公开(公告)号：US10221211B2

公开(公告)日：2019-03-05

申请号：US15025152

申请日：2014-09-26

Applicant: KANEKA CORPORATION

Inventor： Takahiro Okubo ,  Yoshikazu Kawai ,  Masaru Hirano ,  Fuminori Konoike ,  Keiichi Karasugi ,  Tatsuya Honda

IPC: B01D15/38 ,  C07K1/22 ,  B01J20/24 ,  C08B1/08 ,  C08B15/08 ,  C08B15/10 ,  C08B3/06 ,  C08B15/00 ,  C08B16/00 ,  C08L1/02 ,  C08L1/04 ,  C08L1/12 ,  B01J20/286 ,  B01J20/32 ,  B01J20/28 ,  C08J3/16 ,  B01J20/26 ,  B01J20/285 ,  B01J20/30 ,  C07K16/00 ,  C08J9/00

Abstract: A process for producing porous cellulose beads of the present invention is characterized by comprising the steps of: a) mixing an alkali aqueous solution and cellulose to prepare cellulose micro dispersion at low temperature, b) adding water to the cellulose micro dispersion to prepare cellulose slurry, and d) bringing the cellulose slurry into contact with coagulation solvent. A carrier for ligand immobilization of the present invention is characterized by being by shrinking polysaccharide porous beads not less than 10% by a shrinkage rate defined by the following formula, and crosslinking the polysaccharide porous beads: Shrinkage rate (%)=(1−V2/V1)×100 (wherein, V1 indicates the gel volume of polysaccharide porous beads before shrinkage, and V2 indicates the gel volume of polysaccharide porous beads after shrinkage).

公开(公告)号：US10457705B2

公开(公告)日：2019-10-29

申请号：US16227688

申请日：2018-12-20

Applicant: KANEKA CORPORATION

Inventor： Takahiro Okubo ,  Yoshikazu Kawai ,  Masaru Hirano ,  Fuminori Konoike ,  Keiichi Karasugi ,  Tatsuya Honda

IPC: B01J20/24 ,  C07K1/22 ,  B01J20/30 ,  C08B1/08 ,  C08B15/08 ,  C08B15/10 ,  C08B3/06 ,  C07K16/00 ,  B01J20/26 ,  B01J20/285 ,  C08J3/16 ,  B01J20/28 ,  B01J20/32 ,  B01J20/286 ,  B01D15/38 ,  C08L1/12 ,  C08L1/04 ,  C08L1/02 ,  C08B16/00 ,  C08B15/00 ,  C08J9/00

Abstract: A carrier for ligand immobilization obtained by shrinking polysaccharide porous beads not less than 10% by a shrinkage rate defined by the following formula, and crosslinking the polysaccharide porous beads: Shrinkage rate (%)=(1−V2/V1)×100 (wherein, V1 indicates the gel volume of polysaccharide porous beads before shrinkage, and V2 indicates the gel volume of polysaccharide porous beads after shrinkage).

公开(公告)号：US20180056271A1

公开(公告)日：2018-03-01

申请号：US15783248

申请日：2017-10-13

Applicant: Kaneka Corporation

Inventor： Yoshikazu Kawai ,  Asuka Hayashi ,  Masaru Hirano ,  Yosuke Kawahata

IPC: B01J20/24 ,  B01D15/38 ,  B01J20/30 ,  B01J20/28 ,  B01J20/285 ,  C08J9/28 ,  B01J20/281

CPC classification number: B01J20/24 ,  B01D15/08 ,  B01D15/3809 ,  B01J20/28016 ,  B01J20/285 ,  B01J20/30 ,  B01J20/3085 ,  B01J2220/52 ,  C08J9/28 ,  G01N30/482 ,  G01N30/88

Abstract: A method for producing porous cellulose beads includes preparing a fine cellulose dispersion by mixing a low temperature alkaline aqueous solution and cellulose; preparing a mixed liquid by adding a crosslinking agent to the fine cellulose dispersion; preparing an emulsion by dispersing the mixed liquid in a dispersion medium; and contacting the emulsion with a coagulating solvent.