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17 条记录 (耗时 0.038 秒)

    Triazine derivatives, and pharmaceutical compositions comprising the same
    5.
    发明授权
    Triazine derivatives, and pharmaceutical compositions comprising the same 失效
    三嗪衍生物和包含其的药物组合物

    公开(公告)号：US4618610A

    公开(公告)日：1986-10-21

    申请号：US603173

    申请日：1984-04-23

    申请人： Tsutomu Teraji ,  Youichi Shiokawa ,  Kazuo Okumura ,  Yoshinari Sato

    发明人： Tsutomu Teraji ,  Youichi Shiokawa ,  Kazuo Okumura ,  Yoshinari Sato

    IPC分类号： A61K31/53 ,  A61P1/04 ,  A61P7/02 ,  A61P9/12 ,  C07D253/06

    CPC分类号： C07D253/06

    摘要： New triazine derivatives represented by the formula: ##STR1## wherein R.sup.1 is hydrogen or halogen;R.sup.2 is a hydroxy, protected hydroxy, amino, cyano, mercapto, lower alkylthio, arylthio, sulfamoyl, lower alkylsulfonylamino, lower alkylureido, arylureido, lower alkyl-thioureido, aryl-thioureido, lower alkenoylamino, lower alkoxycarbonylamino, lower alkoxy(thiocarbonyl)thio, or cyclic or acyclic alkanoylamino in which the cyclic and acyclic alkanoylamino group may have a substituent selected from lower alkoxy, aryl, hydroxyaryl and protected hydroxyaryl; andX is O or S;and pharmaceutically acceptable salt thereof, which are useful in the treatment of hypertension, thrombosis and ulcer in human beings and animals.

    摘要翻译： 由下式表示的新的三嗪衍生物：其中R 1是氢或卤素; R2是羟基，保护的羟基，氨基，氰基，巯基，低级烷硫基，芳硫基，氨磺酰基，低级烷基磺酰基氨基，低级烷基脲基，芳基脲基，低级烷基 - 硫脲基，芳基 - 硫脲基，低级烯酰基氨基，低级烷氧基羰基氨基，低级烷氧基（硫代羰基） 或环状或无环烷酰氨基，其中环状和非环状烷酰基氨基可以具有选自低级烷氧基，芳基，羟基芳基和被保护的羟基芳基的取代基; X为O或S; 和其药学上可接受的盐，其可用于治疗人和动物中的高血压，血栓形成和溃疡。

    Coated body having excellent thermal radiation property used for members of electronic device
    6.
    发明申请
    Coated body having excellent thermal radiation property used for members of electronic device 有权
    具有优异的热辐射性能的涂覆体用于电子设备的构件

    公开(公告)号：US20050163983A1

    公开(公告)日：2005-07-28

    申请号：US10762460

    申请日：2004-01-23

    申请人： Takeshi Watase ,  Yasuo Hirano ,  Kazuo Okumura ,  Tetsuya Yamamoto

    发明人： Takeshi Watase ,  Yasuo Hirano ,  Kazuo Okumura ,  Tetsuya Yamamoto

    IPC分类号： B32B7/02 ,  C08K3/04 ,  C08K3/08 ,  C09D5/24 ,  C09D167/00 ,  G06F1/18

    CPC分类号： G06F1/182 ,  C08K3/04 ,  C08K3/08 ,  C09D5/24 ,  C09D167/00 ,  Y10T428/24868 ,  Y10T428/24942 ,  Y10T428/2495

    摘要： Disclosed is a coated body for members of an electronic device, comprising a substrate covered, on the surface side and back side thereof, with respective thermal radiative coatings having thermal radiation property, wherein a difference ΔT1 (=T1B−T1A) between Temperature T1A, at Position T1, of the coated body used as a sample and Temperature T1B, at Position T2, of the substrate not covered with a coating used as another sample is 1.5° C. or greater, said temperatures being measured using a thermal radiation property evaluating apparatus illustrated in FIG. 1; and whereby satisfying its essential properties (maintenance of air tightness to block water or dust and reduction in size and weight), while reducing the temperature inside of the members of an electronic device (thermal radiation property).

    摘要翻译： 公开了一种用于电子设备的构件的涂覆体，包括在其表面侧和背面上覆盖具有热辐射性质的各自的热辐射涂层的基底，其中差值ΔT1（= T 1 B < 在用作样品的涂覆体的T 1位置的温度T 1＆lt; A＆gt;之间的温度T 1＆lt; B＆lt; 在未被用作另一样品的涂层覆盖的基板的位置T 2处的面积为1.5℃或更大，所述温度使用图1所示的热辐射性能评估装置进行测量。 1; 并且由此满足其基本特性（保持气密性以阻止水或灰尘并减小尺寸和重量），同时降低电子设备的构件内部的温度（热辐射性）。

    (+)-5-isopropyl 3-methyl 2-cyano-6 methyl-4-(3-nitrophenyl)-1, 4-dihydropyridine-3, 5-dicarboxylate
    7.
    发明授权
    (+)-5-isopropyl 3-methyl 2-cyano-6 methyl-4-(3-nitrophenyl)-1, 4-dihydropyridine-3, 5-dicarboxylate 失效
    （+） - 5-异丙基3-甲基2-氰基-6-甲基-4-（3-硝基苯基）-1,4-二氢吡啶-3,5-二羧酸酯

    公开(公告)号：US5508413A

    公开(公告)日：1996-04-16

    申请号：US662507

    申请日：1991-03-22

    申请人： Youichi Shiokawa ,  Kazuo Okumura

    发明人： Youichi Shiokawa ,  Kazuo Okumura

    IPC分类号： C07D213/84 ,  C07D213/80

    CPC分类号： C07D213/84

    摘要： This invention relates to novel (+)-5-isopropyl 3-methyl 2-cyano-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate.More particularly, it relates to novel (+)-5-isopropyl 3-methyl 2-cyano-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate, which has pharmacological activities such as hypotensive and vasodilating activities, to a pharmaceutical composition comprising the same and to a method for treating hypertension, cardiovascular diseases, and the like.Accordingly, one object of this invention is to provide novel (+)-5-isopropyl 3-methyl 2-cyano-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate, which is of use for treating hyperxtension, cardiovascular diseases, and the like.

    摘要翻译： 本发明涉及2-氰基-6-甲基-4-（3-硝基苯基）-1,4-二氢吡啶-3,5-二羧酸的新的（+） - 5-异丙基-3-甲酯。 更具体地说，它涉及2-（3-硝基苯基）-1,4-二氢吡啶-3,5-二羧酸的新的（+） - 5-异丙基3-氰基-6-甲基-4-（3-硝基苯基）-1,4-二氢吡啶-3,5-二羧酸酯，其药理活性如 作为降血压和血管舒张活性，涉及包含其的药物组合物和治疗高血压，心血管疾病等的方法。 因此，本发明的一个目的是提供新的（+） - 5-异丙基2-氰基-6-甲基-4-（3-硝基苯基）-1,4-二氢吡啶-3,5-二甲酸3-甲酯，其中 用于治疗高血压，心血管疾病等。

    Coated body having excellent thermal radiation property used for members of electronic device
    10.
    发明授权
    Coated body having excellent thermal radiation property used for members of electronic device 有权
    具有优异的热辐射性能的涂覆体用于电子设备的构件

    公开(公告)号：US07279218B2

    公开(公告)日：2007-10-09

    申请号：US10762460

    申请日：2004-01-23

    申请人： Takeshi Watase ,  Yasuo Hirano ,  Kazuo Okumura ,  Tetsuya Yamamoto

    发明人： Takeshi Watase ,  Yasuo Hirano ,  Kazuo Okumura ,  Tetsuya Yamamoto

    IPC分类号： B32B7/02 ,  B32B27/32

    CPC分类号： G06F1/182 ,  C08K3/04 ,  C08K3/08 ,  C09D5/24 ,  C09D167/00 ,  Y10T428/24868 ,  Y10T428/24942 ,  Y10T428/2495

    摘要： Disclosed is a coated body for members of an electronic device, comprising a substrate covered, on the surface side and back side thereof, with respective thermal radiative coatings having thermal radiation property, wherein a difference ΔT1 (=T1B−T1A) between Temperature T1A, at Position T1, of the coated body used as a sample and Temperature T1B, at Position T2, of the substrate not covered with a coating used as another sample is 1.5° C. or greater, said temperatures being measured using a thermal radiation property evaluating apparatus illustrated in FIG. 1; and whereby satisfying its essential properties (maintenance of air tightness to block water or dust and reduction in size and weight), while reducing the temperature inside of the members of an electronic device (thermal radiation property).

    摘要翻译： 公开了一种用于电子设备的构件的涂覆体，包括在其表面侧和背面上覆盖具有热辐射性质的各自的热辐射涂层的基底，其中差值ΔT1（= T 1 B < 在用作样品的涂覆体的T 1位置的温度T 1＆lt; A＆gt;之间的温度T 1＆lt; B＆lt; 在未被用作另一样品的涂层覆盖的基板的位置T 2处的面积为1.5℃或更大，所述温度使用图1所示的热辐射性能评估装置进行测量。 1; 并且由此满足其基本特性（保持气密性以阻止水或灰尘并减小尺寸和重量），同时降低电子设备的构件内部的温度（热辐射性）。