Chip element for micro chemical system and micro chemical system using the chip element
    1.
    发明申请
    Chip element for micro chemical system and micro chemical system using the chip element 审中-公开
    用于微化学系统的芯片元件和使用芯片元件的微量化学系统

    公开(公告)号:US20080124247A1

    公开(公告)日:2008-05-29

    申请号:US11983917

    申请日:2007-11-13

    IPC分类号: G01N21/64 G01N21/00

    摘要: There are provided a chip for micro chemical systems which can obviate the need of alignment at every measurement and can improve the measurement sensitivity and reduce the variation of measurement, and a micro chemical system using the chip. A thermal lens spectrometry system 10 comprises: a micro chemical chip 2 having a groove 1 into which a sample solution is injected; a rod lens 3 disposed on the micro chemical chip 2 at a predetermined spacing above the groove 1; a lens holder 9 disposed above the micro chemical chip 2; a securing section 4; an optical fiber 5; a ferrule 6 secured by the securing section 4 above the rod lens 3; a light source unit 7 connected to the optical fiber 5, and a detection device 8 disposed below the micro chemical chip 2. The securing section 4 comprises a seating 32 laid on the micro chemical chip 2, and a metal split sleeve 33 for fitting the ferrule 6 and the lens holder 9 at the outside thereof.

    摘要翻译: 提供了一种用于微量化学系统的芯片,可以消除每次测量时对准的需要,并且可以提高测量灵敏度并减少测量的变化,以及使用该芯片的微型化学系统。 热透镜分光系统10包括:微化学芯片2,其具有注入样品溶液的槽1; 棒状透镜3,以规定的间隔配置在微细化学品片2上, 设置在微化学芯片2上方的透镜架9; 固定部分4; 光纤5; 由杆状透镜3上方的固定部4固定的套圈6; 连接到光纤5的光源单元7和设置在微化学芯片2下方的检测装置8。 固定部分4包括放置在微化学芯片2上的座32和用于将套圈6和透镜保持器9装配在其外侧的金属分开套筒33。

    Fluorescence analysis optical multiplexer/demultiplexer, fluorescence analysis optical module, fluorescence analyzer, fluorescence/photothermal conversion spectroscopic analyzer, and fluorescence analysis chip

    公开(公告)号:US07304734B2

    公开(公告)日:2007-12-04

    申请号:US11329456

    申请日:2006-01-09

    IPC分类号: G01J3/30

    摘要: A fluorescence analysis optical multiplexer/demultiplexer, a fluorescence analysis optical module, a fluorescence analyzer, a fluorescence/photothermal conversion spectroscopic analyzer, and a fluorescence analysis chip, according to which LIF analysis can be carried out easily and with high sensitivity, and moreover photothermal conversion spectroscopic analysis can be carried out easily and simultaneously with the LIF analysis. A microchemical system 100 as the fluorescence analyzer is comprised of a fluorescence analysis optical module 100a, a probe 50 that condenses exciting light onto a sample solution in a channel 204 inside a fluorescence analysis chip 20, and a sample stage 21 on which the fluorescence analysis chip 20 is mounted. The fluorescence analysis optical module 100a is comprised of an exciting light source 53 that outputs exciting light of dominant wavelength λ1, a fluorescence analysis optical multiplexer/demultiplexer 56 for use in the fluorescence analyzer which analyzes fluorescence of dominant wavelength λ2 (λ2>λ1) emitted from the sample upon the sample being irradiated with the exciting light via the probe 50, a detector 54 that receives the fluorescence, an optical fiber 106 that connects the fluorescence analysis optical multiplexer/demultiplexer 56 to the exciting light source 53, an optical fiber 107 that connects the fluorescence analysis optical multiplexer/demultiplexer 56 to the probe 50, and an optical fiber 108 that connects the fluorescence analysis optical multiplexer/demultiplexer 56 to the detector 54. The channel 204 through which the sample solution is passed is coated with a reflective metal film 205.

    Photothermal conversion spectroscopic analysis method and microchemical system for implementing the method
    3.
    发明申请
    Photothermal conversion spectroscopic analysis method and microchemical system for implementing the method 审中-公开
    光热转换光谱分析方法和微观化学实验方法

    公开(公告)号:US20050259259A1

    公开(公告)日:2005-11-24

    申请号:US11132892

    申请日:2005-05-18

    CPC分类号: G01N21/171 G01N2021/1712

    摘要: A photothermal conversion spectroscopic analysis method which is capable of performing analysis, measurement and detection with high sensitivity. A sample flows in a channel. A exciting light and a detecting light are exited. A gradient refractive index rod lens converges the exited light and forms a focal point at a position in or close to the channel. Intensity of the exited light and passing through the channel are detected. A depth of the channel is not less than two time as large as a difference in distance between focal positions of the exciting light and the detecting light.

    摘要翻译: 一种能够以高灵敏度进行分析,测量和检测的光热转换光谱分析方法。 样品在通道中流动。 激发光和探测光退出。 梯度折射率棒状透镜会聚退出的光,并且在通道中或靠近通道的位置处形成焦点。 检测到退出的光并通过通道的强度。 通道的深度不小于激发光的焦点位置与检测光之间的距离差的两倍。

    Detection system and probe therefor
    4.
    发明授权
    Detection system and probe therefor 有权
    检测系统和探头

    公开(公告)号:US08063384B2

    公开(公告)日:2011-11-22

    申请号:US12438536

    申请日:2007-11-20

    IPC分类号: G01J1/58

    摘要: There is provided a detection system capable of simultaneously detecting a plurality of fluorescences or phosphorescences having different dominant wavelengths generated from a minute region and a probe therefor. A fluorescence detection system includes a probe having a lens and optical fibers and arranged on one end thereof. The probe receives excitation light with a dominant wavelength and excitation light with a dominant wavelength at one end of the lens and converges the excitation lights at the solution containing Cy3 and Cy5 in a channel inside a microchemical chip and the probe receives fluorescence with a dominant wavelength and fluorescence with a dominant wavelength at the other end of the lens and converges the fluorescences at the tips of the optical fibers.

    摘要翻译: 提供了能够同时检测由微小区域产生的具有不同主要波长的多个荧光或磷光的检测系统及其探针。 荧光检测系统包括具有透镜和光纤并且布置在其一端的探针。 探头接收具有主波长的激发光和在透镜一端具有主波长的激发光,并将激发光在含有Cy3和Cy5的溶液中收敛在微化学芯片内的通道内,并且探针接收具有主波长的荧光 和在透镜另一端具有主波长的荧光,并将荧光收敛在光纤的尖端处。

    DETECTION SYSTEM AND PROBE THEREFOR
    5.
    发明申请
    DETECTION SYSTEM AND PROBE THEREFOR 有权
    检测系统及其探测器

    公开(公告)号:US20100224793A1

    公开(公告)日:2010-09-09

    申请号:US12438536

    申请日:2007-11-20

    IPC分类号: G01N21/64 G02B6/32

    摘要: There is provided a detection system capable of simultaneously detecting a plurality of fluorescences or phosphorescences having different dominant wavelengths generated from a minute region and a probe therefor. A fluorescence detection system includes a probe having a lens and optical fibers and arranged on one end thereof. The probe receives excitation light with a dominant wavelength and excitation light with a dominant wavelength at one end of the lens and converges the excitation lights at the solution containing Cy3 and Cy5 in a channel inside a microchemical chip and the probe receives fluorescence with a dominant wavelength and fluorescence with a dominant wavelength at the other end of the lens and converges the fluorescences at the tips of the optical fibers.

    摘要翻译: 提供了能够同时检测由微小区域产生的具有不同主要波长的多个荧光或磷光的检测系统及其探针。 荧光检测系统包括具有透镜和光纤并且布置在其一端的探针。 探头接收具有主波长的激发光和在透镜一端具有主波长的激发光,并将激发光在含有Cy3和Cy5的溶液中收敛在微化学芯片内的通道内,并且探针接收具有主波长的荧光 和在透镜另一端具有主波长的荧光,并将荧光收敛在光纤的尖端处。

    Detection method, microchemical system using the detection method, signal detection method, thermal lens spectroscopic system, fluorescence detection system, signal detection apparatus, signal detection system, signal detection program, and storage medium
    6.
    发明申请
    Detection method, microchemical system using the detection method, signal detection method, thermal lens spectroscopic system, fluorescence detection system, signal detection apparatus, signal detection system, signal detection program, and storage medium 审中-公开
    检测方法,使用检测方法的微观化学系统,信号检测方法,热透镜光谱系统,荧光检测系统,信号检测装置,信号检测系统,信号检测程序和存储介质

    公开(公告)号:US20080030718A1

    公开(公告)日:2008-02-07

    申请号:US11881641

    申请日:2007-07-26

    IPC分类号: G01N21/00 G06F15/00

    摘要: A detection method that can measure a plurality of measured substances in a fluid test sample at the same time, easily perform qualitative analysis and quantitative analysis, and reduce measurement errors between excitation energies of the measured substances, and a microchemical system using the detection method. A probe light with a wavelength of 780 nm CW-oscillated from a probe light source 16 is irradiated on measured substances in a minute channel 1, excitation lights with wavelengths of 658 nm and 532 nm, respectively, are modulated into plurality of flashing excitation lights with frequencies 1 kHz and 1.2 kHz and a duty factor of 50% and irradiated on the measured substances in the minute channel 1, the probe light refracted by a thermal lens formed by the irradiated flashing excitation lights is detected with respect to individual frequency components at the same time, and a signal of the detected probe light is guided from a PD 21 to a PC 24 as a signal processing apparatus via an IV amplifier 22. The PC 24 carries out FFT processing to measure the intensity of the signal with respect to individual frequency components.

    摘要翻译: 可以同时测量流体试样中的多种测定物质的检测方法,容易进行定性分析和定量分析,并减少被测物质的激发能量之间的测量误差,以及使用该检测方法的微化学系统。 将从探测光源16振荡的波长为780nm的探测光照射在分钟通道1中的测量物质上,分别将波长为658nm和532nm的激发光调制到多个闪光激发光 以1kHz和1.2kHz的频率和50%的占空因数照射在微通道1中的测量物质上,通过由照射的闪光激发光形成的热透镜折射的探测光相对于各个频率分量被检测 同时,检测到的探测光的信号经由IV放大器22作为信号处理装置从PD 21引导到PC24。 PC24进行FFT处理,以测量相对于各个频率分量的信号的强度。

    Fluorescence analysis optical multiplexer/demultiplexer, fluorescence analysis optical module, fluorescence analyzer, fluorescence/photothermal conversion spectroscopic analyzer, and fluorescence analysis chip

    公开(公告)号:US20060109465A1

    公开(公告)日:2006-05-25

    申请号:US11329456

    申请日:2006-01-09

    IPC分类号: G01N21/64

    摘要: A fluorescence analysis optical multiplexer/demultiplexer, a fluorescence analysis optical module, a fluorescence analyzer, a fluorescence/photothermal conversion spectroscopic analyzer, and a fluorescence analysis chip, according to which LIF analysis can be carried out easily and with high sensitivity, and moreover photothermal conversion spectroscopic analysis can be carried out easily and simultaneously with the LIF analysis. A microchemical system 100 as the fluorescence analyzer is comprised of a fluorescence analysis optical module 100a, a probe 50 that condenses exciting light onto a sample solution in a channel 204 inside a fluorescence analysis chip 20, and a sample stage 21 on which the fluorescence analysis chip 20 is mounted. The fluorescence analysis optical module 100a is comprised of an exciting light source 53 that outputs exciting light of dominant wavelength λ1, a fluorescence analysis optical multiplexer/demultiplexer 56 for use in the fluorescence analyzer which analyzes fluorescence of dominant wavelength λ2 (λ2>λ1) emitted from the sample upon the sample being irradiated with the exciting light via the probe 50, a detector 54 that receives the fluorescence, an optical fiber 106 that connects the fluorescence analysis optical multiplexer/demultiplexer 56 to the exciting light source 53, an optical fiber 107 that connects the fluorescence analysis optical multiplexer/demultiplexer 56 to the probe 50, and an optical fiber 108 that connects the fluorescence analysis optical multiplexer/demultiplexer 56 to the detector 54. The channel 204 through which the sample solution is passed is coated with a reflective metal film 205.

    Electrical junction box
    10.
    发明授权
    Electrical junction box 有权
    电接线盒

    公开(公告)号:US07775807B2

    公开(公告)日:2010-08-17

    申请号:US12314412

    申请日:2008-12-10

    IPC分类号: H01R12/00

    摘要: An electrical junction box has a casing for housing a circuit board on which electrically conductive paths are formed. Fuse-receiving sections in an upper wall of the casing are adapted to receive a mating member. Receiving ribs inward from an inside of a side wall of the casing at a position below the fuse-receiving sections to receive water that enters the casing from the fuse-receiving sections, guide ribs project inward from an inside of the side wall provided with the receiving ribs and extend from end edges of the receiving ribs to guide the water that is received on the receiving ribs to a bottom wall of the casing. A bottom wall of the casing defines drain holes.

    摘要翻译: 电接线盒具有用于容纳其上形成导电路径的电路板的壳体。 壳体上壁中的保险丝容纳部适于接纳配合件。 在保险丝容纳部分下方的位置处,从壳体的侧壁的内部向内接收肋,以从熔丝容纳部接收进入壳体的水,引导肋从设置有熔融接收部的侧壁的内侧向内突出 接收肋并且从接收肋的端部边缘延伸,以将容纳在接收肋上的水引导到壳体的底壁。 壳体的底壁限定排水孔。