-
公开(公告)号：US5304483A
公开(公告)日：1994-04-19
申请号：US493369
申请日：1990-03-14
摘要： Stable, long-term cultures of animal cells are accomplished by calculating the ratio of lactic acid formed by the cells to the glucose consumed by the cells (the L/G ratio) and controlling the cultivation conditions to maintain the L/G ratio between the limits of from greater than 0 to 0.6. When the ratio is outside the desired range, the dissolved oxygen concentration in the medium is increased and/or the glucose concentration in the medium is decreased.
摘要翻译： 通过计算由细胞形成的乳酸与细胞消耗的葡萄糖的比例（L / G比），并控制培养条件以维持L / G比例的L / G比，来实现动物细胞的稳定的长期培养 极限从0到0.6。 当比例在所需范围之外时，介质中的溶解氧浓度增加和/或介质中的葡萄糖浓度降低。
-
2.发明授权Apparatus containing a septum which impedes cell permeation for cell culture and method of use 失效含有阻碍细胞培养的细胞渗透的隔膜和使用方法的装置
公开(公告)号：US5151362A
公开(公告)日：1992-09-29
申请号：US505326
申请日：1990-04-05
CPC分类号： C12M29/04 , C12M29/10 , C12M41/00 , Y10S435/813
摘要： By culturing cells in an apparatus containing a first zone in which a cell suspended medium is present and a second zone in which liquid containing a physiological saline solution and/or nutrient sources is present, the first zone being separated from the second zone by a septum with characteristics, such as pores size or electrostatic charges, which impedes the cells from freely permeating through, while allowing at least one of nutrient sources, cell wastes or the product to move between the first zone and the second zone via the septum to proliferate cells in the first zone, wherein a flow rate via the septum is controlled in such a manner that the cell count moved from the first zone into the second zone via the septum does not exceed the cell count increased by cell growth in the first zone. Thus, cell culture at a high cell density can be achieved in a large scale.
摘要翻译： 通过在包含存在细胞悬浮介质的第一区域和存在含有生理盐水溶液和/或营养源的液体的第二区域的装置中培养细胞，第一区域通过隔膜与第二区域分离 具有阻止细胞自由渗透的特征，例如孔径或静电电荷，同时允许营养源，细胞废物或产物中的至少一种通过隔膜在第一区和第二区之间移动以增殖细胞 在第一区域中，其中以通过隔膜从第一区域移动到第二区域的方式控制经由隔膜的流速不超过由第一区域中的细胞生长增加的细胞计数。 因此，可以大规模地实现高细胞密度的细胞培养。
-
3.发明授权Wiper device, method for manufacturing wiper device, and apparatus for manufacturing wiper device 有权刮水装置，刮水装置的制造方法以及刮水装置的制造装置公开(公告)号：US09216716B2
公开(公告)日：2015-12-22
申请号：US13810173
申请日：2012-05-15
申请人： Shinji Murata , Kouji Takeuchi , Kenta Toriyama , So Asano
发明人： Shinji Murata , Kouji Takeuchi , Kenta Toriyama , So Asano
CPC分类号： B60S1/06 , B60S1/0425 , B60S1/0433 , B60S1/0436 , B60S1/0438
摘要： A wiper device includes pivot shafts to which wiper arms are secured, pivot holders, which rotationally support the pivot shafts, coupling shafts, and a pipe frame having cylindrical ends. The cylindrical ends of the pipe frame are coupled to the coupling shafts. The coupling shafts each include a swaging part, which is swaged to the corresponding cylindrical end, and a flat portion, which is located at part of the coupling shaft exposed from the pipe frame. The flat portions have a predetermined angle with respect to the swaging direction of the swaging and are parallel to the axis of the coupling shafts.
摘要翻译： 刮水器装置包括固定有刮水器臂的枢转轴，枢转保持器，其旋转地支撑枢转轴，联接轴以及具有圆柱形端部的管框架。 管框的圆柱端连接到联轴器上。 连接轴各自包括挤压到相应的圆柱端的型锻部，以及位于从管框露出的连接轴的一部分处的平坦部。 平坦部分相对于型锻的型锻方向具有预定的角度并且平行于联接轴的轴线。
-
4.发明申请WIPER DEVICE, METHOD FOR MANUFACTURING WIPER DEVICE, AND APPARATUS FOR MANUFACTURING WIPER DEVICE 有权刮水装置，制造刮水装置的方法以及制造刮水装置的装置公开(公告)号：US20130111690A1
公开(公告)日：2013-05-09
申请号：US13810173
申请日：2012-05-15
申请人： Shinji Murata , Kouji Takeuchi , Kenta Toriyama , So Asano
发明人： Shinji Murata , Kouji Takeuchi , Kenta Toriyama , So Asano
IPC分类号： B60S1/06
CPC分类号： B60S1/06 , B60S1/0425 , B60S1/0433 , B60S1/0436 , B60S1/0438
摘要： A wiper device includes pivot shafts to which wiper arms are secured, pivot holders, which rotationally support the pivot shafts, coupling shafts, and a pipe frame having cylindrical ends. The cylindrical ends of the pipe frame are coupled to the coupling shafts. The coupling shafts each include a swaging part, which is swaged to the corresponding cylindrical end, and a flat portion, which is located at part of the coupling shaft exposed from the pipe frame. The flat portions have a predetermined angle with respect to the swaging direction of the swaging and are parallel to the axis of the coupling shafts.
摘要翻译： 刮水器装置包括固定有刮水器臂的枢转轴，枢转保持器，其旋转地支撑枢转轴，联接轴以及具有圆柱形端部的管框架。 管框的圆柱端连接到联轴器上。 连接轴各自包括挤压到相应的圆柱端的型锻部，以及位于从管框露出的连接轴的一部分处的平坦部。 平坦部分相对于型锻的型锻方向具有预定的角度并且平行于联接轴的轴线。
-
公开(公告)号：US20100256346A1
公开(公告)日：2010-10-07
申请号：US12087180
申请日：2006-12-25
申请人： Hirosuke Oku , Hironori Iwasaki , Kensaku Takara , Hisami Watanabe , Goro Matsuzaki , Takahiro Ishikawa , Kouji Takeuchi , Akira Taira
发明人： Hirosuke Oku , Hironori Iwasaki , Kensaku Takara , Hisami Watanabe , Goro Matsuzaki , Takahiro Ishikawa , Kouji Takeuchi , Akira Taira
IPC分类号： C07H15/10
CPC分类号： A61K36/899 , C07H15/10
摘要： To provide a pharmaceutical composition comprising a ceramide-related substance having little adverse side effects as an active ingredient by using a raw material that is highly safe to a human body and is inexpensive. A pharmaceutical composition comprising at least one sphingoglycolipid derivative that is produced from a beer waste and is represented by the formula below as an active ingredient: wherein R3 represents H or OH; R4 is as defined by (a) or (b): (a) when R3 is H, R4 represents (CH2)13CH3 or (CH2)6CH═CHCH2CH═CH(CH2)4CH3; and (b) when R3 is OH, R4 represents (CH2)yCH3 (where Y represents an integer of 13 to 21) or (CH2)z1CH═CH(CH2)Z2CH3 (where Z1 and Z2 independently represent 0 or a natural number, provided that Z1+Z2=19).
摘要翻译： 为了提供一种药物组合物，其通过使用对人体高度安全的原料廉价地提供作为有效成分的，具有很少副作用的神经酰胺相关物质。 一种药物组合物，其包含至少一种由啤酒废物产生的神经鞘糖脂衍生物，并由下式表示为活性成分：其中R 3表示H或OH; R 4如（a）或（b）所定义：（a）当R 3为H时，R 4表示（CH 2）13 CH 3或（CH 2）6 CH = CHCH 2 CH = CH（CH 2）4 CH 3; 和（b）当R3为OH时，R4表示（CH2）yCH3（其中Y表示13-21的整数）或（CH2）z1CH = CH（CH2）Z2CH3（其中Z1和Z2独立地表示0或自然数， 条件是Z1 + Z2 = 19）。
-
公开(公告)号：US4218352A
公开(公告)日：1980-08-19
申请号：US956363
申请日：1978-10-31
摘要： A molten material is prepared by heating a mixture of (A) a polyhydric alcohol containing a neopentyl structure such as pentaerythritol, dipentaerythritol or tripentaerythritol which is less compatible with a halogen-containing resin and (B) a partial ester of said polyhydric alcohol and a carboxyl group-containing compound which has good compatibility with the halogen-containing resin to the molten state. The molten material functions as a stabilizer assistant which markedly increases the thermal stabilizing effect of divalent metal stabilizers for the halogen-containing resin.
摘要翻译： 通过加热（A）含有与含卤素树脂较不相容的季戊四醇，二季戊四醇或三季戊四醇等新戊基结构的多元醇的混合物和（B）所述多元醇的部分酯和 与含卤素树脂具有良好相容性的含羧基化合物的熔融状态。 熔融材料起稳定助剂的作用，显着提高了含二价金属稳定剂对含卤树脂的热稳定作用。
-
公开(公告)号：US08293162B2
公开(公告)日：2012-10-23
申请号：US11791771
申请日：2005-11-29
申请人： Hiroshi Yokoyama , Hiroshige Okamoto , Muneaki Aminaka , Kouji Takeuchi , Hironobu Yamauchi , Ken Someya
发明人： Hiroshi Yokoyama , Hiroshige Okamoto , Muneaki Aminaka , Kouji Takeuchi , Hironobu Yamauchi , Ken Someya
CPC分类号： C08G63/785
摘要： A method for producing a molded product consisting of a resin polymerized by a melt polycondensation reaction, comprising continuous feeding of a prepolymer in molten state from a prepolymer feeding port to a polymerization reactor, discharging from holes of a porous plate, followed by polymerization while dropping along a supporting substrate under reduced pressure, and molding by transferring to at least one molding machine in molten state without solidification, wherein transfer pressure to said molding machine is controlled so as to maintain at an arbitrary pressure from 0.1 to 100 MPa (absolute pressure).
摘要翻译： 一种制备由熔融缩聚反应聚合的树脂组成的模制产品的方法，包括将熔融状态的预聚物从预聚物进料口连续供入聚合反应器，从多孔板的孔排出，然后滴加聚合 在减压下沿着支撑基板进行模塑，并且通过在熔融状态下转移至至少一个成型机而不固化而成型，其中控制到所述成型机的转印压力以保持在0.1〜100MPa（绝对压力）的任意压力， 。
-
公开(公告)号：USD664519S1
公开(公告)日：2012-07-31
申请号：US29396369
申请日：2011-06-29
-
公开(公告)号：USD386376S
公开(公告)日：1997-11-18
申请号：US58614
申请日：1996-08-13
申请人： Tetsuhisa Kaneko , Kouji Takeuchi
设计人： Tetsuhisa Kaneko , Kouji Takeuchi
-
公开(公告)号：US20130022641A1
公开(公告)日：2013-01-24
申请号：US13630850
申请日：2012-09-28
申请人： Hirosuke Oku , Hironori Iwasaki , Kensaku Takara , Hisami Watanabe , Goro Matsuzaki , Takahiro Ishikawa , Kouji Takeuchi , Akira Taira
发明人： Hirosuke Oku , Hironori Iwasaki , Kensaku Takara , Hisami Watanabe , Goro Matsuzaki , Takahiro Ishikawa , Kouji Takeuchi , Akira Taira
IPC分类号： A61K31/7028 , A61P37/04 , A61P35/00 , C07H15/10
CPC分类号： A61K36/899 , C07H15/10
摘要： To provide a pharmaceutical composition comprising a ceramide-related substance having little adverse side effects as an active ingredient by using a raw material that is highly safe to a human body and is inexpensive. A pharmaceutical composition comprising at least one sphingoglycolipid derivative that is produced from a beer waste and is represented by the formula below as an active ingredient: wherein R3 represents H or OH; R4 is as defined by (a) or (b) (a) when R3 is H, R4 represents (CH2)13CH3 or (CH2)6CH═CHCH2CH═CH(CH2)4CH3; and (b) when R3 is OH, R4 represents (CH2)yCH3 (where Y represents an integer of 13 to 21) or (CH2)Z1CH═CH(CH2)Z2CH3 (where Z1 and Z2 independently represent 0 or a natural number, provided that Z1+Z2=19).
摘要翻译： 为了提供一种药物组合物，其通过使用对人体高度安全的原料廉价地提供作为有效成分的，具有很少副作用的神经酰胺相关物质。 一种药物组合物，其包含至少一种由啤酒废物产生的神经鞘糖脂衍生物，并由下式表示为活性成分：其中R 3表示H或OH; 当R 3为H时，R 4如（a）或（b）（a）所定义，R 4表示（CH 2）13 CH 3或（CH 2）6 CH = CHCH 2 CH = CH（CH 2）4 CH 3; 和（b）当R3是OH时，R4表示（CH2）yCH3（其中Y表示13-21的整数）或（CH2）Z1CH = CH（CH2）Z2CH3（其中Z1和Z2独立地表示0或自然数， 条件是Z1 + Z2 = 19）。
-
-
-
-
-
-
-
-
-
搜索结果
11 条记录 (耗时 0.022 秒)