公开(公告)号：US20060135718A1

公开(公告)日：2006-06-22

申请号：US11015399

申请日：2004-12-17

申请人： Karl Benson ,  G. Bommarito ,  Albert Everaerts ,  Brinda Lakshmi ,  Charles Leir ,  George Moore ,  Lang Nguyen ,  Rahul Shah ,  Peter Stark

发明人： Karl Benson ,  G. Bommarito ,  Albert Everaerts ,  Brinda Lakshmi ,  Charles Leir ,  George Moore ,  Lang Nguyen ,  Rahul Shah ,  Peter Stark

IPC分类号： C08F228/02

CPC分类号： C08F220/18 ,  C08F220/34 ,  C08F220/38

摘要： Soluble polymers and methods for the preparation thereof, wherein the polymers of the present invention have pendant acylsulfonamide amine-reactive groups that can be used for the capture of amine containing materials.

公开(公告)号：US20070190662A1

公开(公告)日：2007-08-16

申请号：US10596953

申请日：2004-12-17

申请人： John Baetzold ,  Karl Benson ,  G. Bommarito ,  Michael Daniels ,  Albert Everaerts ,  Peggy-Jean Flanigan ,  M. Free ,  Cary Kipke ,  Brinda Lakshmi ,  Charles Leir ,  George Moore ,  Lang Nguyen ,  Rahul Shah ,  Peter Stark

发明人： John Baetzold ,  Karl Benson ,  G. Bommarito ,  Michael Daniels ,  Albert Everaerts ,  Peggy-Jean Flanigan ,  M. Free ,  Cary Kipke ,  Brinda Lakshmi ,  Charles Leir ,  George Moore ,  Lang Nguyen ,  Rahul Shah ,  Peter Stark

IPC分类号： G01N21/75

CPC分类号： G01N29/022 ,  B01L3/502723 ,  B01L3/502746 ,  B01L2200/04 ,  B01L2200/0684 ,  B01L2200/10 ,  B01L2200/16 ,  B01L2300/06 ,  B01L2300/0663 ,  B01L2300/0672 ,  B01L2300/069 ,  B01L2300/161 ,  B01L2400/0406 ,  B01L2400/0478 ,  B01L2400/0683 ,  B01L2400/086 ,  B01L2400/088 ,  C07C311/51 ,  C07D207/46 ,  C07D275/06 ,  G01N29/2462 ,  G01N33/54373 ,  G01N2291/0255 ,  G01N2291/0256 ,  G01N2291/02881 ,  G01N2291/0422 ,  G01N2291/0423 ,  G01N2291/0426 ,  G01N2291/0427 ,  Y10T436/141111

摘要： Acoustic sensors, preferably surface acoustic wave sensors, and more preferably shear horizontal surface acoustic wave sensors that include soluble mixed with oligomers and/or polymers formed from such monomers), or multifunctional compounds, for example, that can function as either waveguide materials, immobilization materials for secondary capture agents (e.g., antibodies), or both.

摘要翻译： 声学传感器，优选表面声波传感器，更优选剪切水平表面声波传感器，其包括可溶性聚合物，单体（任选地与由这些单体形成的低聚物和/或聚合物混合）或多官能化合物，例如可以起到 波导材料，二次捕获剂（例如，抗体）的固定化材料或两者。

公开(公告)号：US20070045622A1

公开(公告)日：2007-03-01

申请号：US11553822

申请日：2006-10-27

申请人： Karl Benson ,  Moses David ,  Cary Kipke ,  Brinda Lakshmi ,  Charles Leir ,  George Moore ,  Rahul Shah

发明人： Karl Benson ,  Moses David ,  Cary Kipke ,  Brinda Lakshmi ,  Charles Leir ,  George Moore ,  Rahul Shah

IPC分类号： H01L29/08 ,  H01L35/24

CPC分类号： C07D275/06 ,  B82Y30/00 ,  C07C311/51 ,  C07D207/46 ,  G01N33/54353

摘要： Compounds having two reactive functional groups are described that can be used to provide a connector group between a substrate and an amine-containing material. The first reactive functional group can be used to provide attachment to a surface of a substrate. The second reactive functional group is a N-sulfonylaminocarbonyl group that can be reacted with an amine-containing material, particularly a primary aliphatic amine, to form a carbonylimino-containing connector group. The invention also provides articles and methods for immobilizing amine-containing materials to a substrate.

摘要翻译： 描述了具有两个反应性官能团的化合物，其可用于在基材和含胺材料之间提供连接基团。 第一反应性官能团可用于提供与基底表面的附着。 第二反应性官能团是可与含胺材料，特别是伯脂肪族胺反应形成含羰基亚氨基的连接基团的N-磺酰基氨基羰基。 本发明还提供了将含胺材料固定在基材上的制品和方法。

公开(公告)号：US20060135783A1

公开(公告)日：2006-06-22

申请号：US11015543

申请日：2004-12-17

申请人： Karl Benson ,  Cary Kipke ,  Brinda Lakshmi ,  Charles Leir ,  George Moore ,  Rahul Shah

发明人： Karl Benson ,  Cary Kipke ,  Brinda Lakshmi ,  Charles Leir ,  George Moore ,  Rahul Shah

IPC分类号： C07D275/02 ,  C07D209/90 ,  C07D209/48 ,  C07D207/40

CPC分类号： C07D207/404 ,  C07D209/94 ,  C07D275/06

摘要： Multifunctional compounds having acylsulfonamide amine-reactive groups are described that can be used for the capture of amine containing materials.

摘要翻译： 描述了具有酰基磺酰胺胺反应性基团的多官能化合物，其可用于捕获含胺材料。

公开(公告)号：US20070154937A1

公开(公告)日：2007-07-05

申请号：US11686018

申请日：2007-03-14

申请人： Karl Benson ,  Moses David ,  Cary Kipke ,  Brinda Lakshmi ,  Charles Leir ,  George Moore ,  Rahul Shah

发明人： Karl Benson ,  Moses David ,  Cary Kipke ,  Brinda Lakshmi ,  Charles Leir ,  George Moore ,  Rahul Shah

IPC分类号： C12Q1/68 ,  G01N33/53 ,  C12M1/34 ,  C07D209/90 ,  C07D209/48

CPC分类号： C07D207/404 ,  B82Y30/00 ,  C07D209/48 ,  C07D209/76 ,  C07D211/88 ,  C07D403/12 ,  C07D471/08 ,  Y10T428/31616 ,  Y10T428/31623

摘要： Compounds having two reactive functional groups are described that can be used as a tethering compound to immobilize an amine-containing material to a substrate. The first reactive functional group can be used to provide attachment to a surface of a substrate. The second reactive functional group is a N-sulfonyldicarboximide group that can be reacted with an amine-containing material, particularly a primary aliphatic amine, to form a connector group between the substrate and the amine-containing material. The invention also provides articles and methods for immobilizing amine-containing materials to a substrate.

摘要翻译： 描述了具有两个反应性官能团的化合物，其可以用作系链化合物以将含胺材料固定在基材上。 第一反应性官能团可用于提供与基底表面的附着。 第二反应性官能团是可与含胺材料，特别是伯脂肪族胺反应的N-磺酰基二亚胺酰亚胺基团，以在基材和含胺材料之间形成连接基团。 本发明还提供了将含胺材料固定在基材上的制品和方法。

公开(公告)号：US20050112672A1

公开(公告)日：2005-05-26

申请号：US10987522

申请日：2004-11-12

申请人： Karl Benson ,  Moses David ,  Cary Kipke ,  Brinda Lakshmi ,  Charles Leir ,  George Moore ,  Rahul Shah

发明人： Karl Benson ,  Moses David ,  Cary Kipke ,  Brinda Lakshmi ,  Charles Leir ,  George Moore ,  Rahul Shah

IPC分类号： C07C311/51 ,  C07D207/46 ,  C07D275/06 ,  G01N33/543 ,  C12Q1/68 ,  C12M1/34

CPC分类号： G01N33/54353 ,  B82Y30/00 ,  B82Y40/00 ,  C07C311/51 ,  C07D207/46 ,  C07D275/06

摘要： Compounds having two reactive functional groups are described that can be used to provide a connector group between a substrate and an amine-containing material. The first reactive functional group can be used to provide attachment to a surface of a substrate. The second reactive functional group is a N-sulfonylaminocarbonyl group that can be reacted with an amine-containing material, particularly a primary aliphatic amine, to form a carbonylimino-containing connector group. The invention also provides articles and methods for immobilizing amine-containing materials to a substrate.

摘要翻译： 描述了具有两个反应性官能团的化合物，其可用于在基材和含胺材料之间提供连接基团。 第一反应性官能团可用于提供与基底表面的附着。 第二反应性官能团是可与含胺材料，特别是伯脂肪族胺反应形成含羰基亚氨基的连接基团的N-磺酰基氨基羰基。 本发明还提供了将含胺材料固定在基材上的制品和方法。

公开(公告)号：US20050227076A1

公开(公告)日：2005-10-13

申请号：US10987075

申请日：2004-11-12

申请人： Karl Benson ,  Moses David ,  Cary Kipke ,  Brinda Lakshmi ,  Charles Leir ,  George Moore ,  Rahul Shah

发明人： Karl Benson ,  Moses David ,  Cary Kipke ,  Brinda Lakshmi ,  Charles Leir ,  George Moore ,  Rahul Shah

IPC分类号： B32B27/00 ,  C07D207/00 ,  C07D207/40 ,  C07D207/404 ,  C07D209/48 ,  C07D209/76 ,  C07D211/88 ,  C07D275/06 ,  C07D403/12 ,  C07D471/08

CPC分类号： C07D207/404 ,  B82Y30/00 ,  B82Y40/00 ,  C07D209/48 ,  C07D209/76 ,  C07D211/88 ,  C07D275/06 ,  C07D403/12 ,  C07D471/08 ,  G01N2291/0256 ,  G01N2291/0422 ,  G01N2291/0423 ,  G01N2291/0427 ,  Y10T428/2982 ,  Y10T428/2998 ,  Y10T428/31616 ,  Y10T428/31623 ,  Y10T428/31721 ,  Y10T428/31786

摘要： Compounds having two reactive functional groups are described that can be used as a tethering compound to immobilize an amine-containing material to a substrate. The first reactive functional group can be used to provide attachment to a surface of a substrate. The second reactive functional group is a N-sulfonyldicarboximide group that can be reacted with an amine-containing material, particularly a primary aliphatic amine, to form a connector group between the substrate and the amine-containing material. The invention also provides articles and methods for immobilizing amine-containing materials to a substrate.

摘要翻译： 描述了具有两个反应性官能团的化合物，其可以用作系链化合物以将含胺材料固定在基材上。 第一反应性官能团可用于提供与基底表面的附着。 第二反应性官能团是可与含胺材料，特别是伯脂肪族胺反应的N-磺酰基二亚胺酰亚胺基团，以在基材和含胺材料之间形成连接基团。 本发明还提供了将含胺材料固定在基材上的制品和方法。

公开(公告)号：US20050107615A1

公开(公告)日：2005-05-19

申请号：US10713174

申请日：2003-11-14

申请人： Karl Benson ,  Moses David ,  Cary Kipke ,  Brinda Lakshmi ,  Charles Leir ,  George Moore ,  Rahul Shah

发明人： Karl Benson ,  Moses David ,  Cary Kipke ,  Brinda Lakshmi ,  Charles Leir ,  George Moore ,  Rahul Shah

IPC分类号： C07C311/51 ,  C07D207/46 ,  C07D275/06 ,  G01N33/543 ,  C07F9/02 ,  C07C39/54 ,  C07D43/02

CPC分类号： C07D275/06 ,  B82Y30/00 ,  C07C311/51 ,  C07D207/46 ,  G01N33/54353

摘要： Compounds having two reactive functional groups are described that can be used to provide a connector group between a substrate and an amine-containing material. The first reactive functional group can be used to provide attachment to a surface of a substrate. The second reactive functional group is a N-sulfonylaminocarbonyl group that can be reacted with an amine-containing material, particularly a primary aliphatic amine, to form a carbonylimino-containing connector group. The invention also provides articles and methods for immobilizing amine-containing materials to a substrate.

公开(公告)号：US20050106709A1

公开(公告)日：2005-05-19

申请号：US10714053

申请日：2003-11-14

申请人： Karl Benson ,  Moses David ,  Cary Kipke ,  Brinda Lakshmi ,  Charles Leir ,  George Moore ,  Rahul Shah

发明人： Karl Benson ,  Moses David ,  Cary Kipke ,  Brinda Lakshmi ,  Charles Leir ,  George Moore ,  Rahul Shah

IPC分类号： C07D207/40 ,  C07D207/404 ,  C07D209/48 ,  C07D209/76 ,  C07D211/88 ,  C07D403/12 ,  C07D471/08 ,  C12M1/34 ,  A61L2/00 ,  B05D3/00 ,  C07D249/18 ,  C07D23/02

CPC分类号： C07D207/404 ,  B82Y30/00 ,  C07D209/48 ,  C07D209/76 ,  C07D211/88 ,  C07D403/12 ,  C07D471/08 ,  Y10T428/31616 ,  Y10T428/31623

摘要： Compounds having two reactive functional groups are described that can be used as a tethering compound to immobilize an amine-containing material to a substrate. The first reactive functional group can be used to provide attachment to a surface of a substrate. The second reactive functional group is a N-sulfonyldicarboximide group that can be reacted with an amine-containing material, particularly a primary aliphatic amine, to form a connector group between the substrate and the amine-containing material. The invention also provides articles and methods for immobilizing amine-containing materials to a substrate.

公开(公告)号：US20070078244A1

公开(公告)日：2007-04-05

申请号：US11240239

申请日：2005-09-30

申请人： Rahul Shah ,  Karl Benson ,  Charles Leir ,  George Moore

发明人： Rahul Shah ,  Karl Benson ,  Charles Leir ,  George Moore

IPC分类号： C08F226/06 ,  C07D209/56 ,  C07D209/48 ,  C07D207/46

CPC分类号： C08G73/0213 ,  C07D209/48 ,  Y10T428/31855

摘要： Crosslinked polymeric materials are described that contain pendant amine capture groups. The amine capture groups include N-sulfonyldicarboximide groups that can react with amine-containing materials by a ring opening reaction. Reaction mixtures used to prepare the crosslinked polymeric materials, articles containing the crosslinked polymeric materials, methods of making articles, and methods of immobilizing an amine-containing material are also described.