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公开(公告)号：US20140314859A1
公开(公告)日：2014-10-23
申请号：US14238616
申请日：2012-08-03
申请人： Keietsu Abe , Kazuyoshi Kawakami , Tadafumi Ajiri , Manabu Fukumoto , Seiichi Takami , Takanari Togashi , Kimihide Muragaki , Toru Takahashi
发明人： Keietsu Abe , Kazuyoshi Kawakami , Tadafumi Ajiri , Manabu Fukumoto , Seiichi Takami , Takanari Togashi , Kimihide Muragaki , Toru Takahashi
CPC分类号： A61K9/1676 , A61K38/168 , A61K49/1863 , B22F1/0018 , B22F1/0062 , B82Y5/00 , B82Y30/00 , B82Y40/00 , C01G49/08 , C01P2004/62 , C01P2006/12 , C09C1/24
摘要： It has been found that modification of surfaces of nanoparticles with a RolA protein decreases an immunostimulation activity of the nanoparticles on myeloid dendritic cells and also decreases phagocytosis of the nanoparticles by macrophages. The present invention provides nanoparticles being modified with a biological molecule and having an immune-response evasion function.
摘要翻译： 已经发现用RolA蛋白修饰纳米颗粒的表面降低了纳米颗粒在骨髓树突状细胞上的免疫刺激活性，并且还降低了巨噬细胞对纳米颗粒的吞噬作用。 本发明提供了用生物分子修饰并具有免疫应答逃避功能的纳米颗粒。
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公开(公告)号：US09387175B2
公开(公告)日：2016-07-12
申请号：US14238616
申请日：2012-08-03
申请人： Keietsu Abe , Kazuyoshi Kawakami , Tadafumi Ajiri , Manabu Fukumoto , Seiichi Takami , Takanari Togashi , Kimihide Muragaki , Toru Takahashi
发明人： Keietsu Abe , Kazuyoshi Kawakami , Tadafumi Ajiri , Manabu Fukumoto , Seiichi Takami , Takanari Togashi , Kimihide Muragaki , Toru Takahashi
IPC分类号： A61K38/16 , A61K9/16 , C01G49/08 , C09C1/24 , A61K49/18 , B82Y5/00 , B82Y40/00 , B22F1/00 , B82Y30/00
CPC分类号： A61K9/1676 , A61K38/168 , A61K49/1863 , B22F1/0018 , B22F1/0062 , B82Y5/00 , B82Y30/00 , B82Y40/00 , C01G49/08 , C01P2004/62 , C01P2006/12 , C09C1/24
摘要： It has been found that modification of surfaces of nanoparticles with a RolA protein decreases an immunostimulation activity of the nanoparticles on myeloid dendritic cells and also decreases phagocytosis of the nanoparticles by macrophages. The present invention provides nanoparticles being modified with a biological molecule and having an immune-response evasion function.
摘要翻译： 已经发现用RolA蛋白修饰纳米颗粒的表面降低了纳米颗粒在骨髓树突状细胞上的免疫刺激活性，并且还降低了巨噬细胞对纳米颗粒的吞噬作用。 本发明提供了用生物分子修饰并具有免疫应答逃避功能的纳米颗粒。
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3.发明申请Manganese dioxide, method and apparatus for producing the same, and battery active material and battery prepared by using the same 审中-公开二氧化锰，其制造方法和装置，以及使用该二氧化锰制备的电池活性物质和电池公开(公告)号：US20070020171A1
公开(公告)日：2007-01-25
申请号：US11491973
申请日：2006-07-25
申请人： Shinichi Waki , Nobuharu Koshiba , Tadafumi Ajiri
发明人： Shinichi Waki , Nobuharu Koshiba , Tadafumi Ajiri
CPC分类号： H01M4/50 , B01J3/008 , B01J19/2415 , B01J2219/00058 , B01J2219/00135 , C01G45/02 , C01P2002/72 , C01P2004/03 , C01P2004/61 , C01P2004/62 , H01M4/02 , H01M4/502 , H01M2004/021 , Y02P20/544
摘要： Manganese dioxide of this invention comprises monocrystalline particles with a β-type crystal structure. The use of such manganese dioxide as an active material of a battery makes it possible to improve the discharge characteristics and long-term reliability of the battery.
摘要翻译： 本发明的二氧化锰包括具有β型晶体结构的单晶颗粒。 使用这种二氧化锰作为电池的活性物质可以提高电池的放电特性和长期的可靠性。
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公开(公告)号：US08257679B2
公开(公告)日：2012-09-04
申请号：US12510175
申请日：2009-07-27
申请人： Tadafumi Ajiri
发明人： Tadafumi Ajiri
IPC分类号： C01B13/14 , C01G3/02 , C01G25/02 , C01G23/047 , C01G28/00 , C01G17/02 , C01G19/02 , C01G21/02 , C01G9/02 , C01G49/02 , C01G11/02 , C01G13/02 , C01G51/04 , C01G53/04
CPC分类号： C09C1/3669 , B01J3/006 , B01J3/008 , B82Y30/00 , C01B13/145 , C01P2002/82 , C01P2004/04 , C01P2004/64 , C09C1/043 , C09C1/24 , C09C1/3063 , C09C1/407 , C09C3/08 , Y10T428/2982
摘要： A technique for bonding an organic group with the surface of fine particles such as nanoparticles through strong linkage is provided, whereas such fine particles are attracting attention as materials essential for development of high-tech products because of various unique excellent characteristics and functions thereof. Organically modified metal oxide fine particles can be obtained by adapting high-temperature, high-pressure water as a reaction field to bond an organic matter with the surface of metal oxide fine particles through strong linkage. The use of the same condition enables not only the formation of metal oxide fine particles but also the organic modification of the formed fine particles. The resulting organically modified metal oxide fine particles exhibit excellent properties, characteristics and functions.
摘要翻译： 提供了通过强连接将有机基团与微粒如纳米颗粒的表面结合的技术，而由于各种独特的优异特性和功能，这种细颗粒作为高科技产品开发所必需的材料引起了注意。 通过适应高温高压水作为反应场，通过强连接将有机物与金属氧化物细颗粒的表面结合，可以获得有机改性的金属氧化物微粒。 使用相同的条件不仅可以形成金属氧化物细颗粒，而且可以使形成的细颗粒的有机改性。 得到的有机改性金属氧化物微粒表现出优异的性能，特性和功能。
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5.发明申请ORGANIC-INORGANIC COMPOSITE PARTICLES, PARTICLE DISPERSION, PARTICLE-DISPERSED RESIN COMPOSITION, AND METHOD FOR PRODUCING ORGANIC-INORGANIC COMPOSITE PARTICLES 审中-公开有机无机复合颗粒，颗粒分散体，颗粒分散树脂组合物和生产有机无机复合颗粒的方法公开(公告)号：US20110247523A1
公开(公告)日：2011-10-13
申请号：US13084843
申请日：2011-04-12
申请人： Yoshiharu HATAKEYAMA , Junichi Nagase , Shusaku Shibata , Saori Fukuzaki , Tatsuki Nagatsuka , Takahiro Fukuoka , Tadafumi Ajiri
发明人： Yoshiharu HATAKEYAMA , Junichi Nagase , Shusaku Shibata , Saori Fukuzaki , Tatsuki Nagatsuka , Takahiro Fukuoka , Tadafumi Ajiri
CPC分类号： C07F5/003 , C07F9/3808 , C07F9/4006
摘要： The organic-inorganic composite particles can be dispersed as primary particles in a solvent and/or a resin and have a plurality of mutually different organic groups on the surface of inorganic particles.
摘要翻译： 有机 - 无机复合粒子可以作为一次粒子分散在溶剂和/或树脂中，并且在无机粒子的表面上具有多个相互不同的有机基团。
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公开(公告)号：US06921820B2
公开(公告)日：2005-07-26
申请号：US10247623
申请日：2002-09-20
申请人： Kunio Arai , Tadafumi Ajiri , Hideo Hattori , Mitsuru Sasaki
发明人： Kunio Arai , Tadafumi Ajiri , Hideo Hattori , Mitsuru Sasaki
CPC分类号： C08B15/08 , Y02P20/544 , Y10T428/249921
摘要： A method for forming II-type cellulose, which comprises introducing together a slurry having water and a I-type cellulose dispersed therein and water in the state of high temperature and high pressure to a tubular reactor (28) contacting the I-type cellulose with a hot water in a supercritical state or subcritical state for a predetermined time in the tubular reactor (28), to thereby cleave a part of the hydrogen bonds in the I-type cellulose and dissolve the I-type cellulose into the water in a supercritical state or subcritical state, cooling a cellulose solution discharged from the tubular reactor (28) in a cooler (30) to room temperature or lower, followed by allowing to stand, to thereby precipitate crystals of II-type cellulose having a molecular weight lower than that of the I-type cellulose, and separating the resultant II-type cellulose from a solvent. The method allows the preparation of pure II-type cellulose by the use of a simple process.
摘要翻译： 一种形成II型纤维素的方法，其包括将具有水分和I型纤维素分散在其中的高温高压状态的水引入与I型纤维素接触的管状反应器（28）和 在管状反应器（28）中处于超临界状态或亚临界状态的预定时间的热水，从而切割I型纤维素中的一部分氢键，并将I型纤维素溶解在超临界水中 状态或亚临界状态，将冷却器（30）中从管式反应器（28）排出的纤维素溶液冷却至室温以下，然后静置，使析出的分子量低于 I型纤维素，并将所得II型纤维素与溶剂分离。 该方法允许通过简单的方法制备纯的II型纤维素。
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公开(公告)号：US20120308823A1
公开(公告)日：2012-12-06
申请号：US13535103
申请日：2012-06-27
申请人： Tadafumi Ajiri
发明人： Tadafumi Ajiri
IPC分类号： C07F15/06 , C07F7/18 , C07F7/10 , C07F5/06 , C07F3/06 , C07F5/00 , C07F15/02 , C07F15/04 , C07F7/28 , C07F13/00 , B82Y40/00 , B82Y30/00
摘要： A technique for bonding an organic group with the surface of fine particles such as nanoparticles through strong linkage is provided, whereas such fine particles are attracting attention as materials essential for development of high-tech products because of various unique excellent characteristics and functions thereof. Organically modified metal oxide fine particles can be obtained by adapting high-temperature, high-pressure water as a reaction field to bond an organic matter with the surface of metal oxide fine particles through strong linkage. The use of the same condition enables not only the formation of metal oxide fine particles but also the organic modification of the formed fine particles. The resulting organically modified metal oxide fine particles exhibit excellent properties, characteristics and functions.
摘要翻译： 提供了通过强连接将有机基团与微粒如纳米颗粒的表面结合的技术，而由于各种独特的优异特性和功能，这种细颗粒作为高科技产品开发所必需的材料引起了注意。 通过适应高温高压水作为反应场，通过强连接将有机物与金属氧化物细颗粒的表面结合，可以获得有机改性的金属氧化物微粒。 使用相同的条件不仅可以形成金属氧化物细颗粒，而且可以使形成的细颗粒的有机改性。 得到的有机改性金属氧化物微粒表现出优异的性能，特性和功能。
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公开(公告)号：US20100092663A1
公开(公告)日：2010-04-15
申请号：US12510175
申请日：2009-07-27
申请人： Tadafumi Ajiri
发明人： Tadafumi Ajiri
CPC分类号： C09C1/3669 , B01J3/006 , B01J3/008 , B82Y30/00 , C01B13/145 , C01P2002/82 , C01P2004/04 , C01P2004/64 , C09C1/043 , C09C1/24 , C09C1/3063 , C09C1/407 , C09C3/08 , Y10T428/2982
摘要： A technique for bonding an organic group with the surface of fine particles such as nanoparticles through strong linkage is provided, whereas such fine particles are attracting attention as materials essential for development of high-tech products because of various unique excellent characteristics and functions thereof. Organically modified metal oxide fine particles can be obtained by adapting high-temperature, high-pressure water as a reaction field to bond an organic matter with the surface of metal oxide fine particles through strong linkage. The use of the same condition enables not only the formation of metal oxide fine particles but also the organic modification of the formed fine particles. The resulting organically modified metal oxide fine particles exhibit excellent properties, characteristics and functions.
摘要翻译： 提供了通过强连接将有机基团与微粒如纳米颗粒的表面结合的技术，而由于各种独特的优异特性和功能，这种细颗粒作为高科技产品开发所必需的材料引起了注意。 通过适应高温高压水作为反应场，通过强连接将有机物与金属氧化物细颗粒的表面结合，可以获得有机改性的金属氧化物微粒。 使用相同的条件不仅可以形成金属氧化物细颗粒，而且可以使形成的细颗粒的有机改性。 得到的有机改性金属氧化物微粒表现出优异的性能，特性和功能。
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公开(公告)号：US5433878A
公开(公告)日：1995-07-18
申请号：US229687
申请日：1994-04-19
申请人： Kunio Arai , Tadafumi Ajiri , Shin-ichi Yuki , Isao Ota
发明人： Kunio Arai , Tadafumi Ajiri , Shin-ichi Yuki , Isao Ota
IPC分类号： B01J3/00 , C01G49/00 , C04B35/626 , H01F1/11 , C04B35/26
CPC分类号： C04B35/626 , B01J3/008 , C01G49/0036 , C01P2004/04 , C01P2004/22 , C01P2004/62
摘要： A method for producing fine particles of barium ferrite, which comprises reacting an aqueous solution comprising an iron compound, a barium compound and an alkaline substance, wherein the molar ratio of hydroxyl groups of the alkaline substance to the total of anions of the iron compound and the barium compound in the aqueous solution is from 1 to 4, and the reaction is carried out at a temperature of at least 250.degree. C. under a pressure of at least 200 kg/cm.sup.2 using a flow type reactor.
摘要翻译： 一种钡铁氧体微粒的制造方法，其特征在于，使含有铁化合物，钡化合物和碱性物质的水溶液与碱性物质的羟基与铁化合物的阴离子的总量的摩尔比和 水溶液中的钡化合物为1至4，并且使用流式反应器在至少200kg / cm 2的压力下在至少250℃的温度下进行反应。
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公开(公告)号：US07803347B2
公开(公告)日：2010-09-28
申请号：US11173348
申请日：2005-07-01
申请人： Tadafumi Ajiri
发明人： Tadafumi Ajiri
CPC分类号： C09C1/3669 , B01J3/006 , B01J3/008 , B82Y30/00 , C01B13/145 , C01P2002/82 , C01P2004/04 , C01P2004/64 , C09C1/043 , C09C1/24 , C09C1/3063 , C09C1/407 , C09C3/08 , Y10T428/2982
摘要： A technique for bonding an organic group with the surface of fine particles such as nanoparticles through strong linkage is provided, whereas such fine particles are attracting attention as materials essential for development of high-tech products because of various unique excellent characteristics and functions thereof. Organically modified metal oxide fine particles can be obtained by adapting high-temperature, high-pressure water as a reaction field to bond an organic matter with the surface of metal oxide fine particles through strong linkage. The use of the same condition enables not only the formation of metal oxide fine particles but also the organic modification of the formed fine particles. The resulting organically modified metal oxide fine particles exhibit excellent properties, characteristics and functions.
摘要翻译： 提供了通过强连接将有机基团与微粒如纳米颗粒的表面结合的技术，而由于各种独特的优异特性和功能，这种细颗粒作为高科技产品开发所必需的材料引起了注意。 通过适应高温高压水作为反应场，通过强连接将有机物与金属氧化物细颗粒的表面结合，可以获得有机改性的金属氧化物微粒。 使用相同的条件不仅可以形成金属氧化物细颗粒，而且可以使形成的细颗粒的有机改性。 得到的有机改性金属氧化物微粒表现出优异的性能，特性和功能。
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