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公开(公告)号：US07402608B2
公开(公告)日：2008-07-22
申请号：US10730272
申请日：2003-12-09
申请人： Laval Chan Chun Kong , Sanjoy Kumar Das , Nghe Nguyen-Ba , Liliane Halab , Oswy Z. Pereira , Carl Poisson , Melanie Proulx , Thumkunta Jagadeeswar Reddy , Zhang Ming-Qiang
发明人： Laval Chan Chun Kong , Sanjoy Kumar Das , Nghe Nguyen-Ba , Liliane Halab , Oswy Z. Pereira , Carl Poisson , Melanie Proulx , Thumkunta Jagadeeswar Reddy , Zhang Ming-Qiang
IPC分类号： A61K31/381 , C07D333/10
CPC分类号： C07D333/36 , A61K31/381 , A61K31/4535 , A61K31/55 , A61K45/00 , C07D333/40 , C07D409/12
摘要： Compounds represented by formula: wherein X, Y and Z are as defined herein, pharmaceutically acceptable salts thereof, and related compounds, are suitable for use in treating or preventing a Flaviviridae viral infection in a host.
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2.发明授权Compounds and methods for the treatment or prevention of flavivirus infections 失效用于治疗或预防黄病毒感染的化合物和方法公开(公告)号：US08357718B2
公开(公告)日：2013-01-22
申请号：US12068237
申请日：2008-02-04
申请人： Laval Chan Chun Kong , Sanjoy Kumar Das , Nghe Nguyen-Ba , Liliane Halab , Bettina Hamelin , Oswy Z. Pereira , Carl Poisson , Melanie Proulx , Thumkunta Jagadeeswar Reddy , Zhang Ming-Qiang
发明人： Laval Chan Chun Kong , Sanjoy Kumar Das , Nghe Nguyen-Ba , Liliane Halab , Bettina Hamelin , Oswy Z. Pereira , Carl Poisson , Melanie Proulx , Thumkunta Jagadeeswar Reddy , Zhang Ming-Qiang
IPC分类号： A61K31/381 , C07D333/10
CPC分类号： C07D333/36 , A61K31/381 , A61K31/4535 , A61K31/55 , A61K45/00 , C07D333/40 , C07D409/12
摘要： Compounds represented by formula: wherein X, Y and Z are as defined herein, pharmaceutically acceptable salts thereof, and related compounds, are suitable for use in treating or preventing a Flaviviridae viral infection in a host.
摘要翻译： 由下式表示的化合物：其中X，Y和Z如本文所定义，其药学上可接受的盐和相关化合物适用于治疗或预防宿主中的黄病毒科病毒感染。
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3.发明申请Compounds and methods for the treatment or prevention of Flavivirus infections 失效用于治疗或预防黄病毒感染的化合物和方法公开(公告)号：US20080269481A1
公开(公告)日：2008-10-30
申请号：US12068237
申请日：2008-02-04
申请人： Laval Chan Chun Kong , Sanjoy Kumar Das , Nghe Nguyen-Ba , Liliane Halab , Bettina Hamelin , Oswy Z. Pereira , Carl Poisson , Melaine Proulx , Thumkunta Jagadeeswar Reddy , Zhang Ming-Qiang
发明人： Laval Chan Chun Kong , Sanjoy Kumar Das , Nghe Nguyen-Ba , Liliane Halab , Bettina Hamelin , Oswy Z. Pereira , Carl Poisson , Melaine Proulx , Thumkunta Jagadeeswar Reddy , Zhang Ming-Qiang
IPC分类号： C07D409/12 , C07D333/38
CPC分类号： C07D333/36 , A61K31/381 , A61K31/4535 , A61K31/55 , A61K45/00 , C07D333/40 , C07D409/12
摘要： Compounds represented by formula: wherein X, Y and Z are as defined herein, pharmaceutically acceptable salts thereof, and related compounds, are suitable for use in treating or preventing a Flaviviridae viral infection in a host.
摘要翻译： 由下式表示的化合物：其中X，Y和Z如本文所定义，其药学上可接受的盐和相关化合物适用于治疗或预防宿主中的黄病毒科病毒感染。
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4.发明授权Compounds and methods for the treatment or prevention of Flavivirus infections 失效用于治疗或预防黄病毒感染的化合物和方法公开(公告)号：US06881741B2
公开(公告)日：2005-04-19
申请号：US10166031
申请日：2002-06-11
申请人： Laval Chan Chun Kong , Jean Bedard , Sanjoy Kumar Das , Nghe Nguyen Ba , Oswy Z. Pereira , Thumkunta Jagadeeswar Reddy , Mohammad Arshad Siddiqui , Wuyi Wang , Constanin Yannopoulos
发明人： Laval Chan Chun Kong , Jean Bedard , Sanjoy Kumar Das , Nghe Nguyen Ba , Oswy Z. Pereira , Thumkunta Jagadeeswar Reddy , Mohammad Arshad Siddiqui , Wuyi Wang , Constanin Yannopoulos
IPC分类号： C07D333/40 , A61K31/20 , A61K31/341 , A61K31/343 , A61K31/381 , A61K31/382 , A61K31/4025 , A61K31/4035 , A61K31/404 , A61K31/41 , A61K31/4155 , A61K31/42 , A61K31/426 , A61K31/427 , A61K31/433 , A61K31/437 , A61K31/4436 , A61K31/4535 , A61K31/454 , A61K31/4709 , A61K31/4725 , A61K31/496 , A61K31/55 , A61K45/00 , A61K45/06 , A61P1/16 , A61P31/12 , C07D333/38 , C07D333/62 , C07D409/04 , C07D409/06 , C07D409/12 , C07D409/14 , C07D417/04 , C07D417/12 , C07D417/14 , C07D419/14 , C07D471/10 , C07D495/04 , C07F7/10 , A61K31/44 , A61K31/38 , C07D211/70 , C07D333/36 , C07D401/00
CPC分类号： C07D409/04 , A61K31/20 , A61K31/341 , A61K31/343 , A61K31/381 , A61K31/426 , A61K45/06 , C07D333/38 , C07D409/06 , C07D409/12 , C07D409/14 , C07D417/04 , C07D417/12 , C07D417/14 , C07D419/14 , C07D471/10 , C07D495/04
摘要： The present invention provides novel compounds represented by formula I: or pharmaceutically acceptable salts thereof useful for treating flaviviridae viral infection.
摘要翻译： 本发明提供由式I表示的新化合物：或其药学上可接受的盐，用于治疗黄病毒科病毒感染。
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5.发明授权Compounds and methods for the treatment or prevention of Flavivirus infections 失效用于治疗或预防黄病毒感染的化合物和方法公开(公告)号：US07985769B2
公开(公告)日：2011-07-26
申请号：US11042442
申请日：2005-01-26
申请人： Laval Chan Chun Kong , Jean Bedard , Sanjoy Kumar Das , Nghe Nguyen Ba , Oswy Z. Pereira , Thumkunta Jagadeeswar Reddy , Mohammad Arshad Siddiqui , Wuyi Wang , Constanin Yannopoulos
发明人： Laval Chan Chun Kong , Jean Bedard , Sanjoy Kumar Das , Nghe Nguyen Ba , Oswy Z. Pereira , Thumkunta Jagadeeswar Reddy , Mohammad Arshad Siddiqui , Wuyi Wang , Constanin Yannopoulos
IPC分类号： A61K31/35 , C07D333/38 , C07D333/36
CPC分类号： C07D409/04 , A61K31/20 , A61K31/341 , A61K31/343 , A61K31/381 , A61K31/426 , A61K45/06 , C07D333/38 , C07D409/06 , C07D409/12 , C07D409/14 , C07D417/04 , C07D417/12 , C07D417/14 , C07D419/14 , C07D471/10 , C07D495/04
摘要： The present invention provides novel compounds represented by formula I: or pharmaceutically acceptable salts thereof useful for treating flaviviridae viral infection.
摘要翻译： 本发明提供由式I表示的新化合物：或其药学上可接受的盐，用于治疗黄病毒科病毒感染。
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6.发明申请COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS 审中-公开用于治疗或预防FLAVIVIRUSUS感染的化合物和方法公开(公告)号：US20130123242A1
公开(公告)日：2013-05-16
申请号：US13661508
申请日：2012-10-26
申请人： Laval Chan Chun Kong , Jean Bedard , Sanjoy Kumar Das , Nghe Nguyen-Ba , Oswy Z. Pereira , Thumkunta Jagadeeswar Reddy , Mohammad Arshad Siddiqui , Wuyi Wang , Constantin G. Yannopoulos
发明人： Laval Chan Chun Kong , Jean Bedard , Sanjoy Kumar Das , Nghe Nguyen-Ba , Oswy Z. Pereira , Thumkunta Jagadeeswar Reddy , Mohammad Arshad Siddiqui , Wuyi Wang , Constantin G. Yannopoulos
IPC分类号： C07D333/40 , C07D409/14 , C07D417/12 , C07D409/04 , C07D409/10 , C07D417/04 , C07D409/12 , C07D471/10
CPC分类号： C07D333/40 , A61K31/381 , A61K45/06 , C07D333/38 , C07D409/04 , C07D409/06 , C07D409/10 , C07D409/12 , C07D409/14 , C07D417/04 , C07D417/12 , C07D417/14 , C07D419/14 , C07D471/10 , C07D495/04
摘要： The present invention provides novel compounds represented by formula I: or pharmaceutically acceptable salts thereof useful for treating flaviviridae viral infection.
摘要翻译： 本发明提供由式I表示的新化合物：或其药学上可接受的盐，用于治疗黄病毒科病毒感染。
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7.发明授权Compounds and methods for the treatment or prevention of flavivirus infections 失效用于治疗或预防黄病毒感染的化合物和方法公开(公告)号：US06936629B2
公开(公告)日：2005-08-30
申请号：US10324140
申请日：2002-12-20
申请人： Laval Chan Chun Kong , Oswy Z. Pereira , Nghe Nguyen-Ba , Thumkunta Jagadeeswar Reddy , Sanjoy Kumar Das , Mohammad Arshad Siddiqui
发明人： Laval Chan Chun Kong , Oswy Z. Pereira , Nghe Nguyen-Ba , Thumkunta Jagadeeswar Reddy , Sanjoy Kumar Das , Mohammad Arshad Siddiqui
IPC分类号： A61P31/14 , C07D277/56 , A61K31/426 , C07D277/20
CPC分类号： C07D277/56
摘要： The present invention provides novel compounds represented by formula I: or pharmaceutically acceptable salts thereof useful for treating flaviviridae viral infection.
摘要翻译： 本发明提供由式I表示的新化合物：或其药学上可接受的盐，用于治疗黄病毒科病毒感染。
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8.发明授权Compounds and methods for the treatment or prevention of Flavivirus infections 失效用于治疗或预防黄病毒感染的化合物和方法公开(公告)号：US08329924B2
公开(公告)日：2012-12-11
申请号：US13081780
申请日：2011-04-07
申请人： Laval Chan Chun Kong , Jean Bedard , Sanjoy Kumar Das , Nghe Nguyen-Ba , Oswy Z. Pereira , Thumkunta Jagadeeswar Reddy , Mohammad Arshad Siddiqui , Wuyi Wang , Constantin G. Yannopoulos
发明人： Laval Chan Chun Kong , Jean Bedard , Sanjoy Kumar Das , Nghe Nguyen-Ba , Oswy Z. Pereira , Thumkunta Jagadeeswar Reddy , Mohammad Arshad Siddiqui , Wuyi Wang , Constantin G. Yannopoulos
IPC分类号： C07D409/00 , C07D333/42
CPC分类号： C07D333/40 , A61K31/381 , A61K45/06 , C07D333/38 , C07D409/04 , C07D409/06 , C07D409/10 , C07D409/12 , C07D409/14 , C07D417/04 , C07D417/12 , C07D417/14 , C07D419/14 , C07D471/10 , C07D495/04
摘要： The present invention provides novel compounds represented by formula I: or pharmaceutically acceptable salts thereof useful for treating flaviviridae viral infection.
摘要翻译： 本发明提供由式I表示的新化合物：或其药学上可接受的盐，用于治疗黄病毒科病毒感染。
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9.发明申请COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS 失效用于治疗或预防FLAVIVIRUSUS感染的化合物和方法公开(公告)号：US20110200553A1
公开(公告)日：2011-08-18
申请号：US13081780
申请日：2011-04-07
申请人： Laval Chan Chun Kong , Jean Bedard , Sanjoy Kumar Das , Nghe Nguyen Ba , Oswy Z. Pereira , Thumkunta Jagadeeswar Reddy , Mohammed Arshad Siddiqui , Wuyi Wang , Constanin G. Yannopoulos
发明人： Laval Chan Chun Kong , Jean Bedard , Sanjoy Kumar Das , Nghe Nguyen Ba , Oswy Z. Pereira , Thumkunta Jagadeeswar Reddy , Mohammed Arshad Siddiqui , Wuyi Wang , Constanin G. Yannopoulos
IPC分类号： A61K31/381 , C07D333/36 , C07D409/12 , A61K31/4535 , A61K31/438 , A61K31/496 , A61K31/55 , A61K38/21 , A61K31/7056 , A61K38/20 , A61K38/13 , A61P31/12
CPC分类号： C07D333/40 , A61K31/381 , A61K45/06 , C07D333/38 , C07D409/04 , C07D409/06 , C07D409/10 , C07D409/12 , C07D409/14 , C07D417/04 , C07D417/12 , C07D417/14 , C07D419/14 , C07D471/10 , C07D495/04
摘要： The present invention provides novel compounds represented by formula I: or pharmaceutically acceptable salts thereof useful for treating flaviviridae viral infection.
摘要翻译： 本发明提供由式I表示的新化合物：或其药学上可接受的盐，用于治疗黄病毒科病毒感染。
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10.发明授权Compounds and methods for the treatment or prevention of Flavivirus infections 失效用于治疗或预防黄病毒感染的化合物和方法公开(公告)号：US06887877B2
公开(公告)日：2005-05-03
申请号：US10166030
申请日：2002-06-11
申请人： Laval Chan Chun Kong , Jean Bedard , Sanjoy Kumar Das , Nghe Nguyen Ba , Oswy Z. Pereira , Stephen Joseph Shuttleworth , Mohammad Arshad Siddiqui , Wuyi Wang
发明人： Laval Chan Chun Kong , Jean Bedard , Sanjoy Kumar Das , Nghe Nguyen Ba , Oswy Z. Pereira , Stephen Joseph Shuttleworth , Mohammad Arshad Siddiqui , Wuyi Wang
IPC分类号： C07D233/64 , A61K31/13 , A61K31/198 , A61K31/277 , A61K31/341 , A61K31/343 , A61K31/381 , A61K31/40 , A61K31/41 , A61K31/415 , A61K31/4174 , A61K31/42 , A61K31/423 , A61K31/426 , A61K31/427 , A61K31/44 , A61K31/4406 , A61K31/4425 , A61K31/443 , A61K31/4436 , A61K31/4468 , A61K31/47 , A61K31/7056 , A61K31/7084 , A61K36/28 , A61K38/00 , A61K38/21 , A61K38/22 , A61K38/46 , A61K38/55 , A61K45/00 , A61K48/00 , A61P1/16 , A61P31/04 , A61P31/12 , A61P37/02 , A61P43/00 , C07C233/51 , C07C233/87 , C07C235/20 , C07C255/60 , C07C311/19 , C07C311/29 , C07C317/32 , C07D207/09 , C07D207/48 , C07D211/58 , C07D213/40 , C07D213/89 , C07D215/12 , C07D231/20 , C07D233/54 , C07D257/04 , C07D261/08 , C07D263/56 , C07D263/57 , C07D277/20 , C07D277/28 , C07D277/32 , C07D277/34 , C07D277/42 , C07D277/58 , C07D307/46 , C07D307/52 , C07D307/54 , C07D307/56 , C07D307/68 , C07D307/80 , C07D307/81 , C07D333/20 , C07D333/24 , C07D333/28 , C07D333/30 , C07D333/36 , C07D333/38 , C07D405/04 , C07D407/04 , C07D409/04 , C07D409/14 , C07D411/12 , C07D417/04
CPC分类号： C07D213/40 , A61K31/341 , A61K31/343 , A61K31/381 , A61K31/426 , A61K31/44 , C07C233/87 , C07C255/60 , C07C311/19 , C07C311/29 , C07C317/32 , C07D207/48 , C07D211/58 , C07D215/12 , C07D231/20 , C07D233/64 , C07D257/04 , C07D261/08 , C07D263/57 , C07D277/28 , C07D277/32 , C07D277/42 , C07D277/58 , C07D307/46 , C07D307/52 , C07D307/81 , C07D333/20 , C07D333/28 , C07D333/38 , C07D407/04 , C07D409/04 , C07D409/14 , C07D411/12 , C07D417/04
摘要： The present invention provides novel compounds represented by formula I: or pharmaceutically acceptable salts thereof useful for treating Flaviviridae viral infection.
摘要翻译： 本发明提供了可用于治疗黄病毒科病毒感染的由式I表示的新化合物或其药学上可接受的盐。
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