Mass spectrometer
    2.
    发明授权
    Mass spectrometer 有权
    质谱仪

    公开(公告)号:US08816274B2

    公开(公告)日:2014-08-26

    申请号:US13262217

    申请日:2009-03-31

    摘要: A sample stage (2) on which a sample (4) is placed can be reciprocally moved along a guide (5) by a driving mechanism (6). A cutter (9) which is moved in an X-Y plane by a driving mechanism (10) is placed at a sample cutting position (B). When the sample stage (2) is moved to the sample cutting position (B) and the cutter is driven with the height of the sample stage (2) being appropriately adjusted, an upper portion of the sample 4 is horizontally cut off with a predetermined thickness and a new sample analysis surface which was inside the sample 4 is exposed. Hence, by repeating a mass analysis for a predetermined measurement area at an analysis position (C) and a partial cutting of the sample 4 at the sample cutting position (B), it is possible to achieve a three-dimensional mass analysis imaging of the sample (4) without removing the sample (4) from the sample stage (2).

    摘要翻译: 其上放置有样品(4)的样品台(2)可以通过驱动机构(6)沿引导件(5)往复运动。 通过驱动机构(10)在X-Y平面中移动的切割器(9)被放置在样品切割位置(B)。 当样品台(2)移动到样品切割位置(B)并且在适当调节样品台(2)的高度的情况下驱动切割器时,样品4的上部以预定的 厚度和样品4内部的新的样品分析表面露出。 因此,通过在样本切断位置(B)的分析位置(C)和样本4的部分切割重复对于预定测量区域的质量分析,可以实现三维质量分析成像 样品(4),而不从样品台(2)中移除样品(4)。

    Seatbelt retractor
    3.
    发明授权
    Seatbelt retractor 有权
    安全带卷收器

    公开(公告)号:US08740125B2

    公开(公告)日:2014-06-03

    申请号:US13264870

    申请日:2010-03-31

    IPC分类号: B65H75/48

    摘要: A seatbelt retractor having a switching device with a gas generator and a switch housing having a gas generator housing portion for accommodating the gas generator and a gas flow path that communicates with the gas generator housing portion so that gas generated by the gas generator passes through the gas flow path. Further, the gas generator housing portion and the gas flow path are formed in the switch housing in a curved shape, and a die-cut hole extending in a direction of the gas flow path on an opposite side of the gas flow path to the gas generator housing portion is blocked from the gas flow path by the gas generator.

    摘要翻译: 一种安全带卷收器,具有具有气体发生器的开关装置和具有用于容纳气体发生器的气体发生器容纳部分和与气体发生器壳体部分连通的气体流路的开关壳体,使得由气体发生器产生的气体通过 气体流路。 此外,气体发生器壳体部分和气体流动通道在开关壳体中形成为弯曲形状,并且在气体流动路径的与气体的气体流动路径相对的一侧上延伸的冲切孔 发电机壳体部分被气体发生器从气体流动路径阻挡。

    Mass analysis data processing method and mass spectrometer
    4.
    发明授权
    Mass analysis data processing method and mass spectrometer 有权
    质谱分析数据处理方法和质谱仪

    公开(公告)号:US08612162B2

    公开(公告)日:2013-12-17

    申请号:US13047577

    申请日:2011-03-14

    IPC分类号: H01J49/00 H01J49/26 H01J49/40

    CPC分类号: H01J49/0036 H01J49/408

    摘要: A method creates an accurate mass spectrum with a high resolving power based on a plurality of TOF spectra, while reducing the computation to assure real-time processing. TOF spectra are measured when ions are ejected from the loop orbit. Then a coincidence detection method determines what mass-to-charge ratio a peak appearing on the TOF spectra originates from. The time range in which a corresponding peak appears on other TOF spectra is set, and the existence of the peak in that range is determined. When the corresponding peak is found on other TOF spectra, the m/z is deduced from the peak on the TOF spectrum with the highest resolving power and a mass spectrum is created. From the peak density around the peak of interest, the reliability of the deduction is computed. For a low reliability peak, the ion ejection time is optimized and the TOF spectrum is measured again.

    摘要翻译: 一种方法基于多个TOF谱产生具有高分辨能力的精确质谱,同时减少计算以确保实时处理。 当离子从环轨道弹出时,测量TOF光谱。 然后,重合检测方法确定出现在TOF谱上的峰值的质荷比。 设定其他TOF光谱出现相应峰的时间范围,确定该范围内的峰的存在。 当在其他TOF光谱上发现相应的峰时,从最高分辨能力的TOF谱上的峰值推导出m / z,产生质谱。 从感兴趣峰值附近的峰值密度,计算推导的可靠性。 对于低可靠性峰值,优化离子喷射时间,并再次测量TOF光谱。

    Mass Spectrometer
    5.
    发明申请
    Mass Spectrometer 审中-公开
    质谱仪

    公开(公告)号:US20110315874A1

    公开(公告)日:2011-12-29

    申请号:US13254136

    申请日:2009-03-05

    IPC分类号: H01J49/26

    摘要: When specimen (4) is placed on specimen stage (2), controller (32)—via the stage driver (33) and drive mechanism (6)—moves the specimen stage (2) by a predetermined step pitch according to the magnification factor in the X-direction and the Y-direction, and the image pickup unit (7) acquires a microscopic observation image of the specimen (4) after each move. The microscopic observation image that is acquired and the position data of the specimen stage (2) when the image is acquired are stored in memory (321). When a plurality of microscopic observation images of the areas that are adjacent on the specimen (2) are obtained, the image integration processor (322) uses the position data to join the microscopic observation images. When a plurality of microscopic observation images that encompasses the entirety of the specimen (2) is all joined together to form a specimen observation image, the specimen observation image is displayed on a display unit 37. The user then specifies the desired measurement region based on the specimen observation image that is high in spatial resolution and covering a wide area. Because of this, there is no need to repeat the steps of image pickup and mass spectrometry even when performing a mass spectrometry over a wide area, allowing an efficient measurement.

    摘要翻译: 当样本(4)放置在样本台(2)上时,控制器(32) - 通过平台驱动器(33)和驱动机构(6) - 根据放大系数将样品台(2)以预定的间距移动 在X方向和Y方向上,并且摄像单元(7)在每次移动之后获取样本(4)的显微镜观察图像。 获取的显微镜观察图像和获取图像时的样本台(2)的位置数据被存储在存储器(321)中。 当获得在样本(2)上相邻的区域的多个显微镜观察图像时,图像合成处理器(322)使用位置数据来连接显微镜观察图像。 当包含整个样本(2)的多个显微镜观察图像全部结合在一起以形成样本观察图像时,将样本观察图像显示在显示单元37上。然后,用户基于 空间分辨率高,覆盖面广的样本观察图像。 因此,即使在宽范围内进行质谱分析,也不需要重复图像拾取和质谱分析步骤,从而能够进行有效的测量。

    Mass Spectrometer
    6.
    发明申请
    Mass Spectrometer 有权
    质谱仪

    公开(公告)号:US20110266438A1

    公开(公告)日:2011-11-03

    申请号:US13094659

    申请日:2011-04-26

    IPC分类号: H01J49/26

    CPC分类号: H01J49/0004

    摘要: A mass spectrometer capable of obtaining a clear microscopic observation image with high spatial resolution in real time, even during a mass analysis, without affecting the analysis is provided. An aperture 1a is formed in a stage 1 on which a sample plate 2 to be placed. The sample plate 2 is transparent or translucent. A microscopic observation unit, including an observation optical system 20 and a CCD camera 21, is provided below the stage 1 to observe the reverse side of the sample 3 through the aperture 1a of the stage 1 as well as the transparent sample plate 2. The observed image is displayed on the screen of a display unit 27. If the sample 3 is a slice of biological tissue, the sample image taken from the reverse side will be substantially the same as an image taken from the obverse side.

    摘要翻译: 提供了即使在质量分析期间也能够实时获得具有高空间分辨率的清晰显微镜观察图像的质谱仪,而不影响分析。 孔1a形成在载置样品板2的台1上。 样品板2是透明或半透明的。 包括观察光学系统20和CCD照相机21的显微镜观察单元设置在平台1的下方,通过台1的孔1a以及透明样板2观察样品3的反面。 观察到的图像显示在显示单元27的屏幕上。如果样品3是生物组织的切片,则从背面拍摄的样本图像将与从正面获取的图像基本相同。

    Mass Spectrometer
    7.
    发明申请
    Mass Spectrometer 审中-公开
    质谱仪

    公开(公告)号:US20110121175A1

    公开(公告)日:2011-05-26

    申请号:US12948608

    申请日:2010-11-17

    IPC分类号: H01J49/42

    CPC分类号: H01J49/062 H01J49/0481

    摘要: The present invention aims at enhancing the ion transport efficiency in an ion guide for transporting ions into the subsequent stage while converging the ions by using a collisional cooling method and a radio-frequency electric field. In the present invention, a transport region through which ions pass is divided into an anterior region #1 having a region length L1 and an posterior region #2 having a, region length L2, and the intensity of the direct-current electric field can be set for each of the regions. A direct-current electric field for appropriately accelerating ions is formed in the region #1 so that the collisional cooling of ions is sufficiently performed while the ions are traveling through the region #1 and the ions are sufficiently converged around the ion optical axis C near the end point of the region #1. Meanwhile, in the region #2, a direct-current electric field weaker than that of the region #1 is formed in order to make the converged ions move to the exit plane without allowing them to be dispersed. Consequently, the ions are transported in a sufficiently converged form without remaining in the ion guide, which can achieve a high transport efficiency.

    摘要翻译: 本发明的目的在于提高离子导向器中的离子传输效率,用于将离子输送到后续阶段,同时通过使用碰撞冷却方法和射频电场来收敛离子。 在本发明中,离子通过的输送区域被划分成具有区域长度L1的前部区域#1和具有区域长度L2的后部区域#2,并且直流电场的强度可以是 为每个区域设置。 在区域#1中形成用于适当加速离子的直流电场,使得当离子行进通过区域#1并且离子充分地会聚在离子光轴C附近时离子的碰撞冷却被充分地进行 区域#1的终点。 同时,在区域#2中,形成比区域#1弱的直流电场,以使会聚离子移动到出射面而不使其分散。 因此,离子以足够收敛的形式输送而不残留在离子导向器中,这可以实现高的输送效率。

    SEAT BELT RETRACTOR
    8.
    发明申请
    SEAT BELT RETRACTOR 有权
    座椅皮带扣

    公开(公告)号:US20110121120A1

    公开(公告)日:2011-05-26

    申请号:US12945478

    申请日:2010-11-12

    IPC分类号: B60R22/28 B60R22/34

    摘要: A retractor includes a slide nut that is caused to slide toward a tread head while rotating by a mesh between a first male screw groove and a female screw groove when the tread head is locked and a spindle rotates in a direction for unreeling a webbing, and a slider that is caused to slide toward the slide nut by a mesh between the female screw groove and a second male screw groove. A torsional rigidity of a second shaft part of a torsion bar is larger than that of a first shaft part, and a play is eliminated before a gap such that the slide nut and the slider are integrated.

    摘要翻译: 牵开器包括滑动螺母,当滑动螺母被锁定并且主轴沿用于松开织带的方向旋转时,滑动螺母在通过第一外螺纹槽和内螺纹槽之间的网转动的同时朝向胎面头滑动,以及 滑动件通过内螺纹槽和第二外螺纹槽之间的网状物向滑动螺母滑动。 扭杆的第二轴部的扭转刚性大于第一轴部的扭转刚性,并且在滑动螺母和滑块一体化的间隙之前消除了间隙。

    Mass spectrometer
    9.
    发明授权
    Mass spectrometer 有权
    质谱仪

    公开(公告)号:US07759640B2

    公开(公告)日:2010-07-20

    申请号:US12063625

    申请日:2006-08-10

    IPC分类号: H01J49/04

    CPC分类号: H01J49/0413 H01J49/164

    摘要: In a mass spectrometer for carrying out mass analysis while microscopically observing a two-dimensional area of a sample 15, the observation position for selecting a target portion while observing an image of the sample 15 captured with a CCD camera 23 is separated from the analysis position for carrying out the mass analysis of the sample 15 by delivering laser light from the laser-delivering unit 20 onto the sample 15. The sample 15 is placed on a stage 13, which can be precisely moved between the observation position and the analysis position by a stage-driving mechanism 30. An observation optical system 24 can be set close to the sample 15 at the observation position, without impeding the flight of the ions generated from the sample 15 during the analysis or interfering with a laser-condensing optical system 22. Thus, the spatial resolution for observation is improved without deteriorating the ion-detecting efficiency.

    摘要翻译: 在微观观察样品15的二维区域的质谱分析仪中,在用CCD摄像机23拍摄的样本15的图像上选择目标部位的观察位置与分析位置分离 用于通过将来自激光输送单元20的激光输送到样品15上来对样品15进行质量分析。将样品15放置在台13上,台13可以在观察位置和分析位置之间精确地移动, 阶段驱动机构30.观察光学系统24可以在观察位置处靠近样本15设置,而不会在分析期间产生的样本15的离子的飞行或与激光聚光光学系统22干涉 因此,不会降低离子检测效率,可以提高观察用的空间分辨率。

    MASS SPECTROMETRY APPARATUS AND METHOD
    10.
    发明申请
    MASS SPECTROMETRY APPARATUS AND METHOD 审中-公开
    质谱仪器和方法

    公开(公告)号:US20090230301A1

    公开(公告)日:2009-09-17

    申请号:US12355462

    申请日:2009-01-16

    IPC分类号: B01D59/44 H01J49/10

    CPC分类号: H01J49/4265

    摘要: Disclosed is a mass spectrometry apparatus and method capable of providing enhanced analysis sensitivity in a mass spectrometric analysis for a small amount of ions. A quadrupole rod-type ion guide is employed to temporarily accumulate ions to be introduced into an ion trap, and ions are introduced into the ion guide in an amount less than a saturated ion amount in the ion guide, and accumulated in an exit end of the ion guide. As compared with an octopole rod-type ion guide, the quadrupole rod-type ion guide has a higher ion-converging capability, and therefore can confine and hold a small amount of ions around an ion optical axis, although it is inferior in ion-accumulating capability. This makes it possible to efficiently introduce the ions into the ion trap through two openings of an electric field-correcting electrode and an entrance endcap electrode, so as to perform a high-sensitive analysis.

    摘要翻译: 公开了能够在少量离子的质谱分析中提供增强的分析灵敏度的质谱装置和方法。 采用四极杆型离子导向器暂时积聚离子以引入离子阱,并将离子以小于离子导向器中的饱和离子量的量引入离子导向器中,并且累积在 离子导向。 与八极杆型离子导向器相比,四极杆型离子导向器具有较高的离子收敛能力,因此可以限制和保持离子光轴周围的少量离子,尽管其离子 - 积累能力。 这使得可以通过电场校正电极和入口端帽电极的两个开口有效地将离子引入离子阱中,从而进行高灵敏度分析。