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公开(公告)号：US4784657A
公开(公告)日：1988-11-15
申请号：US939576
申请日：1986-12-09
CPC分类号： A61J1/2096 , A61J1/2065
摘要： An interconnect connects a vial to a syringe for the transfer of material to the syringe or back to the vial. The interconnect includes a vial connecting mechanism and a tapered sleeve to receive the syringe. A metering port allows control of the material transfer rate and prevents partial transfers which could cause material spillage.
摘要翻译： 互连将小瓶连接到注射器以将材料转移到注射器或返回到小瓶。 互连包括小瓶连接机构和锥形套筒以接收注射器。 计量端口允许控制材料转移速率，并防止可能导致材料溢出的部分转移。
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公开(公告)号：USD303427S
公开(公告)日：1989-09-12
申请号：US872762
申请日：1986-06-10
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公开(公告)号：US06358532B2
公开(公告)日：2002-03-19
申请号：US09788103
申请日：2001-02-15
IPC分类号： A61K914
CPC分类号： B01J20/282 , A61F2/30767 , A61F2002/2817 , A61F2002/30242 , A61F2002/3025 , A61F2230/0071 , A61F2310/00293 , A61F2310/00796 , A61K9/1611 , A61K9/501 , A61L27/12 , A61L31/026 , B01J20/048 , B01J20/28004 , B01J20/28011 , B01J20/28019 , B01J20/28021 , B01J20/2803 , B01J2220/54 , C01B25/32
摘要： The present invention provides calcium phosphate-based (CaP) microcarriers and their use, for example, in cell culturing systems, chromatography, and implantable biomedical materials.
摘要翻译： 本发明提供了基于磷酸钙的（CaP）微载体及其在细胞培养系统，色谱和可植入生物医学材料中的用途。
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公开(公告)号：US08389017B1
公开(公告)日：2013-03-05
申请号：US10030578
申请日：2000-07-07
CPC分类号： A61L27/3608 , A61K9/501 , A61K33/06 , A61K35/12 , A61K45/06 , A61L27/12 , A61L27/50 , A61L27/54 , A61L2300/114 , C12N5/0075 , C12N5/0654 , C12N2533/18 , A61K31/155 , A61K31/195 , A61K2300/00
摘要： The present invention generally relates to calcium-containing structures and methods of making and using the structures. In one aspect, hollow calcium containing microstructures are used in conjunction with bone tissues/by-products to augment bone defects and extend the supply of bone tissues/by-products for bone augmentation. Bonding agents, such as calcium cements, are also used in the preparation of the hollow calcium microstructures combined with bone tissues/by-products or for use in preparing the hollow microstructures. The calcium-containing microstructures of the present invention are also useful as delivery vehicles of nitric oxide and/or nitric oxide containing or producing compounds for a variety of in vitro and in vivo uses. Calcium containing contoured substrates upon which cells/tissues can be grown in vitro for replacement and repair of tissues in vivo that conform in size and shape to the tissue surface to be replaced are also provided.
摘要翻译： 本发明一般涉及含钙结构及其制造和使用方法。 在一个方面，含空心钙微结构与骨组织/副产物结合使用，以增加骨缺损并延长骨组织/副产物的供应以增加骨骼。 粘结剂，例如钙粘结剂，也用于制备与骨组织/副产物组合的中空钙微结构或用于制备中空微结构。 本发明的含钙微结构也可用作含有或用于各种体外和体内用途的化合物的一氧化氮和/或一氧化氮的输送载体。 还提供含钙成分的基质，细胞/组织可以在其上体外生长，用于体内组织的组织替换和修复，其尺寸和形状与待替换的组织表面一致。
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公开(公告)号：US06210715B1
公开(公告)日：2001-04-03
申请号：US09402308
申请日：2000-02-02
IPC分类号： A61K914
CPC分类号： B01J20/282 , A61F2/30767 , A61F2002/2817 , A61F2002/30242 , A61F2002/3025 , A61F2230/0071 , A61F2310/00293 , A61F2310/00796 , A61K9/1611 , A61K9/501 , A61L27/12 , A61L31/026 , B01J20/048 , B01J20/28004 , B01J20/28011 , B01J20/28019 , B01J20/28021 , B01J20/2803 , B01J2220/54 , C01B25/32
摘要： The present invention provides calcium phosphate-based (CAP) microcarriers and microspheres and their use in cell culturing systems, chromatography and implantable biomedical materials.
摘要翻译： 本发明提供了基于磷酸钙的（CAP）微载体和微球及其在细胞培养系统，色谱和可植入生物医学材料中的应用。
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公开(公告)号：US4839215A
公开(公告)日：1989-06-13
申请号：US872617
申请日：1986-06-09
CPC分类号： A61F2/30756 , A61C8/0012 , A61F2/0063 , A61F2/28 , A61L27/02 , A61L27/12 , A61F2002/0068 , A61F2002/30009 , A61F2002/302 , A61F2002/30235 , A61F2002/30909 , A61F2002/30914 , A61F2230/0065 , A61F2230/0069 , A61F2250/0028 , A61F2310/00293 , Y10S525/937 , Y10T428/24273 , Y10T428/24322 , Y10T428/24331 , Y10T428/25 , Y10T428/252 , Y10T428/254 , Y10T428/256 , Y10T428/2982
摘要： Biocompatible particles and an article incorporating a plurality of such particles is disclosed. The particles can have means for interconnecting such as an aperture for stringing the particles on a filament or interlocking external shape. A plurality of particles, with or without means for interconnecting, can be fashioned into an article by interconnecting the particles with a flexible material. When the particles have a means for interconnecting, the plurality of particles can also be interconnected by a rigid material. The particles or plurality of interconnected particles are useful for medical, dental or veterinary or biotechnical applications, such as bone, tooth or skin implants, including alveolar ridge augmentation, or as a growth substrate material. Any biocompatible material can be used, including ceramics such a hydroxylapatite.
摘要翻译： 公开了生物相容性颗粒和包含多个这样的颗粒的制品。 颗粒可以具有用于互连的装置，例如用于将颗粒缠绕在细丝上或互锁外部形状上的孔。 具有或不具有互连的装置的多个颗粒可以通过将颗粒与柔性材料相互连接而形成制品。 当颗粒具有用于互连的装置时，多个颗粒也可以通过刚性材料互连。 颗粒或多个相互连接的颗粒可用于医疗，牙科或兽医或生物技术应用，例如骨，牙齿或皮肤植入物，包括牙槽嵴隆起或作为生长基质材料。 可以使用任何生物相容性材料，包括陶瓷如羟基磷灰石。
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