IN SITU HEAT INDUCED ANTIGEN RECOVERY AND STAINING APPARATUS AND METHOD
    1.
    发明申请
    IN SITU HEAT INDUCED ANTIGEN RECOVERY AND STAINING APPARATUS AND METHOD 有权
    在原发热诱导的抗原恢复和染色设备和方法

    公开(公告)号:US20110312085A1

    公开(公告)日:2011-12-22

    申请号:US13220438

    申请日:2011-08-29

    Applicant: Lee Angros

    Inventor: Lee Angros

    Abstract: An automated in situ heat induced antigen recovery and staining method and apparatus for treating a plurality of microscope slides. The process of heat induced antigen recovery and the process of staining the biological sample on the microscope slide are conducted in the same apparatus, wherein the microscope slides do not need to be physically removed from one apparatus to another. Each treatment step occurs within the same reaction compartment. The reaction conditions of each reaction compartment for treating a slide can preferably be controlled independently, including the individualized application of reagents to each slide and the individualized treatment of each slide. The reagents are preferably held in a reagent dispensing strip similar to a “blister pack”.

    Abstract translation: 一种用于处理多个显微镜载片的自动原位热诱导抗原恢复和染色方法和装置。 在相同的装置中进行热诱导的抗原恢复过程和在显微镜载玻片上染色生物样品的过程,其中显微镜幻灯片不需要从一个装置物理移除到另一个装置。 每个处理步骤发生在相同的反应室内。 用于处理载玻片的每个反应室的反应条件可以独立地进行控制,包括各载玻片的各种试剂的应用以及各载玻片的个体化处理。 试剂优选保持在类似于“泡罩包装”的试剂分配条中。

    IN SITU HEAT INDUCED ANTIGEN RECOVERY AND STAINING APPARATUS AND METHOD
    3.
    发明申请
    IN SITU HEAT INDUCED ANTIGEN RECOVERY AND STAINING APPARATUS AND METHOD 有权
    在原发热诱导的抗原恢复和染色设备和方法

    公开(公告)号:US20110150725A1

    公开(公告)日:2011-06-23

    申请号:US13036873

    申请日:2011-02-28

    Abstract: Contemplated herein is an automated microscope slide antigen recovery and staining apparatus and method that features a plurality of individually operable miniaturized pressurizable reaction compartments for individually and independently processing a plurality of individual microscope slides. The apparatus preferably features independently movable slide support elements each having an individually heatable heating plate. Each slide support element preferably supports a single microscope slide. Each microscope slide can be enclosed within an individual pressurizable reaction compartment. Pressures exceeding 1 atm or below 1 atm can be created and maintained in the reaction compartment prior to, during or after heating of the slide begins. Because of the ability to pressurize and regulate pressure within the reaction compartment, and to individually heat each slide, each slide and a liquid solution or reagent thereon can be heated to temperatures that could not be obtained without the enclosed pressurized environment of the reaction compartment. A reagent dispensing strip having a plurality of reconfigurable reagent modules may also be used.

    Abstract translation: 本文考虑的是自动显微镜载玻片抗原恢复和染色装置和方法,其特征在于具有多个单独可操作的小型可加压反应室,用于单独和独立地处理多个单独的显微镜载玻片。 该装置优选地具有各自具有可单独加热的加热板的可独立移动的滑动支撑元件。 每个滑动支撑元件优选地支撑单个显微镜载玻片。 每个显微镜载玻片可以封闭在单独的可加压反应室内。 超过1 atm或低于1 atm的压力可以在滑块开始加热之前,期间或之后产生并保持在反应室中。 由于能够对反应室内的压力进行加压和调节,并且单独地加热每个载玻片,所以每个载玻片及其上的液体溶液或试剂可以被加热到在没有反应室的封闭的加压环境的情况下不能获得的温度。 还可以使用具有多个可重新配置的试剂模块的试剂分配条。

    In situ heat induced antigen recovery and staining apparatus and method
    4.
    发明授权
    In situ heat induced antigen recovery and staining apparatus and method 有权
    原位热诱导抗原回收染色装置及方法

    公开(公告)号:US07476362B2

    公开(公告)日:2009-01-13

    申请号:US10943546

    申请日:2004-09-17

    Applicant: Lee Angros

    Inventor: Lee Angros

    Abstract: An automated in situ heat induced antigen recovery and staining method and apparatus for treating a plurality of microscope slides. The process of heat induced antigen recovery and the process of staining the biological sample on the microscope slide are conducted in the same apparatus, wherein the microscope slides do not need to be physically removed from one apparatus to another. Each treatment step occurs within the same reaction compartment. The reaction conditions of each reaction compartment for treating a slide can preferably be controlled independently, including the individualized application of reagents to each slide and the individualized treatment of each slide. The reagents are preferably held in a reagent dispensing strip similar to a “blister pack”.

    Abstract translation: 一种用于处理多个显微镜载片的自动原位热诱导抗原恢复和染色方法和装置。 在相同的装置中进行热诱导的抗原恢复过程和在显微镜载玻片上染色生物样品的过程,其中显微镜幻灯片不需要从一个装置物理移除到另一个装置。 每个处理步骤发生在相同的反应室内。 用于处理载玻片的每个反应室的反应条件可以独立地进行控制,包括各载玻片的各种试剂的应用以及各载玻片的个体化处理。 试剂优选保持在类似于“泡罩包装”的试剂分配条中。

    IN SITU HEAT INDUCED ANTIGEN RECOVERY AND STAINING APPARATUS AND METHOD
    5.
    发明申请
    IN SITU HEAT INDUCED ANTIGEN RECOVERY AND STAINING APPARATUS AND METHOD 有权
    在原发热诱导的抗原恢复和染色设备和方法

    公开(公告)号:US20080318305A1

    公开(公告)日:2008-12-25

    申请号:US12198692

    申请日:2008-08-26

    Applicant: Lee Angros

    Inventor: Lee Angros

    Abstract: An automated in situ heat induced antigen recovery and staining method and apparatus for treating a plurality of microscope slides. The process of heat induced antigen recovery and the process of staining the biological sample on the microscope slide are conducted in the same apparatus, wherein the microscope slides do not need to be physically removed from one apparatus to another. Each treatment step occurs within the same reaction compartment. The reaction conditions of each reaction compartment for treating a slide can preferably be controlled independently, including the individualized application of reagents to each slide and the individualized treatment of each slide. The reagents are preferably held in a reagent dispensing strip similar to a “blister pack”.

    Abstract translation: 一种用于处理多个显微镜载片的自动原位热诱导抗原恢复和染色方法和装置。 在相同的装置中进行热诱导的抗原恢复过程和在显微镜载玻片上染色生物样品的过程,其中显微镜幻灯片不需要从一个装置物理移除到另一个装置。 每个处理步骤发生在相同的反应室内。 用于处理载玻片的每个反应室的反应条件可以独立地进行控制,包括各载玻片的各种试剂的应用以及各载玻片的个体化处理。 试剂优选保持在类似于“泡罩包装”的试剂分配条中。

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