摘要:
The present invention is directed to a method of forming an immobilized chemical moiety, such as a trifunctional chemical moiety that includes membrane-anchoring functionalities, on a solid support for use in automated chemical synthesis of a recognition molecule. The invention is further directed to a method of easily and efficiently synthesizing chemical moieties such as those used for biosensor applications. The invention is further directed to a composition, i.e., a solid support having a trifunctional chemical moiety linked thereto, that can be readily and easily used to generate biological molecules for applications, such as biosensor applications.
摘要:
The present invention is directed to a method of forming an immobilized chemical moiety, such as a trifunctional chemical moiety that includes membrane-anchoring functionalities, on a solid support for use in automated chemical synthesis of a recognition molecule. The invention is further directed to a method of easily and efficiently synthesizing chemical moieties such as those used for biosensor applications. The invention is further directed to a composition, i.e., a solid support having a trifunctional chemical moiety linked thereto, that can be readily and easily used to generate biological molecules for applications, such as biosensor applications.
摘要:
A sensor for the detection of tetrameric multivalent neuraminidase within a sample is disclosed, where a positive detection indicates the presence of a target virus within the sample. Also disclosed is a trifunctional composition of matter including a trifunctional linker moiety with groups bonded thereto including (a) an alkyl chain adapted for attachment to a substrate, (b) a fluorescent moiety capable of generating a fluorescent signal, and (c) a recognition moiety having a spacer group of a defined length thereon, the recognition moiety capable of binding with tetrameric multivalent neuraminidase.
摘要:
The present invention provides a composite material including a substrate having an oxide surface, and, a continuous monolayer on the oxide surface, the monolayer including a silicon atom from a trifunctional alkyl/alkenyl/alkynyl silane group that attaches to the oxide surface, an alkyl/alkenyl/alkynyl portion of at least three carbon atoms, a polyalkylene glycol spacer group, and either a reactive site (e.g., a recognition ligand) or a site resistant to non-specific binding (e.g., a methoxy or the like) at the terminus of each modified SAM. The present invention further provides a sensor element, a sensor array and a method of sensing, each employing the composite material. Patterning is also provided together with backfilling to minimize non-specific binding.
摘要:
The present invention relates to compositions comprising certain active compounds which are suitable as repellents, and to their use for preventing an infection of humans or of animals by the infectious states of parasitic flatworms (platyhelminths).
摘要:
A method for decoding a data stream containing audio/video substreams and control substreams comprises buffering nodes having the possibility to buffer multiple data packets in the same buffer. This may be achieved by having separate parameters for the allocated buffer size and any stored packet. Thus, not only multiple packets may be stored in the buffering node, but also such node may exist while its buffer is empty, so that the node may be reused later. This is particularly useful for buffering and selectively accessing multiple audio packets in MPEG-4 audio nodes or sound nodes.
摘要:
A cutlery holder for positionably retaining a plurality of cutlery items in either a horizontal orientation or in an inclined orientation. The cutlery holder includes a body portion having a plurality of slots formed therein for receiving blade portions of cutlery items and a support stand connected to the body portion. The support stand has a first position for supporting the body portion such that the slots extend in a horizontal orientation and a second position for supporting the body portion such that the slots extend in an inclined orientation.
摘要:
A method and an apparatus for creating a data block (Error Correction Code Block) comprising a plurality of data sectors, which data block is provided with parity information, and a method and an apparatus for recovering data sectors from a data block provided with parity information. A method for encoding or decoding data streams, respectively, which has a reduced memory requirement and manages with two encoders or decoders, respectively, and an encoding or decoding unit, respectively, for implementing the method, are proposed. In the case of a method for creating an ECC block comprising a plurality of data sectors, the data sectors being buffer-stored in the form of a block with a plurality of rows in a memory organized in the form of rows and columns and being provided with parity information, successively received blocks of data sectors are written row by row alternately to the rows or columns, respectively, of the memory.
摘要:
The invention relates to a joining connection of at least one exhaust-gas-carrying pipe of an internal-combustion engine having a fastening flange which is inserted in its duct and, on its opening edge situated inside the duct, is welded to the duct wall of the flange, and to a process for its manufacture. In order to provide in a simple manner an automating capacity of the manufacture of the joining connection which is reliable with respect to the process, at least one support projection is constructed in an axially position-defined manner on the duct wall. The support projection projects into the duct and the pipe rests directly on the support projection in the plug-in position in the axial direction. The interior wall of the pipe ends flush with the end edge or projects radially beyond it toward the inside.
摘要:
Novel compounds of the formula ##STR1## where the phenyl ring can also contain a nitrogen atom instead of a CH group, R.sub.1 is C.sub.2 -C.sub.6 -alkenyl, C.sub.2 -C.sub.6 -alkynyl, hydroxy, C.sub.1 -C.sub.6 -alkoxy, C.sub.3 -C.sub.6 -alkenyloxy, C.sub.3 -C.sub.6 -alkynyloxy, C.sub.2 -C.sub.6 -alkanoyloxy, benzoyloxy, morpholinocarbonyloxy, C.sub.1 -C.sub.6 -alkyloxycarbonyloxy, C.sub.1 -C.sub.6 -alkylaminocarbonyloxy, C.sub.1 -C.sub.6 -dialkylaminocarbonyloxy or the group -Alk-A, where Alk represents C.sub.1 -C.sub.6 -alkyl, C.sub.2 -C.sub.6 -hydroxyalkyl or C.sub.3 -C.sub.6 -cycloalkyl and the symbol A represents hydrogen or other substituents.R.sub.2, R.sub.3 and R.sub.4 represent various substituents, where R.sub.1 may also be hydrogen, when R.sub.2 is the group ##STR2## and R.sub.5 represents phenyl, C.sub.1 -C.sub.4 -alkoxyphenyl or diphenylmethyl and R.sub.3 and R.sub.4 are hydrogen and their salts. The compounds provide anti-allergic, anti-asthmatic, anxiolytic and hypotensive effects.