公开(公告)号：US06337201B1

公开(公告)日：2002-01-08

申请号：US09142623

申请日：1998-09-10

申请人： Koji Yanai ,  Akitaka Nakane ,  Hirofumi Nakamura ,  Yuko Baba ,  Akemi Watabe ,  Masao Hirayama

发明人： Koji Yanai ,  Akitaka Nakane ,  Hirofumi Nakamura ,  Yuko Baba ,  Akemi Watabe ,  Masao Hirayama

IPC分类号： C12N924

CPC分类号： C12Y302/01026 ,  C12N9/2431

摘要： A novel &bgr;-fructofuranosidase gene and a &bgr;-fructofuranosidase encoded by the gene, a process for isolating a &bgr;-fructofuranosidase gene using the novel &bgr;-fructofuranosidase gene, and a novel &bgr;-fructofuranosidase obtained by this isolation process are disclosed. A novel mold fungus having no &bgr;-fructofuranosidase activity suitable for the production of &bgr;-fructofuranosidase, and a system for producing a recombinant &bgr;-fructofuranosidase using the novel mold fungus as a host is disclosed. Further, a &bgr;-fructofuranosidase variant which selectively and efficiently produces a specific fructooligosaccharide such as 1-kestose from sucrose is disclosed.

摘要翻译： 公开了一种新颖的β-呋喃果糖苷酶基因和由该基因编码的β-呋喃果糖苷酶，使用新的β-呋喃果糖苷酶基因分离β-呋喃果糖苷酶基因的方法和通过该分离方法获得的新型β-呋喃果糖苷酶。 公开了一种不具有适用于β-呋喃果糖苷酶生产的β-呋喃果糖苷酶活性的新型霉菌，以及使用该新型霉菌作为宿主生产重组β-呋喃果糖苷酶的体系。 此外，公开了一种β-蔗糖呋喃糖苷酶变体，其选择性和有效地产生特定的低聚果糖，例如来自蔗糖的1-kestose。

公开(公告)号：US06921655B1

公开(公告)日：2005-07-26

申请号：US09807933

申请日：1999-10-25

申请人： Yuko Nakamura ,  Tatsuki Moriya ,  Yuko Baba ,  Koji Yanai ,  Naomi Sumida ,  Tomoko Nishimura ,  Kouichirou Murashima ,  Akitaka Nakane ,  Takashi Yaguchi ,  Jinichiro Koga ,  Takeshi Murakami ,  Toshiaki Kono

发明人： Yuko Nakamura ,  Tatsuki Moriya ,  Yuko Baba ,  Koji Yanai ,  Naomi Sumida ,  Tomoko Nishimura ,  Kouichirou Murashima ,  Akitaka Nakane ,  Takashi Yaguchi ,  Jinichiro Koga ,  Takeshi Murakami ,  Toshiaki Kono

IPC分类号： C11D3/386 ,  C12N9/42 ,  C12N15/56 ,  C12P21/06 ,  C07H21/04 ,  C12N9/00 ,  C12N9/24

CPC分类号： C12N9/2437 ,  C11D3/38645 ,  C12Y302/01004

摘要： It is an object of the present invention to provide enzymes that have high endoglucanase activity and yet exhibit high activity even under alkaline conditions, and genes encoding the same. The enzyme according to the invention has the following properties: a) exhibiting endoglucanase activity; and b) capable of completely removing fuzz from regenerated cellulose fabrics at a concentration of 1 mg of the protein/L or below. The enzyme of the invention having endoglucanase activity is a protein comprising the amino acid sequence as shown in SEQ ID NO: 1, 3, 5, 7, 9 or 11; a modified protein thereof exhibiting endoglucanase activity; or a homologue of the protein or the modified protein.

摘要翻译： 本发明的目的是提供具有高内切葡聚糖酶活性并且即使在碱性条件下也表现出高活性的酶，以及编码该酶的基因。 根据本发明的酶具有以下性质：a）显示内切葡聚糖酶活性; 和b）能够以1mg蛋白质/ L或以下的浓度从再生纤维素织物中完全除去绒毛。 具有内切葡聚糖酶活性的本发明的酶是包含如SEQ ID NO：1,3,5,7,9或11所示的氨基酸序列的蛋白质; 其表现出内切葡聚糖酶活性的修饰蛋白质; 或蛋白质或修饰蛋白质的同系物。

公开(公告)号：US07138263B2

公开(公告)日：2006-11-21

申请号：US10276779

申请日：2001-05-22

申请人： Koichiro Murashima ,  Naomi Sumida ,  Akitaka Nakane ,  Koji Yanai ,  Tomoko Nishimura ,  Jinichiro Koga ,  Takeshi Murakami ,  Toshiaki Kono

发明人： Koichiro Murashima ,  Naomi Sumida ,  Akitaka Nakane ,  Koji Yanai ,  Tomoko Nishimura ,  Jinichiro Koga ,  Takeshi Murakami ,  Toshiaki Kono

IPC分类号： C12N9/42 ,  C12N15/00 ,  D21B1/08 ,  C11D3/00 ,  C07H21/04

CPC分类号： C12N9/2437 ,  C11D3/38 ,  C11D3/38645 ,  C12Y302/01004 ,  D06M16/003 ,  D06P5/02 ,  D21C5/005 ,  D21C5/027 ,  D21C9/002 ,  Y02W30/648

摘要： There is provided an endoglucanase enzyme, which is useful for reducing fuzz of regenerated cellulose-containing fabrics, improving the touch and appearance, color clarification, localized variation in color, reducing stiffness and using it as components of a detergent, as well as deinking waste paper and improving freeness of paper pulp. A cDNA coding for the endoglucanase enzyme NCE5 was cloned and its DNA sequence and amino acid sequence derived from it were determined.

摘要翻译： 提供了内切葡聚糖酶，其可用于减少再生含纤维素织物的绒毛，改善触感和外观，颜色澄清，颜色局部变化，降低刚度并将其用作洗涤剂的组分，以及脱墨废物 纸张，提高纸浆的游离度。 克隆编码内切葡聚糖酶NCE5的cDNA，并测定其DNA序列和氨基酸序列。

公开(公告)号：US06566111B1

公开(公告)日：2003-05-20

申请号：US09508264

申请日：2000-03-09

申请人： Koji Yanai ,  Akitaka Nakane ,  Toshiaki Kono

发明人： Koji Yanai ,  Akitaka Nakane ,  Toshiaki Kono

IPC分类号： C12N924

CPC分类号： C12N9/2408 ,  C12Y302/01026

摘要： A novel &bgr;-fructofuranosidase and its gene are disclosed. A polypeptide comprising the amino acid sequence of SEQ ID No. 1 or No. 3 is an enzyme having &bgr;-fructofuranosidase activity and high transferase activity, and is capable of efficiently producing fructooligosaccharides.

摘要翻译： 公开了一种新颖的β-呋喃果糖苷酶及其基因。 包含SEQ ID No.1或3的氨基酸序列的多肽是具有β-呋喃果糖苷酶活性和高转移酶活性的酶，并且能够有效地产生低聚果糖。

公开(公告)号：US20050143275A1

公开(公告)日：2005-06-30

申请号：US10276779

申请日：2001-05-22

申请人： Koichoro Murashima ,  Naomi Sumida ,  Akitaka Nakane ,  Koji Yanai ,  Tomoko Nishimura ,  Jinichiro Koga ,  Takeshi Murakami ,  Toshiaki Kono

发明人： Koichoro Murashima ,  Naomi Sumida ,  Akitaka Nakane ,  Koji Yanai ,  Tomoko Nishimura ,  Jinichiro Koga ,  Takeshi Murakami ,  Toshiaki Kono

IPC分类号： C11D3/38 ,  C11D3/386 ,  C12N1/15 ,  C12N1/19 ,  C12N9/42 ,  C12N15/56 ,  D06M16/00 ,  D06P5/02 ,  D21C5/00 ,  D21C5/02 ,  D21C9/00 ,  C07H21/04 ,  C12N1/16 ,  C12N1/18

CPC分类号： C12N9/2437 ,  C11D3/38 ,  C11D3/38645 ,  C12Y302/01004 ,  D06M16/003 ,  D06P5/02 ,  D21C5/005 ,  D21C5/027 ,  D21C9/002 ,  Y02W30/648

摘要： There is provided an endoglucanase enzyme, which is useful for reducing fuzz of regenerated cellulose-containing fabrics, improving the touch and appearance, color clarification, localized variation in color, reducing stiffness and using it as components of a detergent, as well as deinking waste paper and improving freeness of paper pulp. A cDNA coding for the endoglucanase enzyme NCE5 was cloned and its DNA sequence and amino acid sequence derived from it were determined.

摘要翻译： 提供了内切葡聚糖酶，其可用于减少再生含纤维素织物的绒毛，改善触感和外观，颜色澄清，颜色局部变化，降低刚度并将其用作洗涤剂的组分，以及脱墨废物 纸张，提高纸浆的游离度。 克隆编码内切葡聚糖酶NCE5的cDNA，并测定其DNA序列和氨基酸序列。

公开(公告)号：US09469863B2

公开(公告)日：2016-10-18

申请号：US12734848

申请日：2008-12-01

申请人： Naomi Sumida ,  Koji Yanai ,  Masato Tani ,  Takayoshi Fukushima ,  Yasumasa Ota ,  Shuichi Gomi ,  Akitaka Nakane

发明人： Naomi Sumida ,  Koji Yanai ,  Masato Tani ,  Takayoshi Fukushima ,  Yasumasa Ota ,  Shuichi Gomi ,  Akitaka Nakane

IPC分类号： C07H15/234 ,  C12P19/48 ,  A61K31/7036 ,  C12R1/465

CPC分类号： A61K31/7036 ,  C07H15/234 ,  C12P19/485 ,  C12R1/465 ,  Y02A50/473

摘要： The present invention relates to novel aminoglycoside antibiotics, a process for producing the same, and pharmaceutical use thereof. More specifically, the present invention relates to compounds represented by formula (I), a process for producing the same, and use of the same as antimicrobial agents. wherein R represents amino or hydroxyl.

摘要翻译： 本发明涉及新的氨基糖苷类抗生素，其制备方法及其药物用途。 更具体地说，本发明涉及由式（I）表示的化合物，其制备方法及其作为抗微生物剂的用途。 其中R表示氨基或羟基。

公开(公告)号：US20110034405A1

公开(公告)日：2011-02-10

申请号：US12734848

申请日：2008-12-01

申请人： Naomi Sumida ,  Koji Yanai ,  Masato Tani ,  Takayoshi Fukushima ,  Yasumasa Ota ,  Shuichi Gomi ,  Akitaka Nakane

发明人： Naomi Sumida ,  Koji Yanai ,  Masato Tani ,  Takayoshi Fukushima ,  Yasumasa Ota ,  Shuichi Gomi ,  Akitaka Nakane

IPC分类号： A61K31/7036 ,  C07H15/234 ,  A61P31/00 ,  A61P31/04 ,  C12N1/20 ,  C12P19/04

CPC分类号： A61K31/7036 ,  C07H15/234 ,  C12P19/485 ,  C12R1/465 ,  Y02A50/473

摘要： The present invention relates to novel aminoglycoside antibiotics, a process for producing the same, and pharmaceutical use thereof. More specifically, the present invention relates to compounds represented by formula (I), a process for producing the same, and use of the same as antimicrobial agents. wherein R represents amino or hydroxyl.

摘要翻译： 本发明涉及新的氨基糖苷类抗生素，其制备方法及其药物用途。 更具体地说，本发明涉及由式（I）表示的化合物，其制备方法及其作为抗微生物剂的用途。 其中R表示氨基或羟基。

公开(公告)号：US20080197697A1

公开(公告)日：2008-08-21

申请号：US12071173

申请日：2008-02-15

申请人： Takahiro Naganuma ,  Koji Yanai

发明人： Takahiro Naganuma ,  Koji Yanai

IPC分类号： B60T8/50 ,  B60T8/34

CPC分类号： B60T8/3675

摘要： A hydraulic brake pressure control apparatus has a hydraulic unit having a housing, a casing fixed to the housing, and a circuit board arranged in the casing. A resilient member is disposed between the housing and the casing such that the housing and the casing are separated from each other, in order to reduce vibration transfer from the hydraulic unit to the circuit board. A part of the resilient member is also disposed between a bolt inserted into a through-hole formed in the resilient member and the casing.

摘要翻译： 液压制动压力控制装置具有液压单元，其具有壳体，壳体固定到壳体以及布置在壳体中的电路板。 弹性构件设置在壳体和壳体之间，使得壳体和壳体彼此分离，以便减少从液压单元到电路板的振动传递。 弹性构件的一部分也设置在插入形成在弹性构件的通孔中的螺栓和壳体之间。

公开(公告)号：US07607924B2

公开(公告)日：2009-10-27

申请号：US12022780

申请日：2008-01-30

申请人： Koji Yanai ,  Takayuki Shibata ,  Shoichi Ishikawa

发明人： Koji Yanai ,  Takayuki Shibata ,  Shoichi Ishikawa

IPC分类号： H01R12/00

CPC分类号： H05K7/026 ,  B60T8/3675 ,  H05K1/0263 ,  H05K3/3447 ,  H05K2201/09709 ,  H05K2201/10272 ,  Y10S439/949 ,  Y10T29/49117

摘要： An electronic control unit includes a circuit board, a case, and a group of a plurality of bus bars fixed to the case by insert molding. The bus bars each include a terminal portion having a constant-width portion, and a base portion which is wider than the constant-width portion. The base portions of the respective bus bars are arranged parallel to each other in the width direction thereof. Each bus bar is bent at a bent portion of its base portion. The terminal portion of each bus bar extends through the circuit board and is soldered to and electrically connected to a terminal connecting portion of an electrical circuit on the circuit board at a soldered portion. The bent portions of alternate bus bars are offset from the bent portions of the other bus bars in the longitudinal direction of the bus bars, whereby the soldered portions of the respective terminal portions are arranged in a staggered manner.

摘要翻译： 电子控制单元包括电路板，壳体和通过插入成型固定到壳体的多个汇流条的组。 汇流条各自包括具有恒定宽度部分的端子部分和比恒定宽度部分宽的基部部分。 各母线的基部在宽度方向上彼此平行地配置。 每个汇流条在其基部的弯曲部分处弯曲。 每个母线的端子部分延伸穿过电路板，并焊接到电连接部分的电路板上的电路的端子连接部分并与之电连接。 备用汇流条的弯曲部分在汇流条的长度方向上偏离其它汇流条的弯曲部分，由此相应端子部分的焊接部分以交错方式排列。

公开(公告)号：US07513482B2

公开(公告)日：2009-04-07

申请号：US11589896

申请日：2006-10-31

申请人： Takayuki Shibata ,  Koji Yanai ,  Toru Fujita ,  Tomoaki Kawabata

发明人： Takayuki Shibata ,  Koji Yanai ,  Toru Fujita ,  Tomoaki Kawabata

IPC分类号： F16K31/02

CPC分类号： B60T8/363 ,  B60T8/368 ,  F16K27/003 ,  F16K31/0675 ,  Y10S251/903

摘要： A solenoid valve for use in an actuator for controlling brake hydraulic pressure includes a valve housing, a movable core having an integral valve rod and axially slidably received in the valve housing, and a valve body configured to be moved into and out of contact with a valve seat when the valve body moves. The solenoid valve further includes a yoke having a U-shaped section. The flanges of the yoke have first ends that extend substantially along the outer peripheral edges of the coil winding to minimize the length of the flanges and thus the length of the solenoid valve.

摘要翻译： 一种用于控制制动液压的致动器的电磁阀包括阀壳体，具有一体式阀杆并可轴向可滑动地容纳在阀壳体中的可动芯体，以及被配置成移动进入和脱离接触的阀体 阀体运动时阀座。 电磁阀还包括具有U形截面的轭。 轭的凸缘具有基本上沿着线圈绕组的外周缘延伸的第一端，以最小化凸缘的长度并因此使电磁阀的长度最小化。