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公开(公告)号：US07740795B2
公开(公告)日：2010-06-22
申请号：US11179385
申请日：2005-07-12
IPC分类号： B22F3/11
CPC分类号： A61F2/30767 , A61B17/68 , A61B17/86 , A61F2/3094 , A61F2/32 , A61F2/34 , A61F2/36 , A61F2/3662 , A61F2/4657 , A61F2002/30011 , A61F2002/3092 , A61F2002/30929 , A61F2002/30968 , A61F2002/3098 , A61F2002/3611 , A61F2002/4631 , A61F2250/0023 , A61F2310/00023 , A61F2310/00029 , A61F2310/00095 , A61F2310/00131 , A61F2310/00407 , A61F2310/00413 , A61F2310/00491 , A61F2310/00544 , A61L27/30 , A61L27/40 , A61L27/56 , B22F3/1137 , B22F3/114 , B22F7/004 , B22F2999/00 , Y10T428/12479
摘要： The invention relates to implantable medical devices, particularly, to porous structures for such devices. In one aspect, the invention provides a porous metal scaffold comprising a porous metal network having pores defined by metal webs, the metal webs covered with at least one layer of metal particles bonded to the metal webs. In other aspects, the invention provides methods of forming porous scaffolds. In one such aspect, the method includes providing a polymer foam; forming a skin of biocompatible metal on the polymer foam by low temperature arc vapor deposition; and heating the polymer foam and the metal skin above the decomposition temperature of the polymer foam in an inert gas atmosphere; thereby the polymer foam decomposes producing a green metal foam. In yet other aspects, the invention provides methods of improving stability of porous scaffolds.
摘要翻译： 本发明涉及可植入医疗装置，特别涉及这种装置的多孔结构。 在一个方面，本发明提供了一种多孔金属支架，其包括多孔金属网，其具有由金属网限定的孔，金属网覆盖有至少一层结合到金属网的金属颗粒。 在其它方面，本发明提供了形成多孔支架的方法。 在一个这样的方面，该方法包括提供聚合物泡沫; 通过低温电弧气相沉积在聚合物泡沫上形成生物相容性金属的皮肤; 并且在惰性气体气氛中将聚合物泡沫和金属表皮加热至聚合物泡沫的分解温度以上; 从而聚合物泡沫分解产生绿色金属泡沫。 在另一方面，本发明提供了改善多孔支架稳定性的方法。
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公开(公告)号：US07648524B2
公开(公告)日：2010-01-19
申请号：US11318172
申请日：2005-12-23
IPC分类号： A61B17/84
CPC分类号： A61B17/686 , A61F2/0811 , A61F2002/0829 , A61F2002/0864 , A61F2002/0882 , B33Y80/00
摘要： An anchor for fixing a ligament or tendon replacement in a bore formed in a bone has two parts. A first partially cylindrical part has a semi-circular bore therethrough extending along an axis. The bore tapers conically inwardly with respect to the axis from a larger radius at a first end to a smaller radius at second end. The outer surface of the partially cylindrical part is spaced at a constant radius from the axis between the first and second ends. The first and second parts have side walls formed between the bore and the outer surface which walls extend along a plane which forms an angle with respect to the central axis. When the two parts are engaged along their side wails and slide with respect to the axis the outer diameter of the two parts enlarges.
摘要翻译： 用于在形成在骨中的孔中固定韧带或腱置换的锚具有两部分。 第一部分圆柱形部分具有沿轴线延伸的半圆形孔。 孔从第一端的较大半径到第二端较小的半径相对于轴线呈锥形向内锥形。 部分圆柱形部分的外表面与第一和第二端之间的轴线间隔开恒定的半径。 第一和第二部分具有形成在孔和外表面之间的侧壁，该壁沿着相对于中心轴线形成一角度的平面延伸。 当这两个部件沿着它们的侧壁接合并且相对于轴线滑动时，两个部件的外径扩大。
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3.发明授权Surface modified unit cell lattice structures for optimized secure freeform fabrication 有权表面改性单元晶格结构，用于优化的安全自由形状制造公开(公告)号：US09180010B2
公开(公告)日：2015-11-10
申请号：US13618218
申请日：2012-09-14
申请人： Nicholas Nai Guang Dong , Matthew P. Poggie , Robert W. Klein , Eric Jones , Christopher J. Sutcliffe , Joe Robinson , Dan Jones , Lewis Mullen , Robin Stamp
发明人： Nicholas Nai Guang Dong , Matthew P. Poggie , Robert W. Klein , Eric Jones , Christopher J. Sutcliffe , Joe Robinson , Dan Jones , Lewis Mullen , Robin Stamp
CPC分类号： G06F17/50 , A61F2/28 , A61F2/30767 , A61F2/30942 , A61F2002/30952 , B22F3/1055 , B23K15/0086 , B23K26/342 , B33Y80/00 , Y02P10/295
摘要： Aspects of the present disclosure relate generally to preparing models of three-dimensional structures. In particular, a model of a three-dimensional structure constructed of porous geometries is prepared. A component file including a porous CAD volume having a boundary is prepared. A space including the porous CAD volume is populated with unit cells. The unit cells are populated with porous geometries having a plurality of struts having nodes on each end. The space is populated with at least one elongated fixation element extending beyond the boundary to produce an interlocking feature enabling assembly or engagement with a mating structure.
摘要翻译： 本公开的方面通常涉及制备三维结构的模型。 特别地，制备由多孔几何形状构成的三维结构的模型。 准备包括具有边界的多孔CAD体积的组件文件。 包含多孔CAD体积的空间填充有单位单元。 单元电池填充有多孔几何形状，其具有在每个端部上具有节点的多个支柱。 该空间内装有延伸超过边界的至少一个细长的固定元件以产生能够与配合结构组装或接合的互锁特征。
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4.发明申请SURFACE MODIFIED UNIT CELL LATTICE STRUCTURES FOR OPTIMIZED SECURE FREEFORM FABRICATION 有权表面改性单元格式结构优化安全FREEFORM制造公开(公告)号：US20130268085A1
公开(公告)日：2013-10-10
申请号：US13618218
申请日：2012-09-14
申请人： Nicholas Nai Guang Dong , Matthew P. Poggie , Robert W. Klein , Eric Jones , Christopher J. Sutcliffe , Joe Robinson , Dan Jones , Lewis Mullen , Robin Stamp
发明人： Nicholas Nai Guang Dong , Matthew P. Poggie , Robert W. Klein , Eric Jones , Christopher J. Sutcliffe , Joe Robinson , Dan Jones , Lewis Mullen , Robin Stamp
IPC分类号： A61F2/28
CPC分类号： G06F17/50 , A61F2/28 , A61F2/30767 , A61F2/30942 , A61F2002/30952 , B22F3/1055 , B23K15/0086 , B23K26/342 , B33Y80/00 , Y02P10/295
摘要： Aspects of the present disclosure relate generally to preparing models of three-dimensional structures. In particular, a model of a three-dimensional structure constructed of porous geometries is prepared. A component file including a porous CAD volume having a boundary is prepared. A space including the porous CAD volume is populated with unit cells. The unit cells are populated with porous geometries having a plurality of struts having nodes on each end. The space is populated with at least one elongated fixation element extending beyond the boundary to produce an interlocking feature enabling assembly or engagement with a mating structure.
摘要翻译： 本公开的方面通常涉及制备三维结构的模型。 特别地，制备由多孔几何形状构成的三维结构的模型。 准备包括具有边界的多孔CAD体积的组件文件。 包含多孔CAD体积的空间填充有单位单元。 单位单元填充有多孔几何形状，其具有在每个端部上具有节点的多个支柱。 该空间内装有延伸超过边界的至少一个细长的固定元件以产生能够与配合结构组装或接合的互锁特征。
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公开(公告)号：US07578851B2
公开(公告)日：2009-08-25
申请号：US11317229
申请日：2005-12-23
IPC分类号： A61F2/32
CPC分类号： A61F2/30767 , A61B17/86 , A61F2/3094 , A61F2/32 , A61F2/34 , A61F2/36 , A61F2/3662 , A61F2/367 , A61F2/3672 , A61F2/3676 , A61F2002/30011 , A61F2002/30322 , A61F2002/30324 , A61F2002/30769 , A61F2002/30822 , A61F2002/30838 , A61F2002/3092 , A61F2002/30929 , A61F2002/30968 , A61F2002/3403 , A61F2002/3611 , A61F2002/3631 , A61F2002/368 , A61F2250/0023 , A61F2250/0026 , A61F2250/0036 , A61F2310/00011 , A61F2310/00017 , A61F2310/00023 , A61F2310/00029 , A61F2310/00095 , A61F2310/00131 , A61F2310/00179 , A61F2310/00401 , A61F2310/00407 , A61F2310/00413 , A61F2310/00491 , A61F2310/00544 , B22F3/1137 , B22F3/1146 , B22F2998/10 , B22F2999/00 , B33Y80/00 , C23C26/00 , C23C28/00 , C23C28/026 , C23C28/028 , B22F2207/13
摘要： An implantable medical device includes a porous metal foam or foam-like structure having pores defined by metal struts or webs wherein the porous structure has directionally controlled pore characteristics. The pore characteristics controlled include one or more of the metal structure porosity, pore size, pore shape, pore size distribution and strut thickness. The pore characteristics may vary in one or more directions throughout the structure. Preferably the pore characteristics are controlled to match the porous metal structure to various mechanical and biological requirements of different regions of the structure in order to optimize aspects of the implants performance and may vary not only over the surface of the porous structure but through the depth of the porous structure. The thickness of the porous metal structure may also be modified to establish a thickness profile that optimizes mechanical and biological requirements of the implants performance. Acetabular cup embodiments of the invention are described. Various methods of manufacturing implants having directionally controlled pore characteristics are described.
摘要翻译： 可植入医疗装置包括具有由金属支柱或腹板限定的孔的多孔金属泡沫或泡沫状结构，其中多孔结构具有定向控制的孔特性。 受控的孔隙特性包括金属结构孔隙率，孔径，孔隙形状，孔径分布和支柱厚度中的一种或多种。 孔结构特征可以在整个结构中的一个或多个方向上变化。 优选地，孔特征被控制以使多孔金属结构与结构的不同区域的各种机械和生物学要求相匹配，以优化植入物性能的方面，并且可以不仅在多孔结构的表面上而且通过多孔结构的深度 多孔结构。 多孔金属结构的厚度也可以被修改以建立优化植入物性能的机械和生物学要求的厚度分布。 描述本发明的髋臼杯实施例。 描述了具有定向控制孔特性的植入物的各种制造方法。
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公开(公告)号：US08900303B2
公开(公告)日：2014-12-02
申请号：US13544172
申请日：2012-07-09
CPC分类号： A61F2/34 , A61B17/1746 , A61B17/68 , A61B17/846 , A61B17/866 , A61F2/30734 , A61F2/30749 , A61F2002/30011 , A61F2002/30112 , A61F2002/30205 , A61F2002/30433 , A61F2002/30736 , A61F2002/30822 , A61F2002/3092 , A61F2002/30962 , A61F2002/3412
摘要： A method of reinforcing the bone in an acetabulum for receiving a prosthetic acetabular implant includes preparing a surface of the acetabulum to receive an acetabular implant. At least one porous generally cylindrical bone reinforcement element is provided. At least one bore is drilled in an area of the acetabulum receiving the prosthetic acetabular implant for receiving at least one and preferably more reinforcement elements in the form of cylindrical pilings. The cylindrical porous bone reinforcement element is inserted in the bore such that an exposed surface of the porous bone reinforcement element is adjacent the surface of the acetabulum. The acetabular implant is then implanted with an outer surface of the acetabular implant supported by the reinforcement members.
摘要翻译： 在用于接受假体髋臼植入物的髋臼中加强骨的方法包括制备髋臼的表面以接收髋臼植入物。 提供至少一个多孔的大体上圆柱形的骨加强元件。 在接受假体髋臼植入物的髋臼的区域中钻出至少一个孔，用于容纳至少一个并且优选地以圆柱形桩的形式的增强元件。 圆柱形多孔骨加强元件插入孔中，使得多孔骨加强元件的暴露表面邻近髋臼表面。 然后将髋臼植入物植入由加强构件支撑的髋臼植入物的外表面。
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公开(公告)号：US20140012390A1
公开(公告)日：2014-01-09
申请号：US13544172
申请日：2012-07-09
CPC分类号： A61F2/34 , A61B17/1746 , A61B17/68 , A61B17/846 , A61B17/866 , A61F2/30734 , A61F2/30749 , A61F2002/30011 , A61F2002/30112 , A61F2002/30205 , A61F2002/30433 , A61F2002/30736 , A61F2002/30822 , A61F2002/3092 , A61F2002/30962 , A61F2002/3412
摘要： A method of reinforcing the bone in an acetabulum for receiving a prosthetic acetabular implant includes preparing a surface of the acetabulum to receive an acetabular implant. At least one porous generally cylindrical bone reinforcement element is provided. At least one bore is drilled in an area of the acetabulum receiving the prosthetic acetabular implant for receiving at least one and preferably more reinforcement elements in the form of cylindrical pilings. The cylindrical porous bone reinforcement element is inserted in the bore such that an exposed surface of the porous bone reinforcement element is adjacent the surface of the acetabulum. The acetabular implant is then implanted with an outer surface of the acetabular implant supported by the reinforcement members.
摘要翻译： 在用于接受假体髋臼植入物的髋臼中加强骨的方法包括制备髋臼的表面以接收髋臼植入物。 提供至少一个多孔的大体上圆柱形的骨加强元件。 在接受假体髋臼植入物的髋臼的区域中钻出至少一个孔，用于容纳至少一个并且优选地以圆柱形桩的形式的增强元件。 圆柱形多孔骨加强元件插入孔中，使得多孔骨加强元件的暴露表面邻近髋臼表面。 然后将髋臼植入物植入由加强构件支撑的髋臼植入物的外表面。
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