公开(公告)号：US07858937B2

公开(公告)日：2010-12-28

申请号：US12303037

申请日：2006-05-30

申请人： Kiyoshi Ogawa ,  Takeharu Etoh

发明人： Kiyoshi Ogawa ,  Takeharu Etoh

IPC分类号： H01J37/252

CPC分类号： H01J49/0004 ,  H01J49/061

摘要： A sample S is irradiated with a two-dimensionally spread ray of laser light to simultaneously ionize substances within a two-dimensional area on the sample. The resultant ions are mass-separated by a TOF mass separator 4 without changing the interrelationship of the emission points of the ions. The separated ions are then directed to a two-dimensional detector section 7 through a deflection electric field created by deflection electrodes 61 and 62. The two-dimensional detector section 7 consists of a plurality of detection units 7a arranged in parallel, each unit including an MCP 8a, fluorescent plate 9a and two-dimensional array detector 10a. The magnitude of deflecting the flight path of the ions by the deflection electric field is changed in a stepwise manner with the lapse of time from the generation of the ions so that a plurality of mass analysis images are sequentially projected on each detection unit 7. When the mass analysis image shifts from one detection unit to another, the data acquisition operation by the two-dimensional array detector in the previous detection unit is discontinued. As a result, a predetermined number of the latest images are held inside the detector. Thus, the measurement time can be extended to widen the measurable mass-to-charge ratio range, while ensuring a high mass resolution.

摘要翻译： 用二维扩散的激光照射样品S，以同时电离样品二维区域内的物质。 通过TOF质量分离器4将所得离子质量分离，而不改变离子的发射点的相互关系。 分离的离子然后通过由偏转电极61和62产生的偏转电场被引导到二维检测器部分7.二维检测器部分7由多个并联布置的检测单元7a组成，每个单元包括一个 MCP 8a，荧光板9a和二维阵列检测器10a。 通过偏转电场使离子的飞行路径偏转的大小随着离子的产生经过时间而逐步改变，使得多个质量分析图像顺序投影在每个检测单元7上。当 质量分析图像从一个检测单元移动到另一个检测单元，则中止了先前检测单元中的二维阵列检测器的数据获取操作。 结果，预定数量的最新图像被保持在检测器内部。 因此，可以延长测量时间，以扩大可测量的质荷比范围，同时确保高质量分辨率。

公开(公告)号：US20090272890A1

公开(公告)日：2009-11-05

申请号：US12303037

申请日：2006-05-30

申请人： Kiyoshi Ogawa ,  Takeharu Etoh

发明人： Kiyoshi Ogawa ,  Takeharu Etoh

IPC分类号： H01J49/00

CPC分类号： H01J49/0004 ,  H01J49/061

摘要： A sample S is irradiated with a two-dimensionally spread ray of laser light to simultaneously ionize substances within a two-dimensional area on the sample. The resultant ions are mass-separated by a TOF mass separator 4 without changing the interrelationship of the emission points of the ions. The separated ions are then directed to a two-dimensional detector section 7 through a deflection electric field created by deflection electrodes 61 and 62. The two-dimensional detector section 7 consists of a plurality of detection units 7a arranged in parallel, each unit including an MCP 8a, fluorescent plate 9a and two-dimensional array detector 10a. The magnitude of deflecting the flight path of the ions by the deflection electric field is changed in a stepwise manner with the lapse of time from the generation of the ions so that a plurality of mass analysis images are sequentially projected on each detection unit 7. When the mass analysis image shifts from one detection unit to another, the data acquisition operation by the two-dimensional array detector in the previous detection unit is discontinued. As a result, a predetermined number of the latest images are held inside the detector. Thus, the measurement time can be extended to widen the measurable mass-to-charge ratio range, while ensuring a high mass resolution.

摘要翻译： 用二维扩散的激光照射样品S，以同时电离样品二维区域内的物质。 通过TOF质量分离器4将所得离子质量分离，而不改变离子的发射点的相互关系。 分离的离子然后通过由偏转电极61和62产生的偏转电场被引导到二维检测器部分7.二维检测器部分7由多个并联布置的检测单元7a组成，每个单元包括一个 MCP 8a，荧光板9a和二维阵列检测器10a。 通过偏转电场使离子的飞行路径偏转的大小随着离子的产生经过时间而逐步改变，使得多个质量分析图像顺序投影在每个检测单元7上。当 质量分析图像从一个检测单元移动到另一个检测单元，则中止了先前检测单元中的二维阵列检测器的数据获取操作。 结果，预定数量的最新图像被保持在检测器内部。 因此，可以延长测量时间，以扩大可测量的质荷比范围，同时确保高质量分辨率。

公开(公告)号：US10012572B2

公开(公告)日：2018-07-03

申请号：US13458850

申请日：2012-04-27

申请人： Masaaki Matsuura ,  Masaru Ushijima ,  Masatoshi Wakui ,  Mitsutoshi Setou ,  Shigeki Kajihara ,  Kiyoshi Ogawa

发明人： Masaaki Matsuura ,  Masaru Ushijima ,  Masatoshi Wakui ,  Mitsutoshi Setou ,  Shigeki Kajihara ,  Kiyoshi Ogawa

IPC分类号： G01N1/28 ,  G06F15/00 ,  H01J49/00

CPC分类号： G01N1/28 ,  G06F15/00 ,  H01J49/0004 ,  H01J49/0027

摘要： Provided is a technique for using an optical microscope image of an area on a sample to collect area-specific information characterizing each kind of biological tissue from imaging mass analysis data. On an optical image of a two-dimensional target area on a sample, a difference is examined in the kind of tissue or other features and areas are specified, each regarded as the same kind of tissue. When data processing is initiated, peak information is extracted, for each specified area, from mass spectrum data of all the measurement points. A peak method is applied to each area to extract peak information. Then, when a command to compare a set of areas is given, the peak information of those areas is collected. By comparing the peak information of different areas by a machine learning algorithm or similar judging technique, area-specific peak information is obtained, and this information is stored in memory.

公开(公告)号：US08650721B2

公开(公告)日：2014-02-18

申请号：US12676800

申请日：2008-09-11

申请人： Kiyoshi Ogawa ,  Goushu Kataoka ,  Katsuyasu Ono ,  Yuji Sakata ,  Hitoshi Futaki ,  Masanao Yamazaki

发明人： Kiyoshi Ogawa ,  Goushu Kataoka ,  Katsuyasu Ono ,  Yuji Sakata ,  Hitoshi Futaki ,  Masanao Yamazaki

IPC分类号： A44B11/00 ,  B60R22/22

CPC分类号： B60R22/12 ,  B60R22/22 ,  B60R2022/1806 ,  Y10T24/4047 ,  Y10T24/4086 ,  Y10T24/45241 ,  Y10T24/45623 ,  Y10T24/4736 ,  Y10T24/4745 ,  Y10T29/49826

摘要： A buckle device 10 for a seat belt includes: an anchor plate 11 that can be attached to a vehicle body side; a buckle 20 to which a tongue of the seat belt can be detachably attached; and a woven fabric 30 that is passed through hole portions 14, 26 formed respectively in the anchor plate 11 and the buckle 20, the woven fabric 30 being folded back so as to overlap at least triply and being sewn together in the overlapping part. A tip end portion 31a of the woven fabric 30 tucked into the inner side contacts the opposing buckle 20.

摘要翻译： 用于座椅安全带的带扣装置10包括：可附接到车体侧的锚板11; 安全带的舌头可拆卸地安装在其上的带扣20; 以及穿过分别形成在锚固板11和带扣20中的孔部分14,26的织物30，将织物30折叠成至少三重重叠并在重叠部分缝合在一起。 卷入内侧的织物30的前端部31a与相对的扣环20接触。

公开(公告)号：US08286903B2

公开(公告)日：2012-10-16

申请号：US12945478

申请日：2010-11-12

申请人： Kiyoshi Ogawa ,  Masuo Matsuki

发明人： Kiyoshi Ogawa ,  Masuo Matsuki

IPC分类号： B65H75/48

CPC分类号： B60R22/4676 ,  B60R2022/287 ,  B60R2022/289

摘要： A retractor includes a slide nut that is caused to slide toward a tread head while rotating by a mesh between a first male screw groove and a female screw groove when the tread head is locked and a spindle rotates in a direction for unreeling a webbing, and a slider that is caused to slide toward the slide nut by a mesh between the female screw groove and a second male screw groove. A torsional rigidity of a second shaft part of a torsion bar is larger than that of a first shaft part, and a play is eliminated before a gap such that the slide nut and the slider are integrated.

摘要翻译： 牵开器包括滑动螺母，当滑动螺母被锁定并且主轴沿用于松开织带的方向旋转时，滑动螺母在通过第一外螺纹槽和内螺纹槽之间的网转动的同时朝向胎面头滑动，以及 滑动件通过内螺纹槽和第二外螺纹槽之间的网状物向滑动螺母滑动。 扭杆的第二轴部的扭转刚性大于第一轴部的扭转刚性，并且在滑动螺母和滑块一体化的间隙之前消除了间隙。

公开(公告)号：US20120132799A1

公开(公告)日：2012-05-31

申请号：US13260061

申请日：2009-03-31

申请人： Kazuteru Takahashi ,  Kiyoshi Ogawa ,  Mitsutoshi Setou

发明人： Kazuteru Takahashi ,  Kiyoshi Ogawa ,  Mitsutoshi Setou

IPC分类号： H01J49/26

CPC分类号： H01J49/0004 ,  G01N2001/045

摘要： A samples stage (2) on which a sample (4) is placed can reciprocally move along a guide (5) by a driving mechanism. An image taken by an imaging unit (7) when the sample stage (2) is at an observation position (A) is processed by an image processor (34) and is displayed on a window of a display unit (38). When an analysis operator specifies a measurement area by an operation unit (37), a controller (3) moves, through a stage driver (33), the stage (2) to a sample operation position (B) and a matrix is applied to the specified measurement area by an ejector (9). After that, the stage (2) is moved to an analysis position (C) and a laser light is delivered onto the measurement area on the sample (4) to which the matrix was applied, and the ionization by the MALDI method is performed. This eliminates the need to take out the sample from the apparatus to apply the matrix after the measurement point or measurement area is determined based on a microscopic observation of the sample. Accordingly, the efficiency of the measurement can be increased, and since no positional error of the sample occurs, it is possible to perform an imaging mass analysis for a measurement area of interest with high positional accuracy.

摘要翻译： 其上放置有样品（4）的样品台（2）可以通过驱动机构沿引导件（5）往复运动。 当样本台（2）处于观察位置（A）时由成像单元（7）拍摄的图像由图像处理器（34）处理并显示在显示单元（38）的窗口上。 当分析操作者通过操作单元（37）指定测量区域时，控制器（3）通过平台驱动器（33）将平台（2）移动到采样操作位置（B），并将矩阵应用于 由喷射器（9）指定的测量区域。 之后，将阶段（2）移动到分析位置（C），并将激光输送到施加了矩阵的样品（4）的测量区域上，并通过MALDI方法进行电离。 这消除了在基于样品的显微镜观察确定测量点或测量区域之后，从设备中取出样品以施加基质的需要。 因此，可以提高测量效率，并且由于不发生样本的位置误差，因此可以以高位置精度对感兴趣的测量区域进行成像质量分析。

公开(公告)号：US20120043407A1

公开(公告)日：2012-02-23

申请号：US13264870

申请日：2010-03-31

申请人： Kiyoshi Ogawa ,  Katsuyasu Ono ,  Yuichi Hamano

发明人： Kiyoshi Ogawa ,  Katsuyasu Ono ,  Yuichi Hamano

IPC分类号： B60R22/36

CPC分类号： B60R22/4628 ,  B60R2022/287 ,  B60R2022/4642

摘要： A seatbelt retractor having a switching device with a gas generator and a switch housing having a gas generator housing portion for accommodating the gas generator and a gas flow path that communicates with the gas generator housing portion so that gas generated by the gas generator passes through the gas flow path. Further, the gas generator housing portion and the gas flow path are formed in the switch housing in a curved shape, and a die-cut hole extending in a direction of the gas flow path on an opposite side of the gas flow path to the gas generator housing portion is blocked from the gas flow path by the gas generator.

摘要翻译： 一种安全带卷收器，具有具有气体发生器的开关装置和具有用于容纳气体发生器的气体发生器容纳部分和与气体发生器壳体部分连通的气体流路的开关壳体，使得由气体发生器产生的气体通过 气体流路。 此外，气体发生器壳体部分和气体流动通道在开关壳体中形成为弯曲形状，并且在气体流动路径的与气体的气体流动路径相对的一侧上延伸的冲切孔 发电机壳体部分被气体发生器从气体流动路径阻挡。

公开(公告)号：US08058610B2

公开(公告)日：2011-11-15

申请号：US12515674

申请日：2006-12-05

申请人： Takahiro Harada ,  Sadao Takeuchi ,  Kiyoshi Ogawa ,  Mitsutoshi Setou

发明人： Takahiro Harada ,  Sadao Takeuchi ,  Kiyoshi Ogawa ,  Mitsutoshi Setou

IPC分类号： H01J49/04 ,  H01J49/00

CPC分类号： H01J49/164

摘要： A sample plate 3 with a sample 4 placed thereon is initially set on a stage 2, and a visual image of the sample is taken with a CCD camera 14. This image is stored in an image data memory 23. Then, an operator removes the sample plate 3, sprays a matrix for a MALDI process onto the sample 4 and replaces the plate onto the stage 2. After that, when a predetermined operation is made, a clear image of the sample taken before the application of the matrix is shown on a display unit 24. On this image, the operator specifies a point or area for the analysis. The sample 4 may have been displaced due to the removal and replacement of the plate 3. Accordingly, an image analyzer 44 calculates the direction and magnitude of the displacement, for example, by recognizing the position of the markings provided on the sample plate 3. A displacement corrector 42 computes coordinate values in which the displacement is corrected. Thus, even if a displacement occurs, the mass analysis can be accurately performed on the point or area of the actual sample as specified on the clear visual image taken before the application of the matrix.

摘要翻译： 将样品4放置在其上的样品板3初始设置在载物台2上，用CCD照相机14拍摄样品的视觉图像。该图像存储在图像数据存储器23中。然后，操作者将 样品板3将MALDI工艺的矩阵喷射到样品4上，并将该板替换到载物台2上。之后，当进行预定的操作时，在施加矩阵之前拍摄的样品的清晰图像显示在 在该图像上，操作者指定用于分析的点或区域。 样品4可能由于板3的移除和更换而被移动。因此，图像分析器44例如通过识别设置在样品板3上的标记的位置来计算位移的方向和大小。 位移校正器42计算校正位移的坐标值。 因此，即使发生位移，也可以在施加矩阵之前在清晰的视觉图像上指定的实际样品的点或面积上精确地进行质量分析。

公开(公告)号：US20110011969A1

公开(公告)日：2011-01-20

申请号：US12922839

申请日：2009-04-03

申请人： Kiyoshi Ogawa

发明人： Kiyoshi Ogawa

IPC分类号： B60R22/46

CPC分类号： B60R22/4676 ,  B60R22/4633 ,  B60R2022/4642

摘要： A seat belt retractor (10) is provided with: a spindle (12) around which a seat belt (B) is wound; a torsion bar (17) disposed in a cavity (27) of the spindle (12), an axial end portion of the torsion bar (17) being attached to an axial end portion of the spindle (12); a first pretensioner (16) that is attached to the spindle (12) at least during a collision so as to cause the spindle (12) to rotate in a retraction direction using a gas pressure; and a second pretensioner (18) that is attached to another axial end portion of the torsion bar (17) at least during a collision so as to cause the spindle (12) to rotate in the retraction direction via the torsion bar (17) using the gas pressure.

摘要翻译： 安全带卷收器（10）设有：一个主轴（12），一个安全带（B）绕在该主轴上; 设置在所述心轴（12）的空腔（27）中的扭杆（17），所述扭杆（17）的轴向端部附接到所述心轴（12）的轴向端部; 至少在碰撞期间附接到所述主轴（12）的第一预张紧器（16），以便使所述主轴（12）使用气压在回缩方向上旋转; 以及至少在碰撞期间附接到所述扭杆（17）的另一轴向端部的第二预张紧器（18），以便使所述主轴（12）经由所述扭杆（17）沿所述缩回方向旋转，所述第二预紧器（18）使用 气压。

公开(公告)号：US20100018016A1

公开(公告)日：2010-01-28

申请号：US12522632

申请日：2007-12-03

申请人： Masaki Omiya ,  Kiyoshi Ogawa ,  Atsushi Tsuha

发明人： Masaki Omiya ,  Kiyoshi Ogawa ,  Atsushi Tsuha

IPC分类号： A44B1/08

CPC分类号： B60R22/24 ,  B60R22/203 ,  Y10T24/45524

摘要： A button of a shoulder position adjuster device is provided including an outer surface portion which, at a normal state, is generally continuous with an outer surface of a cover facing an inner space of a passenger compartment. Flexible left and right outer lateral walls are formed continuously with the outer surface portion and have lock portions which are locked on to a side member at the normal state and which are released from the locked state at the time of a pulling operation. Additionally, a pair of connecting walls are provided which extend from the outer surface portion towards a guide rail side in the left and right outer lateral walls and connect the latch pin.

摘要翻译： 提供了一种肩位置调节装置的按钮，其包括外表面部分，该外表面部分在正常状态下与面向乘客室内空间的盖的外表面大致连续。 灵活的左右外侧壁与外表面部分连续地形成，并且具有在正常状态下锁定在侧部构件上并且在拉动操作时从锁定状态释放的锁定部分。 此外，设置一对连接壁，其从外表面部分朝向左外侧壁和右外侧壁中的导轨侧延伸并连接闩锁销。