公开(公告)号：US20180361345A1

公开(公告)日：2018-12-20

申请号：US15978523

申请日：2018-05-14

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Robert Hess ,  John Linton ,  Tanya S. Kanigan ,  Colin Brenan ,  Can Ozbal

IPC: B01J19/00 ,  G01N30/60 ,  C12M1/32 ,  B01L3/00

Abstract: The invention features methods of making devices, or “platens”, having a high-density array of through-holes, as well as methods of cleaning and refurbishing the surfaces of the platens. The invention further features methods of making high-density arrays of chemical, biochemical, and biological compounds, having many advantages over conventional, lower-density arrays. The invention includes methods by which many physical, chemical or biological transformations can be implemented in serial or in parallel within each addressable through-hole of the devices. Additionally, the invention includes methods of analyzing the contents of the array, including assaying of physical properties of the samples.

公开(公告)号：US09968903B2

公开(公告)日：2018-05-15

申请号：US15131101

申请日：2016-04-18

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Robert Hess ,  John Linton ,  Tanya S. Kanigan ,  Colin Brenan ,  Can Ozbal

IPC: B01J19/00 ,  B01L3/02 ,  B01L3/00 ,  C40B60/14 ,  G01N30/46 ,  G01N30/60 ,  B01L99/00 ,  C12M1/32 ,  G01N30/82 ,  G01N30/84

CPC classification number: B01J19/0046 ,  B01J2219/00317 ,  B01J2219/00319 ,  B01J2219/00351 ,  B01J2219/0036 ,  B01J2219/00369 ,  B01J2219/00387 ,  B01J2219/00389 ,  B01J2219/00423 ,  B01J2219/0043 ,  B01J2219/00479 ,  B01J2219/00495 ,  B01J2219/005 ,  B01J2219/00511 ,  B01J2219/00585 ,  B01J2219/00587 ,  B01J2219/00596 ,  B01J2219/00648 ,  B01J2219/00653 ,  B01J2219/00659 ,  B01J2219/00673 ,  B01L3/0244 ,  B01L3/0262 ,  B01L3/0268 ,  B01L3/5025 ,  B01L3/50255 ,  B01L3/5085 ,  B01L3/50857 ,  B01L99/00 ,  B01L2200/0657 ,  B01L2300/0845 ,  C12M23/12 ,  C40B60/14 ,  G01N30/466 ,  G01N30/6091 ,  G01N30/6095 ,  G01N30/82 ,  G01N2030/8417

Abstract: The invention features methods of making devices, or “platens”, having a high-density array of through-holes, as well as methods of cleaning and refurbishing the surfaces of the platens. The invention further features methods of making high-density arrays of chemical, biochemical, and biological compounds, having many advantages over conventional, lower-density arrays. The invention includes methods by which many physical, chemical or biological transformations can be implemented in serial or in parallel within each addressable through-hole of the devices. Additionally, the invention includes methods of analyzing the contents of the array, including assaying of physical properties of the samples.