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1.发明申请Methods, Systems and Devices for Treatment of Cerebrospinal Venous Insufficiency and Multiple Sclerosis 审中-公开用于治疗脑脊液静脉功能不全和多发性硬化的方法，系统和装置公开(公告)号：US20130211489A1
公开(公告)日：2013-08-15
申请号：US13578555
申请日：2011-02-08
申请人： Joshua Makower , Earl A. Bright, II , Theodore M. Bender , Joseph Cantanese, III , John Y. Chang , Thomas King , Clinton Slone , Theodore C. Lamson , Aziz Imraan
发明人： Joshua Makower , Earl A. Bright, II , Theodore M. Bender , Joseph Cantanese, III , John Y. Chang , Thomas King , Clinton Slone , Theodore C. Lamson , Aziz Imraan
IPC分类号： A61F2/06
CPC分类号： A61F2/06 , A61F2/885 , A61F2/89 , A61F2/915 , A61F2002/825 , A61F2220/0008 , A61F2220/0016 , A61F2230/0054
摘要： Methods and devices for relieving stenoses in, or otherwise improving blood flow through, body lumens. Although applicable in a variety of different body lumens, the methods and devices of this invention are specifically useable for relieving stenoses in, or otherwise improving blood flow through, veins which drain blood from the brain for treatment of multiple sclerosis or other neurodegenerative disorders that are caused, triggered or exacerbated by venous occlusion or venous insufficiency.
摘要翻译： 用于减轻体液流经或以其他方式改善身体流明的血流的方法和装置。 尽管适用于各种不同的体腔，本发明的方法和装置特别可用于缓解静脉中的狭窄或改善通过静脉的血液，所述静脉排出来自脑的血液用于治疗多发性硬化症或其它神经变性疾病 导致，触发或加重静脉闭塞或静脉功能不全。
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2.发明申请MINIMALLY INVASIVE, DIRECT DELIVERY METHODS FOR IMPLANTING OBESITY TREATMENT DEVICES 审中-公开用于植入治疗装置的最小的直接输送方法公开(公告)号：US20110172767A1
公开(公告)日：2011-07-14
申请号：US13015086
申请日：2011-01-27
申请人： Pankaj Rathi , Theodore M. Bender , Brian K. Shiu , Pablo G. Acosta , Joshua Makower , Shuji Uemura , Narvel M. Brooks, III , Robert M. George , Earl A. Bright, II , Dane A. Johnson , Matthew B. Newell , Marlo Dreissigacker , Crystine M. Lee
发明人： Pankaj Rathi , Theodore M. Bender , Brian K. Shiu , Pablo G. Acosta , Joshua Makower , Shuji Uemura , Narvel M. Brooks, III , Robert M. George , Earl A. Bright, II , Dane A. Johnson , Matthew B. Newell , Marlo Dreissigacker , Crystine M. Lee
CPC分类号： A61B17/3421 , A61B17/00234 , A61B17/0401 , A61B17/0469 , A61B17/06066 , A61B17/3439 , A61B17/3498 , A61B2017/00818 , A61B2017/0092 , A61B2017/0404 , A61B2017/0451 , A61B2017/0472 , A61B2017/2905 , A61B2017/320052 , A61B2017/3405 , A61B2017/3445 , A61B2017/3447 , A61B2017/3449 , A61B2017/349 , A61B2090/037 , A61B2090/061 , A61B2090/395 , A61F5/0003 , A61F5/003 , A61F5/0073 , A61F5/0089 , A61M25/0069 , Y10T156/10
摘要： A method includes selecting a template from a plurality of different sizes of templates based on measurements of the abdominal cavity of a patient; orienting the template on the patient at a location overlying the abdominal cavity to select an appropriate size implant using fluoroscopic imaging; marking an incision location and an indicator of an angle of approach; and removing the template from the patient, wherein marks made by the marking remain on the patient. Methods apparatus, instruments and implants for treating a patient are provided.
摘要翻译： 一种方法包括：基于患者的腹腔的测量从多个不同大小的模板中选择模板; 将模板定位在覆盖腹腔的位置处的患者身上，以使用荧光镜成像选择适当尺寸的植入物; 标记切口位置和接近角度的指示器; 以及从患者身上移除模板，其中由标记制成的标记保留在患者身上。 提供了用于治疗患者的方法装置，仪器和植入物。
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3.发明申请公开(公告)号：US20130178877A1
公开(公告)日：2013-07-11
申请号：US13631559
申请日：2012-09-28
申请人： Theodore M. Bender , Joshua Makower , Brian K. Shiu , Pablo G. Acosta , Robert M. George , Lisa Serventi , Ed Orbeta , Scott Early , Earl A. Bright, II , Timothy A. Limon
发明人： Theodore M. Bender , Joshua Makower , Brian K. Shiu , Pablo G. Acosta , Robert M. George , Lisa Serventi , Ed Orbeta , Scott Early , Earl A. Bright, II , Timothy A. Limon
IPC分类号： A61B17/12
CPC分类号： A61F5/0086 , A61B17/00234 , A61B17/0401 , A61B17/0466 , A61B17/0469 , A61B17/0487 , A61B17/062 , A61B2017/00314 , A61B2017/00818 , A61B2017/0404 , A61B2017/0409 , A61B2017/0414 , A61B2017/0417 , A61B2017/0427 , A61B2017/045 , A61B2017/0462 , A61B2017/0464 , A61B2017/0472 , A61B2017/06009 , A61B2017/06042 , A61B2017/2944 , A61B2017/306
摘要： Methods, instruments and systems are provided for separating opposite walls of the stomach by extragastric application of suction. Plication of the stomach can be performed between the separated walls after which the separate walls are brought back toward one another. In another aspect, methods, instruments, devices and systems are provided for reducing the effective volume of a stomach by performing one or more extragastric plications of the stomach.
摘要翻译： 提供了方法，仪器和系统，用于通过抽吸施加胃分离胃的相对壁。 可以在分离的壁之间进行胃的电镀，之后分离的壁彼此回到另一个处。 在另一方面，提供了通过进行胃的一次或多次腹部胃痛来减少胃的有效体积的方法，仪器，装置和系统。
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4.发明授权公开(公告)号：US08382775B1
公开(公告)日：2013-02-26
申请号：US13439059
申请日：2012-04-04
申请人： Theodore M. Bender , Joshua Makower , Brian K. Shiu , Pablo G. Acosta , Robert M. George , Lisa Serventi , Ed Orbeta , Scott Early , Earl A. Bright, II , Timothy A. Limon
发明人： Theodore M. Bender , Joshua Makower , Brian K. Shiu , Pablo G. Acosta , Robert M. George , Lisa Serventi , Ed Orbeta , Scott Early , Earl A. Bright, II , Timothy A. Limon
IPC分类号： A61B17/04
CPC分类号： A61B17/00 , A61B17/00234 , A61B17/0401 , A61B17/0466 , A61B17/0469 , A61B17/0487 , A61B17/062 , A61B2017/00314 , A61B2017/00818 , A61B2017/0404 , A61B2017/0409 , A61B2017/0414 , A61B2017/0417 , A61B2017/0427 , A61B2017/045 , A61B2017/0462 , A61B2017/0464 , A61B2017/0472 , A61B2017/06009 , A61B2017/06042 , A61B2017/2944 , A61B2017/306 , A61F5/0086
摘要： Methods, instruments and systems are provided for separating opposite walls of the stomach by extragastric application of suction. Plication of the stomach can be performed between the separated walls after which the separate walls are brought back toward one another. In another aspect, methods, instruments, devices and systems are provided for reducing the effective volume of a stomach by performing one or more extragastric plications of the stomach.
摘要翻译： 提供了方法，仪器和系统，用于通过抽吸施加胃分离胃的相对壁。 可以在分离的壁之间进行胃的电镀，之后分离的壁彼此回到另一个处。 在另一方面，提供了通过进行胃的一次或多次腹部胃痛来减少胃的有效体积的方法，仪器，装置和系统。
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5.发明申请METHOD AND SYSTEM FOR TREATING TARGET TISSUE WITHIN THE EUSTACHIAN TUBE 审中-公开用于治疗目标组织的方法和系统在EUSTACHIAN TUBE公开(公告)号：US20100198191A1
公开(公告)日：2010-08-05
申请号：US12649078
申请日：2009-12-29
申请人： Anton G. Clifford , Joshua Makower , John Y. Chang , John H. Morriss , Earl A. Bright, II , Eric Goldfarb , Julia D. Vrany
发明人： Anton G. Clifford , Joshua Makower , John Y. Chang , John H. Morriss , Earl A. Bright, II , Eric Goldfarb , Julia D. Vrany
CPC分类号： A61M29/02 , A61B1/227 , A61B1/233 , A61B5/036 , A61B5/415 , A61B8/12 , A61B17/24 , A61B18/08 , A61B18/20 , A61F11/002 , A61F11/004 , A61M25/0041 , A61M25/0054 , A61M25/0068 , A61M25/007 , A61M25/008 , A61M25/0662 , A61M25/09 , A61M25/10 , A61M25/1002 , A61M31/002 , A61M2025/0037 , A61M2025/0039 , A61M2025/09008 , A61M2025/09183 , A61M2025/105 , A61M2025/1054 , A61M2025/1086 , A61N7/02
摘要： Methods and systems for accessing a Eustachian tube of a patient are disclosed. The system includes a guide configured for passing into a nasal passage of the patient to position a distal tip of the catheter at or near a Eustachian tube, the guide having a distal tip with a bend having an angle between 30 and 90 degrees; and a guidewire configured to pass through the guide into the Eustachian tube. A device for providing therapy to the Eustachian tube is passed through the guide.
摘要翻译： 公开了用于访问患者的咽鼓管的方法和系统。 该系统包括引导件，其构造成用于进入患者的鼻通道以将导管的远侧末端定位在咽鼓管处或附近，该导管具有具有在30度和90度之间的角度的弯曲部的远端; 以及引导线，其构造成穿过所述引导件进入咽鼓管。 用于向咽鼓管提供治疗的装置通过引导件。
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公开(公告)号：US08435290B2
公开(公告)日：2013-05-07
申请号：US12730492
申请日：2010-03-24
申请人： Anton G. Clifford , Joshua Makower , John Y. Chang , John H. Morriss , Earl A. Bright, II , Eric Goldfarb , Julia D. Vrany , Ketan P. Muni , William E. Bolger , Joseph Roberson
发明人： Anton G. Clifford , Joshua Makower , John Y. Chang , John H. Morriss , Earl A. Bright, II , Eric Goldfarb , Julia D. Vrany , Ketan P. Muni , William E. Bolger , Joseph Roberson
IPC分类号： A61F2/18
CPC分类号： A61F11/002
摘要： Methods and devices for providing a gas pathway between the nasopharynx and the Eustachian tube are provided. One device may include a lumen with a valve. A portion of the valve may be tethered to adjacent muscle. Another portion of the valve may be tethered to adjacent cartilage. When the muscle contracts the valve may open through movement of the tethers, and provide a gas pathway between the nasopharynx and the Eustachian tube.
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7.发明申请System and Method For Treatment of Non-Ventilating Middle Ear by Providing a Gas Pathway Through the Nasopharynx 有权通过提供通过鼻咽的气道来治疗非通气中耳的系统和方法公开(公告)号：US20100305697A1
公开(公告)日：2010-12-02
申请号：US12730492
申请日：2010-03-24
申请人： Anton G. Clifford , Joshua Makower , John Y. Chang , John H. Morriss , Earl A. Bright, II , Eric Goldfarb , Julia D. Vrany , Ketan P. Muni , William E. Bolger , Joseph Roberson
发明人： Anton G. Clifford , Joshua Makower , John Y. Chang , John H. Morriss , Earl A. Bright, II , Eric Goldfarb , Julia D. Vrany , Ketan P. Muni , William E. Bolger , Joseph Roberson
CPC分类号： A61F11/002
摘要： Methods and devices for providing a gas pathway between the nasopharynx and the Eustachian tube are provided. One device may include a lumen with a valve. A portion of the valve may be tethered to adjacent muscle. Another portion of the valve may be tethered to adjacent cartilage. When the muscle contracts the valve may open through movement of the tethers, and provide a gas pathway between the nasopharynx and the Eustachian tube.
摘要翻译： 提供了用于在鼻咽和咽鼓管之间提供气体通路的方法和装置。 一个装置可以包括具有阀的内腔。 阀的一部分可以系在相邻的肌肉上。 阀的另一部分可以连接到相邻的软骨上。 当肌肉收缩时，阀可以通过系绳的移动而打开，并且在鼻咽和咽鼓管之间提供气体通路。
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8.发明申请Method and System for Accessing, Diagnosing and Treating Target Tissue Regions Within the Middle Ear and the Eustachian Tube 审中-公开方法和系统，用于访问，诊断和治疗中耳和咽鼓管内的目标组织区域公开(公告)号：US20090163890A1
公开(公告)日：2009-06-25
申请号：US12340226
申请日：2008-12-19
申请人： Anton Clifford , Joshua Makower , John Y. Chang , John H. Morriss , Earl A. Bright, II , Eric Goldfarb , Julia D. Vrany
发明人： Anton Clifford , Joshua Makower , John Y. Chang , John H. Morriss , Earl A. Bright, II , Eric Goldfarb , Julia D. Vrany
CPC分类号： A61B8/12 , A61B1/227 , A61B1/233 , A61B5/036 , A61B5/411 , A61B5/415 , A61B18/20 , A61F11/004 , A61M25/0026 , A61M25/0041 , A61M25/0068 , A61M25/007 , A61M25/008 , A61M25/09 , A61M25/10 , A61M31/002 , A61M2025/09008 , A61N7/02
摘要： Method and systems for accessing a Eustachian tube of a patient are disclosed. The system includes a guide configured for passing into a nasal passage of the patient to position a distal tip of the catheter at or near a Eustachian tube, the guide having distal tip with a bend having an angle between 30 and 90 degrees; and a guidewire configured to pass through the guide into the Eustachian tube.
摘要翻译： 公开了用于访问患者的咽鼓管的方法和系统。 该系统包括引导件，其构造成用于进入患者的鼻通道，以将导管的远侧末端定位在咽鼓管处或附近，该导管具有远侧尖端，弯曲部具有30度和90度之间的角度; 以及引导线，其构造成穿过所述引导件进入咽鼓管。
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公开(公告)号：US20100076269A1
公开(公告)日：2010-03-25
申请号：US12562828
申请日：2009-09-18
申请人： Joshua Makower , John Y. Chang , William M. Facteau , Eric Goldfarb , Ketan P. Muni , Earl A. Bright, II , Greg Garfield , Greg Liu , Thomas Jenkins , John H. Morriss , Julia D. Vrany , Hung V. Ha , Ronda M. Heiser , Scott M. Smith
发明人： Joshua Makower , John Y. Chang , William M. Facteau , Eric Goldfarb , Ketan P. Muni , Earl A. Bright, II , Greg Garfield , Greg Liu , Thomas Jenkins , John H. Morriss , Julia D. Vrany , Hung V. Ha , Ronda M. Heiser , Scott M. Smith
摘要： Systems and methods for treating paranasal sinuses in a head of a patient include, for example, forming an opening through a canine fossa into a maxillary paranasal sinus and performing a procedure such as a balloon catheter dilation of the maxillary sinus ostium. In some embodiments, one or more procedures other than a balloon dilation procedure may be performed. In some embodiments, a combination of balloon dilation and one or more other procedures may be performed. Various approaches involve employing medical devices to accomplish alternative treatment modalities as well as taking alternative routes to the interventional site.
摘要翻译： 用于治疗患者头部鼻窦的系统和方法包括例如通过犬窝形成通向上颌鼻旁窦的开口，并执行诸如上颌窦口的气囊导管扩张的过程。 在一些实施例中，可以执行除球囊扩张程序之外的一个或多个程序。 在一些实施例中，可以执行球囊扩张和一个或多个其它程序的组合。 各种方法涉及采用医疗设备来完成替代治疗方式，以及采取替代途径到介入部位。
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公开(公告)号：US08491606B2
公开(公告)日：2013-07-23
申请号：US12979065
申请日：2010-12-27
申请人： Ling-Kang Tong , Theodore C. Lamson , Joseph Catanese, III , R. James Yu , Daniel Merrick , Matthew McLean , James W. Niederjohn , Floria Cheng , Ben Thompson , Brian Y. Tachibana , Kristin Taylor , Earl A. Bright, II
发明人： Ling-Kang Tong , Theodore C. Lamson , Joseph Catanese, III , R. James Yu , Daniel Merrick , Matthew McLean , James W. Niederjohn , Floria Cheng , Ben Thompson , Brian Y. Tachibana , Kristin Taylor , Earl A. Bright, II
IPC分类号： A61B17/10
CPC分类号： A61F2/04 , A61B17/00234 , A61B17/0401 , A61B17/0469 , A61B17/32 , A61B17/3478 , A61B17/42 , A61B2017/00022 , A61B2017/00274 , A61B2017/0046 , A61B2017/00792 , A61B2017/00796 , A61B2017/00805 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0464 , A61B2017/0479 , A61B2017/0488 , A61B2017/06052 , A61B2017/06095 , A61B2017/2923 , A61B2018/00547
摘要： A system and associated method for manipulating tissues and anatomical or other structures in medical applications for the purpose of treating diseases or disorders or other purposes. In one aspect, the system includes a delivery device configured to deploy and implant anchor devices for comprising, distracting and/or retracting the lobes of a prostate.
摘要翻译： 用于在医疗应用中操纵组织和解剖结构或其他结构以用于治疗疾病或障碍或其它目的的系统和相关方法。 在一个方面，该系统包括配置成部署和植入锚定装置的输送装置，用于包括，分散和/或缩回前列腺的叶。
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