公开(公告)号：US09365501B2

公开(公告)日：2016-06-14

申请号：US14397352

申请日：2013-04-30

Applicant: KOWA COMPANY, LTD.

Inventor： Masahiro Tamura ,  Takahide Oshita

IPC: C07C245/08 ,  A61L27/16 ,  C08F220/68 ,  C09B29/12 ,  C08F220/60 ,  A61L27/50 ,  C09B29/01 ,  C09B69/10

CPC classification number: C07C245/08 ,  A61F2/16 ,  A61F2002/16965 ,  A61L27/16 ,  A61L27/50 ,  A61L2430/16 ,  C08F220/00 ,  C08F220/60 ,  C08F220/68 ,  C09B29/0003 ,  C09B29/12 ,  C09B69/106 ,  C08L33/26

Abstract: A polymerizable UV-absorbing colorant monomer is provided, which is excellent in stability under alkaline conditions and which is available for a useful material polymer for an intraocular lens. A compound, which is represented by the following general formula (1), is used as a polymerizable UV-absorbing monomer available for a material polymer for an intraocular lens: (in the general formula (1), R1 is a hydrogen atom, a hydroxy group, a carboxy group, an alkyl group having 1 to 8 carbon atoms, an alkoxy group having 1 to 8 carbon atoms, a sulfonic acid group, or a benzyloxy group, R2 is a hydrogen atom, a hydroxy group, or an alkoxy group having 1 to 4 carbon atoms, and R3 is represented by the following formula (2)): (in the general formula (2), R4 is a hydrogen atom or a methyl group, and R5 is a single bond or an alkylene group having 1 to 4 carbon atoms which may have a substituent or substituents.)

Abstract translation: 提供了一种可聚合的UV吸收着色剂单体，其在碱性条件下的稳定性优异，并且可用于眼内透镜的有用材料聚合物。 使用由以下通式（1）表示的化合物作为可用于眼内透镜材料聚合物的可聚合的UV吸收单体：（在通式（1）中，R 1是氢原子， 羟基，羧基，碳原子数1〜8的烷基，碳原子数1〜8的烷氧基，磺酸基或苄氧基，R2是氢原子，羟基或烷氧基 具有1至4个碳原子的基团，R 3由下式（2）表示）：（在通式（2）中，R 4是氢原子或甲基，R 5是单键或亚烷基 具有1至4个可具有取代基的碳原子。）

公开(公告)号：US20150094439A1

公开(公告)日：2015-04-02

申请号：US14397352

申请日：2013-04-30

Applicant: KOWA COMPANY, LTD.

Inventor： Masahiro Tamura ,  Takahide Oshita

IPC: C07C245/08 ,  A61L27/16 ,  C08F220/68

CPC classification number: C07C245/08 ,  A61F2/16 ,  A61F2002/16965 ,  A61L27/16 ,  A61L27/50 ,  A61L2430/16 ,  C08F220/00 ,  C08F220/60 ,  C08F220/68 ,  C09B29/0003 ,  C09B29/12 ,  C09B69/106 ,  C08L33/26

Abstract: A polymerizable UV-absorbing colorant monomer is provided, which is excellent in stability under alkaline conditions and which is available for a useful material polymer for an intraocular lens. A compound, which is represented by the following general formula (1), is used as a polymerizable UV-absorbing monomer available for a material polymer for an intraocular lens: (in the general formula (1), R1 is a hydrogen atom, a hydroxy group, a carboxy group, an alkyl group having 1 to 8 carbon atoms, an alkoxy group having 1 to 8 carbon atoms, a sulfonic acid group, or a benzyloxy group, R2 is a hydrogen atom, a hydroxy group, or an alkoxy group having 1 to 4 carbon atoms, and R3 is represented by the following formula (2)): (in the general formula (2), R4 is a hydrogen atom or a methyl group, and R5 is a single bond or an alkylene group having 1 to 4 carbon atoms which may have a substituent or substituents.)

Abstract translation: 提供了一种可聚合的UV吸收着色剂单体，其在碱性条件下的稳定性优异，并且可用于眼内透镜的有用材料聚合物。 使用由以下通式（1）表示的化合物作为可用于眼内透镜材料聚合物的可聚合的UV吸收单体：（在通式（1）中，R 1是氢原子， 羟基，羧基，碳原子数1〜8的烷基，碳原子数1〜8的烷氧基，磺酸基或苄氧基，R2是氢原子，羟基或烷氧基 具有1至4个碳原子的基团，R 3由下式（2）表示）：（在通式（2）中，R 4是氢原子或甲基，R 5是单键或亚烷基 具有1至4个可具有取代基的碳原子。）