公开(公告)号：US20070293671A1

公开(公告)日：2007-12-20

申请号：US11631980

申请日：2005-07-06

申请人： Laszlo Czibula ,  Peter Turcsanyi ,  Krisztina Feher ,  Ferenc Sebok ,  Gyorgy Szabo ,  Eva Papp

发明人： Laszlo Czibula ,  Peter Turcsanyi ,  Krisztina Feher ,  Ferenc Sebok ,  Gyorgy Szabo ,  Eva Papp

IPC分类号： C07D239/70

CPC分类号： C07D471/04

摘要： The invention relates to a process for the preparation of risperidone (chemical name: 3-[2-[4-(6-fluoro-1,2-benzisoxazole-3-yl)-1piperidmyl]ethyl-2-methyl-6,7,8,9-terahydro-4H-pyrido[1,2-a]pyrimidine-4-one) of the formula (I) by reacting 3-(2-chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidine-4-one of the formula (II) and 6-fluoro-3-(4-piperidinyl)-1,2-benzisoxazole of the formula (III), in which the reaction is carried out in dry methanol solvent under pressure, at a temperature between 65 and 90° C., the product is recovered by using a methanol/water mixture of specified ratio and if desired is recrystallized from an alcohol.

摘要翻译： 本发明涉及制备利培酮（化学名称：3- [2- [4-（6-氟-1,2-苯并异恶唑-3-基）-1-哌啶基]乙基-2-甲基-6,7 ，8,9-四氢-4H-吡啶并[1,2-a]嘧啶-4-酮）通过使3-（2-氯乙基）-2-甲基-6,7,8,9 （II）的6-四氢-4H-吡啶并[1,2-a]嘧啶-4-酮和式（III）的6-氟-3-（4-哌啶基）-1,2-苯并异恶唑在 其反应在无水甲醇溶剂中在压力下在65至90℃的温度下进行，通过使用规定比例的甲醇/水混合物回收产物，如果需要，从醇中重结晶。

公开(公告)号：US5206558A

公开(公告)日：1993-04-27

申请号：US691327

申请日：1991-04-29

申请人： Zoltan Losonczi ,  Gyorgy Szabo

发明人： Zoltan Losonczi ,  Gyorgy Szabo

IPC分类号： H01K7/02 ,  F21V17/04 ,  F21V19/00

CPC分类号： F21V19/0005 ,  F21V17/04

摘要： A light source includes a reflector, a lamp and a securing mechanism firmly fixing the lamp to the reflector. The reflector includes a reflecting portion and a central hollow neck portion having an inner surface. The lamp includes an envelope provided with a pinch-sealed portion; a light emitting component accommodated in the envelope; and current feedthroughs electrically connected to the light emitting components and passing through the pinch-sealed portion to project outwardly from the envelope. The securing mechanism includes a first metal sleeve tightly surrounding the pinch-sealed portion of the envelope; a second metal sleeve lining the inner surface of the neck portion of the reflector and surrounding the first metal sleeve; and clamping components affixed to the second sleeve. The clamping components fit into the hollow neck portion and encase the inner surface thereof from two opposite sides. The first and second metal sleeves are fixedly secured to one another.

公开(公告)号：US5354390A

公开(公告)日：1994-10-11

申请号：US41441

申请日：1993-03-31

申请人： Karoly Haszmann ,  Lajos Kovacs ,  Kalman Vargha ,  Imre Juhasz ,  Gyorgy Szabo

发明人： Karoly Haszmann ,  Lajos Kovacs ,  Kalman Vargha ,  Imre Juhasz ,  Gyorgy Szabo

IPC分类号： A61F2/00 ,  A61F2/30 ,  A61L27/06 ,  C25D11/26 ,  C21D11/00 ,  C23F13/00

CPC分类号： A61L27/06 ,  A61C8/0015 ,  C25D11/26 ,  A61F2002/30927 ,  A61F2310/00023

摘要： The invention relates to a new process for obtaining tissue-protective devices of bone surgery implants prepared from a medical-purity metal, titanium and/or a titanium-base microalloy containing at least 98% by weight of titanium, by establishing a biocompatible (tissue-protective) coating on the metal surface by anodic oxidation after degreasing and chemical or electrochemical etching, which comprises carrying out the anodic oxidation of the etched implant surfaces in an aqueous solution of a phosphate concentration lower than 20% by weight with a current density of 2 to 50 mA/cm.sup.2 until reaching a voltage of at least 105 V, then, after washing to ion-free, heat-treating the thus-oxidized implants at a temperature between 120.degree. C. and 750.degree. C. for 5 to 120 minutes, and repeating once or twice the anodic oxidation and heat-treatment with the phosphate concentration, current density and temperature values as given above for the first step.

摘要翻译： 本发明涉及一种用于获得由含有至少98重量％钛的医用纯度金属，钛和/或钛基微合金制备的骨手术植入物的组织保护装置的新方法，通过建立生物相容性（组织 保护）在脱脂和化学或电化学蚀刻之后通过阳极氧化在金属表面上涂覆，其包括在低于20重量％的磷酸盐浓度的水溶液中进行蚀刻的植入物表面的阳极氧化，电流密度 2至50mA / cm 2，直到达到至少105V的电压，然后在120至750℃之间的温度下洗涤至无离子的方式将这样氧化的植入物热处理5至120 分钟，并重复一次或两次阳极氧化和热处理，磷酸盐浓度，电流密度和温度值如上文第一步所述。

公开(公告)号：US20090036510A1

公开(公告)日：2009-02-05

申请号：US11989439

申请日：2006-07-27

申请人： Janos Fischer ,  Istvanne Kis-Varga ,  Gyorgy Szabo ,  Janos Leibinger

发明人： Janos Fischer ,  Istvanne Kis-Varga ,  Gyorgy Szabo ,  Janos Leibinger

IPC分类号： A61K31/415 ,  C07D231/12 ,  A61P29/00

CPC分类号： C07D231/12

摘要： The present invention relates to new compounds of formula (I), (I) wherein the meaning of R1 is hydrogen atom, C1-C5 acyl group, benzoyl group or R2—COOR3 group, Y is hydrogen atom or alkali ion, R2 is C1-C4 straight or branched alkylidene group and R3 is hydrogen atom, C1-C4 alkyl group or alkali ion, and/or stereoisomers and/or diastereomers and/or pharmaceutically acceptable salts and/or hydrates and/or solvates thereof, which are suitable for the treatment of pain of acute and chronic inflammation origin as well as postoperative pain and dysmenorrhea. The invention also relates to the process of the synthesis of compounds of formula (I) as well as the pharmaceutical composition containing the same and the use for treatment of pain, inflammation and disorders associated with inflammation.

摘要翻译： 本发明涉及式（I），（I）的新化合物，其中R1的含义是氢原子，C1-C5酰基，苯甲酰基或R2-COOR3基，Y是氢原子或碱离子，R2是C1 -C4直链或支链亚烷基和R 3是氢原子，C 1 -C 4烷基或碱金属离子，和/或立体异构体和/或非对映异构体和/或其药学上可接受的盐和/或水合物和/或溶剂化物， 治疗急性和慢性炎症原因的疼痛以及术后疼痛和痛经。 本发明还涉及式（I）化合物的合成方法以及含有该化合物的药物组合物和用于治疗与炎症相关的疼痛，炎症和病症的用途。

公开(公告)号：US4870318A

公开(公告)日：1989-09-26

申请号：US166124

申请日：1988-03-09

申请人： Istvan Csanyi ,  Janos Csiszar ,  Laszla Feher ,  Zoltan Losonczi ,  Gyorgy Szabo

发明人： Istvan Csanyi ,  Janos Csiszar ,  Laszla Feher ,  Zoltan Losonczi ,  Gyorgy Szabo

IPC分类号： G03B21/14 ,  F21S2/00 ,  F21V7/22 ,  F21V9/00 ,  G02B5/28

CPC分类号： F21V9/00 ,  F21V7/22 ,  G02B5/285

摘要： The invention refers to a projector lamp, which comprises a light source (3), a mirror (1) arranged in a space relationship to the light source (3) for projecting the light emitted by the light source (3) in a predetermined direction, the mirror (1) having a surface determined by a carrier element made of glass or plastics, and a layer system covering the surface of the mirror (1) and including layers characterized by refractive indices alternately at least 2.0 and at most 1.7. The improvement lies in applying layer system including at least four layers (4, 5, 6, 7) prepared for reflecting respective color components of the light emitted by the light source (3). The proposed projector lamp is capable of emitting color light without applying filters.

摘要翻译： 本发明涉及一种投影灯，其包括光源（3），与光源（3）以空间关系布置的反射镜（1），用于将光源（3）发射的光沿预定方向投影 具有由玻璃或塑料制成的载体元件确定的表面的反射镜（1）和覆盖反射镜（1）的表面的层系统，并且包括折射率交替为至少2.0和至多1.7的层。 改进在于应用层系统，其包括至少四层（4,5,6,7），其准备用于反射由光源（3）发射的光的各个颜色分量。 所提出的投影灯能够在不使用过滤器的情况下发出彩色光。

公开(公告)号：US5101138A

公开(公告)日：1992-03-31

申请号：US628142

申请日：1990-12-17

申请人： Zoltan Losonczi ,  Emil Czako ,  Gyorgy Szabo ,  Gyorgy Orsanyi

发明人： Zoltan Losonczi ,  Emil Czako ,  Gyorgy Szabo ,  Gyorgy Orsanyi

IPC分类号： H01K1/24 ,  H01K1/16 ,  H01K1/40

CPC分类号： H01K1/16

摘要： A halogen-filled incandescent lamp includes a curved tube enclosure made of a translucent material and enclosing a gas filling and an incandescent body made of a tungsten wire helix of circular wire cross-section. The incandescent body is arranged within the enclosure. Two inside current conductors connect the incandescent body with an energizing device. Each inside current conductor has first and second spiral members and an elongated part forming together a series assembly. The series assembly is connected via the second spiral member with the incandescent body and via the first spiral member with the energizing device. The series assembly is at least partly made of a wire having a cross-sectional area exceeding that of the tungsten wire forming the incandescent body.

公开(公告)号：US4013335A

公开(公告)日：1977-03-22

申请号：US592793

申请日：1975-07-02

申请人： Laszlo Varkonyi ,  Gyorgy Szabo ,  Jozsef Orto ,  Laszlo Nagy ,  Janos Spielmann ,  Gyorgy Rabatin ,  Istvan Pozsonyi

发明人： Laszlo Varkonyi ,  Gyorgy Szabo ,  Jozsef Orto ,  Laszlo Nagy ,  Janos Spielmann ,  Gyorgy Rabatin ,  Istvan Pozsonyi

IPC分类号： H01J5/54 ,  H01J5/56

CPC分类号： H01J5/54 ,  H01J5/56

摘要： An improved construction for a lamp cap suitable for interconnecting the elongated constricted neck of a halogen lamp to an electrode-bearing lamp holder is described. A hollow elongated deformable insert is coaxially positioned within a conventional cover disc of the lamp cap. The interior dimension of the insert is chosen to effect a secure frictional engagement with at least 30% of the length of the constricted lamp neck, and is permanently or removably affixed to the surrounding cover disc. The lamp holder may then be affixed to the composite lamp cap to complete the assembly.

摘要翻译： 描述了适用于将卤素灯的细长收缩颈部与电极轴承灯座相互连接的灯帽的改进结构。 中空细长可变形插入件同轴地定位在灯帽的传统盖盘内。 选择插入件的内部尺寸以实现与收缩的灯颈长度的至少30％的牢固的摩擦接合，并且永久地或可移除地固定到周围的盖盘上。 然后可以将灯座固定到复合灯帽以完成组装。

公开(公告)号：US5176441A

公开(公告)日：1993-01-05

申请号：US785154

申请日：1991-10-28

申请人： Gyozone Horvath dr.nee Vegh ,  Zoltan Losonczi ,  Gyorgy Szabo

发明人： Gyozone Horvath dr.nee Vegh ,  Zoltan Losonczi ,  Gyorgy Szabo

IPC分类号： H01K1/34

CPC分类号： H01K1/34

摘要： In a lamp with a reflector envelope ensuring modified light output, comprising a conical reflecting body (2), an insert light source (4) arranged within the conical reflecting body (2) and a light transmitting front element (3) fixed to the conical reflecting body (2), there is between the conical reflecting body (2) and the front element (3) a clearance (10) determined by the dimensions and the inner spring force of a mechanical fixing body (5) connecting the conical reflecting body (2) and the front element (3), wherein at least a part of the clearance (10) is occupied by a deformable sealing material (6) or adhesive.

摘要翻译： 在具有确保改变的光输出的反射器外壳的灯中，包括锥形反射体（2），布置在锥形反射体（2）内的插入光源（4）和固定到圆锥形反射体 反射体（2）之间，在锥形反射体（2）和前部元件（3）之间存在由连接圆锥体反射体（5）的机械固定体（5）的尺寸和内部弹簧力确定的间隙（10） （2）和所述前部元件（3），其中所述间隙（10）的至少一部分被可变形密封材料（6）或粘合剂占据。

公开(公告)号：US5073742A

公开(公告)日：1991-12-17

申请号：US482847

申请日：1990-02-22

申请人： Gyula Busai ,  Gyorgyi Vegh ,  Zoltan Losonczi ,  Akos Ocsovai ,  Istvan Pozsonyi ,  Gyorgy Szabo ,  Gyorgy Vajo

发明人： Gyula Busai ,  Gyorgyi Vegh ,  Zoltan Losonczi ,  Akos Ocsovai ,  Istvan Pozsonyi ,  Gyorgy Szabo ,  Gyorgy Vajo

IPC分类号： H01K1/42 ,  H01K1/46 ,  H01L21/60

CPC分类号： H01K1/46

摘要： In an incandescent lamp, comprising a translucent envelope (2) having flattened end (3) of rectangular cross-section, a base element (5) surrounding the flattened end part (3) and having rectangular cross-section, two current lead-ins (7a, 7b) connected with an incandescent body (4) arranged within the envelope (2) and with the base element (5) and thereby with a connecting cable (8), a centering plate (6) with a rectangular opening for receiving the base element (5), wherein the centering plate (6) is made with at least one flange element (10) arranged on the side of the centering plate (6) not facing the envelope (2), the base element (5) being made with thinner plate than the centering plate (6), a locating body (9) stepwisely shaped for receiving the flange element (10) is applied, the locating body (9) made with thinner wall than the centering plate (6) is fixed on the base element (5), has an edge (14) separated from the base element (5) by a gap, wherein the edge (14) of the locating body (9) covers at least partly the at least one flange element (10) of the centering plate (6), the flange element (10) of the centering plate (6) is between the base element (5) and the locating body (9), further the flange element (10) of the centering plate (6) and the locating body (9) are connected by a thermal method of joining.

摘要翻译： 在白炽灯中，包括具有矩形横截面的扁平端（3）的半透明外壳（2），包围扁平端部（3）并且具有矩形横截面的基座元件（5），两个电流引线 （7a，7b），与布置在外壳（2）内的白炽体（4）连接，与基座元件（5）连接，由此连接电缆（8），具有矩形开口的定心板（6） 所述基座元件（5），其中所述定心板（6）制成有至少一个凸缘元件（10），所述至少一个凸缘元件（10）布置在所述定心板（6）的不面向所述外壳（2）的侧面上，所述基座元件（5） 被制成具有比定中板（6）更薄的板，施加了逐步成形为用于容纳凸缘元件（10）的定位体（9），与定中心板（6）相比形成有较薄壁的定位体（9） 固定在基体元件（5）上，具有通过间隙与基底元件（5）分离的边缘（14），其中该位置的边缘（14） 至少部分地覆盖所述定心板（6）的所述至少一个凸缘元件（10），所述定心板（6）的所述凸缘元件（10）位于所述基座元件（5）和所述定位板 主体（9），另外，定心板（6）的凸缘元件（10）和定位体（9）通过热连接方式连接。