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公开(公告)号：US20080208197A1
公开(公告)日：2008-08-28
申请号：US11998473
申请日：2007-11-30
申请人： Kelly Ammann , Vincent P. Novak , Robert Schneider
发明人： Kelly Ammann , Vincent P. Novak , Robert Schneider
IPC分类号： A61F5/00
CPC分类号： A61B17/15 , A61B17/152 , A61B17/1615 , A61B17/1675 , A61B17/1732 , A61B17/1764 , A61B2017/00004 , A61B2017/1602 , A61B2090/034
摘要： A method for performing an open wedge, high tibial osteotomy, the method comprising: identifying a cutting plane through the tibia and a boundary line for terminating a cut made along the cutting plane, wherein the boundary line is located within the tibia, parallel to the anterior-posterior slope of the tibia and parallel to the sagittal plane of the patient; positioning a hollow cylinder adjacent to an exterior surface of the tibia and co-axial with the boundary line; positioning a fluoroscope so that its field of view is parallel to the anterior-posterior slope of the tibia, parallel to the sagittal plane of the patient, and co-axial with the hollow cylinder; imaging with the fluoroscope and observing the profile of the hollow cylinder so as to confirm that the hollow cylinder is aligned co-axial with the boundary line; advancing an apex pin through the hollow cylinder and into the tibia along the boundary line so as to provide a positive stop at the boundary line for limiting cutting along the cutting plane; cutting the tibia along the cutting plane, with the cut terminating at the boundary line; moving the tibia on either side of the cut apart so as to form a wedge-like opening in the tibia; and stabilizing the tibia. A method for performing an open wedge, high tibial osteotomy, the method comprising: identifying a cutting plane through the tibia and a boundary line for terminating a cut made along the cutting plane, wherein the boundary line is located within the tibia, parallel to the anterior-posterior slope of the tibia and parallel to the sagittal plane of the patient; positioning a hollow apex pin adjacent to an exterior surface of the tibia and co-axial with the boundary line; positioning a fluoroscope so that its field of view is parallel to the anterior-posterior slope of the tibia, parallel to the sagittal plane of the patient, and co-axial with the hollow apex pin; imaging with the fluoroscope and observing the profile of the hollow apex pin so as to confirm that the hollow apex pin is aligned co-axial with the boundary line; advancing the hollow apex pin into the tibia along the boundary line so as to provide a positive stop at the boundary line for limiting cutting along the cutting plane; cutting the tibia along the cutting plane, with the cut terminating at the boundary line; moving the tibia on either side of the cut apart so as to form a wedge-like opening in the tibia; and stabilizing the tibia.
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2.发明授权公开(公告)号：US08888785B2
公开(公告)日：2014-11-18
申请号：US11396490
申请日：2006-04-03
CPC分类号： A61B17/1764 , A61B17/15 , A61B17/152 , A61B17/1675 , A61B17/1732 , A61B17/68 , A61B17/8095 , A61B90/03 , A61B2017/1602
摘要： An apparatus and method for performing an open wedge osteotomy. The apparatus includes devices for forming an open wedge osteotomy in bone, including a keyed-wedge implant. The method includes the steps of forming a cut in a bone, forming a keyhole in the bone surface at the proximal end of the cut, and positioning a keyed wedge-shaped implant into the cut formed into the bone.
摘要翻译： 用于执行开放性楔形截骨术的装置和方法。 该装置包括用于在骨中形成开放楔形截骨术的装置，包括楔形楔植入物。 该方法包括以下步骤：在骨头中形成切口，在切口的近端处在骨表面中形成锁孔，并将楔形楔形植入物定位到形成骨中的切口中。
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3.发明申请公开(公告)号：US20090287217A1
公开(公告)日：2009-11-19
申请号：US12387546
申请日：2009-05-04
IPC分类号： A61B17/58
CPC分类号： A61B17/1764 , A61B17/15 , A61B17/152 , A61B17/1675 , A61B17/1732 , A61B17/68 , A61B17/8095 , A61B90/03 , A61B2017/1602
摘要： Apparatus for performing an open wedge, high tibial osteotomy, the apparatus comprising: cutting apparatus for forming an osteotomy cut in the tibia, the cutting apparatus comprising: targeting apparatus for identifying a cutting plane through the tibia and a boundary line for terminating a cut made along the cutting plane, wherein the boundary line is located within the tibia, parallel to the anterior-posterior slope of the tibia and parallel to the sagittal plane of the patient. A method for performing an open wedge, high tibial osteotomy, the method comprising: positioning targeting apparatus for identifying a cutting plane through the tibia and a boundary line for terminating a cut made along the cutting plane, wherein the boundary line is located within the tibia, parallel to the anterior-posterior slope of the tibia and parallel to the sagittal plane of the patient; cutting the bone along the cutting plane, with the cut terminating at the boundary line; moving the bone on either-side of the cut apart so as to form the wedge-like opening in the bone; and stabilizing the bone.
摘要翻译： 用于执行开放式楔形物，高胫骨截骨术的装置，所述装置包括：用于在胫骨中切割截骨的切割装置，所述切割装置包括：用于识别穿过胫骨的切割平面的靶向装置和用于终止切割的边界线 沿着切割平面，其中边界线位于胫骨内，平行于胫骨的前 - 后斜面并且平行于患者的矢状平面。 一种用于执行开放楔形，高胫骨截骨术的方法，所述方法包括：定位用于通过胫骨识别切割平面的定位装置和用于终止沿切割平面制成的切口的边界线，其中边界线位于胫骨内 平行于胫骨前后斜面并平行于患者的矢状面; 沿着切割平面切割骨头，切口终止于边界线; 在切割的两侧移动骨头，以在骨中形成楔形开口; 并稳定骨骼。
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4.发明授权公开(公告)号：US08702715B2
公开(公告)日：2014-04-22
申请号：US12387546
申请日：2009-05-04
IPC分类号： A61B17/58
CPC分类号： A61B17/1764 , A61B17/15 , A61B17/152 , A61B17/1675 , A61B17/1732 , A61B17/68 , A61B17/8095 , A61B90/03 , A61B2017/1602
摘要： Apparatus for performing an open wedge, high tibial osteotomy, the apparatus comprising: cutting apparatus for forming an osteotomy cut in the tibia, the cutting apparatus comprising: targeting apparatus for identifying a cutting plane through the tibia and a boundary line for terminating a cut made along the cutting plane, wherein the boundary line is located within the tibia, parallel to the anterior-posterior slope of the tibia and parallel to the sagittal plane of the patient. A method for performing an open wedge, high tibial osteotomy, the method comprising: positioning targeting apparatus for identifying a cutting plane through the tibia and a boundary line for terminating a cut made along the cutting plane, wherein the boundary line is located within the tibia, parallel to the anterior-posterior slope of the tibia and parallel to the sagittal plane of the patient; cutting the bone along the cutting plane, with the cut terminating at the boundary line; moving the bone on either side of the cut apart so as to form the wedge-like opening in the bone; and stabilizing the bone.
摘要翻译： 用于执行开放式楔形物，高胫骨截骨术的装置，所述装置包括：用于在胫骨中切割截骨的切割装置，所述切割装置包括：用于识别穿过胫骨的切割平面的靶向装置和用于终止切割的边界线 沿着切割平面，其中边界线位于胫骨内，平行于胫骨的前 - 后斜面并且平行于患者的矢状平面。 一种用于执行开放楔形，高胫骨截骨术的方法，所述方法包括：定位用于通过胫骨识别切割平面的定位装置和用于终止沿切割平面制成的切口的边界线，其中边界线位于胫骨内 平行于胫骨前后斜面并平行于患者的矢状面; 沿着切割平面切割骨头，切口终止于边界线; 在分开的两侧移动骨头，以在骨中形成楔形开口; 并稳定骨骼。
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5.发明授权公开(公告)号：US08409209B2
公开(公告)日：2013-04-02
申请号：US11986444
申请日：2007-11-21
申请人： Kelly Ammann , Vincent P. Novak , Robert Schneider
发明人： Kelly Ammann , Vincent P. Novak , Robert Schneider
IPC分类号： A61F2/28
CPC分类号： A61F2/389 , A61B17/15 , A61B17/152 , A61B17/1615 , A61B17/1675 , A61B17/1732 , A61B17/1764 , A61B17/68 , A61B17/8095 , A61B2017/00004 , A61B2017/1602 , A61B2090/034 , A61F2002/30535 , A61F2250/0058
摘要： An osteotomy implant for disposition in a wedge-shaped osteotomy opening in a bone, the implant comprising a body for disposition within the wedge-shaped osteotomy opening in the bone and supporting the bone while healing occurs; at least one key formed integral with the body for stabilizing the body relative to the adjacent bone while healing occurs; and at least one fenestration extending through the body for permitting bone growth through the implant.
摘要翻译： 一种截骨植入物，用于配置在骨头中的楔形截骨开口中，所述植入物包括用于在骨头内的楔形截骨开口内部配置并在愈合时支撑骨骼的主体; 与身体一体形成的至少一个键，用于在发生愈合时相对于相邻骨稳定身体; 以及延伸穿过本体以允许骨通过植入物生长的至少一个开窗。
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6.发明申请公开(公告)号：US20080208199A1
公开(公告)日：2008-08-28
申请号：US11986444
申请日：2007-11-21
申请人： Kelly Ammann , Vincent P. Novak , Robert Schneider
发明人： Kelly Ammann , Vincent P. Novak , Robert Schneider
CPC分类号： A61F2/389 , A61B17/15 , A61B17/152 , A61B17/1615 , A61B17/1675 , A61B17/1732 , A61B17/1764 , A61B17/68 , A61B17/8095 , A61B2017/00004 , A61B2017/1602 , A61B2090/034 , A61F2002/30535 , A61F2250/0058
摘要： An osteotomy implant for disposition in a wedge-shaped osteotomy opening in a bone, the implant comprising: a body for disposition within the wedge-shaped osteotomy opening in the bone and supporting the bone while healing occurs; at least one key formed integral with the body for stabilizing the body relative to the adjacent bone while healing occurs; and at least one fenestration extending through the body for permitting bone growth through the implant. An osteotomy implant for disposition in a wedge-shaped osteotomy opening in a bone, the implant comprising: a body for disposition within the wedge-shaped osteotomy opening in the bone and supporting the bone while healing occurs; and at least one key formed integral with the body for stabilizing the body relative to the adjacent bone while healing occurs; wherein at least a portion of the body and the at least one key are formed out of a relatively strong, load-bearing material whereby to stabilize the bone during healing; and further wherein at least a portion of the body is formed out of a bone growth-promoting material whereby to enhance bone healing across the osteotomy opening in the bone.
摘要翻译： 一种截骨植入物，用于配置在骨中的楔形截骨开口中，所述植入物包括：用于在骨头内的楔形截骨开口内部配置并在愈合时支撑骨骼的主体; 与身体一体形成的至少一个键，用于在发生愈合时相对于相邻骨稳定身体; 以及延伸穿过本体以允许骨通过植入物生长的至少一个开窗。 一种截骨植入物，用于配置在骨中的楔形截骨开口中，所述植入物包括：用于在骨头内的楔形截骨开口内部配置并在愈合时支撑骨骼的主体; 以及与身体一体形成的至少一个键，用于在发生愈合时相对于相邻骨稳定身体; 其中所述主体和所述至少一个键的至少一部分由相对较强的承载材料形成，从而在愈合过程中稳定骨骼; 并且其中所述主体的至少一部分由骨生长促进材料形成，从而通过骨中截骨开口增强骨愈合。
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公开(公告)号：US08211112B2
公开(公告)日：2012-07-03
申请号：US11352103
申请日：2006-02-09
申请人： Vincent P. Novak , Kelly Ammann
发明人： Vincent P. Novak , Kelly Ammann
IPC分类号： A61F5/00
CPC分类号： A61B17/8095 , A61F2002/30736
摘要： An osteotomy implant for supporting an open wedge osteotomy and method of use are described. In one form, the implant is configured to contain a graft material within the osteotomy. In another form, the implant is composed of multiple parts capable of being assembled either before or after insertion into the osteotomy.
摘要翻译： 描述了用于支撑开放楔形截骨术的截骨植入物和使用方法。 在一种形式中，植入物构造成在截骨术内容纳移植材料。 在另一种形式中，植入物由能够在插入截骨术之前或之后组装的多个部件组成。
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8.发明授权Method and apparatus for forming a wedge-like opening in a bone for an open wedge osteotomy 有权用于在开放式楔形截骨术中在骨中形成楔形开口的方法和装置公开(公告)号：US08496662B2
公开(公告)日：2013-07-30
申请号：US11350333
申请日：2006-02-08
申请人： Vincent P. Novak , Kelly Ammann , Dennis McDevitt
发明人： Vincent P. Novak , Kelly Ammann , Dennis McDevitt
IPC分类号： A61B17/56
CPC分类号： A61B17/152 , A61B17/15 , A61B17/1732 , A61B17/1764 , A61B17/8095
摘要： The present application provides an apparatus for forming and method of creating a wedge-like opening in a bone for an open wedge osteotomy by identifying a cutting plane through the bone; and inserting an apex pin along the cutting plane to limit cutting and minimize stress risers in the bone.
摘要翻译： 本申请提供了一种用于形成的装置和通过识别穿过骨头的切割平面在开口楔形截骨术中在骨头中形成楔形开口的方法; 并且沿着切割平面插入顶销以限制切割并使骨中的应力提升最小化。
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9.发明申请Automated process for isolating and amplifying a target nucleic acid sequence using a robotic pipettor 无效使用机器人移液器分离和扩增靶核酸序列的自动化方法公开(公告)号：US20050239127A1
公开(公告)日：2005-10-27
申请号：US11169112
申请日：2005-06-29
申请人： Kelly Ammann , Ralph Burns , Ernest Hansberry , Glenn Horner , Cheryl Jakub , John Kling , Donald Nieglos , Robert Schneider , Robert Smith
发明人： Kelly Ammann , Ralph Burns , Ernest Hansberry , Glenn Horner , Cheryl Jakub , John Kling , Donald Nieglos , Robert Schneider , Robert Smith
IPC分类号： B01L99/00 , B01F9/00 , B01F15/00 , B01L7/00 , C12M1/00 , C12M1/34 , C12M1/36 , C12P19/34 , C12Q1/68 , G01N35/00 , G01N35/02 , G01N35/04 , G01N35/10
CPC分类号： C12Q1/6834 , B01F9/0001 , B01F9/0014 , B01F9/0021 , B01F2009/0074 , B01L7/52 , B01L7/5255 , B01L9/06 , B01L2200/147 , B01L2300/1822 , B01L2300/1827 , B03C1/282 , B03C1/288 , B03C1/30 , B03C2201/26 , C12Q1/6813 , C12Q1/6832 , C12Q2537/10 , G01N35/0098 , G01N35/0099 , G01N35/025 , G01N35/1065 , G01N2035/00356 , G01N2035/00524 , G01N2035/0437 , G01N2035/0455 , G01N2035/103 , Y10T29/53657 , Y10T29/53683 , Y10T29/53843 , Y10T156/1105 , Y10T156/1906 , Y10T436/11 , Y10T436/111666 , Y10T436/113332 , Y10T436/114998 , Y10T436/119163 , Y10T436/2575
摘要： An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample, incubating the sample at prescribed temperatures for prescribed periods, preforming an analyte isolation procedure, and ascertaining the presence of a target analyte. An automated receptacle transporting system moves the reaction receptacles from one station to the next. The analyzer further includes devices for carrying a plurality of specimen tubes and disposable pipette tips in a machine-accessible manner, a device for agitating containers of target capture reagents comprising suspensions of solid support material and for presenting the containers for machine access thereto, and a device for holding containers of reagents in a temperature controlled environment and presenting the containers for machine access thereto. A method for performing an automated diagnostic assay includes an automated process for isolating and amplifying a target analyte. The process is performed by automatically moving each of a plurality of reaction receptacles containing a solid support material and a fluid sample between stations for incubating the contents of the reaction receptacle and for separating the target analyte bound to the solid support from the fluid sample. An amplification reagent is added to the separated analyte after the analyte separation step and before a final incubation step.
摘要翻译： 用于执行多个诊断测定的自动分析仪同时包括多个站或模块，其中对反应容器中包含的流体样品进行分析方面的分析。 分析仪包括用于自动准备标本样品，在规定温度下规定时间孵育样品，预处理分析物分离程序以及确定目标分析物的存在的站。 自动插座输送系统将反应容器从一个站移动到另一个站。 分析仪还包括用于以机器可接近的方式携带多个样本管和一次性移液管尖端的装置，用于搅拌包含固体支持材料的悬浮液并用于提供用于机器通入的容器的靶捕获试剂的容器的装置，以及 用于在温度受控的环境中容纳试剂容器的装置，并且提供用于机器通入的容器。 执行自动诊断测定的方法包括用于分离和扩增靶分析物的自动化方法。 该过程通过在站之间自动移动包含固体支持材料和流体样品的多个反应容器中的每一个来实现，用于孵化反应容器的内容物并将与固体支持物结合的目标分析物与流体样品分离。 在分析物分离步骤之后和最终孵育步骤之前，将分离的分析物加入扩增试剂。
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10.发明申请公开(公告)号：US20070244487A1
公开(公告)日：2007-10-18
申请号：US11607321
申请日：2006-12-01
申请人： Kelly Ammann , Vincent Novak , Robert Schneider , Ralph Burns
发明人： Kelly Ammann , Vincent Novak , Robert Schneider , Ralph Burns
IPC分类号： A61B17/58
CPC分类号： A61B17/1675 , A61B17/15 , A61B17/152 , A61B17/1615 , A61B17/1732 , A61B17/1764 , A61B17/68 , A61B17/8095 , A61B2017/1602 , A61B2090/034 , A61F2002/30736
摘要： Apparatus for performing an open wedge, high tibial osteotomy, the apparatus comprising: a wedge-shaped implant for disposition in a wedge-shaped opening created in the tibia, wherein the wedge-shaped implant comprises at least two keys, laterally offset from one another, for disposition in corresponding keyholes formed in the tibia adjacent to the wedge-shaped opening created in the tibia. Apparatus for performing an open wedge, high tibial osteotomy, the apparatus comprising: a wedge-shaped implant for disposition in a wedge-shaped opening created in the tibia, wherein the wedge-shaped implant comprises at least two keys, vertically offset from one another, for disposition in corresponding keyholes formed in the tibia adjacent to the wedge-shaped opening created in the tibia, and a shear rib, laterally offset from the at least two keys, for disposition in a corresponding shear rib keyhole formed in the tibia adjacent to the wedge-shaped opening created in the tibia.
摘要翻译： 用于执行开放楔形，高胫骨截骨术的装置，所述装置包括：楔形植入物，用于设置在胫骨中形成的楔形开口，其中所述楔形植入物包括至少两个彼此横向偏移的键 ，用于配置在与在胫骨中形成的楔形开口相邻的胫骨中形成的相应的键槽中。 用于执行开放楔形物，高胫骨截骨术的装置，所述装置包括：楔形植入物，用于设置在胫骨中形成的楔形开口，其中所述楔形植入物包括彼此垂直偏移的至少两个键 用于配置在与在胫骨中形成的楔形开口相邻的胫骨中形成的相应的钥匙孔中，以及剪切肋，所述剪切肋从所述至少两个键横向偏移，用于配置在相邻的胫骨中形成的对应的剪切肋锁孔中 在胫骨处形成的楔形开口。
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