Adsorbent and method for adsorbing a chemokine in body fluid
    2.
    发明授权
    Adsorbent and method for adsorbing a chemokine in body fluid 失效
    吸附剂和吸收体液中趋化因子的方法

    公开(公告)号:US07279106B2

    公开(公告)日:2007-10-09

    申请号:US11067748

    申请日:2005-03-01

    IPC分类号: B01D15/00

    摘要: A device for body fluid purification, comprising a container having an inlet and an outlet for a fluid and a means for preventing an adsorbent from flowing out of the container and an adsorbent charged in the container, the adsorbent comprising a spherical hydrogel, the spherical hydrogel having an average particle size in a range of from about 460 to 600 μm and having a substantially uniform particle size and comprising an epoxidated cellulose having hexadecylamine immobilized thereon in an amount of 100 to 300 μmol per gram of dry weight of said epoxidated cellulose, and water, wherein the weight ratio of said epoxidated cellulose having hexadecylamine immobilized thereon to the water is 2:8.

    摘要翻译: 一种用于体液净化的装置,包括具有用于流体的入口和出口的容器和用于防止吸附剂从容器流出的装置和装入容器中的吸附剂,吸附剂包括球形水凝胶,球形水凝胶 平均粒度在约460-600μm范围内并且具有基本上均匀的粒度,并且其中固定有十六烷基胺的环氧化纤维素的量为每克干重所述环氧化纤维素为100至300μmol,以及 水,其中固定有十六烷基胺的所述环氧化纤维素与水的重量比为2:8。

    Method for removing a chemokine
    6.
    发明授权
    Method for removing a chemokine 失效
    去除趋化因子的方法

    公开(公告)号:US06559290B1

    公开(公告)日:2003-05-06

    申请号:US08819630

    申请日:1997-03-17

    IPC分类号: C07K1700

    CPC分类号: B01D15/00 C07K14/521

    摘要: An adsorbent for removing a chemokine except interleukin-8 in body fluid, which comprises a solid material having an anionic functional group, a method for efficiently removing a chemokine except interleukin-8 in body fluid, which comprises by bringing the above adsorbent into contact with body fluid containing the chemokine and an adsorber for removing a chemokine except for interleukin-8 using the above adsorbent.

    摘要翻译: 一种用于除去体液中除白介素-8之外的趋化因子的吸附剂,其包含具有阴离子官能团的固体材料,用于有效除去体液中白细胞介素-8的趋化因子的方法,其包括通过使上述吸附剂与 含有趋化因子的体液和除了使用上述吸附剂的白细胞介素-8以外的趋化因子的吸附器。

    Hollow yarn membrane used for blood purification and blood purifier
    9.
    发明授权
    Hollow yarn membrane used for blood purification and blood purifier 失效
    中空丝膜用于血液净化和血液净化器

    公开(公告)号:US6042783A

    公开(公告)日:2000-03-28

    申请号:US973243

    申请日:1998-02-03

    IPC分类号: D01F6/76 A61M1/14

    摘要: A polysulfone hollow fiber membrane for blood purification which has no danger that any component of the membrane dissolves out, and which can be used suitably or hemodialysis and blood filtration and remove selectively and efficiently low-molecular-weight proteins having molecular weight of 10,000 to 30,000 contained in blood, as well as a blood purifier which can be used suitably as a hemodialyzer, a filter for hemodiafiltration and a blood filter are provided. The hollow fiber membrane comprises a polysulfone resin, wherein there are slit-shaped micropores having an average width of 0.02 to 0.15 .mu.m on the inner surface thereof; there are micropores having an average pore size of 0.1 to 1 .mu.m on the outer surface thereof; the inside thereof has a sponge-like structure; there are no large voids having a diameter of more than 10 .mu.m on the inner and outer surface thereof and inside the membrane; water permeability thereof is 400 to 2,500 ml/m.sup.2 .multidot.hr.multidot.mmHg; and a permeation rato for the total proteins is 1% or less. The blood puifier contains the hollow fiber membrane put into a cylindrical housing which is equipped with a blood inlet and a blood outlet, and either a dialysate solution inlet and a dialysate solution outlet or a filtrate outlet.

    摘要翻译: PCT No.PCT / JP97 / 00924 Sec。 371日期1998年2月3日 102(e)日期1998年2月3日PCT 1997年3月21日PCT公布。 公开号WO97 / 34687 日期1997年9月25日一种用于血液净化的聚砜中空纤维膜,其没有膜的任何成分溶解的危险,并且可以适当地使用,或者可以使用血液透析和血液过滤,并且选择性和有效地除去具有分子的低分子量蛋白质 血液中含有10,000〜30,000份的重量,以及适合用作血液透析器的血液净化器,血液透析滤过滤器和血液过滤器。 中空纤维膜包括聚砜树脂,其中在其内表面上具有平均宽度为0.02至0.15μm的狭缝状微孔; 在其外表面上具有平均孔径为0.1-1μm的微孔; 其内部具有海绵状结构; 在其内表面和外表面以及膜内均不存在直径大于10μm的大空隙; 其透水性为400〜2500ml / m 2×hr×mmHg; 并且总蛋白质的渗透量为1%以下。 血液循环器包含放入装有血液入口和血液出口的圆柱形壳体中的中空纤维膜,以及透析液溶液入口和透析液溶液出口或滤液出口。