PROTEIN REFOLDING AGENT AND REFOLDING METHOD
    3.
    发明申请
    PROTEIN REFOLDING AGENT AND REFOLDING METHOD 有权
    蛋白质引发剂和重建方法

    公开(公告)号:US20090111971A1

    公开(公告)日:2009-04-30

    申请号:US12063443

    申请日:2006-08-11

    CPC分类号: C07K1/1136

    摘要: A refolding agent and refolding method which make it possible to produce high-purity proteins in high productivity. The refolding agent includes a phosphorus-containing compound (A) and an oxycarbonyl group-containing compound (B). The refolding method includes the step of treating the unfolded protein with the refolding agent. As the compound (A), there may be mentioned at least one species selected from inorganic phosphoric acids, alkyl phosphate esters, sugar phosphate esters, and salts of these, and as the compound (B), there may be mentioned at least one species selected from formic acid, acetic acid, propionic acid, lactic acid, tartaric acid, and salts of these.

    摘要翻译: 可以以高生产率制造高纯度蛋白质的再折叠剂和重折叠方法。 再折叠剂包括含磷化合物(A)和含氧基羰基的化合物(B)。 重折叠方法包括用折叠剂处理未折叠蛋白质的步骤。 作为化合物(A),可以提及选自无机磷酸,烷基磷酸酯,糖磷酸酯及其盐中的至少一种,作为化合物(B),可以提及至少一种 选自甲酸,乙酸,丙酸,乳酸,酒石酸及其盐。

    Method of producing open-cell foamed articles of cross-linked polyolefins
    4.
    发明授权
    Method of producing open-cell foamed articles of cross-linked polyolefins 失效
    交联聚烯烃开孔发泡制品的制备方法

    公开(公告)号:US4435346A

    公开(公告)日:1984-03-06

    申请号:US357682

    申请日:1982-03-12

    摘要: An open-cell foamed article of a cross-linked polyolefin having a high open-cell ratio and a high degree of expansion is produced by a method which comprises the steps of preparing a foamable and cross-linkable polyolefin composition, forming the composition into a desired shape maintaining its gel percent at zero, decomposing the cross-linking agent and blowing agent concurrently by heating the composition under atmospheric pressure in such conditions that the peak of the ratio of the degree of cross-linking to the degree of decomposition of the blowing agent is not more than 20 and exerting a mechanical deformation to the resulting polyolefin foam to rupture the cell membranes.

    摘要翻译: 通过包括以下步骤的方法制备具有高开孔率和高膨胀膨胀率的交联聚烯烃的开孔泡沫制品,所述方法包括制备可发泡和可交联的聚烯烃组合物,将组合物形成为 所需形状保持其凝胶百分比为零,通过在大气压下加热组合物同时分解交联剂和发泡剂,使得交联度与吹塑分解程度的峰值 试剂不超过20,并对所得的聚烯烃泡沫塑料进行机械变形以使细胞膜破裂。

    Protein refolding agent and refolding method
    5.
    发明授权
    Protein refolding agent and refolding method 有权
    蛋白质再折叠剂和重折叠法

    公开(公告)号:US07858661B2

    公开(公告)日:2010-12-28

    申请号:US12063443

    申请日:2006-08-11

    IPC分类号: A61K31/19 C07C61/12

    CPC分类号: C07K1/1136

    摘要: A refolding agent and refolding method which make it possible to produce high-purity proteins in high productivity. The refolding agent includes a phosphorus-containing compound (A) and an oxycarbonyl group-containing compound (B). The refolding method includes the step of treating the unfolded protein with the refolding agent. As the compound (A), there may be mentioned at least one species selected from inorganic phosphoric acids, alkyl phosphate esters, sugar phosphate esters, and salts of these, and as the compound (B), there may be mentioned at least one species selected from formic acid, acetic acid, propionic acid, lactic acid, tartaric acid, and salts of these.

    摘要翻译: 可以以高生产率制造高纯度蛋白质的再折叠剂和重折叠方法。 再折叠剂包括含磷化合物(A)和含氧基羰基的化合物(B)。 重折叠方法包括用折叠剂处理未折叠蛋白质的步骤。 作为化合物(A),可以提及选自无机磷酸,烷基磷酸酯,糖磷酸酯及其盐中的至少一种,作为化合物(B),可以提及至少一种 选自甲酸,乙酸,丙酸,乳酸,酒石酸及其盐。

    Support assembly for radiators and air conditioning condensors
    6.
    发明授权
    Support assembly for radiators and air conditioning condensors 失效
    散热器和空调冷凝器的支撑组件

    公开(公告)号:US4141426A

    公开(公告)日:1979-02-27

    申请号:US791572

    申请日:1977-04-27

    摘要: A support assembly for radiators and air conditioning condensors for motor vehicles which includes a support frame having a central opening and a center brace of roughly crank shaped cross section provided in the center of the frame and vertically cutting across the opening therein. The crank shaped cross section is formed by two parallel attachment faces which project laterally with respect to the opening in opposite directions and a member connecting the two faces. The two attachment faces are arranged and configured such that they respectively serve as a mount for an inboard side of the radiator and an inboard side of the condensor and such that the attachment face for the radiator overlaps the condensor and the attachment face for the condensor overlaps the radiator.

    摘要翻译: 一种用于机动车辆的散热器和空调冷凝器的支撑组件,其包括具有中心开口的支撑框架和设置在框架中心并且横跨其中的开口的垂直切割的大致曲柄形横截面的中心支架。 曲柄形横截面由两个平行的连接面形成,两个平行的连接面在相反方向上相对于开口横向突出,并且连接两个面的构件。 两个附接面被布置和构造成使得它们分别用作用于散热器的内侧的安装件和冷凝器的内侧,并且用于散热器的附接面与冷凝器重叠,并且用于冷凝器重叠的附接面 散热器。

    Bacteriolytic agent
    7.
    发明授权
    Bacteriolytic agent 有权
    细菌分解剂

    公开(公告)号:US08003369B2

    公开(公告)日:2011-08-23

    申请号:US12092610

    申请日:2006-11-06

    IPC分类号: C12N1/06

    CPC分类号: C12N1/06 C11D1/62

    摘要: The present invention is a bacteriolytic agent containing a cationic surfactant (A) of which a counteranion is an acid having a pKa (25° C.) of 0 to 10. As the counterion, a carboxylate anion is preferable. As the cationic surfactant (A), a quaternary ammonium salt-type surfactant is preferable. Examples of the useful substance include a protein, an amino acid, a nucleic acid, an antibiotic, sugars or vitamins.The bacteriolytic agent of the present invention is excellent in a bacteriolytic power in a step of extracting a useful substance from a microorganism (useful substance producing bacterium etc.). In addition, denaturation of the useful substance during the step is small.

    摘要翻译: 本发明是含有阳离子性表面活性剂(A)的溶菌剂,其中抗衡阴离子是pKa(25℃)为0〜10的酸。作为抗衡离子,优选羧酸根阴离子。 作为阳离子性表面活性剂(A),优选季铵盐型表面活性剂。 有用物质的实例包括蛋白质,氨基酸,核酸,抗生素,糖或维生素。 本发明的溶菌剂在从微生物(有用的生物细菌等)中提取有用物质的步骤中的溶菌能力优异。 此外,步骤期间有用物质的变性小。

    BACTERIOLYTIC AGENT
    8.
    发明申请
    BACTERIOLYTIC AGENT 有权
    微生物剂

    公开(公告)号:US20090143569A1

    公开(公告)日:2009-06-04

    申请号:US12092610

    申请日:2006-11-06

    CPC分类号: C12N1/06 C11D1/62

    摘要: The present invention is a bacteriolytic agent containing a cationic surfactant (A) of which a counteranion is an acid having a pKa (25° C.) of 0 to 10. As the counterion, a carboxylate anion is preferable. As the cationic surfactant (A), a quaternary ammonium salt-type surfactant is preferable. Examples of the useful substance include a protein, an amino acid, a nucleic acid, an antibiotic, sugars or vitamins.The bacteriolytic agent of the present invention is excellent in a bacteriolytic power in a step of extracting a useful substance from a microorganism (useful substance producing bacterium etc.). In addition, denaturation of the useful substance during the step is small.

    摘要翻译: 本发明是含有阳离子性表面活性剂(A)的溶菌剂,其中抗衡阴离子是pKa(25℃)为0〜10的酸。作为抗衡离子,优选羧酸根阴离子。 作为阳离子性表面活性剂(A),优选季铵盐型表面活性剂。 有用物质的实例包括蛋白质,氨基酸,核酸,抗生素,糖或维生素。 本发明的溶菌剂在从微生物(有用的生物细菌等)中提取有用物质的步骤中的溶菌能力优异。 此外,步骤期间有用物质的变性小。

    Electroconductive cross-linked polyolefin foam and method for
manufacture thereof
    9.
    发明授权
    Electroconductive cross-linked polyolefin foam and method for manufacture thereof 失效
    导电交联聚烯烃泡沫及其制造方法

    公开(公告)号:US4519963A

    公开(公告)日:1985-05-28

    申请号:US495406

    申请日:1983-05-17

    摘要: An electroconductive cross-linked polyolefin foam having electric resistance of not more than 100 M.OMEGA. and comprising uniform minute cells and proving useful for the production of IC cases, etc. is provided by a method which comprises kneading 100 parts by weight of a polyolefin, 10 to 30 parts by weight of carbon particles, and suitable amounts of a foaming agent and a cross-linking agent and heating the resultant cross-linkable and foamable composition under atmospheric pressure thereby allowing the composition to be cross-linked and foamed without being abruptly foamed or expanded or by a method which comprises heating the aforementioned cross-linkable and foamable composition in a metal mold under pressure to a temperature at which the foaming agent is not substantially decomposed thereby cross-linking the composition and then heating the resultant cross-linked foamable composition under atmospheric pressure thereby allowing the composition to be foamed without being abruptly foamed or expanded. The aforementioned cross-linking may be effected by irradiation of the composition with an electron beam.

    摘要翻译: 通过包括捏合100重量份的聚烯烃的方法,提供具有不超过100M欧米茄并且包含均匀的微细胞并证明用于制造IC盒等的导电交联聚烯烃泡沫体, 10〜30重量份的碳颗粒和适量的发泡剂和交联剂,并在大气压下加热所得的可交联和可发泡组合物,从而允许组合物交联和发泡而不突然 发泡或膨胀的方法,或通过将金属模具中的上述可交联和可发泡组合物在压力下加热至发泡剂基本上不分解的温度,从而交联组合物,然后加热所得交联剂 可发泡组合物,从而允许组合物发泡而不会突然发生 amed或扩大。 上述交联可以通过用电子束照射组合物来实现。