利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

16 条记录 (耗时 0.052 秒)

    Use of cyanine dyes for the diagnosis of disease associated with angiogenesis
    7.
    发明申请
    Use of cyanine dyes for the diagnosis of disease associated with angiogenesis 审中-公开
    花青染料用于诊断与血管生成有关的疾病

    公开(公告)号：US20060039863A1

    公开(公告)日：2006-02-23

    申请号：US11185025

    申请日：2005-07-20

    申请人： Michael Schirner ,  Kai Licha ,  Peter Hauff ,  Christin Perlitz

    发明人： Michael Schirner ,  Kai Licha ,  Peter Hauff ,  Christin Perlitz

    IPC分类号： A61K49/00 ,  C12Q1/68 ,  G01N33/574

    CPC分类号： A61K49/0058 ,  A61K49/0032 ,  G01N33/533 ,  G01N33/574 ,  G01N33/582

    摘要： This invention relates to the use of conjugates of cyanine dyes with an angiogenesis specific binding component preferably with an EB-D fibronectin specific binding component for the diagnosis of micrometastasis and small proliferative lesions, in particular primary tumors, precancerosis, dysplasia, metaplasia, inflammatory lesions, e.g. psoriasis, psoriatic arthritis and/or rheumatoid arthritis, endometriotic lesions, and ocular diseases associated with angiogenesis.

    摘要翻译： 本发明涉及花青染料与血管生成特异性结合组分的缀合物与EB-D纤连蛋白特异性结合组分的用途，用于诊断微转移和小增殖性病变，特别是原发性肿瘤，癌前病变，发育不良，化生，炎性病变 ，例如 牛皮癣，银屑病关节炎和/或类风湿性关节炎，子宫内膜异位病变和与血管发生相关的眼部疾病。

    Device and process for direct quantitative in vitro determination of a substance that is contained in a sample
    8.
    发明申请
    Device and process for direct quantitative in vitro determination of a substance that is contained in a sample 审中-公开
    用于直接定量体外测定样品中所含物质的装置和方法

    公开(公告)号：US20050037402A1

    公开(公告)日：2005-02-17

    申请号：US10887228

    申请日：2004-07-09

    申请人： Michael Schirner ,  Kai Licha

    发明人： Michael Schirner ,  Kai Licha

    IPC分类号： C12Q1/68 ,  G01N33/50 ,  G01N33/53 ,  G01N33/532 ,  G01N33/542

    CPC分类号： G01N33/542

    摘要： This invention relates to a device and a process for direct quantitative in vitro determination of a substance that is contained in a sample. The device according to the invention comprises agents, immobilized on a surface, for detecting substances, a free substance-emitter conjugate, and agents, immobilized on a surface, for detecting the emitter. The emitter of the device that is used comprises a portion that reacts with a change in the emission properties in an interaction with the agent for detecting the emitter. By means of the device according to the invention, substances that are selected from antigens, such as proteins, peptides, nucleic acids, oligonucleotides, blood components, serum components, lipids, pharmaceutical agents and compounds of low molecular weight or, in another design, substance-detecting agents, such as, for example, antibodies or fragments thereof, can be determined directly quantitatively, in, e.g., whole-blood samples.

    摘要翻译： 本发明涉及用于直接定量体外测定样品中所含物质的装置和方法。 根据本发明的装置包括固定在表面上用于检测物质的游离物质 - 发射体结合物和固定在表面上的用于检测发射体的试剂。 使用的装置的发射器包括与用于检测发射器的试剂的相互作用中与发射性质的变化反应的部分。 通过根据本发明的装置，选自抗原的物质，例如蛋白质，肽，核酸，寡核苷酸，血液成分，血清成分，脂质，药物和低分子量的化合物，或者在另一种设计中， 物质检测剂，例如抗体或其片段，可直接在例如全血样品中定量测定。