摘要:
Methods for altering the natural history of degenerative disc disease and osteoarthritis of the spine are proposed. The methods focus on the prevention, or delayed onset or progression of, subchondral defects such as bone marrow edema or bone marrow lesion, and subchondral treatment to prevent the progression of osteoarthritis or degenerative disc disease in the spine and thereby treat pain.
摘要:
Methods for altering the natural history of degenerative disc disease and osteoarthritis of the spine are proposed. The methods focus on the prevention, or delayed onset or progression of, subchondral defects such as bone marrow edema or bone marrow lesion, and subchondral treatment to prevent the progression of osteoarthritis or degenerative disc disease in the spine and thereby treat pain.
摘要:
Methods for altering the natural history of degenerative disc disease and osteoarthritis of the spine are proposed. The methods focus on the prevention, or delayed onset or progression of, subchondral defects such as bone marrow edema or bone marrow lesion, and subchondral treatment to prevent the progression of osteoarthritis or degenerative disc disease in the spine and thereby treat pain.
摘要:
A method of using an interbody spinal implant by implanting the spinal implant into a patient in need of the spinal implant. The method includes accessing the disc space of the patient and locating the center of the disc space. The disc space is incised by making a window in the annulus of the disc space for insertion of the spinal implant. The endplates are cleaned of all cartilage and the disc structure, which is encapsulated by the annulus, is removed while avoiding damage to the endplate structure of the vertebrae. Optionally a size-specific rasp is selected and the disc space is cleared of all soft tissue and cartilage. Optionally the disc space is distracted by sequentially expanding it with distractors of progressively increasing heights. A spinal implant having a pre-determined size sufficient to balance frictional fit and elongation of the annulus is selected and seated in the disc space.
摘要:
An implant (4) is provided with attachment and hole-insert parts (2, 3) with surfaces which have different degrees of finishing and/or degrees of roughness and/or porosities (2f, 2g). Arranged on the surfaces there is at least one dozen (A-B) in which the degree of finishing and/or the degree of roughness and/or the porosity is continuously changed. The changes in porosity in said zones can mirror continuous or discontinuous changes in the bone in question, for example the jaw bone or tooth bone. The continuously changed zones can be obtained with the aid of electrolyte (15) and, connected to the latter, an anode and cathode arrangement (13, 14). When establishing the porosity, it is possible to mask different portions of the respective implant and to control the temperature of the implant.
摘要:
An apparatus for distracting a disc space having an annulus. The apparatus includes a spinal implant having a pre-determined size sufficient to balance frictional fit in the disc space and elongation of the annulus. The implant has a top surface, a bottom surface, opposing lateral sides, and opposing anterior and posterior portions defining a substantially hollow center and a single vertical aperture. At least one of the opposing anterior and posterior portions presents a substantially flat impact face including an opening with an instrument retention feature. The apparatus also includes a rasp, a plurality of distractors, and an instrument able to engage and manipulate the spinal implant, the rasp, and the plurality of distractors. The size-specific rasp is adapted to clear the disc space of all soft tissue and cartilage. The plurality of distractors have progressively increasing heights adapted to distract the disc space before use of the spinal implant.
摘要:
Methods for altering the natural history of degenerative disc disease and osteoarthritis of the spine are proposed. The methods focus on the prevention, or delayed onset or progression of, subchondral defects such as bone marrow edema or bone marrow lesion, and subchondral treatment to prevent the progression of osteoarthritis or degenerative disc disease in the spine and thereby treat pain.
摘要:
An interbody spinal implant having at least three distinct surfaces including (1) at least one integration surface having a roughened surface topography including macro features, micro features, and nano features, without sharp teeth that risk damage to bone structures; (2) at least one graft contact surface having a coarse surface topography including micro features and nano features; and (3) at least one soft tissue surface having a substantially smooth surface including nano features. Also disclosed are processes of fabricating the different surface topographies, which may include separate macro processing, micro processing, and nano processing steps.
摘要:
A method of producing an interbody spinal implant. The method includes the steps of obtaining a blank having a top surface, bottom surface, opposing lateral sides, and opposing anterior and posterior portions, and applying a subtractive process (e.g., masked acid etching) to the top surface, the bottom surface, or both surfaces of the blank to form a roughened surface topography. Subsequently, the blank is machined to form the interbody spinal implant, which includes a body having a top surface, a bottom surface, opposing lateral sides, opposing anterior and posterior portions, a substantially hollow center, and a single vertical aperture where the top surface, the bottom surface, or both surfaces of the interbody spinal implant have the roughened surface topography produced by the subtractive process. This simplified method produces more accurate and repeatable implants with fewer process steps and defects, reducing process time and costs.
摘要:
Processes for producing interbody spinal implants having a body with a top surface, a bottom surface, opposing lateral sides, opposing anterior and posterior portions, a substantially hollow center, and a single vertical aperture; and optionally, one or two integration plates affixed to the body. The processes include applying an additive process, a subtractive process, or both processes to at least one surface of the interbody spinal implant to form a roughened surface topography having a regular repeating pattern. The roughened surface topography is specifically designed to provide certain frictional characteristics, load dispersion, and to influence the biological responses that occur during bone healing and fusion.