摘要:
A compound having the formula: in which R1, R2, R3, T, W, m, x, and y are defined as in the specification. Also disclosed is a method of treating enterovirus infection by using a compound described above.
摘要:
This invention features, among others, a pyrazolopyrimidine compound of formula (A): A is (CH2)q—CHRaRb; each of R1 and R2, independently, is hydrogen, halogen, cyano, nitro, or alkyl; or R1 and R2 taken together is (CH2)r; each of R3 and R4, independently, is hydrogen, halogen, cyano, nitro, or alkyl; each of R5, Ra, and Rb, independently, is aryl, aralkyl, or heteroaryl, optionally substituted with halogen, cyano, nitro, alkyl, aryl, aralkyl, heteroaryl, OR, O(O)CR, C(O)R, C(O)OR, C(O)NRR′, SR, S(O)R, S(O)OR, NRR′, NR(O)CR′, NRC(O)OR′, or NRC(O)NR′R″; each of m, n, o, p, and r, independently, is 0 or 1, and q is 0, 1, or 2; in which each of R, R′, and R″, independently, is hydrogen or alkyl, provided that the sum of m, n, o, and p is 1, 2, 3, or 4.
摘要翻译:本发明特别地包括式(A)的吡唑并嘧啶化合物:A是(CH 2)q-CHR a R b; R 1和R 2各自独立地是氢,卤素,氰基,硝基或烷基; 或者R 1和R 2一起是(CH 2)r; R 3和R 4各自独立地是氢,卤素,氰基,硝基或烷基; 氰基,硝基,烷基,芳基,芳烷基,杂芳基,OR,O(O)CR,R 3,R 3和R 4各自独立地是芳基,芳烷基或杂芳基, C(O)OR,NR(O)OR,C(O)NRR',SR,S(O)R,S(O)OR,NRR' 或NRC(O)NR'R“; m,n,o,p和r各自独立地为0或1,q为0,1或2; 其中R,R'和R“各自独立地是氢或烷基,条件是m,n,o和p的和为1,2,3或4。
摘要:
Imidazol-4-one or imidazole-4-thione compounds of formula (I): wherein X, R1, R2, R3, R4, R5, and R6 are defined herein. Also disclosed is a method for treating a cannabinoid receptor-mediated disorder with these compounds.
摘要:
This invention relates to selenophene compounds of formula (I) shown below. Each variable in formula (I) is defined in the specification. These compounds can be used to treat cannabinoid-receptor mediated disorders.
摘要:
This invention relates to pyrazole compounds of formula (I) shown below: Each variable in formula (I) is defined in the specification. These compounds can be used to treat cannabinoid-receptor mediated disorders.
摘要:
This invention relates to selenophene compounds of formula (I) shown below. Each variable in formula (I) is defined in the specification. These compounds can be used to treat cannabinoid-receptor mediated disorders.
摘要:
This invention relates to a method for treating inflammatory diseases or immune diseases, developmental or degenerative diseases, or tissue injuries. The method includes administering to a subject in need thereof an effective amount of one or more compounds of the following formula. Each variable in this formula is defined in the specification.
摘要:
Imidazol-4-one or imidazole-4-thione compounds of formula (I): wherein X, R1, R2, R3, R4, R5, and R6 are defined herein. Also disclosed is a method for treating a cannabinoid receptor-mediated disorder with these compounds.
摘要:
A compound of formula (I): in which A, R1, R2, and R3 are as defined herein. Also disclosed are (1) a pharmaceutical composition containing such a compound, and (2) a method for treating a cannabinoid receptor-mediated disorder using such a compound.
摘要:
This invention relates to a method for treating inflammatory diseases or immune diseases, developmental or degenerative diseases, or tissue injuries. The method includes administering to a subject in need thereof an effective amount of one or more compounds of the following formula. Each variable in this formula is defined in the specification.