摘要:
A main object is to provide a crystal of 6-fluoro-1-methyl-7-[4-(5-methyl-2-oxo-1,3-dioxolen-4-yl)-methyl-1-piperazinyl]-4-oxo-4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylic acid acetonitrile solvate (Compound B) which is an intermediate for producing preferentially the type III crystal of 6-fluoro-1-methyl-7-[4-(5-methyl-2-oxo-1,3-dioxolen-4-yl)methyl-1-piperazinyl]-4-oxo-4H-[1,3]-thiazeto[3,2-a]quinoline-3-carboxylic acid (Compound A). A crystal of Compound B can be preferentially precipitated by controlling the supersaturation concentration in crystalization using acetonitrile as a solvent. Subsequently, the type III crystal of Compound A can be produced by performing desolvation of the crystal.
摘要:
A main object is to provide a crystal of 6-fluoro-1-methyl-7-[4-(5-methyl-2-oxo-1,3-dioxolen-4-yl)-methyl-1-piperazinyl]-4-oxo-4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylic acid acetonitrile solvate (Compound B) which is an intermediate for producing preferentially the type III crystal of 6-fluoro-1-methyl-7-[4-(5-methyl-2-oxo-1,3-dioxolen-4-yl)methyl-1-piperazinyl]-4-oxo-4H-[1,3]-thiazeto[3,2-a]quinoline-3-carboxylic acid (Compound A). A crystal of Compound B can be preferentially precipitated by controlling the supersaturation concentration in crystalization using acetonitrile as a solvent. Subsequently, the type III crystal of Compound A can be produced by performing desolvation of the crystal.
摘要:
A light-emitting device reliably supplying electric power to a light-emitting element on a supporting base and securing heat dissipation, and a method of manufacturing the light-emitting device are provided. A light-emitting device includes: a light-emitting element arranged on a first supporting base; a package covering the first supporting base and the light-emitting element therewith, and supporting the first supporting base; and a thermal conductive member having ends which are bonded to the light-emitting element and the package, respectively, so as to also have a wiring function.
摘要:
There is provided an error correction control method of a transmission system on which a signal is transmitted from a first transmission apparatus to a second transmission apparatus, the error correction control method including: transmitting a signal for a mode change request to change an error correction mode from the second transmission apparatus to the first transmission apparatus; transmitting signals having a change timing value in a specific order with a specific period from the first transmission apparatus to the second transmission apparatus when the first transmission apparatus receives the mode change request; changing the error correction mode of the first transmission apparatus when the change timing value to be transmitted becomes a specific value in the first transmission apparatus; and changing the error correction mode of the second transmission apparatus in response to the change timing value received with the specific period from the first transmission apparatus.
摘要:
A vibrating gyroscope according to this invention includes a ring-shaped vibrating body 11 having a uniform plane, leg portions 15 flexibly supporting the ring-shaped vibrating body, a plurality of electrodes 13a, 13b, . . . , 13h that are disposed on the plane of or above the ring-shaped vibrating body and are formed with one of an upper-layer metallic film and a lower-layer metallic film, and a piezoelectric film being sandwiched between the upper-layer metallic film and the lower-layer metallic film in a thickness direction thereof. When one of the driving electrodes 13a for exciting a primary vibration of the ring-shaped vibrating body 11 in a vibration mode of cos Nθ is referred to as a reference driving electrode, the remaining plurality of electrodes 13b, . . . , 13h are disposed at specific positions. Such disposition allows this vibrating gyroscope to detect a secondary vibration inclusive of an out-of-plane vibration mode. A voltage for suppressing the secondary vibration is applied to a suppression electrode 13j.
摘要:
A magnetic-head supporting mechanism includes a slider having a chamfered bleed portion, a mounting portion on which the slider is mounted, a flexible finger portion extending in a longitudinal direction and supporting the mounting portion, a load beam extending in the longitudinal direction that connects at an end to a positioning mechanism, and that applies a load to the slider, and a regulating member extending from the load beam in the longitudinal direction for preventing change of an attitude of the slider when an angular attitude of the slider exceeds a predetermined angle. The regulating member extends over and above the flexible finger portion and over and above the slider and has an end in the longitudinal direction at a position approximately equal to an end of the flexible finger portion in the longitudinal direction.
摘要:
A vibrating gyroscope comprises a ring-shaped vibrating body (11) a leg portion (15) flexibly supporting the body (11) and having a fixed end, a fixed potential electrode (16), and a plurality of electrodes (13a-13d) with a piezoelectric film sandwiched between an upper and a lower-layer metallic film in a thickness direction thereof. When N is a natural number of 2 or more, the plurality of electrodes (13a-13d) include driving electrodes (13a) for a primary vibration in a vibration mode of cosNθ, which are each disposed (360/N)° apart from each other in a circumferential direction, first detection electrodes (13b) and second detection electrodes (13d) for detecting a secondary vibration generated when an angular velocity is applied to the body (11), which are each disposed in a certain region related to the driving electrode (13a) Each of the electrodes is also disposed in a certain region of the body (11).
摘要:
This DR steel sheet includes the following steel components: C: 0.02 to 0.06 mass %, Si: equal to or less than 0.03 mass %, Mn: 0.05 to 0.5 mass %, P: equal to or less than 0.02 mass %, S: equal to or less than 0.02 mass %, Al: 0.02 to 0.10 mass %, and N: 0.008 to 0.015 mass %. The amount of solute N (Ntotal−NasAlN) in the steel sheet containing a residual iron and inevitable impurities, is equal to or more than 0.006%; and the total stretchability in a rolling direction after aging is equal to or more than 10%, total stretchability in a sheet width direction after aging is equal to or more than 5%, and an average Lankford value after aging is equal to or less than 1.0.
摘要:
An object of the present invention is to create a novel indazole derivative having a spiro ring structure in a side chain, which is useful as a pharmaceutical, and to find a new pharmacological activity of the derivative. The present invention compound is represented by the general formula [I] and has an excellent Rho kinase inhibitory activity. In the formula, the ring X represents a benzene ring or a pyridine ring; R1 and R2 represent halogen, H, OH, alkoxy, cycloalkyloxy, aryloxy, alkyl, cycloalkyl or the like; R3 represents halogen, H or the like; R4 and R5 represent halogen, H or the like; R6 and R7 represent H, alkyl or the like; and m, n, p and q represent an integer of 0 to 3. In this connection, each group may have a substituent.
摘要翻译:本发明的目的是在侧链中产生具有螺环结构的新型吲唑衍生物,其可用作药物,并找到衍生物的新药理活性。 本发明化合物由通式[I]表示,具有优异的Rho激酶抑制活性。 在该式中,环X表示苯环或吡啶环; R 1和R 2表示卤素,H,OH,烷氧基,环烷氧基,芳氧基,烷基,环烷基等; R3表示卤素,H等; R4和R5表示卤素,H等; R6和R7代表H,烷基等; m,n,p和q表示0〜3的整数。就此而言,各基团可以具有取代基。
摘要:
A magnetic disc apparatus having a magnetic disc on which information is recorded, a magnetic head and a magnetic head supporting mechanism. The magnetic head supporting mechanism includes a slider having the magnetic head mounted thereon, a load beam having an arm mounting portion and a pivot, and a gimbal having a mounting portion on which the slider is mounted, two flexible finger portions spaced from the load beam and supporting the mounting portion so that the slider is rotatable with respect to the pivot, and a base end portion which is joined to the load beam. The load beam has two openings formed therein in proximity to the pivot which enable viewing of a back surface of the mounting portion which is opposite to a surface of the mounting portion of the gimbal on which the slider is mounted.