonathan L. Sakai , Robert B. Strother , Geoffrey B. Thrope , Therese M. Zmina
发明人： Maria E. Bennett , Julie Grill , Tina E. Lechman , Joseph J. Mrva , Jonathan L. Sakai , Robert B. Strother , Geoffrey B. Thrope , Therese M. Zmina
IPC分类号： A61N1/05
CPC分类号： A61N1/372 , A61N1/0521 , A61N1/0558 , A61N1/36007 , A61N1/36017 , A61N1/36107
摘要： Systems and methods treat urologic dysfunctions by implanting a lead and electrode in a tissue region affecting urologic function, and coupling the lead to an external pulse generator. If desired results are achieved, the external pulse generator is removed and an implantable pulse generator is implanted in an anterior pelvic region remote from the electrode. Bilateral stimulation of the left and/or right branches of the dorsal genital nerves using a single lead implanted in adipose or other tissue in the region at or near the pubic symphysis is able to treat urologic dysfunctions.
摘要翻译： 系统和方法通过将铅和电极植入影响泌尿功能的组织区域来治疗泌尿系统功能障碍，并将引线耦合到外部脉冲发生器。 如果达到期望的结果，则移除外部脉冲发生器，将植入式脉冲发生器植入远离电极的前部骨盆区域。 使用植入在耻骨联合或其附近区域的脂肪或其他组织中的单个导线来双侧刺激背生殖神经的左侧和/或右侧分支能够治疗泌尿功能障碍。
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3.发明申请Systems and methods for a trial stage and/or long-term treatment of disorders of the body using neurostimulation 审中-公开用于使用神经刺激的试验阶段和/或长期治疗身体障碍的系统和方法公开(公告)号：US20080161874A1
公开(公告)日：2008-07-03
申请号：US11981424
申请日：2007-10-31
申请人： Maria E. Bennett , Julie Grill , Tina E. Lechman , Joseph J. Mrva , Robert B. Strother , Geoffrey B. Thrope , Therese M. Zmina , Steven M. Galecki , Danny R. Pack
发明人： Maria E. Bennett , Julie Grill , Tina E. Lechman , Joseph J. Mrva , Robert B. Strother , Geoffrey B. Thrope , Therese M. Zmina , Steven M. Galecki , Danny R. Pack
IPC分类号： A61N1/00
CPC分类号： A61N1/36007 , A61N1/0524 , A61N1/36017 , A61N1/36021 , A61N1/36107 , A61N1/372
摘要： Systems and methods screen and/or treat disorders of the body using neurostimulation. A trial system implants a temporary or permanent percutaneous lead and couples the lead to an external pulse generator. The external pulse generator supplies a prescribed stimulation regime through the lead to a targeted tissue region. If an improvement in the treated disorder is achieved, use of the trial system may be continued, or an implantable system may be implanted.
摘要翻译： 系统和方法使用神经刺激来筛选和/或治疗身体的疾病。 试验系统植入临时或永久的经皮引线，并将引线耦合到外部脉冲发生器。 外部脉冲发生器通过引线将规定的刺激方案提供给目标组织区域。 如果治疗障碍得到改善，可以继续使用试验系统，或者植入可植入的系统。
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公开(公告)号：US07865250B2
公开(公告)日：2011-01-04
申请号：US11290736
申请日：2005-11-30
IPC分类号： A61N1/05
CPC分类号： A61N1/36007 , A61N1/0551 , A61N1/0556
摘要： Systems provide a stimulation electrode assembly sized and configured for placement in an adipose tissue region to stimulate a nerve in the adipose tissue region comprising an elongated lead sized and configured to be implanted within the adipose tissue region, the lead including at least two electrically conductive portions to apply electrical stimulation to nerve tissue in the adipose tissue region, and at least two expandable anchoring structures deployable from the lead to engage adipose tissue and resist dislodgment and/or migration of the at least two electrically conductive portions within the adipose tissue region.
摘要翻译： 系统提供一种刺激电极组件，其尺寸和构造适于放置在脂肪组织区域中以刺激脂肪组织区域中的神经，其包括尺寸和构造成植入脂肪组织区域中的细长导线，该引线包括至少两个导电部分 将电刺激施加到脂肪组织区域中的神经组织，以及至少两个可展开的锚定结构，其可从引导物展开以接合脂肪组织并抵抗脂肪组织区域内的至少两个导电部分的移动和/或迁移。
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5.发明授权Systems and methods of neuromodulation stimulation for the restoration of sexual function 有权用于恢复性功能的神经调节刺激的系统和方法公开(公告)号：US08805533B2
公开(公告)日：2014-08-12
申请号：US13031482
申请日：2011-02-21
IPC分类号： A61N1/36
CPC分类号： A61N1/05 , A61M2205/054 , A61M2210/1067 , A61M2210/1089 , A61N1/0512 , A61N1/0524 , A61N1/36007 , A61N1/36107
摘要： Systems and methods use an external and/or implantable pulse generator system for neuromodulation stimulation to treat sexual dysfunction by the unilateral or bilateral stimulation of a target nerve A and/or a target nerve B using one or more leads and electrodes implanted in tissue in the pelvic region. The electrical stimulation waveform may be conveyed to the target nerve A electrode for a first predetermined amount of time, and conveyed to the target nerve B electrode for a second predetermined amount of time.
摘要翻译： 系统和方法使用外部和/或可植入的脉冲发生器系统进行神经调节刺激，以通过使用植入组织中的一个或多个引线和电极单目或双侧刺激靶神经A和/或靶神经B来治疗性功能障碍 骨盆部位。 电刺激波形可以以第一预定量的时间传送到目标神经A电极，并且传送到目标神经B电极第二预定时间量。
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6.发明申请Portable assemblies, systems, and methods for providing functional or therapeutic neurostimulation 有权用于提供功能或治疗神经刺激的便携式组件，系统和方法公开(公告)号：US20100036445A1
公开(公告)日：2010-02-11
申请号：US12462384
申请日：2009-08-03
申请人： Johnathan L. Sakai , Maria E. Bennett , Joseph W. Boggs, II , Robert B. Strother , Geoffrey B. Thrope , Kenneth P. Rundle , Stuart F. Rubin
发明人： Johnathan L. Sakai , Maria E. Bennett , Joseph W. Boggs, II , Robert B. Strother , Geoffrey B. Thrope , Kenneth P. Rundle , Stuart F. Rubin
CPC分类号： A61N1/0496 , A61N1/0551 , A61N1/36003 , A61N1/36017 , A61N1/36021
摘要： Neurostimulation assemblies, systems, and methods make possible the providing of short-term therapy or diagnostic testing by providing electrical connections between muscles and/or nerves inside the body and stimulus generators and/or recording instruments mounted on the surface of the skin or carried outside the body. Neurostimulation assemblies, systems, and methods may include a carrier and an electronics pod, the electronics pod including stimulation generation circuitry and user interface components. A power source and/or flash memory may be incorporated in neurostimulation assembly and/or the return electrode. The assemblies, systems, and methods are adapted to provide coordinated neurostimulation to multiple regions of the body.
摘要翻译： 神经刺激组件，系统和方法可以通过提供身体内的肌肉和/或神经之间的电连接，以及安装在皮肤表面上或外部携带的刺激发生器和/或记录仪器来提供短期治疗或诊断测试 身体。 神经刺激组件，系统和方法可以包括载体和电子舱，电子舱包括刺激产生电路和用户界面组件。 电源和/或闪存可以并入神经刺激组件和/或返回电极中。 组件，系统和方法适于为身体的多个区域提供协调的神经刺激。
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7.发明授权Portable assemblies, systems, and methods for providing functional or therapeutic neurostimulation 有权用于提供功能或治疗神经刺激的便携式组件，系统和方法公开(公告)号：US08463383B2
公开(公告)日：2013-06-11
申请号：US12462384
申请日：2009-08-03
申请人： Johnathan L. Sakai , Maria E. Bennett , Joseph W. Boggs, II , Robert B. Strother , Geoffrey B. Thrope , Kenneth P. Rundle , Stuart F. Rubin
发明人： Johnathan L. Sakai , Maria E. Bennett , Joseph W. Boggs, II , Robert B. Strother , Geoffrey B. Thrope , Kenneth P. Rundle , Stuart F. Rubin
IPC分类号： A61N1/18
CPC分类号： A61N1/0496 , A61N1/0551 , A61N1/36003 , A61N1/36017 , A61N1/36021
摘要： Neurostimulation assemblies, systems, and methods make possible the providing of short-term therapy or diagnostic testing by providing electrical connections between muscles and/or nerves inside the body and stimulus generators and/or recording instruments mounted on the surface of the skin or carried outside the body. Neurostimulation assemblies, systems, and methods may include a carrier and an electronics pod, the electronics pod including stimulation generation circuitry and user interface components. A power source and/or flash memory may be incorporated in neurostimulation assembly and/or the return electrode. The assemblies, systems, and methods are adapted to provide coordinated neurostimulation to multiple regions of the body.
摘要翻译： 神经刺激组件，系统和方法可以通过提供身体内的肌肉和/或神经之间的电连接，以及安装在皮肤表面上或外部携带的刺激发生器和/或记录仪器来提供短期治疗或诊断测试 身体。 神经刺激组件，系统和方法可以包括载体和电子舱，电子舱包括刺激产生电路和用户界面组件。 电源和/或闪存可以并入神经刺激组件和/或返回电极中。 组件，系统和方法适于为身体的多个区域提供协调的神经刺激。
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8.发明授权Systems and methods for bilateral stimulation of left and right branches of the dorsal genital nerves to treat dysfunctions, such as urinary incontinence 失效用于双侧刺激背部生殖神经的左右分支以治疗功能障碍的系统和方法，例如尿失禁公开(公告)号：US07565198B2
公开(公告)日：2009-07-21
申请号：US11149654
申请日：2005-06-10
申请人： Maria Bennett , Robert B. Strother , Julie Grill , Joseph J. Mrva , Therese Zmina , Geoffrey B. Thrope
发明人： Maria Bennett , Robert B. Strother , Julie Grill , Joseph J. Mrva , Therese Zmina , Geoffrey B. Thrope
IPC分类号： A61N1/36
CPC分类号： A61N1/36007 , A61N1/05 , A61N1/0551 , A61N1/08 , A61N1/36017 , A61N1/36107 , A61N1/37229 , A61N1/37252 , A61N1/375 , A61N1/3754 , A61N1/3787
摘要： Systems and methods treat urinary incontinence by the bilateral stimulation of the left and/or right branches of the dorsal genital nerves using a single lead implanted in adipose or other tissue in the region at or near the pubic symphysis.
摘要翻译： 系统和方法通过双侧刺激背部生殖器神经的左侧和/或右侧分支来治疗尿失禁，其中使用植入在耻骨联合处或附近的区域中的脂肪或其他组织中的单个引线。
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9.发明授权公开(公告)号：US07343202B2
公开(公告)日：2008-03-11
申请号：US11150419
申请日：2005-06-10
IPC分类号： A61N1/36
CPC分类号： A61N1/36007 , A61N1/05 , A61N1/0524 , A61N1/0551 , A61N1/0558 , A61N1/372
摘要： Systems and methods provide a stimulation electrode assembly comprising an elongated lead sized and configured to be implanted within an adipose tissue region. The lead includes an electrically conductive portion to apply electrical stimulation to nerve or muscle in the adipose tissue region and at least one expandable anchoring structure deployable from the lead to engage adipose tissue and resist dislodgment and/or migration of the electrically conductive portion within the adipose tissue region.
摘要翻译： 系统和方法提供了一种刺激电极组件，其包括尺寸和构造成植入脂肪组织区域内的细长导线。 引线包括导电部分，以对脂肪组织区域中的神经或肌肉施加电刺激，以及至少一个可展开的锚定结构，其可从导线部署以接合脂肪组织并抵抗脂肪内的导电部分的移动和/或迁移 组织区域。
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10.发明授权Systems and methods including lead and electrode structures sized and configured for implantation in adipose tissue 有权包括铅和电极结构的系统和方法的尺寸和构造用于植入脂肪组织公开(公告)号：US08649870B2
公开(公告)日：2014-02-11
申请号：US11980989
申请日：2007-10-31
IPC分类号： A61N1/36
CPC分类号： A61N1/36007 , A61N1/05 , A61N1/0524 , A61N1/0551 , A61N1/0558 , A61N1/372
摘要： A stimulation electrode assembly comprises an elongated lead sized and configured to be implanted within an adipose tissue region. The lead includes an electrically conductive portion to apply electrical stimulation to nerve or muscle in the adipose tissue region and at least one expandable anchoring structure deployable from the lead to engage adipose tissue and resist dislodgment and/or migration of the electrically conductive portion within the adipose tissue region.
摘要翻译： 刺激电极组件包括细长的引线，其尺寸和构造被植入脂肪组织区域内。 引线包括导电部分，以对脂肪组织区域中的神经或肌肉施加电刺激，以及至少一个可展开的锚定结构，其可从引导部分展开以接合脂肪组织并抵抗脂肪内的导电部分的移动和/或迁移 组织区域。
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