Clear aqueous ceramide composition
    1.
    发明授权
    Clear aqueous ceramide composition 有权
    透明水性神经酰胺组合物

    公开(公告)号:US08313755B2

    公开(公告)日:2012-11-20

    申请号:US09848225

    申请日:2001-05-04

    IPC分类号: A61K8/02 A01N37/12

    摘要: Provided is a clear aqueous ceramide composition comprising 1.0 to 5.0% by weight, based on the total composition, of a ceramide represented by formula (I): wherein R1 represents a hydrocarbon group having 9 to 17 carbon atoms; and R2 represents an acyl group having 2 to 30 carbon atoms which can contain a hydroxyl group, a long-chain fatty acid having 12 to 24 carbon atoms, a nonionic surface active agent, and water. The clear aqueous composition is useful as cosmetics, bath agents, hair-care products, external preparations for the skin, skin protective preparations, particularly medical external preparations for the treatment or protection of the skin, or a component making up these preparations.

    摘要翻译: 本发明提供一种透明含水神经酰胺组合物,其包含基于总组合物1.0至5.0重量%的由式(I)表示的神经酰胺:其中R 1表示具有9至17个碳原子的烃基; R2表示可含有羟基的碳原子数2〜30的酰基,碳原子数12〜24的长链脂肪酸,非离子表面活性剂,水。 透明水性组合物可用作化妆品,浴剂,护发产品,皮肤外用剂,皮肤保护制剂,特别是用于治疗或保护皮肤的医用外用制剂,或构成这些制剂的组分。

    Lipid composition containing a liquid crystal structure

    公开(公告)号:US06528074B2

    公开(公告)日:2003-03-04

    申请号:US09874312

    申请日:2001-06-06

    IPC分类号: A61K700

    摘要: This invention relates to a novel lipid composition for use in cosmetics capable of increasing moisture-keeping ability or barrier function of the stratum corneum, protecting the skin and improving dry or rough skin, and to products which use the same, such as cosmetics and medicaments. Particularly, it relates to a lipid composition which comprises at least one component (A) selected from the group consisting of a 2-acylaminoalkane-1,3-diol and optically active compounds thereof, at least one component (B) selected from the group consisting of a 2-acylaminoalkane-1,3-diol in which at least one of the &agr;-position and &bgr;-position of the acyl group is substituted with hydroxyl group and optically active compounds thereof and at least one component (C) selected from sterols, wherein the components (A), (B) and (C) are mixed at a ratio that constructs a liquid crystal structure, and to products which contain the lipid composition, such as cosmetics and medicaments.

    Method and agent for enhancing diffusivity and long-lasting property of fragrance

    公开(公告)号:US07538081B2

    公开(公告)日:2009-05-26

    申请号:US09949718

    申请日:2001-09-12

    IPC分类号: A61K8/00

    摘要: A fragrance composition having an excellent diffusivity and long-lasting property of fragrance and a cosmetic, toiletry, bath composition, food and drink and pharmaceutical having an excellent diffusivity and long-lasting property of fragrance by using a novel fixative. A compound represented by the following general formula (1) is incorporated in a fragrance composition or the foregoing products. The amount of the compound of the general formula (1) to be incorporated in the fragrance composition is preferably from 0.01 to 90% by weight. The amount of the compound of the general formula (1) to be incorporated directly in the foregoing products is preferably from 0.0001 to 2.0 times (by weight) the weight of the aroma composition and/or composition to be incorporated therein. In this arrangement, a fragrance composition or products having an enhanced diffusivity and long-lasting property of fragrance can be obtained without causing any safety problem on human being. wherein A represents H or OH group; B represents H or methyl group; and n represents an integer of from 0 to 2.

    Process for producing 2-vinylcyclododecanone
    5.
    发明授权
    Process for producing 2-vinylcyclododecanone 失效
    2-乙烯基环十二酮的制备方法

    公开(公告)号:US06548711B2

    公开(公告)日:2003-04-15

    申请号:US09876231

    申请日:2001-06-08

    IPC分类号: C07C49607

    CPC分类号: C07C45/67 C07C49/647

    摘要: A process for producing 2-vinylcyclododecanone, the process comprising isomerizing 2-ethylidenecyclododecanone represented by the following formula (1): wherein the wavy line signifies that the double bond is a Z-isomer, an E-isomer or a mixture of an E-isomer and a Z-isomer; in the presence of a catalyst and separating 2-vinylcyclododecanone represented by the following formula (2) from the reaction product by fractionation:

    摘要翻译: 一种生产2-乙烯基环十二酮的方法,该方法包括由下式(1)表示的2-亚乙基环十二烷异构化:其中波浪线表示双键是Z-异构体,E-异构体或E- 异构体和Z-异构体; 在催化剂的存在下,通过分馏从反应产物中分离出由下式(2)表示的2-乙烯基环十二烷:

    Process for producing aromatic amines
    6.
    发明授权
    Process for producing aromatic amines 失效
    生产芳香胺的方法

    公开(公告)号:US06365776B1

    公开(公告)日:2002-04-02

    申请号:US09946468

    申请日:2001-09-06

    IPC分类号: C07C21100

    CPC分类号: C07C209/10 C07C211/54

    摘要: The present invention provides an activator in arylamination using a palladium compound as a catalyst, which is superior to conventional phosphines in stability and performance. With the phosphine sulfide as an activator, an arylamination reaction achieves improved selectivity to produce a desired aromatic amine in an obviously increased yield as compared with a reaction using the corresponding phosphine compound. Moreover, the phosphine sulfide of the invention is impervious to oxidation and exists stably in air and therefore sufficiently withstands use on an industrial scale.

    摘要翻译: 本发明提供使用钯化合物作为催化剂的芳基化活化剂,其在稳定性和性能方面优于常规膦。 与使用相应的膦化合物的反应相比,以硫化氢作为活化剂,芳基化反应实现了以明显增加的产率产生所需芳族胺的选择性。 此外,本发明的硫化膦不能氧化,在空气中稳定地存在,因此能够充分地耐受工业规模的使用。